| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Maggio, M Riva, F Vaglini, F Fornai, G Racagni, G U Corsin. Striatal increase of neurotrophic factors as a mechanism of nicotine protection in experimental parkinsonism. Journal of neural transmission (Vienna, Austria : 1996). vol 104. issue 10. 1998-04-29. PMID:9503263. |
as fgf-2 and bdnf have been reported to be neuroprotective for dopaminergic cells, our data indicate that the increase in neurotrophic factors is a possible mechanism by which (-)nicotine protects from experimental parkinsonisms. |
1998-04-29 |
2023-08-12 |
mouse |
| J A Gray, P M Moran, G Grigoryan, S L Peters, A M Young, M H Josep. Latent inhibition: the nucleus accumbens connection revisited. Behavioural brain research. vol 88. issue 1. 1998-02-04. PMID:9401705. |
new evidence in support of this hypothesis is presented or reviewed here, showing that: (1) intra-accumbens injection of haloperidol at the time of conditioning potentiates li; (2) destruction of dopaminergic terminals in the nucleus accumbens potentiates li; (3) intra-accumbens haloperidol reverses the blockade of li caused by systemic nicotine; (4) intra-accumbens haloperidol reverses the blockade of li caused by systemic amphetamine; (5) after a single systemic injection of amphetamine (insufficient on its own to block li), a subsequent intra-accumbens injection of amphetamine at the time of conditioning blocks li; and (6) intra-accumbens (like systemic) amphetamine administered 15 min before conditioning, without prior systemic amphetamine, failed to block li. |
1998-02-04 |
2023-08-12 |
human |
| M R Picciotto, M Zoli, R Rimondini, C Léna, L M Marubio, E M Pich, K Fuxe, J P Changeu. Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine. Nature. vol 391. issue 6663. 1998-01-22. PMID:9428762. |
using patch-clamp recording, we show that mesencephalic dopaminergic neurons from mice without the beta2 subunit no longer respond to nicotine, and that self-administration of nicotine is attenuated in these mutant mice. |
1998-01-22 |
2023-08-12 |
mouse |
| S Ivanová, A J Greensha. Nicotine-induced decreases in VTA electrical self-stimulation thresholds: blockade by haloperidol and mecamylamine but not scopolamine or ondansetron. Psychopharmacology. vol 134. issue 2. 1998-01-09. PMID:9399383. |
these data are consistent with the proposal that repeated daily injections of nicotine positively effect a mesolimbic dopaminergic substrate of reward. |
1998-01-09 |
2023-08-12 |
Not clear |
| M Nisell, G G Nomikos, K Chergui, P Grillner, T H Svensso. Chronic nicotine enhances basal and nicotine-induced Fos immunoreactivity preferentially in the medial prefrontal cortex of the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 17. issue 3. 1998-01-08. PMID:9272482. |
these results suggest that the regionally selective effect of nicotine challenge on fli is due to enhanced dopaminergic transmission, mediated via stimulation of d1 receptors. |
1998-01-08 |
2023-08-12 |
rat |
| I M Maisonneuve, G L Mann, C R Deibel, S D Glic. Ibogaine and the dopaminergic response to nicotine. Psychopharmacology. vol 129. issue 3. 1997-11-19. PMID:9084063. |
ibogaine and the dopaminergic response to nicotine. |
1997-11-19 |
2023-08-12 |
rat |
| K Muneoka, T Ogawa, K Kamei, S Muraoka, R Tomiyoshi, Y Mimura, H Kato, M R Suzuki, M Takigaw. Prenatal nicotine exposure affects the development of the central serotonergic system as well as the dopaminergic system in rat offspring: involvement of route of drug administrations. Brain research. Developmental brain research. vol 102. issue 1. 1997-11-19. PMID:9298240. |
prenatal nicotine exposure affects the development of the central serotonergic system as well as the dopaminergic system in rat offspring: involvement of route of drug administrations. |
1997-11-19 |
2023-08-12 |
rat |
| P A Crooks, L P Dwoski. Contribution of CNS nicotine metabolites to the neuropharmacological effects of nicotine and tobacco smoking. Biochemical pharmacology. vol 54. issue 7. 1997-11-13. PMID:9353128. |
the reinforcing and locomotor stimulant effects of nicotine have been suggested to be the result of activation of cns dopaminergic systems, and nicotine-induced modulation of dopaminergic neurotransmission has been studied in detail. |
1997-11-13 |
2023-08-12 |
Not clear |
| G F Koob, E J Nestle. The neurobiology of drug addiction. The Journal of neuropsychiatry and clinical neurosciences. vol 9. issue 3. 1997-10-16. PMID:9276849. |
