| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J H Hicks, J A Dani, R A Leste. Regulation of the sensitivity of acetylcholine receptors to nicotine in rat habenula neurons. The Journal of physiology. vol 529 Pt 3. 2001-03-01. PMID:11118491. |
regulation of the sensitivity of acetylcholine receptors to nicotine in rat habenula neurons. |
2001-03-01 |
2023-08-12 |
rat |
| R B Free, B W Wenger, D B McKa. Effects of sulfhydryl modification on adrenal nicotinic acetylcholine receptors: disulfide integrity is not essential for activation. Life sciences. vol 68. issue 4. 2001-02-15. PMID:11205888. |
we have found that following dithiothreitol treatment, adrenal chromaffin cells retained the ability to be stimulated by a variety of nicotinic receptor agonists including nicotine, acetylcholine, cytisine, epibatidine, and bromoacetylcholine. |
2001-02-15 |
2023-08-12 |
Not clear |
| B Buisson, Y F Vallejo, W N Green, D Bertran. The unusual nature of epibatidine responses at the alpha4beta2 nicotinic acetylcholine receptor. Neuropharmacology. vol 39. issue 13. 2001-02-08. PMID:11044727. |
fast drug applications obtained with a modified liquid filament system were used for the analyses of the currents evoked by acetylcholine, nicotine and epibatidine. |
2001-02-08 |
2023-08-12 |
rat |
| B Buisson, Y F Vallejo, W N Green, D Bertran. The unusual nature of epibatidine responses at the alpha4beta2 nicotinic acetylcholine receptor. Neuropharmacology. vol 39. issue 13. 2001-02-08. PMID:11044727. |
characterized by a slow onset and offset, epibatidine responses were of smaller amplitude to those evoked by acetylcholine or nicotine. |
2001-02-08 |
2023-08-12 |
rat |
| R Girod, N Barazangi, D McGehee, L W Rol. Facilitation of glutamatergic neurotransmission by presynaptic nicotinic acetylcholine receptors. Neuropharmacology. vol 39. issue 13. 2001-02-08. PMID:11044742. |
the profiles of presynaptic facilitation of glutamate release as elicited by nicotine and acetylcholine were compared in two limbic pathways recapitulated in vitro. |
2001-02-08 |
2023-08-12 |
Not clear |
| M Alkondon, E F Pereira, L E Almeida, W R Randall, E X Albuquerqu. Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus. Neuropharmacology. vol 39. issue 13. 2001-02-08. PMID:11044743. |
nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in ca1 interneurons of rat hippocampus. |
2001-02-08 |
2023-08-12 |
rat |
| M Alkondon, E F Pereira, L E Almeida, W R Randall, E X Albuquerqu. Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus. Neuropharmacology. vol 39. issue 13. 2001-02-08. PMID:11044743. |
behavioral effects of cigarette smoking are attributed to the interactions of nicotine with brain nicotinic acetylcholine receptors (nachrs). |
2001-02-08 |
2023-08-12 |
rat |
| L E Waggoner, K A Dickinson, D S Poole, Y Tabuse, J Miwa, W R Schafe. Long-term nicotine adaptation in Caenorhabditis elegans involves PKC-dependent changes in nicotinic receptor abundance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 23. 2001-02-08. PMID:11102488. |
chronic exposure to nicotine leads to long-term changes in both the abundance and activity of nicotinic acetylcholine receptors, processes thought to contribute to nicotine addiction. |
2001-02-08 |
2023-08-12 |
caenorhabditis_elegans |
| S Pogun, S Demirgoren, D Taskiran, L Kanit, O Yilmaz, E O Koylu, B Balkan, E D Londo. Nicotine modulates nitric oxide in rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 6. 2001-02-08. PMID:11115736. |
nicotine exerts its central actions by regulating cationic fluxes through nicotinic acetylcholine receptors (nachrs). |
2001-02-08 |
2023-08-12 |
rat |
| M I Dama. Influence of gender and sex hormones on nicotine acute pharmacological effects in mice. The Journal of pharmacology and experimental therapeutics. vol 296. issue 1. 2001-02-02. PMID:11123373. |
in addition, progesterone and 17beta-estradiol blocked nicotine activation of alpha(4)beta(2) neuronal acetylcholine nicotinic receptors expressed in oocytes. |
2001-02-02 |
2023-08-12 |
mouse |
| I I Stepanov, N A Lose. Characteristics of cholinoreceptors on identified TAN neurons of the ground snail Achatina fulica. Neuroscience and behavioral physiology. vol 30. issue 5. 2001-01-25. PMID:11037148. |
acetylcholine, nicotine, the selective n-cholinoreceptor agonist suberyldicholine, and the selective n-cholinoreceptor agonist 5-methylfurmethide concentration-dependently inhibited background spike activity to the level of complete blockade at concentrations of 500 microm. |
2001-01-25 |
2023-08-12 |
Not clear |
