| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Myung N Kim, Emily M Jutkiewicz, Minjia Zhang, Margaret E Gneg. The sensitizing effect of acute nicotine on amphetamine-stimulated behavior and dopamine efflux requires activation of β2 subunit-containing nicotinic acetylcholine receptors and glutamate N-methyl-D-aspartate receptors. Neuropharmacology. vol 60. issue 7-8. 2012-01-18. PMID:20971124. |
the sensitizing effect of acute nicotine on amphetamine-stimulated behavior and dopamine efflux requires activation of β2 subunit-containing nicotinic acetylcholine receptors and glutamate n-methyl-d-aspartate receptors. |
2012-01-18 |
2023-08-12 |
rat |
| Myung N Kim, Emily M Jutkiewicz, Minjia Zhang, Margaret E Gneg. The sensitizing effect of acute nicotine on amphetamine-stimulated behavior and dopamine efflux requires activation of β2 subunit-containing nicotinic acetylcholine receptors and glutamate N-methyl-D-aspartate receptors. Neuropharmacology. vol 60. issue 7-8. 2012-01-18. PMID:20971124. |
dihydro-β-erythroidine (dhβe), a relatively selective antagonist at β2 subunit-containing (β2∗) nicotinic acetylcholine receptors (nachr), but not methyllycaconitine (mla), a relatively selective antagonist at α7 nachrs, blocked the sensitizing effect of nicotine on amph-stimulated locomotor activity. |
2012-01-18 |
2023-08-12 |
rat |
| Kelly P Cosgrove, Irina Esterlis, Graeme F Mason, Frederic Bois, Stephanie S O'Malley, John H Krysta. Neuroimaging insights into the role of cortical GABA systems and the influence of nicotine on the recovery from alcohol dependence. Neuropharmacology. vol 60. issue 7-8. 2012-01-18. PMID:21276806. |
second, we discuss preclinical evidence that suggests nicotine affects gaba neuronal function indirectly by a primary action at neuronal nicotinic acetylcholine receptors. |
2012-01-18 |
2023-08-12 |
Not clear |
| Antonio Rodriguez-Gaztelumendi, Malin Alvehus, Therése Andersson, Stig O P Jacobsso. Comparison of the effects of nicotine upon the transcellular electrical resistance and sucrose permeability of human ECV304/rat C6 co-cultures and human CaCo₂ cells. Toxicology letters. vol 207. issue 1. 2012-01-18. PMID:21889975. |
it is concluded that in contrast to the situation for the bbb, ecv304 cells lack nicotinic acetylcholine receptors and the barrier properties of ecv304/c6 co-cultures are not affected to any important extent by nicotine. |
2012-01-18 |
2023-08-12 |
human |
| Lili Guo, Zhihao Wu, Qinghua Zho. [Roles of nicotine and nicotinic acetylcholine receptors (nAChR) in carcinogenesis and development of lung cancer]. Zhongguo fei ai za zhi = Chinese journal of lung cancer. vol 14. issue 9. 2012-01-16. PMID:21924045. |
[roles of nicotine and nicotinic acetylcholine receptors (nachr) in carcinogenesis and development of lung cancer]. |
2012-01-16 |
2023-08-12 |
Not clear |
| Rita Machaalani, Meichien Say, Karen A Water. Effects of cigarette smoke exposure on nicotinic acetylcholine receptor subunits α7 and β2 in the sudden infant death syndrome (SIDS) brainstem. Toxicology and applied pharmacology. vol 257. issue 3. 2012-01-13. PMID:22000980. |
it is postulated that nicotine, as the main neurotoxic constituent of cigarette smoke, influences sids risk through effects on nicotinic acetylcholine receptors (nachrs) in brainstem nuclei that control respiration and arousal. |
2012-01-13 |
2023-08-12 |
Not clear |
