| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Braun, B Mullone. Cholinergic modulation of the swimmeret motor system in crayfish. Journal of neurophysiology. vol 70. issue 6. 1994-04-06. PMID:7907133. |
the acetylcholine (ach) analogue carbachol combined the effects of pilocarpine and nicotine. |
1994-04-06 |
2023-08-12 |
Not clear |
| A M Vidal, J del Castillo, D S Smit. Contractile properties of the articular capsule or ligament, in the primary spines of the sea-urchin Eucidaris tribuloides. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 106. issue 3. 1994-03-15. PMID:7905803. |
the articular capsule or ligament, of the primary spines of the sea-urchin eucidaris tribuloides behaves as a classical excitable tissue, responding with a shortening or contracture to a variety of stimuli including the cholinergic agonists acetylcholine (ach), methacholine (meach), carbamylcholine (cch) and nicotine. |
1994-03-15 |
2023-08-12 |
Not clear |
| Z W Zhang, S Vijayaraghavan, D K Ber. Neuronal acetylcholine receptors that bind alpha-bungarotoxin with high affinity function as ligand-gated ion channels. Neuron. vol 12. issue 1. 1994-03-01. PMID:7507338. |
using rapid application of agonist, we show here that the native receptors are ligand-gated ion channels which are cation selective, prefer nicotine over acetylcholine, and rapidly desensitize. |
1994-03-01 |
2023-08-12 |
xenopus_laevis |
| R L Hakan, C Hart, C Ey. Specific neurophysiological effects of systemic nicotine on neurons in the nucleus accumbens. Synapse (New York, N.Y.). vol 15. issue 3. 1994-02-09. PMID:7904087. |
these nicotine inhibitions of fimbria-driven nas action potentials appear to be centrally mediated because they were reversed by subsequent systemic injections of the centrally acting nicotinic acetylcholine (nach) antagonist, mecamylamine (1.0 mg/kg, s.c., n = 6) but not by the peripherally acting nach antagonist, hexamethonium (2.0 mg/kg, s.c., n = 6). |
1994-02-09 |
2023-08-12 |
rat |
| M Hu, N L Whiting Theobald, P D Gardne. Nerve growth factor increases the transcriptional activity of the rat neuronal nicotinic acetylcholine receptor beta 4 subunit promoter in transfected PC12 cells. Journal of neurochemistry. vol 62. issue 1. 1994-01-24. PMID:7505316. |
neuronal nicotine acetylcholine receptors play a key role in synaptic transmission in the nervous system. |
1994-01-24 |
2023-08-12 |
rat |
| Y Satoh, Y Habara, T Kanno, K On. Carbamylcholine-induced morphological changes and spatial dynamics of [Ca2+]c in Harderian glands of guinea pigs: calcium-dependent lipid secretion and contraction of myoepithelial cells. Cell and tissue research. vol 274. issue 1. 1993-12-29. PMID:8242700. |
nicotine and catecholamines had no effect on the secretion or on the dynamics of [ca2+]c. it can be concluded that acetylcholine elicits exocytosis in glandular cells and contraction of the myoepithelial cells of harderian glands, accompanied by an increase in [ca2+]c. the dynamics of [ca2+]c of the gland alveoli are mostly dependent on extracellular ca2+. |
1993-12-29 |
2023-08-12 |
Not clear |
| K Lee, A Sekin. Effects of hypoxia on stimulus-release coupling mechanisms in cultured bovine adrenal chromaffin cells. Naunyn-Schmiedeberg's archives of pharmacology. vol 348. issue 3. 1993-12-21. PMID:8232605. |
cells were stimulated with either nicotine (activating nicotinic acetylcholine (ach) receptors) or a high k+ concentration (55 mmol/l kcl; directly activating voltage-dependent ca2+ channels). |
1993-12-21 |
2023-08-12 |
cattle |
| S Miwa, K Lee, S Narumiy. Pharmacological properties of nicotinic acetylcholine receptors on adrenal chromaffin cells and their modification by hypoxic exposure. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology. vol 13. issue 3. 1993-12-17. PMID:8237127. |
to characterize the properties of nicotinic acetylcholine receptors (nachrs) in autonomic ganglia, we examined specific l-[3h]nicotine binding to membrane fraction prepared from cultured bovine adrenal chromaffin cells, using a modified filtration method. |
1993-12-17 |
2023-08-12 |
cattle |
| H Sasaki, K Meguro, Y Matsuzaki, C Doi, S Yamaguchi, T Nakamura, T Aoki, K Sekizawa, Y Shimiz. Effect of nicotine on cognitive disturbance in animals with acetylcholine deficient brain. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology. vol 13. issue 3. 1993-12-17. PMID:8237129. |
effect of nicotine on cognitive disturbance in animals with acetylcholine deficient brain. |
1993-12-17 |
2023-08-12 |
mouse |
