| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J P Huidobro-Toro, B Fore. Dual agonist-antagonist effects of 5-hydroxytryptamine (5-HT) in the guinea pig ileum: evidence for a selective receptor desensitization effect. European journal of pharmacology. vol 61. issue 4. 1980-07-12. PMID:6102916. |
5-ht did not antagonize the effects of acetylcholine, dimethylphenylpiperazinium, nicotine, histamine, prostaglandin e2, substance p or angiotensin ii. |
1980-07-12 |
2023-08-12 |
Not clear |
| M Göthert, U Dührsen, J M Rieckesman. Ethanol, anaesthetics and other lipophilic drugs preferentially inhibit 5-hydroxytryptamine- and acetylcholine-induced noradrenaline release from sympathetic nerves. Archives internationales de pharmacodynamie et de therapie. vol 242. issue 2. 1980-06-25. PMID:543753. |
there was a good correlation between the negative logarithms of the ic50 values of these compounds and the longarithms of their membrane/buffer partition coefficients (r = 0.993).--similar to our our previous results with aliphatic alcohols and inhalation anaesthetics, we found that the noradrenaline output induced by activation of the nicotine receptors with acetylcholine was also decreased by barbiturates, propanidid, ketamine, phenytoin and chlorpromazine in a concentration-dependent manner. |
1980-06-25 |
2023-08-11 |
rabbit |
| J T Schmidt, J A Freema. Electrophysiologic evidence that retinotectal synaptic transmission in the goldfish is nicotinic cholinergic. Brain research. vol 187. issue 1. 1980-05-30. PMID:6244064. |
atropine, a muscarinic antagonist, had only a slight effect even at 10-3 m. five nicotinic agonists tested also decremented synaptic responses: nicotine (10-5 m), carbamylcholine (10-4 m), acetylcholine (10-4 m), succinyl choline (10-4 m) and decamethonium (10-3 m), presumably via cellular depolarization and receptor desensitization. |
1980-05-30 |
2023-08-12 |
Not clear |
| S Yamada, E Hayash. Effects of surugatoxin on adrenergically innervated tissues. Japanese journal of pharmacology. vol 29. issue 2. 1980-05-23. PMID:537251. |
the contractile response of the vas deferens to nicotine, dmpp and hypogastric nerve stimulation was markedly reduced by sgtx (1, 10 mum), whereas that to noradrenaline, acetylcholine and transmural stimulation was not affected. |
1980-05-23 |
2023-08-11 |
Not clear |
| R L Rodgers, J I Moore, K R Hornbroo. Comparison of the cardiostimulatory effects of acetylcholine and nicotine on the working guinea-pig heart. Naunyn-Schmiedeberg's archives of pharmacology. vol 310. issue 2. 1980-04-26. PMID:231210. |
comparison of the cardiostimulatory effects of acetylcholine and nicotine on the working guinea-pig heart. |
1980-04-26 |
2023-08-11 |
Not clear |
| R L Rodgers, J I Moore, K R Hornbroo. Comparison of the cardiostimulatory effects of acetylcholine and nicotine on the working guinea-pig heart. Naunyn-Schmiedeberg's archives of pharmacology. vol 310. issue 2. 1980-04-26. PMID:231210. |
the isolated working guinea-pig heart was used to compare the cardiostimulatory effects of acetylcholine and nicotine observed in the presence of atropine. |
1980-04-26 |
2023-08-11 |
Not clear |
| R L Rodgers, J I Moore, K R Hornbroo. Comparison of the cardiostimulatory effects of acetylcholine and nicotine on the working guinea-pig heart. Naunyn-Schmiedeberg's archives of pharmacology. vol 310. issue 2. 1980-04-26. PMID:231210. |
hexamethonium treatment abolished the responses to acetylcholine and to nicotine. |
1980-04-26 |
2023-08-11 |
Not clear |
| R L Rodgers, J I Moore, K R Hornbroo. Comparison of the cardiostimulatory effects of acetylcholine and nicotine on the working guinea-pig heart. Naunyn-Schmiedeberg's archives of pharmacology. vol 310. issue 2. 1980-04-26. PMID:231210. |
the results support the view that the cardiostimulatory effects of acetylcholine are due entirely to endogenous catecholamine release, but that the effects of nicotine may involve an additional action. |
1980-04-26 |
2023-08-11 |
Not clear |
| V V Frolkis, V G Shevtchuk, N S Verkhratsky, A S Stupina, S M Karpova, T Y Lakiz. Mechanisms of neurohumoral regulation of heart function in aging. Experimental aging research. vol 5. issue 5. 1980-03-24. PMID:42543. |
the intensity of acetylcholine and norepinephrine synthesis was decreased in old age, the transmitter metabolism in various parts of the heart was not uniformly altered, the sensitivity of epicardial chemoreceptors to nicotine, veratrum, acetylcholine was increased. |
1980-03-24 |
2023-08-11 |
rat |
| S Yamada, H Okudaira, E Hayash. An alteration in sensitivity to cholinergic agents on guinea-pig ilea and atria after repeated administration of an organophosphate and an antagonism by a carbamate. Archives internationales de pharmacodynamie et de therapie. vol 241. issue 1. 1980-03-24. PMID:526070. |