| Pingxing Xie, Henry R Kranzler, Michael Krauthammer, Kelly P Cosgrove, David Oslin, Raymond F Anton, Lindsay A Farrer, Marina R Picciotto, John H Krystal, Hongyu Zhao, Joel Gelernte. Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence. Biological psychiatry. vol 70. issue 6. 2012-01-09. PMID:21683344. |
several studies report association of alpha-4 nicotinic acetylcholine receptors (encoded by chrna4) with nicotine dependence (nd). |
2012-01-09 |
2023-08-12 |
Not clear |
| Makiko Maeda, Yasushi Fujio, Junichi Azum. [Genetic analysis for nicotine dependence]. Nihon rinsho. Japanese journal of clinical medicine. vol 69. issue 10. 2011-12-16. PMID:22073590. |
on the other, the nicotine acts in the brain through neuronal nicotinic acetylcholine receptors (nachrs), which regulate the addictive properties of nicotine. |
2011-12-16 |
2023-08-12 |
Not clear |
| Min Yu, Qian Liu, Jing Sun, Kaihong Yi, Libiao Wu, Xuerui Ta. Nicotine improves the functional activity of late endothelial progenitor cells via nicotinic acetylcholine receptors. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 89. issue 4. 2011-12-12. PMID:21774635. |
nicotine improves the functional activity of late endothelial progenitor cells via nicotinic acetylcholine receptors. |
2011-12-12 |
2023-08-12 |
human |
| Min Yu, Qian Liu, Jing Sun, Kaihong Yi, Libiao Wu, Xuerui Ta. Nicotine improves the functional activity of late endothelial progenitor cells via nicotinic acetylcholine receptors. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 89. issue 4. 2011-12-12. PMID:21774635. |
the aim of this study is to investigate whether nicotinic acetylcholine receptors (nachrs) are involved in the modulation of functional activity of late endothelial progenitor cells (epcs) induced by nicotine. |
2011-12-12 |
2023-08-12 |
human |
| H Kawasaki, S Takatori, Y Zamami, T Koyama, M Goda, K Hirai, P Tangsucharit, X Jin, N Hobara, Y Kitamur. Paracrine control of mesenteric perivascular axo-axonal interaction. Acta physiologica (Oxford, England). vol 203. issue 1. 2011-12-07. PMID:20887357. |
in rat perfused mesenteric vascular beds without endothelium and with active tone, perfusion of nicotine, or bolus injection of capsaicin and acetylcholine and periarterial nerve stimulation (pns) lowered ph levels of out flowed perfusate concomitant with vasodilation. |
2011-12-07 |
2023-08-12 |
rat |
| H Kawasaki, S Takatori, Y Zamami, T Koyama, M Goda, K Hirai, P Tangsucharit, X Jin, N Hobara, Y Kitamur. Paracrine control of mesenteric perivascular axo-axonal interaction. Acta physiologica (Oxford, England). vol 203. issue 1. 2011-12-07. PMID:20887357. |
a study using a fluorescent ph indicator demonstrated that nicotine, acetylcholine and capsaicin applied outside small mesenteric artery lowered perivascular ph levels, which were not observed in ca(2+) free medium. |
2011-12-07 |
2023-08-12 |
rat |
| Julia Radosa, Wilhelm Dyck, Sergij Goerdt, Hjalmar Kurze. The cholinergic system in guttate psoriasis with special reference to mast cells. Experimental dermatology. vol 20. issue 8. 2011-12-06. PMID:21521372. |
in vitro, acetylcholine, choline and nicotine, but not muscarine, induced mast cell degranulation but not ltb-4 or tnf-alpha secretion. |
2011-12-06 |
2023-08-12 |
Not clear |
| Masashi Yasuda, Ryoji Kawahara, Hiroshi Hashimura, Naoki Yamanaka, Maho Iimori, Kikuko Amagase, Shinichi Kato, Koji Takeuch. Dopamine D₂-receptor antagonists ameliorate indomethacin-induced small intestinal ulceration in mice by activating α7 nicotinic acetylcholine receptors. Journal of pharmacological sciences. vol 116. issue 3. 2011-12-06. PMID:21691039. |
