| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O Barochovsky, H F Bradfor. Modulation of dopamine release from neuron-enriched tissue cultures by cholinergic agents. Journal of neurochemistry. vol 48. issue 3. 1987-03-19. PMID:3806105. |
monolayer and aggregated neuron-enriched cultures were maintained for 17 days in vitro [3h]dopamine basal outflow was enhanced by acetylcholine, nicotine, and atropine and was unaffected by oxotremorine, hexamethonium, and d-tubocurarine. |
1987-03-19 |
2023-08-11 |
rat |
| A Nordberg, B Winbla. Reduced number of [3H]nicotine and [3H]acetylcholine binding sites in the frontal cortex of Alzheimer brains. Neuroscience letters. vol 72. issue 1. 1987-03-04. PMID:3808458. |
reduced number of [3h]nicotine and [3h]acetylcholine binding sites in the frontal cortex of alzheimer brains. |
1987-03-04 |
2023-08-11 |
human |
| A Nordberg, B Winbla. Reduced number of [3H]nicotine and [3H]acetylcholine binding sites in the frontal cortex of Alzheimer brains. Neuroscience letters. vol 72. issue 1. 1987-03-04. PMID:3808458. |
nicotinic cholinergic receptors were measured in human frontal cortex using [3h]nicotine and [3h]acetylcholine (in the presence of atropine) as receptor ligands. |
1987-03-04 |
2023-08-11 |
human |
| A Nordberg, B Winbla. Reduced number of [3H]nicotine and [3H]acetylcholine binding sites in the frontal cortex of Alzheimer brains. Neuroscience letters. vol 72. issue 1. 1987-03-04. PMID:3808458. |
a parallel marked reduction in number of [3h]nicotine (52%; p less than 0.01) and [3h]acetylcholine (-55%; p less than 0.05) binding was found in the frontal cortex of alzheimer brains (ad/sdat) when compared to age-matched control brains. |
1987-03-04 |
2023-08-11 |
human |
| M Bezeková, V Baue. The effects of some carbamate local anaesthetics on the guinea-pig ileum. Drugs under experimental and clinical research. vol 12. issue 9-10. 1987-02-13. PMID:3792205. |
contractions of the ileum were evoked by transmural stimulation, nicotine, acetylcholine, noradrenaline, histamine, k+ and ba++. |
1987-02-13 |
2023-08-11 |
Not clear |
| P J Whitehouse, K S A. Cholinergic receptors in aging and Alzheimer's disease. Progress in neuro-psychopharmacology & biological psychiatry. vol 10. issue 3-5. 1987-02-06. PMID:3541056. |
our recent studies using [3h] acetylcholine and [3h] nicotine have demonstrated a reduction in ncr in ad. |
1987-02-06 |
2023-08-11 |
Not clear |
| F Okwuasaba, C Ejike, O Parr. Skeletal muscle relaxant properties of the aqueous extract of Portulaca oleracea. Journal of ethnopharmacology. vol 17. issue 2. 1987-02-04. PMID:3796017. |
ca2+-free tyrode's solution and edta (1.25 x 10(-3) g/ml) potentiated extract-induced depression of twitch tension to ms. on the rectus abdominis, contractures induced by nicotinic agonists (acetylcholine, 3-500 x 10(-7) m; carbachol, 5-500 x 10(-7) m and nicotine, 5-500 x 10(-8) m) were significantly attenuated and/or abolished by the extract (5-10 x 10(-3) g/ml). |
1987-02-04 |
2023-08-11 |
rat |
| M R Boarder, D Marriott, M Adam. Stimulus secretion coupling in cultured chromaffin cells. Dependency on external sodium and on dihydropyridine-sensitive calcium channels. Biochemical pharmacology. vol 36. issue 1. 1987-01-28. PMID:2432901. |
stimulus secretion in response to acetylcholine (or nicotine) in adrenal chromaffin cells involves calcium influx and is tetrodotoxin insensitive. |
1987-01-28 |
2023-08-11 |
cattle |
| M Jay, S Kojima, M N Gillespi. Nicotine potentiates superoxide anion generation by human neutrophils. Toxicology and applied pharmacology. vol 86. issue 3. 1987-01-21. PMID:3024359. |
the potentiating effect of nicotine was not attenuated by either atropine or hexamethonium nor was it mimicked by acetylcholine, suggesting involvement of noncholinergic receptors or a membrane-fluidizing effect of the alkaloid. |
1987-01-21 |
2023-08-11 |
human |
| K W Brocklehurst, H B Pollar. Synergistic actions of Ca2+ and the phorbol ester TPA on K+-induced catecholamine release from bovine adrenal chromaffin cells. Biochemical and biophysical research communications. vol 140. issue 3. 1986-12-18. PMID:3778497. |
this effect of tpa was not reproduced when the secretagogues acetylcholine, nicotine, or veratrine were substituted for high k+. |
1986-12-18 |
2023-08-11 |
cattle |
| J T Cheng, K Shinozuk. Picric acid functions as a releaser of [14C]acetylcholine in isolated ileal synaptosomal preparations of guinea-pig. Journal of autonomic pharmacology. vol 6. issue 3. 1986-12-16. PMID:3021774. |
