| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Sershen, M E Reith, A Hashim, A Lajth. Endogenous material in brain inhibiting [3H]nicotine and [3H]acetylcholine binding. Journal of neuroscience research. vol 12. issue 4. 1985-02-11. PMID:6512887. |
endogenous material in brain inhibiting [3h]nicotine and [3h]acetylcholine binding. |
1985-02-11 |
2023-08-12 |
mouse |
| H Sershen, M E Reith, A Hashim, A Lajth. Endogenous material in brain inhibiting [3H]nicotine and [3H]acetylcholine binding. Journal of neuroscience research. vol 12. issue 4. 1985-02-11. PMID:6512887. |
the material inhibited the binding of [3h]acetylcholine with the same potency as it did that of [3h]nicotine. |
1985-02-11 |
2023-08-12 |
mouse |
| O F Pomerleau, C S Pomerlea. Neuroregulators and the reinforcement of smoking: towards a biobehavioral explanation. Neuroscience and biobehavioral reviews. vol 8. issue 4. 1985-02-06. PMID:6151160. |
because nicotine alters the bioavailability of several behaviorally active neuroregulators, including acetylcholine, norepinephrine, dopamine, beta-endorphin, and vasopressin, we propose that nicotine is "used" by smokers to produce temporary improvements in performance or affect. |
1985-02-06 |
2023-08-12 |
Not clear |
| E Marmo, E Lampa, S Chieppa, G Bile, A R Romano, C Vacca, R Spadar. Antagonistic effects of guanabenz, carteolol, and muzolimine on hypertensive responses in the anesthetized dog. Research communications in chemical pathology and pharmacology. vol 46. issue 1. 1985-01-15. PMID:6505388. |
in dogs, treatment with guanabenz, carteolol, and muzolimine for 7 days, reduced the blood pressure responses to bilateral occlusion of the carotid arteries, electric stimulation of central vagus nerve, acetylcholine after atropinization, nicotine, l-noradrenaline, angiotensin ii, l-adrenaline, kc1 and asphyxia. |
1985-01-15 |
2023-08-12 |
dog |
| I Takayanagi, Y Kizawa, T Hirut. Tetrodotoxin-resistant response to nicotine in rabbit bronchial preparation. European journal of pharmacology. vol 104. issue 3-4. 1984-12-28. PMID:6499927. |
the results indicate that the release of acetylcholine evoked by nicotine was not influenced by tetrodotoxin in this preparation, and that the nicotine-induced response may be produced mainly through a sodium action potential-independent process. |
1984-12-28 |
2023-08-12 |
rabbit |
| I Takayanagi, Y Kizawa, T Hirut. Tetrodotoxin-resistant response to nicotine in rabbit bronchial preparation. European journal of pharmacology. vol 104. issue 3-4. 1984-12-28. PMID:6499927. |
we could not rule out a contribution by acetylcholine released from the acetylcholine store in the smooth muscle in the contractile mechanisms for nicotine. |
1984-12-28 |
2023-08-12 |
rabbit |
| P P Rowell, D L Winkle. Nicotinic stimulation of [3H]acetylcholine release from mouse cerebral cortical synaptosomes. Journal of neurochemistry. vol 43. issue 6. 1984-12-20. PMID:6149266. |
the effects of nicotine and 1,1-dimethyl-4-phenylpiperazinium (dmpp) on the release of newly synthesized [3h]acetylcholine in mouse cerebral cortical synaptosomes were examined. |
1984-12-20 |
2023-08-12 |
mouse |
| P P Rowell, D L Winkle. Nicotinic stimulation of [3H]acetylcholine release from mouse cerebral cortical synaptosomes. Journal of neurochemistry. vol 43. issue 6. 1984-12-20. PMID:6149266. |
nicotine and dmpp produced increases in [3h]acetylcholine release, over the level of spontaneous release, of 24% and 30%, respectively, of a maximum depolarization-induced release produced by 50 mm potassium. |
1984-12-20 |
2023-08-12 |
mouse |
| P P Rowell, D L Winkle. Nicotinic stimulation of [3H]acetylcholine release from mouse cerebral cortical synaptosomes. Journal of neurochemistry. vol 43. issue 6. 1984-12-20. PMID:6149266. |
both nicotine and dmpp also produced a slightly greater release of total tritium, measured in the absence of cholinesterase inhibition, than of [3h]acetylcholine. |
1984-12-20 |
2023-08-12 |
mouse |
| P P Rowell, D L Winkle. Nicotinic stimulation of [3H]acetylcholine release from mouse cerebral cortical synaptosomes. Journal of neurochemistry. vol 43. issue 6. 1984-12-20. PMID:6149266. |
these results indicate that the nicotinic agonists nicotine and dmpp can produce a moderate enhancement of acetylcholine release by a receptor-mediated action on cholinergic nerve terminals in the central nervous system. |
1984-12-20 |
2023-08-12 |
mouse |
| L Todorov, M Papasov. Modulation of the release of noradrenaline and of noncholinergic, nonadrenergic inhibitory neurotransmitter through presynaptic N-cholinergic receptors by means of depolarizing agents in cat internal anal sphincter. Acta physiologica et pharmacologica Bulgarica. vol 10. issue 2. 1984-11-20. PMID:6148835. |
