| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tanuja Bordia, Neeraja Parameswaran, Hong Fan, J William Langston, J Michael McIntosh, Maryka Qui. Partial recovery of striatal nicotinic receptors in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned monkeys with chronic oral nicotine. The Journal of pharmacology and experimental therapeutics. vol 319. issue 1. 2006-11-02. PMID:16837557. |
monkeys were administered nicotine in the drinking water for 6 months and subsequently lesioned with the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) over several months while nicotine was continued. |
2006-11-02 |
2023-08-12 |
monkey |
| Mohammad-Reza Zarrindast, Negin Nouraei, Azita Khallilzadeh, Elham Askar. Influence of acute and sub-chronic nicotine pretreatment on morphine state-dependent learning. Behavioural brain research. vol 173. issue 2. 2006-11-01. PMID:16893575. |
the results suggest that nicotine may induce sensitization which affects the impairment of memory formation via cholinergic but not dopaminergic systems. |
2006-11-01 |
2023-08-12 |
mouse |
| Vincent David, Morgane Besson, Jean-Pierre Changeux, Sylvie Granon, Pierre Cazal. Reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: dependence on cholinergic nicotinic and dopaminergic D1 receptors. Neuropharmacology. vol 50. issue 8. 2006-09-28. PMID:16580026. |
reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: dependence on cholinergic nicotinic and dopaminergic d1 receptors. |
2006-09-28 |
2023-08-12 |
mouse |
| Sang Eun Kim, Insop Shim, June-Key Chung, Myung Chul Le. Effect of ginseng saponins on enhanced dopaminergic transmission and locomotor hyperactivity induced by nicotine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 8. 2006-08-31. PMID:16251992. |
effect of ginseng saponins on enhanced dopaminergic transmission and locomotor hyperactivity induced by nicotine. |
2006-08-31 |
2023-08-12 |
rat |
| Sang Eun Kim, Insop Shim, June-Key Chung, Myung Chul Le. Effect of ginseng saponins on enhanced dopaminergic transmission and locomotor hyperactivity induced by nicotine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 8. 2006-08-31. PMID:16251992. |
our data raise the possibility that gts, by attenuating nicotine-induced enhancement of dopaminergic transmission, may prove to be a useful therapeutic agent for nicotine addiction and warrant further investigation on its effect on nicotine's rewarding property. |
2006-08-31 |
2023-08-12 |
rat |
| Ji-Kyung Choi, Joseph B Mandeville, Y Iris Chen, Young R Kim, Bruce G Jenkin. High resolution spatial mapping of nicotine action using pharmacologic magnetic resonance imaging. Synapse (New York, N.Y.). vol 60. issue 2. 2006-08-10. PMID:16715493. |
this pattern of response is consistent with stimulation of both cholinergic and dopaminergic neuronal pathways and is consistent with the known behavioral properties of nicotine. |
2006-08-10 |
2023-08-12 |
rat |
| Sietse Jonkman, Athina Marko. Blockade of nicotinic acetylcholine or dopamine D1-like receptors in the central nucleus of the amygdala or the bed nucleus of the stria terminalis does not precipitate nicotine withdrawal in nicotine-dependent rats. Neuroscience letters. vol 400. issue 1-2. 2006-08-04. PMID:16563623. |
we investigated the possible involvement of nicotinic and dopaminergic signalling in the central nucleus of the amygdala (cea) and dorsolateral bed nucleus of the stria terminalis (dlbnst) in the anhedonic depression-like effect of precipitated nicotine withdrawal in rats. |
2006-08-04 |
2023-08-12 |
rat |
| Monica Mameli-Engvall, Alexis Evrard, Stéphanie Pons, Uwe Maskos, Torgny H Svensson, Jean-Pierre Changeux, Philippe Faur. Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors. Neuron. vol 50. issue 6. 2006-07-25. PMID:16772172. |
nicotine elicits dopamine release by stimulating nicotinic acetylcholine receptors (nachrs) on dopaminergic neurons. |
2006-07-25 |
2023-08-12 |
mouse |
| Monica Mameli-Engvall, Alexis Evrard, Stéphanie Pons, Uwe Maskos, Torgny H Svensson, Jean-Pierre Changeux, Philippe Faur. Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors. Neuron. vol 50. issue 6. 2006-07-25. PMID:16772172. |
we recorded, in vivo, the spontaneous activity of dopaminergic neurons in the vta of anaesthetized wt and nachr knockout mice and their response to nicotine injections. |
2006-07-25 |
2023-08-12 |
mouse |
| Nael Al Koudsi, Rachel F Tyndal. Genetic influences on smoking: a brief review. Therapeutic drug monitoring. vol 27. issue 6. 2006-05-24. PMID:16404798. |
these may include genes involved in the general aspect of dependence (eg, genes within the dopaminergic system) and those more specific to nicotine dependence (eg, genes encoding nicotinic acetylcholine receptors and nicotine-metabolizing enzymes). |
2006-05-24 |
2023-08-12 |
Not clear |
| Maryka Quik, Li Chen, Neeraja Parameswaran, Xinmin Xie, J William Langston, Sarah E McCallu. Chronic oral nicotine normalizes dopaminergic function and synaptic plasticity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned primates. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 17. 2006-05-23. PMID:16641249. |