the effect of 4-methylthiophenyl dipropylphosphate (propaphos, organophosphorus insecticide) and 2-sec-butylphenyl-n-methylcarbamate (bpmc, carbamate insecticide) on the sensitivity to the effects of acetylcholine (ach), carbachol (cch) and nicotine was investigated on guinea-pig isolated ilea and atria. |
1980-03-24 |
2023-08-11 |
Not clear |
| J P Famaey, J Fontaine, I Seaman, J Reus. The effects of antiinflammatory steroids on the response of the guinea-pig isolated ileum to acetylcholine, histamine, nicotine, 5-hydroxytryptamine and electrical stimulation. Naunyn-Schmiedeberg's archives of pharmacology. vol 309. issue 2. 1980-03-17. PMID:522904. |
the effects of antiinflammatory steroids on the response of the guinea-pig isolated ileum to acetylcholine, histamine, nicotine, 5-hydroxytryptamine and electrical stimulation. |
1980-03-17 |
2023-08-11 |
Not clear |
| J P Famaey, J Fontaine, I Seaman, J Reus. The effects of antiinflammatory steroids on the response of the guinea-pig isolated ileum to acetylcholine, histamine, nicotine, 5-hydroxytryptamine and electrical stimulation. Naunyn-Schmiedeberg's archives of pharmacology. vol 309. issue 2. 1980-03-17. PMID:522904. |
at 40 microgram/ml they also reversibly inhibited contractions elicited by acetylcholine, histamine nicotine and 5-hydroxytryptamine. |
1980-03-17 |
2023-08-11 |
Not clear |
| T L Sahley, G G Berntso. Antinociceptive effects of central and systemic administrations of nicotine in the rat. Psychopharmacology. vol 65. issue 3. 1980-02-28. PMID:117500. |
the present results also support the suggestion that nicotine may selectively reduce sensitivity to certain classes of pain stimuli, perhaps through a central releasing action on acetylcholine. |
1980-02-28 |
2023-08-11 |
rat |
| I H Ulus, R J Wurtma. Selective response of rat peripheral sympathetic nervous system to various stimuli. The Journal of physiology. vol 293. 1980-01-24. PMID:41093. |
choline administration increased tyrosine hydroxylase activity in all four tissues, probably by increasing the release of acetylcholine from preganglionic sympathetic neurones that synapse on catecholamine-producing ganglion and chromaffin cells; carbachol and nicotine had similar effects.3. |
1980-01-24 |
2023-08-11 |
rat |
| J Chester, T L Lentz, J K Marquis, H G Mautne. Localization of horseradish peroxidase-alpha-bungarotoxin binding in crustacean axonal membrane vesicles and intact axons. Proceedings of the National Academy of Sciences of the United States of America. vol 76. issue 7. 1979-12-18. PMID:291022. |
these plasma membrane vesicles have previously been shown to exhibit saturable binding of [3h]nicotine and [3h]acetylcholine. |
1979-12-18 |
2023-08-11 |
lobster |
| F Schneeweiss, D Naquira, K Rosenheck, A S Schneide. Cholinergic stimulants and excess potassium ion increase the fluidity of plasma membranes isolated from adrenal chromaffin cells. Biochimica et biophysica acta. vol 555. issue 3. 1979-12-18. PMID:486462. |
previous incubation with either acetylcholine (0.5 mm) or nicotine (50 microm) produced further fluidization, the extent of which depended on the presence of added ca2+ (2.2 mm). |
1979-12-18 |
2023-08-11 |
cattle |
| J C Buckingham, J R Hodge. Hypothalamic receptors influencing the secretion of corticotrophin releasing hormone in the rat. The Journal of physiology. vol 290. issue 2. 1979-10-24. PMID:38334. |
acetylcholine, nicotine and bethanechol increased, in a dose-related manner, hypothalamic crh release and content but the maximal responses to bethanechol or nicotine were less than those to acetylcholine.3. |
1979-10-24 |
2023-08-11 |
rat |
| D E Burleigh, A D'Mello, A G Park. Responses of isolated human internal anal sphincter to drugs and electrical field stimulation. Gastroenterology. vol 77. issue 3. 1979-09-27. PMID:456843. |
hexamethonium in concentrations sufficient to block relaxations to 1,1-dimethyl-4-phenylpiperazinium iodide or nicotine had no effect on relaxations due to acetylcholine, thereby indicating that acetylcholine was acting on muscarinic receptors. |
1979-09-27 |
2023-08-11 |
human |
| C D Sladek, R J Joyn. Angiotensin stimulation of vasopressin release from the rat hypothalamo-neurohypophyseal system in organ culture. Endocrinology. vol 104. issue 1. 1979-09-01. PMID:446341. |
saralasin did not interfere with stimulation of vp release by acetylcholine or nicotine. |
1979-09-01 |
2023-08-11 |
rat |
| C D Sladek, R J Joyn. Characterization of cholinergic control of vasopressin release by the organ-cultured rat hypothalamo-neurohypophyseal system. Endocrinology. vol 104. issue 3. 1979-07-25. PMID:436724. |
acetylcholine and nicotine stimulated vasopressin (vp) release from the organ-cultured rat hypothalamo-neurohypophyseal system (hns). |
1979-07-25 |
2023-08-11 |
rat |