| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christie D Fowler, Michael A Arends, Paul J Kenn. Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice. Behavioural pharmacology. vol 19. issue 5-6. 2008-12-31. PMID:18690103. |
subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice. |
2008-12-31 |
2023-08-12 |
mouse |
| Anderson Ribeiro-Carvalho, Carla S Lima, Cláudio C Filgueiras, Alex C Manhães, Yael Abreu-Villaç. Nicotine and ethanol interact during adolescence: effects on the central cholinergic systems. Brain research. vol 1232. 2008-12-08. PMID:18692029. |
since nicotine is a cholinergic agonist and it has been shown that ethanol interferes with nicotinic acetylcholine receptors (nachrs), the current work focused on cholinergic systems. |
2008-12-08 |
2023-08-12 |
mouse |
| Taro Kishi, Masashi Ikeda, Tsuyoshi Kitajima, Yoshio Yamanouchi, Yoko Kinoshita, Kunihiro Kawashima, Tomo Okochi, Toshiya Inada, Norio Ozaki, Nakao Iwat. Genetic association analysis of tagging SNPs in alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes (CHRNA4 and CHRNB2) with schizophrenia in the Japanese population. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 10. 2008-12-02. PMID:18762859. |
the majority of high affinity nicotine binding sites in the human brain have been implicated in heteropentameric alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptors; therefore, these two neuronal nicotinic acetylcholine receptors genes (chrna4 and chrnb2) are considered to be attractive candidate genes for the pathophysiology of schizophrenia. |
2008-12-02 |
2023-08-12 |
human |
| Piotr Tutk. Nicotinic receptor partial agonists as novel compounds for the treatment of smoking cessation. Expert opinion on investigational drugs. vol 17. issue 10. 2008-12-02. PMID:18808308. |
nicotine addiction and the neurobiological mechanisms explaining nicotine reinforcement, withdrawal, and relapse involve alpha4beta2 nicotinic acetylcholine receptors (nachrs). |
2008-12-02 |
2023-08-12 |
human |
| Natsuko Kageyama-Yahara, Yoko Suehiro, Takeshi Yamamoto, Makoto Kadowak. IgE-induced degranulation of mucosal mast cells is negatively regulated via nicotinic acetylcholine receptors. Biochemical and biophysical research communications. vol 377. issue 1. 2008-11-28. PMID:18848921. |
pretreatment with non-specific nachrs agonists, acetylcholine, nicotine and epibatidine and a specific alpha7 subunit agonist gts-21 significantly inhibited antigen-induced degranulation of mbmmcs in a dose-dependent manner and gts-21-induced inhibition was significantly blocked by alpha7 subunit antagonist, alpha-bungarotoxin. |
2008-11-28 |
2023-08-12 |
Not clear |
| Theodore A Slotkin, Bethany E Bodwell, Ian T Ryde, Frederic J Seidle. Adolescent nicotine treatment changes the response of acetylcholine systems to subsequent nicotine administration in adulthood. Brain research bulletin. vol 76. issue 1-2. 2008-11-17. PMID:18395624. |
adolescent nicotine treatment changes the response of acetylcholine systems to subsequent nicotine administration in adulthood. |
2008-11-17 |
2023-08-12 |
rat |
| Theodore A Slotkin, Bethany E Bodwell, Ian T Ryde, Frederic J Seidle. Adolescent nicotine treatment changes the response of acetylcholine systems to subsequent nicotine administration in adulthood. Brain research bulletin. vol 76. issue 1-2. 2008-11-17. PMID:18395624. |
nicotine alters the developmental trajectory of acetylcholine (ach) systems in the immature brain, with vulnerability extending from fetal stages through adolescence. |
2008-11-17 |
2023-08-12 |
rat |
| L-Y Lee, Q G. Cough sensors. IV. Nicotinic membrane receptors on cough sensors. Handbook of experimental pharmacology. issue 187. 2008-11-17. PMID:18825337. |
furthermore, both nicotine and acetylcholine can evoke inward current, membrane depolarization, and action potentials in isolated pulmonary sensory neurons, and these responses are blocked by hexamethonium. |
2008-11-17 |
2023-08-12 |
human |
| L-Y Lee, Q G. Cough sensors. IV. Nicotinic membrane receptors on cough sensors. Handbook of experimental pharmacology. issue 187. 2008-11-17. PMID:18825337. |
taken together, these findings suggest that the tussive effect of nicotine is probably mediated through an activation of nicotinic acetylcholine receptors (nachrs) expressed on the sensory terminals of cough receptors located in the airway mucosa. |
2008-11-17 |
2023-08-12 |
human |
| Kelli R Rodvelt, George R Kracke, Todd R Schachtman, Dennis K Mille. Ketamine induces hyperactivity in rats and hypersensitivity to nicotine in rat striatal slices. Pharmacology, biochemistry, and behavior. vol 91. issue 1. 2008-11-06. PMID:18639577. |
