| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y K Fung, Y S La. Chronic effects of nicotine on mesolimbic dopaminergic system in rats. Pharmacology, biochemistry, and behavior. vol 41. issue 1. 1992-04-02. PMID:1347177. |
chronic effects of nicotine on mesolimbic dopaminergic system in rats. |
1992-04-02 |
2023-08-11 |
rat |
| Y K Fung, Y S La. Chronic effects of nicotine on mesolimbic dopaminergic system in rats. Pharmacology, biochemistry, and behavior. vol 41. issue 1. 1992-04-02. PMID:1347177. |
the behavioral and biochemical effects of nicotine on the dopaminergic neuronal system in rat nucleus accumbens were examined. |
1992-04-02 |
2023-08-11 |
rat |
| D P Sachs, S J Leischo. Pharmacologic approaches to smoking cessation. Clinics in chest medicine. vol 12. issue 4. 1992-01-23. PMID:1747993. |
nicotine receptors in the locus coeruleus and the midbrain mesolimbic dopaminergic system activate both arousal state and enhance cognitive functioning (locus coeruleus) and activate the brain's "pleasure center" (mesolimbic system). |
1992-01-23 |
2023-08-11 |
Not clear |
| H Sershen, A Hashim, L Harsing, A Lajth. Chronic nicotine-induced changes in dopaminergic system: effect on behavioral response to dopamine agonist. Pharmacology, biochemistry, and behavior. vol 39. issue 2. 1991-11-26. PMID:1682953. |
the results suggest that chronic nicotine may induce changes in the dopaminergic system, which is reflected in altered behavioral response to a dopamine agonist. |
1991-11-26 |
2023-08-11 |
mouse |
| M F O'Neill, C T Dourish, S D Iverse. Evidence for an involvement of D1 and D2 dopamine receptors in mediating nicotine-induced hyperactivity in rats. Psychopharmacology. vol 104. issue 3. 1991-11-18. PMID:1833784. |
the effect appears to be mediated by central nicotine receptors, possibly located on dopaminergic neurons, and also requires the activation of both d1 and d2 dopamine receptors. |
1991-11-18 |
2023-08-11 |
rat |
| K M Smith, S N Mitchell, M H Josep. Effects of chronic and subchronic nicotine on tyrosine hydroxylase activity in noradrenergic and dopaminergic neurones in the rat brain. Journal of neurochemistry. vol 57. issue 5. 1991-11-15. PMID:1681034. |
effects of chronic and subchronic nicotine on tyrosine hydroxylase activity in noradrenergic and dopaminergic neurones in the rat brain. |
1991-11-15 |
2023-08-11 |
rat |
| K M Smith, S N Mitchell, M H Josep. Effects of chronic and subchronic nicotine on tyrosine hydroxylase activity in noradrenergic and dopaminergic neurones in the rat brain. Journal of neurochemistry. vol 57. issue 5. 1991-11-15. PMID:1681034. |
chronic nicotine (0.8 mg/kg by daily subcutaneous injection) over a 7 to 28-day period was found to increase the activity of tyrosine hydroxylase in predominantly noradrenergically innervated regions but not in dopaminergic projection areas. |
1991-11-15 |
2023-08-11 |
rat |
| K M Smith, S N Mitchell, M H Josep. Effects of chronic and subchronic nicotine on tyrosine hydroxylase activity in noradrenergic and dopaminergic neurones in the rat brain. Journal of neurochemistry. vol 57. issue 5. 1991-11-15. PMID:1681034. |
increases in tyrosine hydroxylase activity were observed in dopaminergic cell body regions only after nicotine treatment for 3 to 5 days. |
1991-11-15 |
2023-08-11 |
rat |
| Y K Fung, Y S La. Differential effects of chronic nicotine administration on dopaminergic receptor binding sites in rat nigrostriatal and mesolimbic regions. General pharmacology. vol 22. issue 1. 1991-07-24. PMID:2050279. |
differential effects of chronic nicotine administration on dopaminergic receptor binding sites in rat nigrostriatal and mesolimbic regions. |
1991-07-24 |
2023-08-11 |
rat |
| Y K Fung, Y S La. Differential effects of chronic nicotine administration on dopaminergic receptor binding sites in rat nigrostriatal and mesolimbic regions. General pharmacology. vol 22. issue 1. 1991-07-24. PMID:2050279. |
the effects of chronic (14 day) administration of nicotine (1.5 mg/kg/day) on the striatal and mesolimbic dopaminergic receptor binding sites were determined. |
1991-07-24 |
2023-08-11 |
rat |
| Y K Fung, Y S La. Differential effects of chronic nicotine administration on dopaminergic receptor binding sites in rat nigrostriatal and mesolimbic regions. General pharmacology. vol 22. issue 1. 1991-07-24. PMID:2050279. |
