| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rogier B Poorthuis, Huibert D Mansvelde. Nicotinic acetylcholine receptors controlling attention: behavior, circuits and sensitivity to disruption by nicotine. Biochemical pharmacology. vol 86. issue 8. 2013-12-17. PMID:23856288. |
nicotinic acetylcholine receptors controlling attention: behavior, circuits and sensitivity to disruption by nicotine. |
2013-12-17 |
2023-08-12 |
Not clear |
| Jared W Young, Mark A Geye. Evaluating the role of the alpha-7 nicotinic acetylcholine receptor in the pathophysiology and treatment of schizophrenia. Biochemical pharmacology. vol 86. issue 8. 2013-12-17. PMID:23856289. |
while nicotine acts on multiple nicotinic acetylcholine receptors (nachrs), the primary target of research is often the homomeric α7 nachr. |
2013-12-17 |
2023-08-12 |
Not clear |
| William M Doyon, Alyse M Thomas, Alexey Ostroumov, Yu Dong, John A Dan. Potential substrates for nicotine and alcohol interactions: a focus on the mesocorticolimbic dopamine system. Biochemical pharmacology. vol 86. issue 8. 2013-12-17. PMID:23876345. |
while nicotine primarily acts via nicotinic acetylcholine receptors, alcohol acts upon a wider range of receptors and molecular substrates. |
2013-12-17 |
2023-08-12 |
Not clear |
| Gaurav Jain, Edgar A Jaime. Nicotine signaling and progression of chronic kidney disease in smokers. Biochemical pharmacology. vol 86. issue 8. 2013-12-17. PMID:23892062. |
nicotine, in addition to its role in the addictive properties of cigarette smoking, has other biological effects via activation of non-neuronal nicotinic acetylcholine receptors (nachrs). |
2013-12-17 |
2023-08-12 |
human |
| Jie Wu, Ming Gao, Jian-Xin Shen, Wei-Xing Shi, Andrew M Oster, Boris S Gutki. Cortical control of VTA function and influence on nicotine reward. Biochemical pharmacology. vol 86. issue 8. 2013-12-17. PMID:23933294. |
nicotine acts on widely distributed nicotinic acetylcholine receptors (nachrs) in the brain and excites dopamine (da) neurons in the ventral tegmental area (vta). |
2013-12-17 |
2023-08-12 |
Not clear |
| S de la Salle, D Smith, J Choueiry, D Impey, T Philippe, H Dort, A Millar, P Albert, V Knot. Effects of COMT genotype on sensory gating and its modulation by nicotine: Differences in low and high P50 suppressors. Neuroscience. vol 241. 2013-12-12. PMID:23535252. |
elevated smoking rates seen in schizophrenia populations may be an attempt to correct neuropathologies associated with deficient nicotinic acetylcholine receptors and/or dopaminergic systems using exogenous nicotine. |
2013-12-12 |
2023-08-12 |
Not clear |
| Staci E Engle, Pei-Yu Shih, J Michael McIntosh, Ryan M Drena. α4α6β2* nicotinic acetylcholine receptor activation on ventral tegmental area dopamine neurons is sufficient to stimulate a depolarizing conductance and enhance surface AMPA receptor function. Molecular pharmacology. vol 84. issue 3. 2013-11-26. PMID:23788655. |
nicotine activates and/or desensitizes nicotinic acetylcholine receptors (nachrs) throughout the brain. |
2013-11-26 |
2023-08-12 |
mouse |
| Emily M Jutkiewicz, Kenner C Rice, F Ivy Carroll, James H Wood. Patterns of nicotinic receptor antagonism II: cardiovascular effects in rats. Drug and alcohol dependence. vol 131. issue 3. 2013-11-18. PMID:23333294. |
considering nicotinic acetylcholine receptors mediate critical peripheral effects of acetylcholine, such as cardiovascular effects, it is important to study how nicotinic antagonists would alter the cardiovascular system and the cardiovascular changes induced by nicotine. |
2013-11-18 |
2023-08-12 |
rat |
| Richard A Stone, Machelle T Pardue, P Michael Iuvone, Tejvir S Khuran. Pharmacology of myopia and potential role for intrinsic retinal circadian rhythms. Experimental eye research. vol 114. 2013-10-30. PMID:23313151. |
recent research implicates a potential role of nicotinic acetylcholine receptors; and the refractive effects in population surveys of passive exposure to cigarette smoke, of which nicotine is a constituent, support clinical relevance. |
2013-10-30 |
2023-08-12 |
Not clear |
| Jacco J de Haan, M'hamed Hadfoune, Tim Lubbers, Caroline Hodin, Kaatje Lenaerts, Akihiko Ito, Isabelle Verbaeys, Michael J Skynner, Cathy Cailotto, Jan van der Vliet, Wouter J de Jonge, Jan-Willem M Greve, Wim A Buurma. Lipid-rich enteral nutrition regulates mucosal mast cell activation via the vagal anti-inflammatory reflex. American journal of physiology. Gastrointestinal and liver physiology. vol 305. issue 5. 2013-10-28. PMID:23812038. |
accordingly, release of β-hexosaminidase by mc/9 mast cells following lps or ige-ovalbumin complexes was dose dependently inhibited by acetylcholine and nicotine. |
2013-10-28 |
2023-08-12 |
mouse |