these circuits also contain nicotinic acetylcholine receptors that are activated by nicotine. |
2008-11-06 |
2023-08-12 |
rat |
| Kelli R Rodvelt, Todd R Schachtman, George R Kracke, Dennis K Mille. NMDA receptor blockade augmented nicotine-evoked dopamine release from rat prefrontal cortex slices. Neuroscience letters. vol 440. issue 3. 2008-11-05. PMID:18579301. |
nicotine evokes dopamine release through activation of nicotinic acetylcholine receptors, and tobacco cigarette smoking is more prevalent among individuals diagnosed with schizophrenia. |
2008-11-05 |
2023-08-12 |
rat |
| Rifat J Hussain, Olga D Taraschenko, Stanley D Glic. Effects of nicotine, methamphetamine and cocaine on extracellular levels of acetylcholine in the interpeduncular nucleus of rats. Neuroscience letters. vol 440. issue 3. 2008-11-05. PMID:18583043. |
effects of nicotine, methamphetamine and cocaine on extracellular levels of acetylcholine in the interpeduncular nucleus of rats. |
2008-11-05 |
2023-08-12 |
rat |
| Rifat J Hussain, Olga D Taraschenko, Stanley D Glic. Effects of nicotine, methamphetamine and cocaine on extracellular levels of acetylcholine in the interpeduncular nucleus of rats. Neuroscience letters. vol 440. issue 3. 2008-11-05. PMID:18583043. |
in order to determine the effects of cocaine, amphetamine and nicotine on cholinergic neurotransmission in the habenulo-interpeduncular pathway, levels of acetylcholine were assessed during microdialysis in freely moving rats. |
2008-11-05 |
2023-08-12 |
rat |
| Rifat J Hussain, Olga D Taraschenko, Stanley D Glic. Effects of nicotine, methamphetamine and cocaine on extracellular levels of acetylcholine in the interpeduncular nucleus of rats. Neuroscience letters. vol 440. issue 3. 2008-11-05. PMID:18583043. |
nicotine (0.1 and 0.4 mg/kg s.c.) produced a dose-dependent decrease in extracellular levels of acetylcholine, while methamphetamine (1 and 4 mg/kg i.p.) |
2008-11-05 |
2023-08-12 |
rat |
| Chongbo Zhong, Chuang Du, Melissa Hancock, Marjolijn Mertz, David A Talmage, Lorna W Rol. Presynaptic type III neuregulin 1 is required for sustained enhancement of hippocampal transmission by nicotine and for axonal targeting of alpha7 nicotinic acetylcholine receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 37. 2008-11-03. PMID:18784291. |
presynaptic type iii neuregulin 1 is required for sustained enhancement of hippocampal transmission by nicotine and for axonal targeting of alpha7 nicotinic acetylcholine receptors. |
2008-11-03 |
2023-08-12 |
Not clear |
| Naïla Even, Ana Cardona, Martine Soudant, Pierre-Jean Corringer, Jean-Pierre Changeux, Isabelle Cloëz-Tayaran. Regional differential effects of chronic nicotine on brain alpha 4-containing and alpha 6-containing receptors. Neuroreport. vol 19. issue 15. 2008-11-03. PMID:18797314. |
chronic nicotine upregulates central nicotinic acetylcholine receptors (nachrs), a plasticity process thought to contribute to its addictive properties. |
2008-11-03 |
2023-08-12 |
mouse |
| George S Portugal, Thomas J Goul. Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research. Behavioural brain research. vol 193. issue 1. 2008-10-21. PMID:18571741. |
genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research. |
2008-10-21 |
2023-08-12 |
mouse |
| Hisatsugu Miyat. [Role of smoking and nicotine in neuropsychiatric disorders: evidence for therapeutic role of nicotinic acetylcholine receptors]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 28. issue 4. 2008-10-21. PMID:18800618. |
[role of smoking and nicotine in neuropsychiatric disorders: evidence for therapeutic role of nicotinic acetylcholine receptors]. |
2008-10-21 |
2023-08-12 |
Not clear |
| Richard Exley, Michael A Clements, Henrike Hartung, J Michael McIntosh, Stephanie J Crag. Alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 9. 2008-10-08. PMID:18033235. |
alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens. |
2008-10-08 |
2023-08-12 |
mouse |
| Richard Exley, Michael A Clements, Henrike Hartung, J Michael McIntosh, Stephanie J Crag. Alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 9. 2008-10-08. PMID:18033235. |
nicotine, by desensitizing beta2 subunit-containing (beta2*) nicotinic acetylcholine receptors (nachrs) on striatal da axons, significantly enhances how da is released by reward-related burst activity compared to nonreward-related tonic activity. |
2008-10-08 |
2023-08-12 |
mouse |