| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Namita Pandey, Soumyadip Pal, Lokesh Kumar Sharma, Randeep Guleria, Anant Mohan, Tapasya Srivastav. SNP rs16969968 as a Strong Predictor of Nicotine Dependence and Lung Cancer Risk in a North Indian Population Asian Pacific journal of cancer prevention : APJCP. vol 18. issue 11. 2019-11-20. PMID:29172281. |
snp rs16969968 as a strong predictor of nicotine dependence and lung cancer risk in a north indian population background: the 15q24-25 loci contain genes (chrna5 and chrna3) encoding nicotinic acetylcholine receptorsubunits. |
2019-11-20 |
2023-08-13 |
human |
| Mami Noda, A I Kobayash. Correction to: Nicotine inhibits activation of microglial proton currents via interactions with α7 acetylcholine receptors. The journal of physiological sciences : JPS. vol 68. issue 6. 2019-11-20. PMID:29679307. |
correction to: nicotine inhibits activation of microglial proton currents via interactions with α7 acetylcholine receptors. |
2019-11-20 |
2023-08-13 |
Not clear |
| Mami Noda, A I Kobayash. Correction to: Nicotine inhibits activation of microglial proton currents via interactions with α7 acetylcholine receptors. The journal of physiological sciences : JPS. vol 68. issue 6. 2019-11-20. PMID:29679307. |
the article nicotine inhibits activation of microglial proton currents via interactions with α7 acetylcholine receptors, written by mami noda and ai kobayashi, was originally published online first without open access. |
2019-11-20 |
2023-08-13 |
Not clear |
| Hui Wen Ng, Carmine Leggett, Sugunadevi Sakkiah, Bohu Pan, Hao Ye, Leihong Wu, Chandrabose Selvaraj, Weida Tong, Huixiao Hon. Competitive docking model for prediction of the human nicotinic acetylcholine receptor α7 binding of tobacco constituents. Oncotarget. vol 9. issue 24. 2019-11-20. PMID:29682193. |
nicotinic acetylcholine receptors (nachrs) are the targets of nicotine and are responsible for addiction to tobacco products. |
2019-11-20 |
2023-08-13 |
human |
| R A Mitchell, H H Loeschcke, W H Massion, J W Severinghau. Respiratory responses mediated through superficial chemosensitive areas on the medulla Journal of applied physiology (Bethesda, Md. : 1985). vol 18. issue 3. 2019-11-20. PMID:31094494. |
respiratory stimulation was elicited from this region by increased pco2 and (h+), nicotine, and acetylcholine; and respiratory depression by procaine, nacn, lobeline, cold csf, decreased pco2 and (h+). |
2019-11-20 |
2023-08-13 |
Not clear |
| R A Mitchell, H H Loeschcke, W H Massion, J W Severinghau. Respiratory responses mediated through superficial chemosensitive areas on the medulla Journal of applied physiology (Bethesda, Md. : 1985). vol 18. issue 3. 2019-11-20. PMID:31094494. |
when placed in the fourth ventricle, procaine and high (h+) and pco2 did not affect respiration, but nicotine and acetylcholine depressed it. |
2019-11-20 |
2023-08-13 |
Not clear |
| Stephen J Page, Mingyan Zhu, Suzanne M Appleyar. Effects of acute and chronic nicotine on catecholamine neurons of the nucleus of the solitary tract. American journal of physiology. Regulatory, integrative and comparative physiology. vol 316. issue 1. 2019-11-19. PMID:30354182. |
one site of action is the nucleus of the solitary tract (nts), where nicotine initiates a stress response and modulates cardiovascular and gastric function through nicotinic acetylcholine receptors (nachrs). |
2019-11-19 |
2023-08-13 |
mouse |
| Stefan Passlick, Ek Raj Thapaliya, Zuxin Chen, Matthew T Richers, Graham C R Ellis-Davie. Optical probing of acetylcholine receptors on neurons in the medial habenula with a novel caged nicotine drug analogue. The Journal of physiology. vol 596. issue 22. 2019-11-18. PMID:30222192. |
optical probing of acetylcholine receptors on neurons in the medial habenula with a novel caged nicotine drug analogue. |
2019-11-18 |
2023-08-13 |
Not clear |
| Jaspreet Kaur, Rossana Rauti, Andrea Nistr. Nicotine-mediated neuroprotection of rat spinal networks against excitotoxicity. The European journal of neuroscience. vol 47. issue 11. 2019-11-04. PMID:29770521. |
activation of neuronal nicotinic acetylcholine receptors (nachrs) by nicotine is reported to protect brain neurons from glutamate excitotoxicity. |
2019-11-04 |
2023-08-13 |
rat |
| Afshin Ebrahimpour, Samana Shrestha, Mark D Bonnen, N Tony Eissa, Ganesh Raghu, Yohannes T Ghebr. Nicotine Modulates Growth Factors and MicroRNA to Promote Inflammatory and Fibrotic Processes. The Journal of pharmacology and experimental therapeutics. vol 368. issue 2. 2019-11-04. PMID:30446578. |
nicotine is a bioactive molecule that acts upon nicotinic acetylcholine receptors expressed on neuronal and non-neuronal cells including endothelial cells. |
2019-11-04 |
2023-08-13 |
Not clear |
