| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Erin King, Alana Campbell, Aysenil Belger, Karen Grewe. Prenatal Nicotine Exposure Disrupts Infant Neural Markers of Orienting. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 20. issue 7. 2019-09-10. PMID:29059450. |
nicotine binds to nicotinic acetylcholine receptors, which are extensively involved in growth, connectivity, and function of developing neural circuitry and neurotransmitter systems. |
2019-09-10 |
2023-08-13 |
Not clear |
| Yoshinobu Kamio, Takeshi Miyamoto, Tetsuro Kimura, Kazuha Mitsui, Hajime Furukawa, Dingding Zhang, Kimihiko Yokosuka, Masaaki Korai, Daisuke Kudo, Ronald J Lukas, Michael T Lawton, Tomoki Hashimot. Roles of Nicotine in the Development of Intracranial Aneurysm Rupture. Stroke. vol 49. issue 10. 2019-09-10. PMID:30355112. |
nicotine's interactions with vascular cell nicotinic acetylcholine receptors containing α7 subunits (α7*-nachr) are thought to promote local inflammation and sustained angiogenesis. |
2019-09-10 |
2023-08-13 |
mouse |
| Wuyi Liu, Kunkai S. A Review on the Receptor-ligand Molecular Interactions in the Nicotinic Receptor Signaling Systems. Pakistan journal of biological sciences : PJBS. vol 21. issue 2. 2019-08-07. PMID:30221881. |
nicotine is regarded as the main active addictive ingredient in tobacco products driving continued tobacco abuse behavior (smoking) to the addiction behavior, whereas nicotinic acetylcholine receptors (nachr) is the crucial effective apparatus or molecular effector of nicotine and acetylcholine and other similar ligands. |
2019-08-07 |
2023-08-13 |
Not clear |
| Wuyi Liu, Kunkai S. A Review on the Receptor-ligand Molecular Interactions in the Nicotinic Receptor Signaling Systems. Pakistan journal of biological sciences : PJBS. vol 21. issue 2. 2019-08-07. PMID:30221881. |
many nachr subunits have been revealed to bind to either neurotransmitters or exogenous ligands, such as nicotine and acetylcholine, being involved in the nicotinic receptor signal transduction. |
2019-08-07 |
2023-08-13 |
Not clear |
| Wuyi Liu, Kunkai S. A Review on the Receptor-ligand Molecular Interactions in the Nicotinic Receptor Signaling Systems. Pakistan journal of biological sciences : PJBS. vol 21. issue 2. 2019-08-07. PMID:30221881. |
all the references were carefully retrieved from the pubmed database by searching key words "nicotine", "acetylcholine", "nicotinic acetylcholine receptor(s)", "nachr*", "protein and nachr", "lipid and nachr", "smok*" and "tobacco". |
2019-08-07 |
2023-08-13 |
Not clear |
| Helen Keyworth, Polymnia Georgiou, Panos Zanos, André Veloso Rueda, Ying Chen, Ian Kitchen, Rosana Camarini, Mark Cropley, Alexis Baile. Wheel running during chronic nicotine exposure is protective against mecamylamine-precipitated withdrawal and up-regulates hippocampal α7 nACh receptors in mice. British journal of pharmacology. vol 175. issue 11. 2019-08-06. PMID:29266170. |
we investigated, in a mouse model, the effect of exercise intensity during chronic nicotine exposure on nicotine withdrawal severity, binding of α4β2*, α7 nicotinic acetylcholine (nachr), μ-opioid (μ receptors) and d |
2019-08-06 |
2023-08-13 |
mouse |
| S Lauren Kyte, David A Gewirt. The Influence of Nicotine on Lung Tumor Growth, Cancer Chemotherapy, and Chemotherapy-Induced Peripheral Neuropathy. The Journal of pharmacology and experimental therapeutics. vol 366. issue 2. 2019-08-05. PMID:29866790. |
