| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A R Wakade, R K Malhotra, T D Wakade, W R Dixo. Simultaneous secretion of catecholamines from the adrenal medulla and of [3H]norepinephrine from sympathetic nerves from a single test preparation: different effects of agents on the secretion. Neuroscience. vol 18. issue 4. 1986-11-14. PMID:3762930. |
nicotine, muscarine and acetylcholine enhanced the secretion of catecholamines but not tritium, whereas tyramine and ephedrine enhanced the secretion of tritium but not catecholamines. |
1986-11-14 |
2023-08-11 |
rat |
| G Kemp, B J Morle. Ganglionic nAChRs and high-affinity nicotinic binding sites are not equivalent. FEBS letters. vol 205. issue 2. 1986-10-23. PMID:3743777. |
high-affinity (kd approximately equal to 10 nm) binding sites for nicotine and acetylcholine (ach) have recently been identified in vertebrate brain. |
1986-10-23 |
2023-08-11 |
Not clear |
| R F Taylor, D T Frazie. Effect of nicotine and acetylcholine on crustacean muscle membrane potential. Journal of applied physiology (Bethesda, Md. : 1985). vol 61. issue 2. 1986-10-15. PMID:2875056. |
effect of nicotine and acetylcholine on crustacean muscle membrane potential. |
1986-10-15 |
2023-08-11 |
Not clear |
| R F Taylor, D T Frazie. Effect of nicotine and acetylcholine on crustacean muscle membrane potential. Journal of applied physiology (Bethesda, Md. : 1985). vol 61. issue 2. 1986-10-15. PMID:2875056. |
we have investigated the effect of nicotine and acetylcholine on the resting membrane potential of the crayfish extensor muscle in order to determine whether crustacean muscle can be activated by cholinergic compounds. |
1986-10-15 |
2023-08-11 |
Not clear |
| R F Taylor, D T Frazie. Effect of nicotine and acetylcholine on crustacean muscle membrane potential. Journal of applied physiology (Bethesda, Md. : 1985). vol 61. issue 2. 1986-10-15. PMID:2875056. |
the resting membrane potential was measured before and after treatment with glutamate, nicotine, and acetylcholine. |
1986-10-15 |
2023-08-11 |
Not clear |
| R F Taylor, D T Frazie. Effect of nicotine and acetylcholine on crustacean muscle membrane potential. Journal of applied physiology (Bethesda, Md. : 1985). vol 61. issue 2. 1986-10-15. PMID:2875056. |
however, muscle cells showed no depolarization after treatment with nicotine (50 microm) or acetylcholine (66 microm). |
1986-10-15 |
2023-08-11 |
Not clear |
| b' D B Beleslin, S K Krsti\\xc4\\x8. Nicotine-induced convulsions in cats and central nicotinic receptors. Pharmacology, biochemistry, and behavior. vol 24. issue 6. 1986-09-17. PMID:2874565.' |
the effects were investigated of intracerebroventricular (icv) injections in the cat of ganglionic blocking agents, antimuscarinic drugs, alpha and beta adrenergic blocking substances, dopamine antagonists, an antihistamine, reserpine and a 5-hydroxytryptamine antagonist as well as the inhibitors of catecholamines, 5-hydroxytryptamine and acetylcholine synthesis upon convulsions produced by nicotine, which was similarly injected. |
1986-09-17 |
2023-08-11 |
cat |
| I G Scott, K E Akerman, J E Heikkilä, K Kaila, L C Andersso. Development of a neural phenotype in differentiating ganglion cell-derived human neuroblastoma cells. Journal of cellular physiology. vol 128. issue 2. 1986-09-17. PMID:3090056. |
acetylcholine and muscarine but not nicotine stimulate an increase in 45ca2+ influx, an effect blocked by atropine. |
1986-09-17 |
2023-08-11 |
human |
| R Borges, F Sala, A G Garcí. Continuous monitoring of catecholamine release from perfused cat adrenals. Journal of neuroscience methods. vol 16. issue 4. 1986-09-17. PMID:3736118. |
this method allowed: the recording of basal levels and fluctuations of catecholamine release with good reliability; the study of the release of catecholamines in response to even submicromolar concentrations of nicotine or acetylcholine and 3 mm increments of the k+ concentration, perfused in pulses of a few seconds, and to determine the effects of drugs and ionic manipulations on such secretory responses; the analysis of the 'physiological' secretory response evoked by electrical stimulation of the splanchnic nerves, allowing the study of presynaptic as well as postsynaptic components of the effects of drugs and ions on chemical neurotransmission at the splanchnic--chromaffin cell synapse; the continuous monitoring of the kinetics of the secretory process during sustained depolarization with several secretagogues and its correlation with the kinetics of activation and inactivation of potential sensitive ca channels. |
1986-09-17 |
2023-08-11 |
cat |
| C Larsson, L Nilsson, A Halén, A Nordber. Subchronic treatment of rats with nicotine: effects on tolerance and on [3H]acetylcholine and [3H]nicotine binding in the brain. Drug and alcohol dependence. vol 17. issue 1. 1986-07-25. PMID:3720530. |
subchronic treatment of rats with nicotine: effects on tolerance and on [3h]acetylcholine and [3h]nicotine binding in the brain. |