indomethacin, at a concentration (1 microm) effective in inhibiting the synthesis of prostaglandins, reduced the release of acetylcholine evoked by picric acid or nicotine, but did not affect the responses to high k-depolarization or electrical field stimulation. |
1986-12-16 |
2023-08-11 |
Not clear |
| M J Marks, J A Stitzel, E Romm, J M Wehner, A C Collin. Nicotinic binding sites in rat and mouse brain: comparison of acetylcholine, nicotine, and alpha-bungarotoxin. Molecular pharmacology. vol 30. issue 5. 1986-12-10. PMID:3534542. |
nicotinic binding sites in rat and mouse brain: comparison of acetylcholine, nicotine, and alpha-bungarotoxin. |
1986-12-10 |
2023-08-11 |
mouse |
| M J Marks, J A Stitzel, E Romm, J M Wehner, A C Collin. Nicotinic binding sites in rat and mouse brain: comparison of acetylcholine, nicotine, and alpha-bungarotoxin. Molecular pharmacology. vol 30. issue 5. 1986-12-10. PMID:3534542. |
the properties of the binding sites for radiolabeled acetylcholine (measured in the presence of atropine), nicotine, and alpha-bungarotoxin were compared in brain tissue prepared from both rat and mouse. |
1986-12-10 |
2023-08-11 |
mouse |
| M J Marks, J A Stitzel, E Romm, J M Wehner, A C Collin. Nicotinic binding sites in rat and mouse brain: comparison of acetylcholine, nicotine, and alpha-bungarotoxin. Molecular pharmacology. vol 30. issue 5. 1986-12-10. PMID:3534542. |
the binding sites for acetylcholine and nicotine were affected identically for all measurements, whereas the binding site for alpha-bungarotoxin was affected in a manner different from that for the other two ligands. |
1986-12-10 |
2023-08-11 |
mouse |
| M J Marks, J A Stitzel, E Romm, J M Wehner, A C Collin. Nicotinic binding sites in rat and mouse brain: comparison of acetylcholine, nicotine, and alpha-bungarotoxin. Molecular pharmacology. vol 30. issue 5. 1986-12-10. PMID:3534542. |
although the regional distribution of nicotine and acetylcholine binding differed between rat and mouse brain, other properties of this binding site were very similar between the two species. |
1986-12-10 |
2023-08-11 |
mouse |
| M J Marks, J A Stitzel, E Romm, J M Wehner, A C Collin. Nicotinic binding sites in rat and mouse brain: comparison of acetylcholine, nicotine, and alpha-bungarotoxin. Molecular pharmacology. vol 30. issue 5. 1986-12-10. PMID:3534542. |
the results are consistent with the proposal that acetylcholine and nicotine bind to the same sites in both rat and mouse brain, whereas alpha-bungarotoxin binds to different sites. |
1986-12-10 |
2023-08-11 |
mouse |
| T M Egan, R A Nort. Actions of acetylcholine and nicotine on rat locus coeruleus neurons in vitro. Neuroscience. vol 19. issue 2. 1986-12-04. PMID:2430232. |
actions of acetylcholine and nicotine on rat locus coeruleus neurons in vitro. |
1986-12-04 |
2023-08-11 |
rat |
| T M Egan, R A Nort. Actions of acetylcholine and nicotine on rat locus coeruleus neurons in vitro. Neuroscience. vol 19. issue 2. 1986-12-04. PMID:2430232. |
intracellular recordings were made from neurons of the rat locus coeruleus in a slice of tissue cut from the pons and superfused in vitro at 37 degrees c. both acetylcholine, in the presence of a muscarinic antagonist, and nicotine depolarized locus coeruleus neurons and increased the rate of action potential discharge. |
1986-12-04 |
2023-08-11 |
rat |
| T M Egan, R A Nort. Actions of acetylcholine and nicotine on rat locus coeruleus neurons in vitro. Neuroscience. vol 19. issue 2. 1986-12-04. PMID:2430232. |
these effects persisted in a superfusing solution that contained no calcium ions and a raised magnesium ion concentration; because such solutions block synaptic potentials in the locus coeruleus, it was concluded that the acetylcholine and nicotine acted directly on the cell from which the recording was made. |
1986-12-04 |
2023-08-11 |
rat |
| T M Egan, R A Nort. Actions of acetylcholine and nicotine on rat locus coeruleus neurons in vitro. Neuroscience. vol 19. issue 2. 1986-12-04. PMID:2430232. |
recordings of membrane current showed that acetylcholine and nicotine caused a net inward current, the amplitude of which increased linearly as the membrane potential was changed from -40 to -90 mv; the extrapolated reversal potential was about -20 mv (extracellular potassium concentration was 2.5 mmol/l). |
1986-12-04 |
2023-08-11 |
rat |