nicotine's reinforcing effects may involve both dopaminergic and opioid peptidergic systems. |
1997-10-16 |
2023-08-12 |
Not clear |
| J E Rose, W A Corrigal. Nicotine self-administration in animals and humans: similarities and differences. Psychopharmacology. vol 130. issue 1. 1997-07-18. PMID:9089846. |
the mesolimbic dopamine pathway has been implicated in nicotine reward based on animal studies, and research with humans suggests a role for dopaminergic processes as well. |
1997-07-18 |
2023-08-12 |
human |
| J E Rose, W A Corrigal. Nicotine self-administration in animals and humans: similarities and differences. Psychopharmacology. vol 130. issue 1. 1997-07-18. PMID:9089846. |
however, dopaminergic blockade appears to increase cigarette smoking behavior in humans, while in animals nicotine self-administration is attenuated. |
1997-07-18 |
2023-08-12 |
human |
| J N Wilkin. Pharmacotherapy of schizophrenia patients with comorbid substance abuse. Schizophrenia bulletin. vol 23. issue 2. 1997-07-15. PMID:9165632. |
d2 dopaminergic receptor antagonists may indirectly block the drive for stimulant and nicotine use, while opioid antagonists appear to reduce the drive to use alcohol. |
1997-07-15 |
2023-08-12 |
Not clear |
| B Ferger, K Kuschinsk. Biochemical studies support the assumption that dopamine plays a minor role in the EEG effects of nicotine. Psychopharmacology. vol 129. issue 2. 1997-06-16. PMID:9040126. |
this seemed surprising, since nicotine is known to enhance dopaminergic neurotransmission in the basal ganglia. |
1997-06-16 |
2023-08-12 |
rat |
| D L Marshall, P H Redfern, S Wonnacot. Presynaptic nicotinic modulation of dopamine release in the three ascending pathways studied by in vivo microdialysis: comparison of naive and chronic nicotine-treated rats. Journal of neurochemistry. vol 68. issue 4. 1997-04-28. PMID:9084421. |
we have characterised the effect of nicotine, locally applied via a microdialysis probe, on dopamine release from the terminal regions of three ascending dopaminergic pathways in conscious, freely moving rats. |
1997-04-28 |
2023-08-12 |
rat |
| S R Pagliusi, M Tessari, S DeVevey, C Chiamulera, E M Pic. The reinforcing properties of nicotine are associated with a specific patterning of c-fos expression in the rat brain. The European journal of neuroscience. vol 8. issue 11. 1997-03-17. PMID:8950089. |
the results suggest the involvement of restricted terminal regions of the mesocorticolimbic dopaminergic system in the maintenance of nicotine self-administration. |
1997-03-17 |
2023-08-12 |
rat |
| P Netter, J Hennig, I S Roe. Serotonin and dopamine as mediators of sensation seeking behavior. Neuropsychobiology. vol 34. issue 3. 1997-03-04. PMID:8916073. |
the dopaminergic (da) response to a da agonist (lisuride) and antagonist (fluphenazine) was analyzed in a condition of smoking deprivation (study 3) using prl responses, emotional states, and behavioral measures of nicotine craving as dependent variables. |
1997-03-04 |
2023-08-12 |
human |
| Y K Fung, M J Schmid, T M Anderson, Y S La. Effects of nicotine withdrawal on central dopaminergic systems. Pharmacology, biochemistry, and behavior. vol 53. issue 3. 1997-01-15. PMID:8866966. |
effects of nicotine withdrawal on central dopaminergic systems. |
1997-01-15 |
2023-08-12 |
rat |
| R Erdman. [Nicotine in neuropsychiatric movement disorders]. Fortschritte der Neurologie-Psychiatrie. vol 64. issue 9. 1997-01-14. PMID:8991874. |
nicotine has various effects in the cns, especially in dopaminergic and cholinergic systems, relevant in pathophysiology of neuropsychiatric movement disorders. |
1997-01-14 |
2023-08-12 |
Not clear |
| M R Zarrindast, D Farzi. Nicotine attenuates naloxone-induced jumping behaviour in morphine-dependent mice. European journal of pharmacology. vol 298. issue 1. 1996-11-27. PMID:8867912. |
in addition, the modulatory role of dopaminergic, adrenergic and cholinergic mechanisms upon the effect of nicotine were investigated. |
1996-11-27 |
2023-08-12 |
mouse |
| M Garcia-Munoz, P Patino, S J Young, P M Grove. Effects of nicotine on dopaminergic nigrostriatal axons requires stimulation of presynaptic glutamatergic receptors. The Journal of pharmacology and experimental therapeutics. vol 277. issue 3. 1996-08-06. PMID:8667239. |
effects of nicotine on dopaminergic nigrostriatal axons requires stimulation of presynaptic glutamatergic receptors. |
1996-08-06 |
2023-08-12 |
rat |