| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C T Su, C P Tang, C Ma, Y S Shih, C Y Liu, M T W. Quantitative structure-activity relationships and possible mechanisms of action of bispyridinium oximes as antidotes against pinacolyl methylphosphonofluoridate. Fundamental and applied toxicology : official journal of the Society of Toxicology. vol 3. issue 4. 1983-12-20. PMID:6628889. |
x-ray structural analysis showed that these oximes possessed structural similarity to nicotine and acetylcholine of nicotinic conformation. |
1983-12-20 |
2023-08-12 |
Not clear |
| P Onali, M C Olianas, J P Schwartz, E Cost. Involvement of a high-affinity GTPase in the inhibitory coupling of striatal muscarinic receptors to adenylate cyclase. Molecular pharmacology. vol 24. issue 3. 1983-12-17. PMID:6138702. |
acetylcholine (ach), but not nicotine, increases the vmax of the high-affinity gtpase, and the stimulatory effect is antagonized by atropine but not by d-tubocurarine. |
1983-12-17 |
2023-08-12 |
rat |
| M Levine, A Asher, H Pollard, O Zinde. Ascorbic acid and catecholamine secretion from cultured chromaffin cells. The Journal of biological chemistry. vol 258. issue 21. 1983-12-17. PMID:6630224. |
ascorbic acid was found to be secreted from cultured bovine adrenal chromaffin cells coincidentally with catecholamines using a variety of secretagogues, including veratridine, nicotine, acetylcholine, and potassium chloride. |
1983-12-17 |
2023-08-12 |
cattle |
| R D Schwartz, K J Kella. [3H]acetylcholine binding sites in brain. Effect of disulfide bond modification. Molecular pharmacology. vol 24. issue 3. 1983-12-17. PMID:6633505. |
in addition, pretreatment of cortical homogenates with acetylcholine or nicotine did not alter the effects of dithiothreitol on [3h] acetylcholine binding, suggesting that the disulfide bonds which are critical for [3h] acetylcholine binding are not located directly at the recognition site. |
1983-12-17 |
2023-08-12 |
rat |
| K Sumikawa, T Matsumoto, Y Amenomori, H Hirano, Y Amakat. Selective actions of intravenous anesthetics on nicotinic- and muscarinic-receptor-mediated responses of the dog adrenal medulla. Anesthesiology. vol 59. issue 5. 1983-12-17. PMID:6638547. |
log-probit dose-response curves of the inhibitory effects of the anesthetics on the catecholamine releases induced by acetylcholine, nicotine, and muscarine were determined. |
1983-12-17 |
2023-08-12 |
dog |
| S P Wilson, N Kirshne. Effects of ascorbic acid, dexamethasone, and insulin on the catecholamine and opioid peptide stores of cultured adrenal medullary chromaffin cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 3. issue 10. 1983-11-23. PMID:6352871. |
chromaffin cells were also tested for the ability to resynthesize their catecholamine and opioid peptide stores following depletion as the result of secretion evoked by acetylcholine or nicotine. |
1983-11-23 |
2023-08-12 |
cattle |
| P B Bradley, A P Luc. Cholinoceptive properties of respiratory neurones in the rat medulla. Neuropharmacology. vol 22. issue 7. 1983-11-23. PMID:6621815. |
the effects of iontophoretically applied acetylcholine, the acetylcholine agonists nicotine and muscarine, and the antagonists atropine, dihydro-beta-erythroidine (dh beta e) and mecamylamine, together with the excitatory amino acids, glutamate and d,l-homocysteic acid (dlh) were examined on the activity of respiratory-related neurones in the rat medulla and were compared with effects on non-respiratory brain stem neurones. |
1983-11-23 |
2023-08-12 |
rat |
| A Nordberg, A Sundwal. Pharmacodynamic effects of nicotine and acetylcholine biosynthesis in mouse brain. Acta pharmacologica et toxicologica. vol 52. issue 5. 1983-09-23. PMID:6880769. |
pharmacodynamic effects of nicotine and acetylcholine biosynthesis in mouse brain. |
1983-09-23 |
2023-08-12 |
mouse |
| A Nordberg, A Sundwal. Pharmacodynamic effects of nicotine and acetylcholine biosynthesis in mouse brain. Acta pharmacologica et toxicologica. vol 52. issue 5. 1983-09-23. PMID:6880769. |
when a tracer dose of labelled choline (3h-ch) was given to mice treated with nicotine (4 mg/kg) a marked increase (+100%) in the biosynthesis of labelled acetylcholine (ach) in the striatum was found when the animals were killed by decapitation. |
1983-09-23 |
2023-08-12 |
mouse |
