| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Garcia-Munoz, P Patino, S J Young, P M Grove. Effects of nicotine on dopaminergic nigrostriatal axons requires stimulation of presynaptic glutamatergic receptors. The Journal of pharmacology and experimental therapeutics. vol 277. issue 3. 1996-08-06. PMID:8667239. |
an electrophysiological method for evaluating changes in axonal excitability was used to examine presynaptic effects of the local striatal administration of nicotine on nigrostriatal dopaminergic terminal axons in the rat. |
1996-08-06 |
2023-08-12 |
rat |
| R Erdman. [Neuroleptics and nicotine]. Psychiatrische Praxis. vol 22. issue 6. 1996-03-07. PMID:8570751. |
nicotine, the most important content of cigarette tobacco, interacts with several receptors of neurotransmitters in the cns: especially the dopaminergic system appears to be relevant in this respect. |
1996-03-07 |
2023-08-12 |
Not clear |
| J Prigno. [Nicotine substitution as an aid in smoking cessation. Mechanisms of action, methods and evaluation of the results]. Revue des maladies respiratoires. vol 12. issue 2. 1995-06-15. PMID:7746934. |
failure in smoking cessation is linked with behavioural factors and with nicotine dependence, due to the psychoactive effects of the drug, mainly on locus ceruleus and on mesolimbic dopaminergic system. |
1995-06-15 |
2023-08-12 |
Not clear |
| J R James, A Nordber. Genetic and environmental aspects of the role of nicotinic receptors in neurodegenerative disorders: emphasis on Alzheimer's disease and Parkinson's disease. Behavior genetics. vol 25. issue 2. 1995-06-01. PMID:7733856. |
nicotine has been shown to possess some neuroprotective properties for both cholinergic and dopaminergic neurons. |
1995-06-01 |
2023-08-12 |
Not clear |
| D H Overstree. Differential effects of nicotine in inbred and selectively bred rodents. Behavior genetics. vol 25. issue 2. 1995-06-01. PMID:7733858. |
some of the differences in nicotine sensitivity may depend upon underlying differences in muscarinic sensitivity, in nicotinic receptors, and/or dopaminergic mechanisms. |
1995-06-01 |
2023-08-12 |
mouse |
| E Tirelli, J M Witki. Differential effects of direct and indirect dopamine agonists on the induction of gnawing in C57Bl/6J mice. The Journal of pharmacology and experimental therapeutics. vol 273. issue 1. 1995-05-17. PMID:7714815. |
nonetheless, the dopaminergic nature of the gnawing response was confirmed in experiments in which a host of compounds with primary actions at nondopaminergic sites did not induce gnawing; compounds included nicotine, caffeine, dizocilpine, lidocaine, fluoxetine and nisoxetine. |
1995-05-17 |
2023-08-12 |
mouse |
| T Nabeshima, A Itoh, K Kobayashi, S Morita, T Mizuguchi, H Sawada, A Nitta, T Hasegawa, K Hayashi, T Nagats. Effects of subacute administration of methamphetamine and nicotine on locomotor activity in transgenic mice expressing the human tyrosine hydroxylase gene. Journal of neural transmission. General section. vol 97. issue 1. 1995-04-17. PMID:7888148. |
to investigate differences in the dopaminergic (daergic) neuronal activity between the tg and ntg mice, we examined changes in the locomotor activity induced by methamphetamine (map) and nicotine (nic), which enhances da release and induces th enzyme activation, respectively. |
1995-04-17 |
2023-08-12 |
mouse |
| A Nitta, Y Katono, A Itoh, T Hasegawa, T Nabeshim. Nicotine reverses scopolamine-induced impairment of performance in passive avoidance task in rats through its action on the dopaminergic neuronal system. Pharmacology, biochemistry, and behavior. vol 49. issue 4. 1995-04-12. PMID:7886091. |
nicotine reverses scopolamine-induced impairment of performance in passive avoidance task in rats through its action on the dopaminergic neuronal system. |
1995-04-12 |
2023-08-12 |
rat |
| A Nitta, Y Katono, A Itoh, T Hasegawa, T Nabeshim. Nicotine reverses scopolamine-induced impairment of performance in passive avoidance task in rats through its action on the dopaminergic neuronal system. Pharmacology, biochemistry, and behavior. vol 49. issue 4. 1995-04-12. PMID:7886091. |
we investigated whether, in relation to the dopaminergic neuronal system, nicotine was effective in ameliorating the impairment of performance in passive avoidance tasks in rats induced by scopolamine, an inhibitor of muscarinic acetylcholine receptors. |
1995-04-12 |
2023-08-12 |
rat |
| A Nitta, Y Katono, A Itoh, T Hasegawa, T Nabeshim. Nicotine reverses scopolamine-induced impairment of performance in passive avoidance task in rats through its action on the dopaminergic neuronal system. Pharmacology, biochemistry, and behavior. vol 49. issue 4. 1995-04-12. PMID:7886091. |
these results suggest that nicotine, by activating the nicotinic acetylcholinergic and dopaminergic neuronal systems, ameliorates the impairment of performance in the passive avoidance task induced by a muscarinic acetylcholine receptor blocker. |