chronic oral nicotine normalizes dopaminergic function and synaptic plasticity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned primates. |
2006-05-23 |
2023-08-12 |
monkey |
| Maryka Quik, Li Chen, Neeraja Parameswaran, Xinmin Xie, J William Langston, Sarah E McCallu. Chronic oral nicotine normalizes dopaminergic function and synaptic plasticity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned primates. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 17. 2006-05-23. PMID:16641249. |
monkeys were chronically (6 months) treated with nicotine in the drinking water and subsequently lesioned with the dopaminergic neurotoxin mptp (6 months) while nicotine was continued. |
2006-05-23 |
2023-08-12 |
monkey |
| Maryka Quik, Li Chen, Neeraja Parameswaran, Xinmin Xie, J William Langston, Sarah E McCallu. Chronic oral nicotine normalizes dopaminergic function and synaptic plasticity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned primates. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 17. 2006-05-23. PMID:16641249. |
long-term nicotine administration also attenuated the enhanced k(+)-evoked fractional dopamine release from synaptosomes of mptp-lesioned animals, suggesting that nicotine treatment had a generalized effect on dopaminergic function. |
2006-05-23 |
2023-08-12 |
monkey |
| Maryka Quik, Li Chen, Neeraja Parameswaran, Xinmin Xie, J William Langston, Sarah E McCallu. Chronic oral nicotine normalizes dopaminergic function and synaptic plasticity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned primates. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 17. 2006-05-23. PMID:16641249. |
thus, the present data show that the disruptions in striatal dopaminergic function after nigrostriatal damage were attenuated with chronic nicotine administration. |
2006-05-23 |
2023-08-12 |
monkey |
| M Mugnaini, M Garzotti, I Sartori, M Pilla, P Repeto, C A Heidbreder, M Tessar. Selective down-regulation of [(125)I]Y0-alpha-conotoxin MII binding in rat mesostriatal dopamine pathway following continuous infusion of nicotine. Neuroscience. vol 137. issue 2. 2006-05-03. PMID:16289885. |
alpha6beta2*-nicotinic acetylcholine receptors are selectively enriched in the mesostriatal dopaminergic system and may play a crucial role in nicotine dependence. |
2006-05-03 |
2023-08-12 |
rat |
| M Mugnaini, M Garzotti, I Sartori, M Pilla, P Repeto, C A Heidbreder, M Tessar. Selective down-regulation of [(125)I]Y0-alpha-conotoxin MII binding in rat mesostriatal dopamine pathway following continuous infusion of nicotine. Neuroscience. vol 137. issue 2. 2006-05-03. PMID:16289885. |
here we show that chronic nicotine treatment (3mg/kg/day for two weeks, via s.c. osmotic minipumps) caused a significant decrease (36% on average) in the binding of [(125)i]y(0)-alpha-conotoxin mii (a selective ligand for alpha6beta2*-nicotinic acetylcholine receptors in this system) to all the five regions of the rat dopaminergic pathway analyzed in this study. |
2006-05-03 |
2023-08-12 |
rat |
| M Mugnaini, M Garzotti, I Sartori, M Pilla, P Repeto, C A Heidbreder, M Tessar. Selective down-regulation of [(125)I]Y0-alpha-conotoxin MII binding in rat mesostriatal dopamine pathway following continuous infusion of nicotine. Neuroscience. vol 137. issue 2. 2006-05-03. PMID:16289885. |
in conclusion, this work is the first to demonstrate that alpha6beta2*-nicotinic acetylcholine receptors, unique within the nicotinic acetylcholine receptor family, are down-regulated following chronic nicotine treatment in rat dopaminergic mesostriatal pathway, a finding that may shed new light in the complex mechanisms of nicotine dependence. |
2006-05-03 |
2023-08-12 |
rat |
| Sanna Janhunen, Paula Mielikäinen, Päivi Paldánius, Raimo K Tuominen, Liisa Ahtee, Seppo Kaakkol. The effect of nicotine in combination with various dopaminergic drugs on nigrostriatal dopamine in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 371. issue 6. 2006-04-28. PMID:16012872. |
the effect of nicotine in combination with various dopaminergic drugs on nigrostriatal dopamine in rats. |
2006-04-28 |
2023-08-12 |
rat |
| Sanna Janhunen, Paula Mielikäinen, Päivi Paldánius, Raimo K Tuominen, Liisa Ahtee, Seppo Kaakkol. The effect of nicotine in combination with various dopaminergic drugs on nigrostriatal dopamine in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 371. issue 6. 2006-04-28. PMID:16012872. |
it is well established that nicotine activates brain dopaminergic systems and in addition has neuroprotective actions. |
2006-04-28 |
2023-08-12 |
rat |
| Sanna Janhunen, Paula Mielikäinen, Päivi Paldánius, Raimo K Tuominen, Liisa Ahtee, Seppo Kaakkol. The effect of nicotine in combination with various dopaminergic drugs on nigrostriatal dopamine in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 371. issue 6. 2006-04-28. PMID:16012872. |
thus, nicotinic acetylcholine receptor (nachr) agonists might be beneficial in the treatment of parkinson's disease, and it is important to study the interactions of nicotine with drugs affecting the nigrostriatal dopaminergic pathway. |
2006-04-28 |
2023-08-12 |
rat |