All Relations between Nicotine and acetylcholine

Publication Sentence Publish Date Extraction Date Species
Marcela Waisman Campos, Debora Serebrisky, Joao Mauricio Castaldelli-Mai. Smoking and Cognition. Current drug abuse reviews. vol 9. issue 2. 2018-05-28. PMID:27492358. given the large availability of nicotinic acetylcholine receptors (nachrs) throughout the brain, and the wide range of neurotransmitter systems affected (norepinephrine, serotonin and dopamine), nicotine influences a wide variety of cognitive domains such as sensorial, motor, attention, executive function, learning and memory. 2018-05-28 2023-08-13 Not clear
Vivien Kauschke, Annett Gebert, Mariana Calin, Jürgen Eckert, Sebastian Scheich, Christian Heiss, Katrin Susanne Lip. Effects of new beta-type Ti-40Nb implant materials, brain-derived neurotrophic factor, acetylcholine and nicotine on human mesenchymal stem cells of osteoporotic and non osteoporotic donors. PloS one. vol 13. issue 2. 2018-05-28. PMID:29489907. effects of new beta-type ti-40nb implant materials, brain-derived neurotrophic factor, acetylcholine and nicotine on human mesenchymal stem cells of osteoporotic and non osteoporotic donors. 2018-05-28 2023-08-13 human
Parastoo Javadi, Ameneh Rezayof, Maryam Sardari, Zahra Ghasemzade. Brain nicotinic acetylcholine receptors are involved in stress-induced potentiation of nicotine reward in rats. Journal of psychopharmacology (Oxford, England). vol 31. issue 7. 2018-04-10. PMID:28541827. brain nicotinic acetylcholine receptors are involved in stress-induced potentiation of nicotine reward in rats. 2018-04-10 2023-08-13 rat
Parastoo Javadi, Ameneh Rezayof, Maryam Sardari, Zahra Ghasemzade. Brain nicotinic acetylcholine receptors are involved in stress-induced potentiation of nicotine reward in rats. Journal of psychopharmacology (Oxford, England). vol 31. issue 7. 2018-04-10. PMID:28541827. these findings suggest that exposure to elevated platform stress potentiates the rewarding effect of nicotine which may be associated with the involvement of nicotinic acetylcholine receptors. 2018-04-10 2023-08-13 rat
Theodore A Slotkin, Ashley Stadler, Samantha Skavicus, Jennifer Card, Jonathan Ruff, Edward D Levin, Frederic J Seidle. Is There a Critical Period for the Developmental Neurotoxicity of Low-Level Tobacco Smoke Exposure? Toxicological sciences : an official journal of the Society of Toxicology. vol 155. issue 1. 2018-04-02. PMID:27633979. we evaluated in rats whether there is a critical period during which tobacco smoke extract (tse) affects the development of acetylcholine and serotonin systems, prominent targets for adverse effects of nicotine and tobacco smoke. 2018-04-02 2023-08-13 rat
Caitlin Askew, Irakli Intskirveli, Raju Metherat. Systemic Nicotine Increases Gain and Narrows Receptive Fields in A1 via Integrated Cortical and Subcortical Actions. eNeuro. vol 4. issue 3. 2018-04-02. PMID:28660244. nicotine enhances sensory and cognitive processing via actions at nicotinic acetylcholine receptors (nachrs), yet the precise circuit- and systems-level mechanisms remain unclear. 2018-04-02 2023-08-13 mouse
Yao Zhang, Yanfei Jia, Ping Li, Huanjie Li, Dongjie Xiao, Yunshan Wang, Xiaoli M. Reciprocal activation of α5-nAChR and STAT3 in nicotine-induced human lung cancer cell proliferation. Journal of genetics and genomics = Yi chuan xue bao. vol 44. issue 7. 2018-03-19. PMID:28750889. nicotine, the addictive component of cigarettes, induces lung cancer cell proliferation, invasion and migration via the activation of nicotinic acetylcholine receptors (nachrs). 2018-03-19 2023-08-13 human
Alireza Majdi, Farzin Kamari, Manouchehr Seyedi Vafaee, Saeed Sadigh-Etegha. Revisiting nicotine's role in the ageing brain and cognitive impairment. Reviews in the neurosciences. vol 28. issue 7. 2018-03-05. PMID:28586306. nicotine is an exogenous agonist of nicotinic acetylcholine receptors (nachrs) and acts as a pharmacological chaperone in the regulation of nachr expression, potentially intervening in age-related changes in diverse molecular pathways leading to pathology. 2018-03-05 2023-08-13 Not clear
Veronika J Baumann, Ursula Koc. Perinatal nicotine exposure impairs the maturation of glutamatergic inputs in the auditory brainstem. The Journal of physiology. vol 595. issue 11. 2018-02-26. PMID:28190266. perinatal nicotine exposure delayed the developmental downregulation of functional nicotinic acetylcholine receptors on these neurons. 2018-02-26 2023-08-13 Not clear
Jie Qian, Shobha Mummalaneni, John R Grider, M Imad Damaj, Vijay Lyal. Nicotinic acetylcholine receptors (nAChRs) are expressed in Trpm5 positive taste receptor cells (TRCs). PloS one. vol 13. issue 1. 2018-02-21. PMID:29293602. the agonists and antagonists of nicotinic acetylcholine receptors (nachrs) modulate neural and behavioral responses to nicotine in wildtype (wt) mice, trpm5 ko mice and rats. 2018-02-21 2023-08-13 mouse
