| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Xian, J S Coggan, S R Knoper, D L Kreule. The muscarinic receptor agonist oxotremorine methiodide evokes a nicotinic response in mammalian sympathetic neurons. European journal of pharmacology. vol 259. issue 1. 1994-12-01. PMID:7957589. |
the fast inward transients were similar to responses evoked by the nicotinic receptor agonists acetylcholine, nicotine and 1,1-dimethyl-4-phenyl-piperazinium iodide and were not antagonized by atropine. |
1994-12-01 |
2023-08-12 |
Not clear |
| X Peng, V Gerzanich, R Anand, P J Whiting, J Lindstro. Nicotine-induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover. Molecular pharmacology. vol 46. issue 3. 1994-11-10. PMID:7935334. |
acetylcholine receptors of the same (alpha 4)2(beta 2)3 subunit composition as the predominant subtype of brain nicotinic receptors with high affinity for nicotine have been expressed in xenopus oocytes and in a permanently transfected fibroblast cell line. |
1994-11-10 |
2023-08-12 |
xenopus_laevis |
| R Quirion, J Richard, A Wilso. Muscarinic and nicotinic modulation of cortical acetylcholine release monitored by in vivo microdialysis in freely moving adult rats. Synapse (New York, N.Y.). vol 17. issue 2. 1994-10-17. PMID:8091306. |
peripheral and central injections of nicotine also induced the in vivo release of acetylcholine in the rat cortex, albeit with a lower potency and shorter duration of action than muscarinic antagonists. |
1994-10-17 |
2023-08-12 |
rat |
| R Quirion, J Richard, A Wilso. Muscarinic and nicotinic modulation of cortical acetylcholine release monitored by in vivo microdialysis in freely moving adult rats. Synapse (New York, N.Y.). vol 17. issue 2. 1994-10-17. PMID:8091306. |
interestingly, the combination of a muscarinic antagonist, such as atropine, af-dx 116, or af-dx384, in the presence of nicotine, induced tremendous releases of cortical acetylcholine up to 8- to 10-fold over basal values. |
1994-10-17 |
2023-08-12 |
rat |
| D Bertrand, M Ballivet, M Gomez, S Bertrand, B Phannavong, E D Gundelfinge. Physiological properties of neuronal nicotinic receptors reconstituted from the vertebrate beta 2 subunit and Drosophila alpha subunits. The European journal of neuroscience. vol 6. issue 5. 1994-10-03. PMID:8075828. |
the als/beta 2 and d alpha 2/beta 2 receptors are highly sensitive to acetylcholine and nicotine, and their physiological properties resemble those of native or reconstituted receptors from vertebrates. |
1994-10-03 |
2023-08-12 |
chicken |
| D Bertrand, M Ballivet, M Gomez, S Bertrand, B Phannavong, E D Gundelfinge. Physiological properties of neuronal nicotinic receptors reconstituted from the vertebrate beta 2 subunit and Drosophila alpha subunits. The European journal of neuroscience. vol 6. issue 5. 1994-10-03. PMID:8075828. |
these results demonstrate that the drosophila als and d alpha 2 cdnas encode neuronal nicotinic subunits responding to physiological concentrations of the agonists acetylcholine and nicotine. |
1994-10-03 |
2023-08-12 |
chicken |
| S Jinno, X Y Hua, T L Yaks. Nicotine and acetylcholine induce release of calcitonin gene-related peptide from rat trachea. Journal of applied physiology (Bethesda, Md. : 1985). vol 76. issue 4. 1994-08-30. PMID:8045845. |
nicotine and acetylcholine induce release of calcitonin gene-related peptide from rat trachea. |
1994-08-30 |
2023-08-12 |
rat |
| S Jinno, X Y Hua, T L Yaks. Nicotine and acetylcholine induce release of calcitonin gene-related peptide from rat trachea. Journal of applied physiology (Bethesda, Md. : 1985). vol 76. issue 4. 1994-08-30. PMID:8045845. |
in the present study, we observed that nicotine, the nicotinic analogue cytisine, and acetylcholine (ach) evoked a concentration-dependent (5 x 10(-6)-5 x 10(-5) m) release of calcitonin gene-related peptide (cgrp) from the rat trachea. |
1994-08-30 |
2023-08-12 |
rat |
| C Erostegui, C H Norris, R P Bobbi. In vitro pharmacologic characterization of a cholinergic receptor on outer hair cells. Hearing research. vol 74. issue 1-2. 1994-08-24. PMID:8040084. |
when tested at 100 microm, several agonists also induced outward current responses (acetylcholine > suberyldicholine > or = carbachol > dmpp) whereas nicotine, cytisine and muscarine did not. |
1994-08-24 |
2023-08-12 |
Not clear |
| L M Ren, T Nakane, S Chib. Differential effects of omega-conotoxin GVIA and tetrodotoxin on vasoconstrictions evoked by electrical stimulation and nicotinic receptor stimulation in canine isolated, perfused splenic arteries. British journal of pharmacology. vol 111. issue 4. 1994-08-17. PMID:7913375. |
the effects of omega-conotoxin gvia (omega-cgtx) and tetrodotoxin (ttx) on vasoconstrictions induced by acetylcholine (ach) and nicotine were investigated and compared with those induced by periarterial electrical stimulation in the isolated and perfused canine splenic arteries. |
1994-08-17 |
2023-08-12 |