| C Gotti, E Carbonnelle, M Moretti, R Zwart, F Clement. Drugs selective for nicotinic receptor subtypes: a real possibility or a dream? Behavioural brain research. vol 113. issue 1-2. 2001-01-03. PMID:10942044. |
nicotine exerts a number of different effects on the nervous system by interacting with neuronal nicotinic acetylcholine receptors (nachrs). |
2001-01-03 |
2023-08-12 |
rat |
| M Wang, S Okada, Y Murakami, K Yokotan. Nicotine-induced noradrenaline release from the isolated rat stomach by activation of L- and N-type calcium channels. Japanese journal of pharmacology. vol 83. issue 2. 2000-12-27. PMID:10928321. |
from these results, it was suggested that nicotine activates nicotinic acetylcholine receptors located on the sympathetic ganglia, thereby evoking na release by activation of l-type vacc located on the gastric sympathetic ganglia and n-type vacc probably located on the sympathetic nerve terminals in the rat stomach. |
2000-12-27 |
2023-08-12 |
rat |
| M R Gerasimov, M Franceschi, N D Volkow, O Rice, W K Schiffer, S L Dewe. Synergistic interactions between nicotine and cocaine or methylphenidate depend on the dose of dopamine transporter inhibitor. Synapse (New York, N.Y.). vol 38. issue 4. 2000-12-14. PMID:11044890. |
in contrast, nicotine stimulates acetylcholine receptors located presynaptically on dopaminergic projections from the ventral tegmental area (vta) to the nac and increases da transmission. |
2000-12-14 |
2023-08-12 |
Not clear |
| S S Watkins, G F Koob, A Marko. Neural mechanisms underlying nicotine addiction: acute positive reinforcement and withdrawal. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 2. issue 1. 2000-11-30. PMID:11072438. |
the roles of various neurotransmitter systems, including acetylcholine, dopamine, serotonin, glutamate, gamma-aminobutyric acid, and opioid peptides in acute nicotine reinforcement and withdrawal from chronic administration are examined followed by a discussion of potential neuroadaptations within these neurochemical systems that may lead to the development of nicotine dependence. |
2000-11-30 |
2023-08-12 |
Not clear |
| T Narahashi, C P Fenster, M W Quick, R A Lester, W Marszalec, G L Aistrup, D B Sattelle, B R Martin, E D Levi. Symposium overview: mechanism of action of nicotine on neuronal acetylcholine receptors, from molecule to behavior. Toxicological sciences : an official journal of the Society of Toxicology. vol 57. issue 2. 2000-11-21. PMID:11006350. |
symposium overview: mechanism of action of nicotine on neuronal acetylcholine receptors, from molecule to behavior. |
2000-11-21 |
2023-08-12 |
Not clear |
| T Narahashi, C P Fenster, M W Quick, R A Lester, W Marszalec, G L Aistrup, D B Sattelle, B R Martin, E D Levi. Symposium overview: mechanism of action of nicotine on neuronal acetylcholine receptors, from molecule to behavior. Toxicological sciences : an official journal of the Society of Toxicology. vol 57. issue 2. 2000-11-21. PMID:11006350. |
nicotine has long been known to interact with nicotinic acetylcholine (ach) receptors since langley used it extensively to chart sympathetic ganglia a century ago. |
2000-11-21 |
2023-08-12 |
Not clear |
| J E Slemmer, B R Martin, M I Dama. Bupropion is a nicotinic antagonist. The Journal of pharmacology and experimental therapeutics. vol 295. issue 1. 2000-11-03. PMID:10991997. |
in addition, bupropion blocks nicotine activation of alpha(3)beta(2), alpha(4)beta(2), and alpha(7) neuronal acetylcholine nicotinic receptors (nachrs) with some degree of selectivity. |
2000-11-03 |
2023-08-12 |
Not clear |
| E Carstens, C T Simons, J M Dessirier, M I Carstens, S L Jink. Role of neuronal nicotinic-acetylcholine receptors in the activation of neurons in trigeminal subnucleus caudalis by nicotine delivered to the oral mucosa. Experimental brain research. vol 132. issue 3. 2000-10-19. PMID:10883386. |
to characterize the role of neuronal nicotinic acetylcholine receptors (nachrs) in oral irritation and pain, we employed the method of c-fos immunohistochemistry to map the locations and numbers of brainstem neurons that express the immediate-early gene, c-fos, after application of nicotine to the tongue, either alone or after pretreatment with cholinergic antagonists. |
2000-10-19 |
2023-08-12 |
rat |
| E Quattrocki, A Baird, D Yurgelun-Tod. Biological aspects of the link between smoking and depression. Harvard review of psychiatry. vol 8. issue 3. 2000-10-12. PMID:10973935. |
nicotine binds to nicotinic receptors in the brain, augmenting the release of numerous neurotransmitters, including dopamine, serotonin, norepinephrine, acetylcholine, gamma-aminobutyric acid, and glutamate. |
2000-10-12 |
2023-08-12 |
Not clear |