| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Todorov, M Papasov. Neurotransmitter interactions in smooth muscles from cat internal anal sphincter (in vitro experiments). Acta physiologica et pharmacologica Bulgarica. vol 10. issue 1. 1984-08-07. PMID:6146240. |
data are also presented concerning the release of noradrenaline through presynaptic n-cholinergic receptors, when nicotine and high acetylcholine concentrations are applied after treatment of the preparations with scorpion venom or after increasing the k+-concentration in the nutrient solution to 16-20 mmol/l. |
1984-08-07 |
2023-08-12 |
cat |
| G Almazan, D Aunis, A G García, C Montiel, G P Nicolás, P Sánchez-Garcí. Effects of collagenase on the release of [3H]-noradrenaline from bovine cultured adrenal chromaffin cells. British journal of pharmacology. vol 81. issue 4. 1984-07-18. PMID:6326921. |
release of tritium from cultured cells evoked by nicotine, acetylcholine (ach) or 59 mm k+ was very poor in 24 h-old cells; the secretory response to nicotine, ach or k+ was dramatically increased after 2-7 days of culture. |
1984-07-18 |
2023-08-12 |
cattle |
| J A Ojewol. Pharmacological analysis of the neuromuscular properties of diethylcarbamazine citrate in vitro. Methods and findings in experimental and clinical pharmacology. vol 6. issue 2. 1984-06-19. PMID:6717175. |
decc (10(-3)-2.5 x 10(-2) m) caused marked augmentation of the contractural responses of innervated chick biventer muscle preparations induced by bath-applied low concentrations of carbachol, acetylcholine or nicotine, and depressed those contractural responses of the muscle elicited by hgh concentrations of the agonists. |
1984-06-19 |
2023-08-12 |
rat |
| M Kusunoki, K Taniyama, C Tanak. Neuronal GABA release and GABA inhibition of ACh release in guinea pig urinary bladder. The American journal of physiology. vol 246. issue 4 Pt 2. 1984-05-29. PMID:6720925. |
nicotine, acetylcholine chloride (ach), and hexamethonium did not significantly alter the release of [3h]gaba. |
1984-05-29 |
2023-08-12 |
Not clear |
| J Koley, J K Saha, B N Kole. Positive inotropic effect of nicotine on electrically evoked contraction of isolated toad ventricle. Archives internationales de pharmacodynamie et de therapie. vol 267. issue 2. 1984-05-10. PMID:6712360. |
prior administration of propranolol, hexamethonium, hemicholinium-3 or guanethidine failed to antagonize the positive inotropic effect of nicotine, thus ruling out the possibility of the nicotine effect being mediated through activation of beta-adrenoceptors, ganglionic activation, presynaptic liberation of acetylcholine and liberation of norepinephrine from the sympathetic nerve endings respectively. |
1984-05-10 |
2023-08-12 |
Not clear |
| M A Visconti, A M Castrucci, D Valent. A study on melanophore receptors of Papiliochromis ramirezi (Teleostei, Cichlidae). Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 77. issue 1. 1984-03-29. PMID:6141872. |
melanosome dispersion is obtained with cholinergic drugs and the order of potency is nicotine greater than acetylcholine = pilocarpine. |
1984-03-29 |
2023-08-12 |
Not clear |
| P Boksa, B G Livet. Substance P protects against desensitization of the nicotinic response in isolated adrenal chromaffin cells. Journal of neurochemistry. vol 42. issue 3. 1984-03-23. PMID:6198467. |
substance p (10(-5) m) completely protected against desensitization of catecholamine release produced by acetylcholine at 37 degrees c or 23 degrees c and by nicotine at 23 degrees c; substance p also afforded appreciable protection against nicotine-induced desensitization at 37 degrees c. the peptide had no effect on k+-induced desensitization of catecholamine release. |
1984-03-23 |
2023-08-12 |
Not clear |
| V Ceña, G P Nicolas, P Sanchez-Garcia, S M Kirpekar, A G Garci. Pharmacological dissection of receptor-associated and voltage-sensitive ionic channels involved in catecholamine release. Neuroscience. vol 10. issue 4. 1984-03-23. PMID:6320053. |
to achieve this purpose we studied (a) the release of [3h]noradrenaline evoked by secretagogues known to trigger the secretory response through activation of receptor-associated channels (acetylcholine, nicotine), voltage-sensitive na+ (veratridine) and ca2+ (high [k+] ) channels or direct, channel-independent promotion of ca2+ entry (ionomycin); and (b) the selective blockade of some of those responses using ionic manipulations (na+ deprivation, high mg2+) or drugs known to block the activity of receptor-operated channels (imipramine, cocaine), voltage-dependent na+ (tetrodotoxin) or ca2+ (nitrendipine) channels. |
1984-03-23 |
2023-08-12 |
cattle |
| V Ceña, G P Nicolas, P Sanchez-Garcia, S M Kirpekar, A G Garci. Pharmacological dissection of receptor-associated and voltage-sensitive ionic channels involved in catecholamine release. Neuroscience. vol 10. issue 4. 1984-03-23. PMID:6320053. |
blockade by cocaine and imipramine of the release of [3h]noradrenaline evoked by acetylcholine and nicotine, without alteration of the responses to high [k+], veratridine or ionomycin, speaks in favor of a selective inactivation of the nicotinic receptor-associated channel. |
1984-03-23 |
2023-08-12 |
cattle |
| P Boksa, B G Livet. Desensitization to nicotinic cholinergic agonists and K+, agents that stimulate catecholamine secretion, in isolated adrenal chromaffin cells. Journal of neurochemistry. vol 42. issue 3. 1984-03-23. PMID:6693891. |