Elise Kleeman, Sakura Nakauchi, Hailing Su, Richard Dang, Marcelo A Wood, Katumi Sumikaw. Impaired function of α2-containing nicotinic acetylcholine receptors on oriens-lacunosum moleculare cells causes hippocampus-dependent memory impairments. Neurobiology of learning and memory. vol 136. 2018-02-15. PMID:27660076. in rodent models of smoking during pregnancy, early postnatal nicotine exposure results in impaired long-term hippocampus-dependent memory, functional loss of α2-containing nicotinic acetylcholine receptors (α2 2018-02-15 2023-08-13 Not clear
Chun Zhang, Xu-Ping Ding, Qing-Nan Zhao, Xin-Jie Yang, Shi-Min An, Hao Wang, Lu Xu, Liang Zhu, Hong-Zhuan Che. Role of α7-nicotinic acetylcholine receptor in nicotine-induced invasion and epithelial-to-mesenchymal transition in human non-small cell lung cancer cells. Oncotarget. vol 7. issue 37. 2018-01-29. PMID:27409670. nicotine via nicotinic acetylcholine receptors (nachrs) stimulates non-small cell lung cancer (nsclc) cell invasion and epithelial to mesenchymal transition (emt) which underpin the cancer metastasis. 2018-01-29 2023-08-13 human
Bo Zhang, Pamela Madden, Junchen Gu, Xiaoyun Xing, Savita Sankar, Jennifer Flynn, Kristen Kroll, Ting Wan. Uncovering the transcriptomic and epigenomic landscape of nicotinic receptor genes in non-neuronal tissues. BMC genomics. vol 18. issue 1. 2018-01-22. PMID:28583088. nicotinic acetylcholine receptors (nachrs) play an important role in cellular physiology and human nicotine dependence, and are closely associated with many human diseases including cancer. 2018-01-22 2023-08-13 human
Kazuyuki Fukushima, Kazuto Yamazaki, Norimasa Miyamoto, Kohei Sawad. Functional Characterization of Acetylcholine Receptors Expressed in Human Neurons Differentiated from Hippocampal Neural Stem/Progenitor Cells. Journal of biomolecular screening. vol 21. issue 10. 2018-01-19. PMID:27572608. intracellular calcium flux in 4-week differentiated hip-009 cells demonstrated that the cells responded to acetylcholine, nicotine, and muscarine in a concentration-dependent manner (ec 2018-01-19 2023-08-13 human
Jose A Matta, Shenyan Gu, Weston B Davini, Brian Lord, Edward R Siuda, Anthony W Harrington, David S Bred. NACHO Mediates Nicotinic Acetylcholine Receptor Function throughout the Brain. Cell reports. vol 19. issue 4. 2018-01-19. PMID:28445721. neuronal nicotinic acetylcholine receptors (nachrs) participate in diverse aspects of brain function and mediate behavioral and addictive properties of nicotine. 2018-01-19 2023-08-13 mouse
Monica M Marcus, Carl Björkholm, Anna Malmerfelt, Annie Möller, Ninni Påhlsson, Åsa Konradsson-Geuken, Kristin Feltmann, Kent Jardemark, Björn Schilström, Torgny H Svensso. Alpha7 nicotinic acetylcholine receptor agonists and PAMs as adjunctive treatment in schizophrenia. An experimental study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 9. 2018-01-18. PMID:27474687. nicotine has been found to improve cognition and reduce negative symptoms in schizophrenia and a genetic and pathophysiological link between the α7 nicotinic acetylcholine receptors (nachrs) and schizophrenia has been demonstrated. 2018-01-18 2023-08-13 rat
Naofumi Kunisawa, Higor A Iha, Saki Shimizu, Kentaro Tokudome, Takahiro Mukai, Masato Kinboshi, Tadao Serikawa, Yukihiro Ohn. Nicotine evokes kinetic tremor by activating the inferior olive via α7 nicotinic acetylcholine receptors. Behavioural brain research. vol 314. 2018-01-18. PMID:27506652. nicotine evokes kinetic tremor by activating the inferior olive via α7 nicotinic acetylcholine receptors. 2018-01-18 2023-08-13 mouse
Melissa J Guildford, Anthony V Sacino, Andrew R Tappe. Modulation of ethanol reward sensitivity by nicotinic acetylcholine receptors containing the α6 subunit. Alcohol (Fayetteville, N.Y.). vol 57. 2018-01-03. PMID:27793544. nicotine, the addictive component of tobacco, activates nicotinic acetylcholine receptors (nachrs) containing the α6 subunit (α6* nachrs) in dopaminergic (daergic) neurons of the ventral tegmental area (vta), a region known to be crucial for drug reward. 2018-01-03 2023-08-13 mouse
Lauriane Harrington, Xavier Viñals, Andrea Herrera-Solís, Africa Flores, Carole Morel, Stefania Tolu, Philippe Faure, Rafael Maldonado, Uwe Maskos, Patricia Robled. Role of β4* Nicotinic Acetylcholine Receptors in the Habenulo-Interpeduncular Pathway in Nicotine Reinforcement in Mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 7. 2018-01-02. PMID:26585290. role of β4* nicotinic acetylcholine receptors in the habenulo-interpeduncular pathway in nicotine reinforcement in mice. 2018-01-02 2023-08-13 mouse
Dong-Wook Jeon, Joo-Cheol Shim, Bo-Geum Kong, Jung-Joon Moon, Young-Soo Seo, Sung-Jin Kim, Min-Kyung Oh, Do-Un Jun. Adjunctive varenicline treatment for smoking reduction in patients with schizophrenia: A randomized double-blind placebo-controlled trial. Schizophrenia research. vol 176. issue 2-3. 2017-12-21. PMID:27543252. varenicline, a partial and full agonist at the α4β2 and α7 nicotine acetylcholine receptors, respectively, has been shown to be an effective anti-smoking treatment. 2017-12-21 2023-08-13 Not clear