Not clear |
| I M Khan, T L Yaksh, P Taylo. Ligand specificity of nicotinic acetylcholine receptors in rat spinal cord: studies with nicotine and cytisine. The Journal of pharmacology and experimental therapeutics. vol 270. issue 1. 1994-08-15. PMID:8035312. |
ligand specificity of nicotinic acetylcholine receptors in rat spinal cord: studies with nicotine and cytisine. |
1994-08-15 |
2023-08-12 |
rat |
| Y Kitano, M Makino, C Usui, K Takasuna, Y Kasai, M Hirohashi, K Tamura, S Takayama, H Kojima, H Iizuk. General pharmacological profile of the new cognition-enhancing agent nefiracetam. Arzneimittel-Forschung. vol 44. issue 2A. 1994-07-27. PMID:8018090. |
isolated smooth muscle: nefiracetam had no effect on the resting tonus of isolated ileum, whereas it inhibited the contractile response to acetylcholine, histamine, serotonin, nicotine and bacl2 at higher concentrations (guinea pigs). |
1994-07-27 |
2023-08-12 |
mouse |
| H el-Bizri, P B Clark. Blockade of nicotinic receptor-mediated release of dopamine from striatal synaptosomes by chlorisondamine and other nicotinic antagonists administered in vitro. British journal of pharmacology. vol 111. issue 2. 1994-07-19. PMID:8004384. |
the actions of nicotine, acetylcholine and cytisine were largely dependent on external ca2+. |
1994-07-19 |
2023-08-12 |
rat |
| Z J Yu, L Wecke. Chronic nicotine administration differentially affects neurotransmitter release from rat striatal slices. Journal of neurochemistry. vol 63. issue 1. 1994-07-11. PMID:7911509. |
the objective of these experiments was to determine whether the chronic administration of nicotine, at a dose regimen that increases the density of nicotine binding sites, alters the nicotine-induced release of [3h]-dopamine ([3h]da), [3h]norepinephrine ([3h]ne), [3h]-serotonin ([3h]5-ht), or [3h]acetylcholine ([3h]ach) from rat striatal slices. |
1994-07-11 |
2023-08-12 |
rat |
| P S Chowdhury, X Guo, T D Wakade, D A Przywara, A R Wakad. Exocytosis from a single rat chromaffin cell by cholinergic and peptidergic neurotransmitters. Neuroscience. vol 59. issue 1. 1994-06-23. PMID:7910672. |
we demonstrate that acetylcholine, nicotine, muscarine, vip and pacap are each able to evoke catecholamine secretion from a single chromaffin cell. |
1994-06-23 |
2023-08-12 |
rat |
| P S Chowdhury, X Guo, T D Wakade, D A Przywara, A R Wakad. Exocytosis from a single rat chromaffin cell by cholinergic and peptidergic neurotransmitters. Neuroscience. vol 59. issue 1. 1994-06-23. PMID:7910672. |
nicotine produced an immediate response which usually ended within 10 s. the secretory pattern following acetylcholine appeared to be the sum of the nicotinic and muscarinic patterns, showing both rapid onset and longer duration. |
1994-06-23 |
2023-08-12 |
rat |
| D V Priola, X Cao, D C Smit. Modulation of autonomic responses in normal and denervated isolated canine atria by substance P. The American journal of physiology. vol 266. issue 4 Pt 2. 1994-06-10. PMID:7514360. |
inotropic responses to direct muscarinic stimulation were obtained with 1 x 10(-9) to 1 x 10(-8) m acetylcholine (ach), and responses to stimulation of the intramyocardial intrinsic cardiac nerves (icn) were produced with nicotine (nic), 1.0-10 x 10(-6) m. the same drugs were tested in the presence of 1 x 10(-6) m sp, which had no significant inotropic effects of its own. |
1994-06-10 |
2023-08-12 |
Not clear |
| G Bicker, S Kreiss. Calcium imaging reveals nicotinic acetylcholine receptors on cultured mushroom body neurons. Journal of neurophysiology. vol 71. issue 2. 1994-06-09. PMID:8176442. |
application of acetylcholine (ach) or nicotine, but not pilocarpine, promoted a calcium influx into the cell body and neurites. |
1994-06-09 |
2023-08-12 |
Not clear |
| P V Kostetskiĭ, S F Arkhipova, Iu N Utkin, V I Tsetli. [Conserved and variable segments of amino acid sequences in alpha-subunits of nicotinic acetylcholine receptors and alpha-bungarotoxin-binding proteins]. Biokhimiia (Moscow, Russia). vol 59. issue 2. 1994-05-18. PMID:8155780. |
a comparative study has been carried out of homologous amino acid sequences of alpha-subunits of acetylcholine receptors (achr) and related proteins classified into three groups: (i) alpha-bungarotoxin-binding alpha-subunits of nicotine achr from vertebrate muscles and electrical organ of the skate; (ii) alpha-bungarotoxin-binding alpha-subunits of neuronal achr from chicken and rat brain and (iii) alpha-bungarotoxin-binding alpha-subunit of chicken brain proteins. |
1994-05-18 |
2023-08-12 |
rat |
| A L Favaretto, M M Valença, D L Picanço-Diniz, J A Antunes-Rodrigue. Inhibitory role of cholinergic agonists on testosterone secretion by purified rat Leydig cells. Archives internationales de physiologie, de biochimie et de biophysique. vol 101. issue 6. 1994-05-05. PMID:7511424. |
acetylcholine and carbachol as well as nicotine decreased basal and hcg-induced t secretion. |
1994-05-05 |
2023-08-12 |
rat |