| D V Priola, M B Curtis, C Anagnostelis, E Martine. Altered nicotinic sensitivity of AV node in surgically denervated canine hearts. The American journal of physiology. vol 245. issue 1. 1983-08-11. PMID:6869561. |
the responses of normal and cardiac-denervated (dnv) dogs to acetylcholine (ach) and nicotine (nic) were examined to determine if the intrinsic cardiac nerves (icn) that modulate electrical conduction display denervation supersensitivity. |
1983-08-11 |
2023-08-12 |
Not clear |
| L Kerkerian, A Nieoullo. Effects of acetylcholine on sodium-dependent high-affinity glutamate transport in rat striatal homogenates. Journal of neurochemistry. vol 40. issue 5. 1983-05-27. PMID:6131939. |
incubation of rat striatal tissue in the presence of acetylcholine, carbachol, oxotremorine, or nicotine results in a significant decrease in the sodium-dependent high-affinity glutamate uptake (hagu). |
1983-05-27 |
2023-08-12 |
rat |
| T D White, M Al-Humayy. Acetylcholine releases ATP from varicosities isolated from guinea pig myenteric plexus. Journal of neurochemistry. vol 40. issue 4. 1983-05-05. PMID:6403667. |
in a previous study, acetylcholine and nicotine released atp from isolated myenteric varicosities, whereas the muscarinic agonist bethanechol did not. |
1983-05-05 |
2023-08-12 |
Not clear |
| T D White, M Al-Humayy. Acetylcholine releases ATP from varicosities isolated from guinea pig myenteric plexus. Journal of neurochemistry. vol 40. issue 4. 1983-05-05. PMID:6403667. |
d-tubocurarine competitively antagonized the release of atp by either acetylcholine or nicotine. |
1983-05-05 |
2023-08-12 |
Not clear |
| T D White, M Al-Humayy. Acetylcholine releases ATP from varicosities isolated from guinea pig myenteric plexus. Journal of neurochemistry. vol 40. issue 4. 1983-05-05. PMID:6403667. |
tetrodotoxin slightly but significantly reduced atp release induced by acetylcholine or nicotine, indicating some involvement of na+ channels in the release process. |
1983-05-05 |
2023-08-12 |
Not clear |
| R D Schwartz, K J Kella. Nicotinic cholinergic receptor binding sites in the brain: regulation in vivo. Science (New York, N.Y.). vol 220. issue 4593. 1983-04-21. PMID:6828889. |
however, after repeated administration of nicotine for 10 days, binding of tritiated acetylcholine in the cortex was increased. |
1983-04-21 |
2023-08-12 |
rat |
| R D Schwartz, K J Kella. Nicotinic cholinergic receptor binding sites in the brain: regulation in vivo. Science (New York, N.Y.). vol 220. issue 4593. 1983-04-21. PMID:6828889. |
saturation analysis of tritiated acetylcholine binding in the cortices of rats treated with diisopropyl fluorophosphate or nicotine indicated that the number of binding sites decreased and increased, respectively, while the affinity of the sites was unaltered. |
1983-04-21 |
2023-08-12 |
rat |
| M de Lourdes Arruzazabala, R G Alvare. Further studies on the effects of disodium cromoglycate on guinea pig ileum. Agents and actions. vol 12. issue 5-6. 1983-04-07. PMID:6819770. |
furthermore, dscg inhibits significantly the guinea pig ileum contractions induced by nicotine and also those induced by histamine and acetylcholine on ileum denervated by cooling. |
1983-04-07 |
2023-08-12 |
Not clear |
| R Corder, D F Mason, D Perrett, P J Lowry, V Clement-Jones, E A Linton, G M Besser, L H Ree. Simultaneous release of neurotensin, somatostatin, enkephalins and catecholamines from perfused cat adrenal glands. Neuropeptides. vol 3. issue 1. 1983-03-11. PMID:6130490. |
using isolated retrogradely perfused cat adrenal glands the secretory responses to acetylcholine (ach), nicotine and potassium ions (k+) were studied. |
1983-03-11 |
2023-08-12 |
cat |
| Y Lamour, P Dutar, A Jober. Spread of acetylcholine sensitivity in the neocortex following lesion of the nucleus basalis. Brain research. vol 252. issue 2. 1983-03-11. PMID:7150959. |
neuronal responses to the iontophoretic application of acetylcholine, carbachol and nicotine were studied in rats, 2 or 3 weeks following bilateral lesions of the nucleus basalis region, and compared to those obtained in normal animals. |
1983-03-11 |
2023-08-12 |
rat |
| Y Lamour, P Dutar, A Jober. Spread of acetylcholine sensitivity in the neocortex following lesion of the nucleus basalis. Brain research. vol 252. issue 2. 1983-03-11. PMID:7150959. |
furthermore, the laminar distribution of the responses to acetylcholine and the proportion of responses to carbachol and nicotine were also modified. |
1983-03-11 |
2023-08-12 |
rat |