the relaxation effects of exogenously applied acetylcholine (ach) and nicotine (ns on cat ias turn into contractile after treatment of the preparations with depolarizing agent (increased [k+]0 scorpion venom, ouabaine). |
1984-11-20 |
2023-08-12 |
cat |
| M Mori, H Tsushima, T Matsud. Antidiuretic effects of oxotremorine microinjected into the hypothalamic supraoptic and paraventricular nuclei in a water-loaded and ethanol-anesthetized rat. Japanese journal of pharmacology. vol 35. issue 1. 1984-10-16. PMID:6471618. |
the antidiuretic effects of oxotremorine in these nuclei as well as the effects of acetylcholine and nicotine were completely blocked by pretreatment with atropine. |
1984-10-16 |
2023-08-12 |
rat |
| M Mori, H Tsushima, T Matsud. Antidiuretic effects of oxotremorine microinjected into the hypothalamic supraoptic and paraventricular nuclei in a water-loaded and ethanol-anesthetized rat. Japanese journal of pharmacology. vol 35. issue 1. 1984-10-16. PMID:6471618. |
the pretreatment with hexamethonium inhibited partially the effects of nicotine, but was unable to inhibit the effects of oxotremorine and acetylcholine. |
1984-10-16 |
2023-08-12 |
rat |
| J P Changeux, A Devillers-Thiéry, P Chemouill. Acetylcholine receptor: an allosteric protein. Science (New York, N.Y.). vol 225. issue 4668. 1984-10-10. PMID:6382611. |
the nicotine receptor for the neurotransmitter acetylcholine is an allosteric protein composed of four different subunits assembled in a transmembrane pentamer alpha 2 beta gamma delta. |
1984-10-10 |
2023-08-12 |
Not clear |
| G Onuaguluch. Effects of piperazine citrate and of the anti-Ascaris fraction of the ethanolic extract of the bark of Polyadoa umbellata (erin) on mammalian non-vascular smooth muscle. Archives internationales de pharmacodynamie et de therapie. vol 269. issue 2. 1984-10-04. PMID:6476982. |
at 500 micrograms-4 mg/ml piperazine and the anti-ascaris fraction of the ethanolic extract of the bark of the erin tree (polyadoa umbelleta) have equipotent inhibitory effects on submaximal contractions induced by equipotent doses of acetylcholine, nicotine and 5-hydroxytryptamine on the guinea-pig ileum and the rabbit duodenum. |
1984-10-04 |
2023-08-12 |
rat |
| J Fontaine, J P Famaey, J Reus. Potentiation by sulphydryl agents of the responses of guinea-pig isolated ileum to various agonists. The Journal of pharmacy and pharmacology. vol 36. issue 7. 1984-09-19. PMID:6146689. |
sulphydryl agents (dithiothreitol, mercaptoethanol, monothioglycerol, cysteine, glutathione) increase non-specifically the potency of various agonists (acetylcholine, 5-hydroxytryptamine, nicotine, bradykinin, prostaglandin e2) on the guinea-pig ileum. |
1984-09-19 |
2023-08-12 |
Not clear |
| J W Sloan, G D Todd, W R Marti. Nature of nicotine binding to rat brain P2 fraction. Pharmacology, biochemistry, and behavior. vol 20. issue 6. 1984-08-31. PMID:6463074. |
thus while only (+)- and (-)-nicotine interacted with the very high affinity site, acetylcholine, atropine, mecamylamine, lobeline, carbachol, (+)-nicotine and (-)-nicotine enhanced the binding of (+/-)-[3h]nicotine and cytisine, anabasine, cotinine and choline selectively inhibited binding at the high affinity site. |
1984-08-31 |
2023-08-12 |
rat |
| B G Livett, P Boks. Receptors and receptor modulation in cultured chromaffin cells. Canadian journal of physiology and pharmacology. vol 62. issue 4. 1984-08-15. PMID:6203633. |
with regard to (1), substance p inhibited the secretion of catecholamines and atp evoked by acetylcholine or nicotine but not that evoked by k+ or veratridine, nor did substance p by itself affect secretion. |
1984-08-15 |
2023-08-12 |
cattle |
| B G Livett, P Boks. Receptors and receptor modulation in cultured chromaffin cells. Canadian journal of physiology and pharmacology. vol 62. issue 4. 1984-08-15. PMID:6203633. |
with regard to (2), substance p (greater than 5 x 10(-6) m) completely protected against desensitization of catecholamine release produced by acetylcholine (greater than 10(-4) m) or nicotine (greater than 2.5 x 10(-6) m) with no effect on k+-induced desensitization. |
1984-08-15 |
2023-08-12 |
cattle |
| L Todorov, M Papasov. Neurotransmitter interactions in smooth muscles from cat internal anal sphincter (in vitro experiments). Acta physiologica et pharmacologica Bulgarica. vol 10. issue 1. 1984-08-07. PMID:6146240. |
the ias relaxation induced by acetylcholine and nicotine is not associated with adrenergic mechanisms; it is assumed to be the result of a release of noncholinergic, nonadrenergic inhibitory neurotransmitter by means of presynaptic postganglionic cholinergic receptors. |
1984-08-07 |
2023-08-12 |
cat |