| H Sasaki, K Meguro, Y Matsuzaki, C Doi, S Yamaguchi, T Nakamura, T Aoki, K Sekizawa, Y Shimiz. Effect of nicotine on cognitive disturbance in animals with acetylcholine deficient brain. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology. vol 13. issue 3. 1993-12-17. PMID:8237129. |
we therefore suggest that acetylcholine contributes to learning and that nicotine may improve learning in an acetylcholine deprived rats. |
1993-12-17 |
2023-08-12 |
mouse |
| H C Kinney, T J O'Donnell, P Kriger, W F Whit. Early developmental changes in [3H]nicotine binding in the human brainstem. Neuroscience. vol 55. issue 4. 1993-12-02. PMID:8232902. |
based upon the high levels of [3h]nicotine binding at midgestation, combined with experimental data demonstrating trophic properties for acetylcholine, we postulate that nachrs a role in the development of the brainstem tegmentum during this period, and that once this role is fulfilled, nicotinic cholinergic binding decreases and remains low thereafter. |
1993-12-02 |
2023-08-12 |
human |
| V Nassar-Gentina, C Bonansco, M Luxor. Ionic components of the electrical response of chromaffin cells from the toad (Caudiverbera caudiverbera) adrenal gland. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 105. issue 3. 1993-11-26. PMID:7900970. |
as expected, acetylcholine (ach) and nicotine depolarized the cells, though they did not always elicit electrical activity. |
1993-11-26 |
2023-08-12 |
cattle |
| M Shinkai, I Takayanag. Effect of tachykinins on the acetylcholine output stimulated by nicotine from guinea-pig bladder. Regulatory peptides. vol 46. issue 1-2. 1993-10-28. PMID:7692547. |
effect of tachykinins on the acetylcholine output stimulated by nicotine from guinea-pig bladder. |
1993-10-28 |
2023-08-12 |
Not clear |
| M Shinkai, I Takayanag. Effect of tachykinins on the acetylcholine output stimulated by nicotine from guinea-pig bladder. Regulatory peptides. vol 46. issue 1-2. 1993-10-28. PMID:7692547. |
effects of tachykinins on contractile responses and acetylcholine release evoked by nicotine were determined by isotonic transducer and radioimmunoassay. |
1993-10-28 |
2023-08-12 |
Not clear |
| M Shinkai, I Takayanag. Effect of tachykinins on the acetylcholine output stimulated by nicotine from guinea-pig bladder. Regulatory peptides. vol 46. issue 1-2. 1993-10-28. PMID:7692547. |
a sympathetic nerve blocker guanethidine and tachykinin antagonist, [d-arg1,d-pro2,d-trp7,9,leu11]-substance p (rpwwl-sp) partially inhibited the acetylcholine release evoked by nicotine to much the same degree. |
1993-10-28 |
2023-08-12 |
Not clear |
| M Shinkai, I Takayanag. Effect of tachykinins on the acetylcholine output stimulated by nicotine from guinea-pig bladder. Regulatory peptides. vol 46. issue 1-2. 1993-10-28. PMID:7692547. |
in the presence of guanethidine, an acetylcholine output by nicotine was facilitated in the presence of neurokinin a (10 nm) but not sp methyl ester (10 nm) or senktide (10 nm). |
1993-10-28 |
2023-08-12 |
Not clear |
| M Shinkai, I Takayanag. Effect of tachykinins on the acetylcholine output stimulated by nicotine from guinea-pig bladder. Regulatory peptides. vol 46. issue 1-2. 1993-10-28. PMID:7692547. |
these results indicate that acetylcholine release evoked by nicotine is increased by the coordinated action of sympathetic nerves and tachykinins. |
1993-10-28 |
2023-08-12 |
Not clear |
| N Sakuma, N Nagasaka, K Morita, T Dohi, A Tsujimot. Adrenal catecholamine secretory responses in young and adult dogs. Archives internationales de pharmacodynamie et de therapie. vol 322. 1993-10-28. PMID:8105763. |
in the isolated perfused adrenal gland, acetylcholine, nicotine, muscarine (10(-6)-10(-4) m) and high k+ (15-45 mm) enhanced catecholamine release. |
1993-10-28 |
2023-08-12 |
Not clear |
| A V Terry, J J Buccafusco, W J Jackso. Scopolamine reversal of nicotine enhanced delayed matching-to-sample performance in monkeys. Pharmacology, biochemistry, and behavior. vol 45. issue 4. 1993-10-26. PMID:8415832. |
the results of this study are consistent with the hypothesis that the enhanced cognitive performance associated with nicotine is due to central acetylcholine release and subsequent muscarinic receptor stimulation. |
1993-10-26 |
2023-08-12 |
monkey |
| M Morales, C Sierra, A Vidal, J del Castillo, D S Smit. Pharmacological sensitivity of the articular capsule of the primary spines of Eucidaris tribuloides. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 105. issue 1. 1993-09-02. PMID:8101790. |
carbamylcholine (cch), methacholine (meach), nicotine, and muscarine exert a stiffening effect similar to that of acetylcholine (ach), although the time course of their actions varies widely. |
1993-09-02 |
2023-08-12 |
Not clear |