chronic administration of nicotine preferentially increased the number of dopaminergic receptor binding sites in the striatal, but not the mesolimbic area of rat brain. |
1991-07-24 |
2023-08-11 |
rat |
| M Quik, U Babu, T Audhya, G Goldstei. Evidence for thymopoietin and thymopoietin/alpha-bungarotoxin/nicotinic receptors within the brain. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 6. 1991-04-25. PMID:1848710. |
binding of 125i-labeled thymopoietin was displaced not only by unlabeled thymopoietin but also by alpha-bgt and the nicotinic receptor ligands d-tubocurarine and nicotine; various other receptor ligands (muscarinic, adrenergic, and dopaminergic) did not affect binding of 125i-labeled thymopoietin. |
1991-04-25 |
2023-08-11 |
Not clear |
| Y K Fun. The importance of nucleus accumbens in nicotine-induced locomotor activity. The Journal of pharmacy and pharmacology. vol 42. issue 8. 1991-04-15. PMID:1981594. |
this study suggests that nicotinic agonists such as nicotine and cytisine produce their locomotor excitatory effects through stimulation of the mesolimbic dopaminergic pathway. |
1991-04-15 |
2023-08-11 |
rat |
| E Museo, R A Wis. Microinjections of a nicotinic agonist into dopamine terminal fields: effects on locomotion. Pharmacology, biochemistry, and behavior. vol 37. issue 1. 1991-02-01. PMID:2263652. |
the data support the notion that systemic nicotine may interact with dopaminergic projections to the nas to produce increases in locomotor activity. |
1991-02-01 |
2023-08-11 |
rat |
| P Decina, G Caracci, R Sandik, W Berman, S Mukherjee, P Scapicchi. Cigarette smoking and neuroleptic-induced parkinsonism. Biological psychiatry. vol 28. issue 6. 1990-12-07. PMID:1977478. |
these observations are supported by neurochemical studies demonstrating enhancement of central dopaminergic neurotransmission by nicotine. |
1990-12-07 |
2023-08-11 |
Not clear |
| P B Clark. Dopaminergic mechanisms in the locomotor stimulant effects of nicotine. Biochemical pharmacology. vol 40. issue 7. 1990-11-08. PMID:2222501. |
dopaminergic mechanisms in the locomotor stimulant effects of nicotine. |
1990-11-08 |
2023-08-11 |
Not clear |
| C Prasad, S A Spah. One-year continuous low-dose nicotine intake does not alter body weight of rats. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. vol 59. issue 4. 1990-05-30. PMID:2634048. |
to investigate the potential role of nicotine in aging of dopaminergic neurons, therefore, using a dose of nicotine that has no effect on body weight becomes essential. |
1990-05-30 |
2023-08-11 |
rat |
| I P Stolerman, C Reavil. Primary cholinergic and indirect dopaminergic mediation of behavioural effects of nicotine. Progress in brain research. vol 79. 1990-01-10. PMID:2573911. |
primary cholinergic and indirect dopaminergic mediation of behavioural effects of nicotine. |
1990-01-10 |
2023-08-11 |
Not clear |
| C Owman, K Fuxe, A M Janson, J Kåhrströ. Studies of protective actions of nicotine on neuronal and vascular functions in the brain of rats: comparison between sympathetic noradrenergic and mesostriatal dopaminergic fiber systems, and the effect of a dopamine agonist. Progress in brain research. vol 79. 1990-01-10. PMID:2573912. |
studies of protective actions of nicotine on neuronal and vascular functions in the brain of rats: comparison between sympathetic noradrenergic and mesostriatal dopaminergic fiber systems, and the effect of a dopamine agonist. |
1990-01-10 |
2023-08-11 |
rat |
| C Owman, K Fuxe, A M Janson, J Kåhrströ. Studies of protective actions of nicotine on neuronal and vascular functions in the brain of rats: comparison between sympathetic noradrenergic and mesostriatal dopaminergic fiber systems, and the effect of a dopamine agonist. Progress in brain research. vol 79. 1990-01-10. PMID:2573912. |
it is concluded that nicotine, mainly through its protective action on the meso-striatal dopaminergic system, is able to improve striatal glucose utilization and associated blood flow, probably reflecting a tendency to amelioration of neurotransmission function of surviving terminals belonging to the nigro-striatal dopamine neurons. |
1990-01-10 |
2023-08-11 |
rat |