| Derek S Wilkinson, Thomas J Goul. Withdrawal from chronic nicotine and subsequent sensitivity to nicotine challenge on contextual learning. Behavioural brain research. vol 250. 2013-10-25. PMID:23660650. |
theories of nicotine withdrawal suggest that nicotinic acetylcholine receptors (nachrs) are hypersensitive during withdrawal, which suggests enhanced sensitivity to nicotine challenge. |
2013-10-25 |
2023-08-12 |
mouse |
| H M Kamens, R P Corley, M B McQueen, M C Stallings, C J Hopfer, T J Crowley, S A Brown, J K Hewitt, M A Ehringe. Nominal association with CHRNA4 variants and nicotine dependence. Genes, brain, and behavior. vol 12. issue 3. 2013-09-23. PMID:23350800. |
nicotine binds to nicotinic acetylcholine receptors and studies in animal models have shown that α4β2 receptors mediate many behavioral effects of nicotine. |
2013-09-23 |
2023-08-12 |
human |
| K Iwamoto, D Mata, D M Linn, C L Lin. Neuroprotection of rat retinal ganglion cells mediated through alpha7 nicotinic acetylcholine receptors. Neuroscience. vol 237. 2013-09-23. PMID:23402849. |
in this study, neuroprotection against glutamate-induced excitotoxicity was analyzed using acetylcholine (ach), nicotine and the α7 specific nicotinic acetylcholine receptor (α7 nachr) agonist, n-[(3r)-1-azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride (pnu-282987), in cultured adult rat retinal neurons. |
2013-09-23 |
2023-08-12 |
rat |
| Zheman Xiao, Fan Zhu, Zuneng Lu, Songqing Pan, Jingjing Liang, Jiangquan Zheng, Zhongchun Li. Modulation of nicotinic acetylcholine receptors in native sympathetic neurons by ethanol. International journal of physiology, pathophysiology and pharmacology. vol 5. issue 3. 2013-09-17. PMID:24044035. |
to determine whether actions on nicotine acetylcholine receptors (nachrs) contribute to ethanol's depressant effects on the autonomic nervous system. |
2013-09-17 |
2023-08-12 |
Not clear |
| David Pubill, Sara Garcia-Ratés, Jordi Camarasa, Elena Escubed. 3,4-Methylenedioxy-methamphetamine induces in vivo regional up-regulation of central nicotinic receptors in rats and potentiates the regulatory effects of nicotine on these receptors. Neurotoxicology. vol 35. 2013-09-10. PMID:23261423. |
nicotine (nic), the main psychostimulant compound of smoked tobacco, exerts its effects through activation of central nicotinic acetylcholine receptors (nachr), which become up-regulated after chronic administration. |
2013-09-10 |
2023-08-12 |
rat |
| Junwei Hao, Fu-Dong Shi, Mohammed Abdelwahab, Samuel X Shi, Alain Simard, Paul Whiteaker, Ronald Lukas, Qinghua Zho. Nicotinic receptor β2 determines NK cell-dependent metastasis in a murine model of metastatic lung cancer. PloS one. vol 8. issue 2. 2013-09-10. PMID:23469004. |
nicotine is a psychoactive component of tobacco products that acts as does the natural neurotransmitter, acetylcholine, on nicotinic receptors (nachrs). |
2013-09-10 |
2023-08-12 |
Not clear |
| Lorinda K Baker, Danyan Mao, Henry Chi, Anitha P Govind, Yolanda F Vallejo, Michael Iacoviello, Stacy Herrera, James J Cortright, William N Green, Daniel S McGehee, Paul Vezin. Intermittent nicotine exposure upregulates nAChRs in VTA dopamine neurons and sensitises locomotor responding to the drug. The European journal of neuroscience. vol 37. issue 6. 2013-08-29. PMID:23331514. |
here we show that activation of nicotinic acetylcholine receptors (nachrs) in the vta, but not the nacc, is essential for the induction of locomotor sensitisation by nicotine. |
2013-08-29 |
2023-08-12 |
Not clear |
| Kia J Jackson, M Imad Dama. Beta2-containing nicotinic acetylcholine receptors mediate calcium/calmodulin-dependent protein kinase-II and synapsin I protein levels in the nucleus accumbens after nicotine withdrawal in mice. European journal of pharmacology. vol 701. issue 1-3. 2013-08-22. PMID:23313759. |
beta2-containing nicotinic acetylcholine receptors mediate calcium/calmodulin-dependent protein kinase-ii and synapsin i protein levels in the nucleus accumbens after nicotine withdrawal in mice. |
2013-08-22 |
2023-08-12 |
mouse |
| Kia J Jackson, M Imad Dama. Beta2-containing nicotinic acetylcholine receptors mediate calcium/calmodulin-dependent protein kinase-II and synapsin I protein levels in the nucleus accumbens after nicotine withdrawal in mice. European journal of pharmacology. vol 701. issue 1-3. 2013-08-22. PMID:23313759. |
nicotinic acetylcholine receptors are calcium-permeable and the initial targets for nicotine. |
2013-08-22 |
2023-08-12 |
mouse |
| Reeta Talka, Outi Salminen, Paul Whiteaker, Ronald J Lukas, Raimo K Tuomine. Nicotine-morphine interactions at α4β2, α7 and α3(⁎) nicotinic acetylcholine receptors. European journal of pharmacology. vol 701. issue 1-3. 2013-08-22. PMID:23340223. |
we studied receptor-level interactions of nicotine and morphine at α4β2, α7 and α3(⁎) nicotinic acetylcholine receptors. |
2013-08-22 |
2023-08-12 |
Not clear |