1995-04-12 |
2023-08-12 |
rat |
| J L Evenden, M Turpin, L Oliver, C Jenning. Caffeine and nicotine improve visual tracking by rats: a comparison with amphetamine, cocaine and apomorphine. Psychopharmacology. vol 110. issue 1-2. 1995-03-29. PMID:7870879. |
the present study was undertaken to determine whether these performance enhancing effects of amphetamine could also be obtained with cocaine and apomorphine, which both have psychomotor stimulant effects through their actions as, respectively, indirect and direct dopamine agonists, and by caffeine and nicotine, which do not have a direct dopaminergic mechanism of action. |
1995-03-29 |
2023-08-12 |
rat |
| M I Damaj, B R Marti. Is the dopaminergic system involved in the central effects of nicotine in mice? Psychopharmacology. vol 111. issue 1. 1995-03-29. PMID:7870924. |
is the dopaminergic system involved in the central effects of nicotine in mice? |
1995-03-29 |
2023-08-12 |
mouse |
| K Suemaru, R Oishi, Y Gomit. Characteristics of tail-tremor induced by nicotine in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 350. issue 2. 1995-01-09. PMID:7990972. |
to characterize the tail-tremor and locomotor hyperactivity induced by repeated nicotine administration, the effects of nicotinic, alpha-adrenergic and dopaminergic blockers were investigated in rats. |
1995-01-09 |
2023-08-12 |
rat |
| K Suemaru, R Oishi, Y Gomit. Characteristics of tail-tremor induced by nicotine in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 350. issue 2. 1995-01-09. PMID:7990972. |
these results suggest that nicotine-induced tail-tremor and hyperactivity are due to an increased susceptibility of central nicotinic receptors of nicotine followed by catecholaminergic mechanisms, and that tail-tremor may be more associated with the noradrenergic system than the dopaminergic system. |
1995-01-09 |
2023-08-12 |
rat |
| W A Corrigall, K M Coe. Dopamine mechanisms play at best a small role in the nicotine discriminative stimulus. Pharmacology, biochemistry, and behavior. vol 48. issue 3. 1994-11-04. PMID:7938142. |
these data suggest that dopaminergic mechanisms play, at best, a small role in the discriminative stimulus properties of nicotine. |
1994-11-04 |
2023-08-12 |
rat |
| E P Noble, S T St Jeor, T Ritchie, K Syndulko, S C St Jeor, R J Fitch, R L Brunner, R S Sparke. D2 dopamine receptor gene and cigarette smoking: a reward gene? Medical hypotheses. vol 42. issue 4. 1994-09-26. PMID:8072432. |
in as much as alcohol, cocaine, opiates, nicotine and food are known to increase brain dopamine levels and activate the mesocorticolimbic dopaminergic reward pathways of the brain, it is hypothesized that an inherited deficit of d2 dopamine receptor numbers in brain reward areas of a1 allelic subject predisposes them to substance abuse problems. |
1994-09-26 |
2023-08-12 |
human |
| K Fuxe, L Rosén, A Lippoldt, B Andbjer, U Hasselrot, U B Finnman, L F Agnat. Chronic continuous infusion of nicotine increases the disappearance of choline acetyltransferase immunoreactivity in the cholinergic cell bodies of the medial septal nucleus following a partial unilateral transection of the fimbria fornix. The Clinical investigator. vol 72. issue 4. 1994-09-01. PMID:8043972. |
in comparison with the dopaminergic neurons it may therefore be that the continuous chronic nicotine exposure does not lead to sufficient desensitization of the nicotinic cholinoceptors of the cholinergic neurons to reduce the chronic influx of sodium and calcium ions via the nicotinic ion channels and thus intraneuronal calcium levels and energy demands. |
1994-09-01 |
2023-08-12 |
rat |
| H Kiba, A Jayarama. Nicotine induced c-fos expression in the striatum is mediated mostly by dopamine D1 receptor and is dependent on NMDA stimulation. Brain research. Molecular brain research. vol 23. issue 1-2. 1994-08-08. PMID:7913201. |
the powerful psychostimulant and positive reinforcing effects of nicotine have been speculated to be mediated by the dopaminergic neurons of the ventral tegemental area (vta) and their terminals in the nucleus accumbens. |
1994-08-08 |
2023-08-12 |
rat |
| C Henry, M Le Moal, M Bourgeoi. [Individual susceptibility to addiction. Contribution of animal models]. L'Encephale. vol 20. issue 1. 1994-06-08. PMID:8174505. |
if the meso-accumbens dopaminergic pathway actually seems to underlie the reinforcing properties of psychostimulants, the question remains unsolved regarding opiates and other drugs of abuse such as benzodiazepines, nicotine or alcohol. |
1994-06-08 |
2023-08-12 |
Not clear |
| C Prasad, H Ikegami, I Shimizu, E S Onaiv. Chronic nicotine intake decelerates aging of nigrostriatal dopaminergic neurons. Life sciences. vol 54. issue 16. 1994-05-12. PMID:8152341. |
chronic nicotine intake decelerates aging of nigrostriatal dopaminergic neurons. |
1994-05-12 |
2023-08-12 |
Not clear |