| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J L Wilkinson, F I Carroll, R A Bevin. An investigation of bupropion substitution for the interoceptive stimulus effects of nicotine. Journal of psychopharmacology (Oxford, England). vol 24. issue 6. 2010-08-20. PMID:19304864. |
additionally, it has been hypothesised that bupropion and nicotine have an overlapping dopaminergic mechanism. |
2010-08-20 |
2023-08-12 |
rat |
| Marcelo O Ortells, Georgina E Barrante. Tobacco addiction: a biochemical model of nicotine dependence. Medical hypotheses. vol 74. issue 5. 2010-08-18. PMID:19962246. |
the main effects of nicotine associated with smoking are nachr upregulation, nachr desensitization and modulation of the dopaminergic system. |
2010-08-18 |
2023-08-12 |
Not clear |
| Mohammad-Reza Zarrindast, Nima Naghdi-Sedeh, Mohammad Nasehi, Hedayat Sahraei, Farideh Bahrami, Fereshteh Asad. The effects of dopaminergic drugs in the ventral hippocampus of rats in the nicotine-induced anxiogenic-like response. Neuroscience letters. vol 475. issue 3. 2010-06-30. PMID:20363294. |
nicotine an active alkaloid of tobacco has dopaminergic properties. |
2010-06-30 |
2023-08-12 |
rat |
| Mohammad-Reza Zarrindast, Nima Naghdi-Sedeh, Mohammad Nasehi, Hedayat Sahraei, Farideh Bahrami, Fereshteh Asad. The effects of dopaminergic drugs in the ventral hippocampus of rats in the nicotine-induced anxiogenic-like response. Neuroscience letters. vol 475. issue 3. 2010-06-30. PMID:20363294. |
the possible involvement of ventral hippocampal dopaminergic receptor mechanism in the nicotine influence on anxiogenic-like response has been investigated in the present study. |
2010-06-30 |
2023-08-12 |
rat |
| Xiu Liu, Courtney Jernigen, Maysa Gharib, Sheri Booth, Anthony R Caggiula, Alan F Sve. Effects of dopamine antagonists on drug cue-induced reinstatement of nicotine-seeking behavior in rats. Behavioural pharmacology. vol 21. issue 2. 2010-06-17. PMID:20168211. |
these findings suggest that manipulation of dopaminergic neurotransmission at d1 and/or d2 receptors may prove to be a potential target for the development of pharmacotherapy for prevention of environmental nicotine cue-triggered smoking relapse. |
2010-06-17 |
2023-08-12 |
rat |
| Darcy Shaw, Mustafa al'Abs. Blunted opiate modulation of prolactin response in smoking men and women. Pharmacology, biochemistry, and behavior. vol 95. issue 1. 2010-06-01. PMID:19969014. |
this study was developed to examine how nicotine dependence alters endogenous opioid regulation of prolactin response, a peripheral marker of dopaminergic activity. |
2010-06-01 |
2023-08-12 |
Not clear |
| Lei Phillip Wang, Fei Li, Xiaoming Shen, Joe Z Tsie. Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. PloS one. vol 5. issue 1. 2010-05-20. PMID:20062537. |
it is known that nicotine triggers tobacco addiction by activating nicotine acetylcholine receptors (nachrs) in the midbrain dopaminergic reward system, primarily via the ventral tegmental area. |
2010-05-20 |
2023-08-12 |
mouse |
| Kavita Singh, Seema Singh, Naveen Kumar Singhal, Amit Sharma, Devendra Parmar, Mahendra Pratap Sing. Nicotine- and caffeine-mediated changes in gene expression patterns of MPTP-lesioned mouse striatum: Implications in neuroprotection mechanism. Chemico-biological interactions. vol 185. issue 2. 2010-05-10. PMID:20230807. |
exposure to 1-methyl 4-phenyl 1,2,3,6-tetrahydropyridine (mptp) induces dopaminergic neurodegeneration in the nigrostriatal pathway and nicotine and caffeine ameliorate neurodegenerative changes in mptp-lesioned mouse model of parkinson's disease (pd). |
2010-05-10 |
2023-08-12 |
mouse |
| Theresa A Zesiewicz, Marian L Evat. Potential influences of complementary therapy on motor and non-motor complications in Parkinson's disease. CNS drugs. vol 23. issue 10. 2010-05-04. PMID:19739693. |
complementary therapies, such as altered diet, dietary supplements, vitamin therapy, herbal supplements, caffeine, nicotine, exercise, physical therapy, massage therapy, melatonin, bright-light therapy and acupuncture, may all influence the symptoms of pd and/or the effectiveness of dopaminergic therapy. |
2010-05-04 |
2023-08-12 |
Not clear |
| Taryn E Grieder, Laurie H Sellings, Hector Vargas-Perez, Ryan Ting-A-Kee, Eric C Siu, Rachel F Tyndale, Derek van der Koo. Dopaminergic signaling mediates the motivational response underlying the opponent process to chronic but not acute nicotine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 4. 2010-04-28. PMID:20032966. |
dopaminergic signaling mediates the motivational response underlying the opponent process to chronic but not acute nicotine. |
2010-04-28 |
2023-08-12 |
mouse |