1986-07-25 |
2023-08-11 |
rat |
| C Larsson, L Nilsson, A Halén, A Nordber. Subchronic treatment of rats with nicotine: effects on tolerance and on [3H]acetylcholine and [3H]nicotine binding in the brain. Drug and alcohol dependence. vol 17. issue 1. 1986-07-25. PMID:3720530. |
nicotine treatment also resulted in a significant increase in [3h]acetylcholine (3h-ach) binding in the midbrain (48.3% increase in comparison with controls) and hippocampus (38.3% increase), whereas the binding of [3h]nicotine (3h-nic) was unaffected in all brain areas investigated. |
1986-07-25 |
2023-08-11 |
rat |
| P J Whitehouse, A M Martino, P G Antuono, P R Lowenstein, J T Coyle, D L Price, K J Kella. Nicotinic acetylcholine binding sites in Alzheimer's disease. Brain research. vol 371. issue 1. 1986-06-30. PMID:3708340. |
in this study, [3h]acetylcholine and [3h]nicotine were used to label nicotinic cholinergic binding sites in cerebral cortical tissues obtained at autopsy from patients with ad and from matched controls. |
1986-06-30 |
2023-08-11 |
Not clear |
| R J Luka. Characterization of curaremimetic neurotoxin binding sites on membrane fractions derived from the human medulloblastoma clonal line, TE671. Journal of neurochemistry. vol 46. issue 6. 1986-06-20. PMID:3701338. |
the kinetically determined dissociation constant for high-affinity binding of toxin is 0.56 nm (k1 = 6.3 x 10(-3) min-1 nm-1; k-1 = 3.5 x 10(-3) min-1) at 20 degrees c. nicotine, d-tubocurarine, and acetylcholine are among the most effective inhibitors of high-affinity toxin binding. |
1986-06-20 |
2023-08-11 |
human |
| Y Matsuno, N Taira, B Fujitani, T Ito, T Kadokaw. General pharmacology of the novel angiotensin converting enzyme inhibitor alacepril. 1st communication: Effects on cardiovascular, visceral and renal functions and on blood. Arzneimittel-Forschung. vol 36. issue 1. 1986-04-21. PMID:3513777. |
these three compounds neither affected the resting tension of isolated ileum in guinea-pigs and rabbits nor the contractions induced by acetylcholine, histamine, serotonin and nicotine of isolated guinea-pig ileum. |
1986-04-21 |
2023-08-11 |
mouse |
| N Limberger, L Späth, K Stark. A search for receptors modulating the release of gamma-[3H]aminobutyric acid in rabbit caudate nucleus slices. Journal of neurochemistry. vol 46. issue 4. 1986-04-16. PMID:2869105. |
the basal but not the electrically evoked overflow was enhanced by carbachol; acetylcholine and nicotine also accelerated the basal outflow whereas oxotremorine caused no consistent change; the effect of carbachol and acetylcholine were blocked by hexamethonium but not by atropine or by tetrodotoxin. |
1986-04-16 |
2023-08-11 |
rabbit |
| N Limberger, L Späth, K Stark. A search for receptors modulating the release of gamma-[3H]aminobutyric acid in rabbit caudate nucleus slices. Journal of neurochemistry. vol 46. issue 4. 1986-04-16. PMID:2869105. |
these findings indicate that the gaba neurons in the caudate nucleus may be stimulated by dopamine, although the receptor type involved remains unclear; inhibited by serotonin; and stimulated by acetylcholine acting via a nicotine receptor. |
1986-04-16 |
2023-08-11 |
rabbit |
| D A Powis, P F Bake. Alpha 2-adrenoceptors do not regulate catecholamine secretion by bovine adrenal medullary cells: a study with clonidine. Molecular pharmacology. vol 29. issue 2. 1986-03-28. PMID:2869403. |
only one set of observations has lent support to this suggestion: the rather specific alpha 2-adrenoceptor agonist clonidine inhibits catecholamine secretion evoked by the physiological secretagogue, acetylcholine, and by the related nicotinic agonists, carbachol and nicotine. |
1986-03-28 |
2023-08-11 |
cattle |
| Y Kizawa, I Takayanag. Mechanism of action of nicotine on crab-eating monkey isolated bronchial smooth muscle. Canadian journal of physiology and pharmacology. vol 63. issue 11. 1986-02-12. PMID:4075263. |
these results suggest that the response to nicotine was mediated through the release of acetylcholine, and that the nicotine-induced response may be produced through a sodium action potential independent process. |
1986-02-12 |
2023-08-11 |
human |
| M L Arruzazabala Valmaña, R González Alvare. Pharmacological characterization of ketotifen effects on guinea pig ileum. Archivum immunologiae et therapiae experimentalis. vol 33. issue 2. 1986-02-07. PMID:4084012. |
the effects of ketotifen (ke) on the contraction of isolated guinea pig ileum induced by electrical stimulation, nicotine or acetylcholine have been investigated. |
1986-02-07 |
2023-08-11 |
Not clear |
| M L Arruzazabala Valmaña, R González Alvare. Pharmacological characterization of ketotifen effects on guinea pig ileum. Archivum immunologiae et therapiae experimentalis. vol 33. issue 2. 1986-02-07. PMID:4084012. |
furthermore, ke significantly inhibits guinea pig ileum contractions induced by nicotine and acetylcholine both on innervated and denervated ileal strips. |
1986-02-07 |
2023-08-11 |
Not clear |