| Luis M Carcoba, Rodolfo J Flores, Luis A Natividad, Laura E O'Del. Amino acid modulation of dopamine in the nucleus accumbens mediates sex differences in nicotine withdrawal. Addiction biology. vol 23. issue 5. 2019-10-22. PMID:28940989. |
nicotine withdrawal induces decreases in nac dopamine and increases in acetylcholine (ach) levels in male rats. |
2019-10-22 |
2023-08-13 |
rat |
| J Hernandez, A Volland, B J Leyshon, M Juda, J M Ridlon, R W Johnson, A J Steelma. Effect of imidacloprid ingestion on immune responses to porcine reproductive and respiratory syndrome virus. Scientific reports. vol 8. issue 1. 2019-10-21. PMID:30072754. |
nicotine and acetylcholine cause immunosuppresion by signaling to the α7 nicotinic acetylcholine receptor (α7 nachr) on immune cells. |
2019-10-21 |
2023-08-13 |
Not clear |
| Tongyuan Hu, Zhongli Yang, Ming D L. Pharmacological Effects and Regulatory Mechanisms of Tobacco Smoking Effects on Food Intake and Weight Control. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 13. issue 4. 2019-10-07. PMID:30054897. |
nicotine's weight effects appear to result especially from the drug's stimulation of α3β4 nicotine acetylcholine receptors (nachrs), which are located on pro-opiomelanocortin (pomc) neurons in the arcuate nucleus (arc), leading to activation of the melanocortin circuit, which is associated with body weight. |
2019-10-07 |
2023-08-13 |
Not clear |
| Haijun Han, Zhongli Yang, Sulie L Chang, Ming D L. Modulatory Effects of Nicotine on neuroHIV/neuroAIDS. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 13. issue 4. 2019-10-07. PMID:30215204. |
nicotine, one of the key active ingredients in tobacco smoke, exerts its effects via binding to nicotinic acetylcholine receptors (nachrs). |
2019-10-07 |
2023-08-13 |
human |
| Lila Buls Wollman, Richard B Levine, Ralph F Fregos. Developmental nicotine exposure alters glycinergic neurotransmission to hypoglossal motoneurons in neonatal rats. Journal of neurophysiology. vol 120. issue 3. 2019-10-01. PMID:29847237. |
glycinergic spontaneous and miniature inhibitory postsynaptic currents (sipsc/mipsc) were recorded from xiimns in brain stem slices from 1- to 5-day-old rat pups of either sex, under baseline conditions and following stimulation of nicotinic acetylcholine (ach) receptors with nicotine (i.e., an acute nicotine challenge). |
2019-10-01 |
2023-08-13 |
rat |
| Lila Buls Wollman, Richard B Levine, Ralph F Fregos. Developmental nicotine exposure alters glycinergic neurotransmission to hypoglossal motoneurons in neonatal rats. Journal of neurophysiology. vol 120. issue 3. 2019-10-01. PMID:29847237. |
new & noteworthy here we show that perinatal nicotine exposure does not impact baseline glycinergic neurotransmission to hypoglossal motoneurons but enhances glycinergic inputs to hypoglossal motoneurons in response to activation of nicotinic acetylcholine (ach) receptors with acute nicotine. |
2019-10-01 |
2023-08-13 |
rat |
| Qingxiang Liu, Jianfeng Xie, Yi Yan. [Advances in the regulation mechanism of cholinergic anti-inflammatory pathway on sepsis]. Zhonghua wei zhong bing ji jiu yi xue. vol 31. issue 6. 2019-09-17. PMID:31315742. |
the cholinergic anti-inflammatory pathway releases acetylcholine (ach) through the vaginal nerve and acts on the surface of the inflammatory cell α7 nicotine acetylcholine receptor (α7nachr) to inhibit the production of inflammatory factors, so that the inflammatory response tends to be balanced. |
2019-09-17 |
2023-08-13 |
Not clear |
| Laya Takbiri Osgoei, Kazem Parivar, Marzieh Ebrahimi, Esmaeil Morta. Nicotine Modulates the Release of Inflammatory Cytokines and Expression of TLR2, TLR4 of Cord Blood Mononuclear Cells. Iranian journal of allergy, asthma, and immunology. vol 17. issue 4. 2019-09-12. PMID:30537800. |
nicotine rapidly crosses the blood-brain barrier (10 to 20 s) and binds to nicotinic acetylcholine receptors (nachrs). |
2019-09-12 |
2023-08-13 |
human |
| Ayman K Hamouda, Asti Jackson, Deniz Bagdas, M Imad Dama. Reversal of Nicotine Withdrawal Signs Through Positive Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors in Male Mice. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 20. issue 7. 2019-09-10. PMID:29059422. |
reversal of nicotine withdrawal signs through positive allosteric modulation of α4β2 nicotinic acetylcholine receptors in male mice. |
2019-09-10 |
2023-08-13 |
mouse |
| Ayman K Hamouda, Asti Jackson, Deniz Bagdas, M Imad Dama. Reversal of Nicotine Withdrawal Signs Through Positive Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors in Male Mice. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 20. issue 7. 2019-09-10. PMID:29059422. |
unlike us food and drug administration approved smoke cessation aids (nicotine and varenicline) which act as nicotinic acetylcholine receptors (nachrs) agonists, desformylflustrabromine (dfbr) acts as a nachr positive allosteric modulator with higher selectivity to the α4β2 nachr. |
2019-09-10 |
2023-08-13 |
mouse |