prior exposure of chromaffin cells to nicotinic cholinergic agonists [acetylcholine (ach) or nicotine] caused a subsequent depression or desensitization of ca release during restimulation of the cells with the same agonists. |
1984-03-23 |
2023-08-12 |
cattle |
| G Lees, D J Beadle, R P Botha. Cholinergic receptors on cultured neurones from the central nervous system of embryonic cockroaches. Brain research. vol 288. issue 1-2. 1984-03-14. PMID:6661635. |
both acetylcholine and nicotine applied by pressure ejection to the neuronal soma induced depolarizing responses and in the majority of cells tested the response was blocked by alpha-btx at a concentration of 25 nm in a time dependent manner. |
1984-03-14 |
2023-08-12 |
Not clear |
| G Lees, D J Beadle, R P Botha. Cholinergic receptors on cultured neurones from the central nervous system of embryonic cockroaches. Brain research. vol 288. issue 1-2. 1984-03-14. PMID:6661635. |
some of the neurones, however, were depolarized by acetylcholine and nicotine after 3 h incubation in alpha-btx. |
1984-03-14 |
2023-08-12 |
Not clear |
| P T Gray, H P Ran. Analysis of current noise evoked by nicotinic agonists in rat submandibular ganglion neurones. British journal of pharmacology. vol 80. issue 2. 1984-02-14. PMID:6317128. |
two kinetic components are found in the responses of these cells to acetylcholine, carbachol, suberyldicholine, dimethyl-4-phenylpiperazinium and nicotine, in agreement with previous findings of two components in evoked synaptic currents in these cells. |
1984-02-14 |
2023-08-12 |
rat |
| J Ong, D I Ker. Interactions between GABA and 5-hydroxytryptamine in the guinea-pig ileum. European journal of pharmacology. vol 94. issue 3-4. 1984-02-14. PMID:6317404. |
in isolated segments of the guinea-pig ileum, there was: (a) an early, short-lived (less than 20 s) depression by gamma-aminobutyric acid (gaba) of contractile responses to 5-hydroxytryptamine (5-ht), acetylcholine(ach), or nicotine, also seen with 3-amino-1-propanesulphonic acid (3aps) or muscimol in place of gaba, and sensitive to bicuculline, picrotoxinin or piretanide, and (b) a delayed, longer-lasting (30 s-1 min) depression of responses to 5-ht and nicotine, but not exogenously applied ach, also seen with baclofen and only antagonised by delta-aminovaleric acid (dava). |
1984-02-14 |
2023-08-12 |
Not clear |
| A R Wakade, T D Wakad. Contribution of nicotinic and muscarinic receptors in the secretion of catecholamines evoked by endogenous and exogenous acetylcholine. Neuroscience. vol 10. issue 3. 1984-01-27. PMID:6139771. |
the aim of the present study was (1) to evaluate the functional contribution of nicotinic and muscarinic receptors of the rat adrenal medullary cells in the secretion of catecholamines evoked by exogenous and endogenous acetylcholine, (2) to know whether the ratio of epinephrine to norepinephrine in the perfusate of the adrenal gland stimulated with various agents was comparable and close to that in the adrenal medulla, and (3) to study the effect of tetrodotoxin on the secretion of catecholamine evoked by nicotine and muscarine. |
1984-01-27 |
2023-08-12 |
rat |
| A R Wakade, T D Wakad. Contribution of nicotinic and muscarinic receptors in the secretion of catecholamines evoked by endogenous and exogenous acetylcholine. Neuroscience. vol 10. issue 3. 1984-01-27. PMID:6139771. |
the ratios of epinephrine to norepinephrine in the perfusate were comparable before and after stimulation of the adrenal gland with nicotine, acetylcholine, or k+; the ratio was slightly higher for muscarine. |
1984-01-27 |
2023-08-12 |
rat |
| Y Takano, Y Sakurai, Y Kohjimoto, K Honda, H O Kamiy. Presynaptic modulation of the release of dopamine from striatal synaptosomes: differences in the effects of high K+ stimulation, methamphetamine and nicotinic drugs. Brain research. vol 279. issue 1-2. 1984-01-27. PMID:6640350. |
the pattern of outflow of [3h]da and its metabolites induced by nicotine stimulants, acetylcholine (ach), nicotine and lobeline, was different from that induced by high k+ and methamphetamine. |
1984-01-27 |
2023-08-12 |
rat |
| L W Role, R L Perlma. Both nicotinic and muscarinic receptors mediate catecholamine secretion by isolated guinea-pig chromaffin cells. Neuroscience. vol 10. issue 3. 1984-01-27. PMID:6646440. |
isolated guinea-pig chromaffin cells secrete catecholamine in response to acetylcholine, nicotine, and a variety of muscarinic agonists. |
1984-01-27 |
2023-08-12 |
Not clear |
| L W Role, R L Perlma. Both nicotinic and muscarinic receptors mediate catecholamine secretion by isolated guinea-pig chromaffin cells. Neuroscience. vol 10. issue 3. 1984-01-27. PMID:6646440. |
secretion evoked by optimal concentrations of nicotine (50 microm) and muscarine (200 microm) are additive, and together these agonists cause catecholamine release equivalent to that produced by optimal concentrations of acetylcholine. |
1984-01-27 |
2023-08-12 |
Not clear |
| b' D B Beleslin, S K Krsti\\xc4\\x87, S Dozi\\xc4\\x8. Central nicotinic receptors: vomiting, ear twitching and panting. Brain research bulletin. vol 11. issue 3. 1984-01-07. PMID:6139155.' |
however, panting produced by these nicotine agonists is mediated by the mimicking action of acetylcholine on central receptors having mixed nicotinic and muscarinic properties. |
1984-01-07 |
2023-08-12 |
cat |