studies in animal models have suggested that nicotine, an agonist of nicotinic acetylcholine receptors, may have the potential to prevent and/or reverse the peripheral neuropathy induced by cancer chemotherapeutic drugs, such as paclitaxel and oxaliplatin. |
2019-08-05 |
2023-08-13 |
Not clear |
| Scott T Barrett, Trevor N Geary, Amy N Steiner, Rick A Bevin. A behavioral economic analysis of the value-enhancing effects of nicotine and varenicline and the role of nicotinic acetylcholine receptors in male and female rats. Behavioural pharmacology. vol 29. issue 6. 2019-08-01. PMID:29634495. |
a behavioral economic analysis of the value-enhancing effects of nicotine and varenicline and the role of nicotinic acetylcholine receptors in male and female rats. |
2019-08-01 |
2023-08-13 |
rat |
| Scott T Barrett, Trevor N Geary, Amy N Steiner, Rick A Bevin. A behavioral economic analysis of the value-enhancing effects of nicotine and varenicline and the role of nicotinic acetylcholine receptors in male and female rats. Behavioural pharmacology. vol 29. issue 6. 2019-08-01. PMID:29634495. |
the role of α4β2* and α7 nicotinic acetylcholine receptors (nachrs) in the enhancing effects of nicotine and varenicline is also evaluated. |
2019-08-01 |
2023-08-13 |
rat |
| Yeongkwon Son, Olivia Wackowski, Clifford Weisel, Stephan Schwander, Gediminas Mainelis, Cristine Delnevo, Qingyu Men. Evaluation of E-Vapor Nicotine and Nicotyrine Concentrations under Various E-Liquid Compositions, Device Settings, and Vaping Topographies. Chemical research in toxicology. vol 31. issue 9. 2019-07-29. PMID:30080399. |
however, higher serum nicotine levels might increase cancer risks by stimulating nicotinic acetylcholine receptors (nachrs). |
2019-07-29 |
2023-08-13 |
human |
| Stephen R Baldassarri, Ansel T Hillmer, Jon Mikael Anderson, Peter Jatlow, Nabeel Nabulsi, David Labaree, Kelly P Cosgrove, Stephanie S O'Malley, Thomas Eissenberg, Suchitra Krishnan-Sarin, Irina Esterli. Use of Electronic Cigarettes Leads to Significant Beta2-Nicotinic Acetylcholine Receptor Occupancy: Evidence From a PET Imaging Study. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 20. issue 4. 2019-07-25. PMID:28460123. |
we investigated if nicotine from ecs is delivered to the brain β2*-nicotinic acetylcholine receptors (β2*-nachr) and how this relates to the behavioral effects and nicotine delivery from cigarettes. |
2019-07-25 |
2023-08-13 |
Not clear |
| Dahua Yu, Kai Yuan, Jiadong Cheng, Yanyan Guan, Yangding Li, Yanzhi Bi, Jinquan Zhai, Lin Luo, Bo Liu, Ting Xue, Xiaoqi L. Reduced Thalamus Volume May Reflect Nicotine Severity in Young Male Smokers. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 20. issue 4. 2019-07-25. PMID:28651369. |
nicotine acts as an agonist at presynaptic nicotinic acetylcholine receptors and to facilitate synaptic release of several neurotransmitters including dopamine and glutamate. |
2019-07-25 |
2023-08-13 |
Not clear |
| Dahua Yu, Kai Yuan, Jiadong Cheng, Yanyan Guan, Yangding Li, Yanzhi Bi, Jinquan Zhai, Lin Luo, Bo Liu, Ting Xue, Xiaoqi L. Reduced Thalamus Volume May Reflect Nicotine Severity in Young Male Smokers. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 20. issue 4. 2019-07-25. PMID:28651369. |
the thalamus has the highest density of nicotinic acetylcholine receptors in the brain, which may make this area more vulnerable to the addictive effects of nicotine. |
2019-07-25 |
2023-08-13 |
Not clear |
| Joao A Paulo, Steven P Gyg. Isobaric Tag-Based Protein Profiling of a Nicotine-Treated Alpha7 Nicotinic Receptor-Null Human Haploid Cell Line. Proteomics. vol 18. issue 11. 2019-07-10. PMID:29663646. |