we have reported that nicotine and the specific α7achr agonist ameliorate indomethacin-induced intestinal lesions in mice by activating α7 nicotinic acetylcholine receptors (α7nachr). |
2011-12-06 |
2023-08-12 |
mouse |
| S K Brandt, M E Weatherly, L Ware, D M Linn, C L Lin. Calcium preconditioning triggers neuroprotection in retinal ganglion cells. Neuroscience. vol 172. 2011-12-05. PMID:21044663. |
previous studies from this lab [wehrwein e, thompson sa, coulibaly sf, linn dm, linn cl (2004) invest ophthalmol vis sci 45:1531-1543] have demonstrated that acetylcholine (ach) and nicotine protects against glutamate-induced excitotoxicity in isolated adult pig rgcs through nicotinic acetylcholine receptors (nachrs). |
2011-12-05 |
2023-08-12 |
Not clear |
| Jade J Bito-Onon, Jeffrey A Simms, Susmita Chatterjee, Joan Holgate, Selena E Bartlet. Varenicline, a partial agonist at neuronal nicotinic acetylcholine receptors, reduces nicotine-induced increases in 20% ethanol operant self-administration in Sprague-Dawley rats. Addiction biology. vol 16. issue 3. 2011-12-02. PMID:21392178. |
both nicotine and ethanol have been shown to interact with neuronal nicotinic acetylcholine receptors (nachrs), suggesting these receptors are a common biological target for the effects of nicotine and ethanol in the brain. |
2011-12-02 |
2023-08-12 |
rat |
| Pei-Wen Cheng, Pei-Jung Lu, Siang-Ru Chen, Wen-Yu Ho, Wen-Han Cheng, Ling-Zong Hong, Tung-Chen Yeh, Gwo-Ching Sun, Ling-Lin Wang, Michael Hsiao, Ching-Jiunn Tsen. Central nicotinic acetylcholine receptor involved in Ca(2+) -calmodulin-endothelial nitric oxide synthase pathway modulated hypotensive effects. British journal of pharmacology. vol 163. issue 6. 2011-11-15. PMID:21091651. |
recent evidence has suggested that nicotine decreases blood pressure (bp) and heart rate (hr) in the nucleus tractus solitarii (nts), indicating that nicotinic acetylcholine receptors (nachrs) play an important role in bp control in the nts. |
2011-11-15 |
2023-08-12 |
Not clear |
| Chia-Hwa Lee, Chih-Hsiung Wu, Yuan-Soon H. From smoking to cancers: novel targets to neuronal nicotinic acetylcholine receptors. Journal of oncology. vol 2011. 2011-11-10. PMID:21772846. |
nicotine and its specific metabolized carcinogens directly bind to nicotinic acetylcholine receptors (nachrs) on cell membranes and trigger the nachr signal cascade. |
2011-11-10 |
2023-08-12 |
Not clear |
| Angela Alama, Cristina Bruzzo, Zita Cavalieri, Alessandra Forlani, Yuri Utkin, Ida Casciano, Massimo Roman. Inhibition of the nicotinic acetylcholine receptors by cobra venom α-neurotoxins: is there a perspective in lung cancer treatment? PloS one. vol 6. issue 6. 2011-11-02. PMID:21695184. |
nicotine exerts its oncogenic effects through the binding to nicotinic acetylcholine receptors (nachrs) and the activation of downstream pathways that block apoptosis and promote neo-angiogenesis. |
2011-11-02 |
2023-08-12 |
mouse |
| Ermelinda Lomazzo, Gregory P Hussmann, Barry B Wolfe, Robert P Yasuda, David C Perry, Kenneth J Kella. Effects of chronic nicotine on heteromeric neuronal nicotinic receptors in rat primary cultured neurons. Journal of neurochemistry. vol 119. issue 1. 2011-10-31. PMID:21806615. |
nicotine increases the number of neuronal nicotinic acetylcholine receptors (nachrs) in brain. |
2011-10-31 |
2023-08-12 |
rat |