nicotinic acetylcholine receptors (nachr), the primary cell surface targets of nicotine, have implications in various neurological disorders. |
2019-07-10 |
2023-08-13 |
human |
| In Soo Ryu, Jieun Kim, Su Yeon Seo, Ju Hwan Yang, Jeong Hwan Oh, Dong Kun Lee, Hyun-Wook Cho, Seong Shoon Yoon, Joung-Wook Seo, Suchan Chang, Hee Young Kim, Insop Shim, Eun Sang Cho. Behavioral changes after nicotine challenge are associated with α7 nicotinic acetylcholine receptor-stimulated glutamate release in the rat dorsal striatum. Scientific reports. vol 7. issue 1. 2019-07-08. PMID:29118361. |
behavioral changes after nicotine challenge are associated with α7 nicotinic acetylcholine receptor-stimulated glutamate release in the rat dorsal striatum. |
2019-07-08 |
2023-08-13 |
rat |
| In Soo Ryu, Jieun Kim, Su Yeon Seo, Ju Hwan Yang, Jeong Hwan Oh, Dong Kun Lee, Hyun-Wook Cho, Seong Shoon Yoon, Joung-Wook Seo, Suchan Chang, Hee Young Kim, Insop Shim, Eun Sang Cho. Behavioral changes after nicotine challenge are associated with α7 nicotinic acetylcholine receptor-stimulated glutamate release in the rat dorsal striatum. Scientific reports. vol 7. issue 1. 2019-07-08. PMID:29118361. |
blockade of α7 nicotinic acetylcholine receptors (nachrs) significantly decreased the nicotine challenge-induced increases in extracellular glutamate concentrations and locomotor and rearing activities. |
2019-07-08 |
2023-08-13 |
rat |
| Paul M Klenowski, Andrew R Tappe. Molecular, Neuronal, and Behavioral Effects of Ethanol and Nicotine Interactions. Handbook of experimental pharmacology. vol 248. 2019-06-12. PMID:29423839. |
interactions between ethanol and nicotine can also occur via common molecular targets including nicotinic acetylcholine receptors (nachrs). |
2019-06-12 |
2023-08-13 |
Not clear |
| Nicolas Deperrois, Victoria Moiseeva, Boris Gutki. Minimal Circuit Model of Reward Prediction Error Computations and Effects of Nicotinic Modulations. Frontiers in neural circuits. vol 12. 2019-06-03. PMID:30687021. |
furthermore, endogenous acetylcholine and exogenous nicotine, also likely affect these computations by acting on both vta da and gaba (γ -aminobutyric acid) neurons via nicotinic-acetylcholine receptors (nachrs). |
2019-06-03 |
2023-08-13 |
Not clear |
| Nicolas Deperrois, Victoria Moiseeva, Boris Gutki. Minimal Circuit Model of Reward Prediction Error Computations and Effects of Nicotinic Modulations. Frontiers in neural circuits. vol 12. 2019-06-03. PMID:30687021. |
by including models of nachr-mediated currents in the vta da-gaba circuit, we showed that nicotine should reduce the acetylcholine action on the vta gaba neurons by receptor desensitization and potentially boost da responses to reward-related signals in a non-trivial manner. |
2019-06-03 |
2023-08-13 |
Not clear |
| Sambashiva Banala, Matthew C Arvin, Nicholas M Bannon, Xiao-Tao Jin, John J Macklin, Yong Wang, Can Peng, Guiqing Zhao, John J Marshall, Kyle R Gee, David L Wokosin, Veronica J Kim, J Michael McIntosh, Anis Contractor, Henry A Lester, Yevgenia Kozorovitskiy, Ryan M Drenan, Luke D Lavi. Photoactivatable drugs for nicotinic optopharmacology. Nature methods. vol 15. issue 5. 2019-05-10. PMID:29578537. |
we prepared a photoactivatable nicotine (pa-nic), uncageable via one- or two-photon excitation, that is useful to study nicotinic acetylcholine receptors (nachrs) in different experimental preparations and spatiotemporal scales. |
2019-05-10 |
2023-08-13 |
Not clear |