| Taryn E Grieder, Laurie H Sellings, Hector Vargas-Perez, Ryan Ting-A-Kee, Eric C Siu, Rachel F Tyndale, Derek van der Koo. Dopaminergic signaling mediates the motivational response underlying the opponent process to chronic but not acute nicotine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 4. 2010-04-28. PMID:20032966. |
it has been suggested that the dopaminergic system is also involved in the aversive motivational response to drug withdrawal, particularly for opiates, however, the role for dopaminergic signaling in the processing of the negative motivational properties of nicotine withdrawal is largely unknown. |
2010-04-28 |
2023-08-12 |
mouse |
| Taryn E Grieder, Laurie H Sellings, Hector Vargas-Perez, Ryan Ting-A-Kee, Eric C Siu, Rachel F Tyndale, Derek van der Koo. Dopaminergic signaling mediates the motivational response underlying the opponent process to chronic but not acute nicotine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 4. 2010-04-28. PMID:20032966. |
we hypothesized that signaling at dopaminergic receptors mediates chronic nicotine withdrawal aversions and that dopaminergic signaling would differentially mediate acute vs dependent nicotine motivation. |
2010-04-28 |
2023-08-12 |
mouse |
| Taryn E Grieder, Laurie H Sellings, Hector Vargas-Perez, Ryan Ting-A-Kee, Eric C Siu, Rachel F Tyndale, Derek van der Koo. Dopaminergic signaling mediates the motivational response underlying the opponent process to chronic but not acute nicotine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 4. 2010-04-28. PMID:20032966. |
taken together, these results suggest that dopaminergic signaling is necessary for the opponent motivational response to nicotine in dependent, but not non-dependent, rodents. |
2010-04-28 |
2023-08-12 |
mouse |
| Maryka Quik, Carla Campos, Neeraja Parameswaran, J William Langston, J Michael McIntosh, Michael Yeluashvil. Chronic nicotine treatment increases nAChRs and microglial expression in monkey substantia nigra after nigrostriatal damage. Journal of molecular neuroscience : MN. vol 40. issue 1-2. 2010-04-21. PMID:19685015. |
our previous work had shown that long-term nicotine administration improved dopaminergic markers and nicotinic receptors (nachrs) in the striatum of monkeys with nigrostriatal damage. |
2010-04-21 |
2023-08-12 |
monkey |
| Maryka Quik, Carla Campos, Neeraja Parameswaran, J William Langston, J Michael McIntosh, Michael Yeluashvil. Chronic nicotine treatment increases nAChRs and microglial expression in monkey substantia nigra after nigrostriatal damage. Journal of molecular neuroscience : MN. vol 40. issue 1-2. 2010-04-21. PMID:19685015. |
the present experiments were done to determine whether nicotine treatment also led to changes in the substantia nigra, the region containing dopaminergic cell bodies. |
2010-04-21 |
2023-08-12 |
monkey |
| K Ohyama, C Sogawa, N Sogawa, K Morita, T Dohi, S Kitayam. Nicotine stimulates transcriptional activity of the human dopamine transporter gene. Neuroscience letters. vol 471. issue 1. 2010-04-05. PMID:20074615. |
nicotine modulates dopaminergic activity in the central nervous system by acting on the reuptake system, including the dopamine transporter (dat), although precisely remains unclear. |
2010-04-05 |
2023-08-12 |
human |
| Anne-Marie Duchemin, Hailing Zhang, Norton H Neff, Maria Hadjiconstantino. Increased expression of VMAT2 in dopaminergic neurons during nicotine withdrawal. Neuroscience letters. vol 467. issue 2. 2010-02-01. PMID:19835933. |
increased expression of vmat2 in dopaminergic neurons during nicotine withdrawal. |
2010-02-01 |
2023-08-12 |
mouse |
| Anne-Marie Duchemin, Hailing Zhang, Norton H Neff, Maria Hadjiconstantino. Increased expression of VMAT2 in dopaminergic neurons during nicotine withdrawal. Neuroscience letters. vol 467. issue 2. 2010-02-01. PMID:19835933. |
da is an important mediator of the behavioral actions of nicotine, and dopaminergic neurotransmission is altered following nicotine administration. |
2010-02-01 |
2023-08-12 |
mouse |
| Anne-Marie Duchemin, Hailing Zhang, Norton H Neff, Maria Hadjiconstantino. Increased expression of VMAT2 in dopaminergic neurons during nicotine withdrawal. Neuroscience letters. vol 467. issue 2. 2010-02-01. PMID:19835933. |
vmat2 up-regulation might be a compensatory mechanism to restore and maintain synaptic transmission in dopaminergic midbrain neurons during nicotine withdrawal. |
2010-02-01 |
2023-08-12 |
mouse |
| Kazuhiko Iwahashi, Jun Aok. A review of smoking behavior and smokers evidence (chemical modification, inducing nicotine metabolism, and individual variations by genotype: dopaminergic function and personality traits). Drug and chemical toxicology. vol 32. issue 4. 2010-01-15. PMID:19793020. |
a review of smoking behavior and smokers evidence (chemical modification, inducing nicotine metabolism, and individual variations by genotype: dopaminergic function and personality traits). |
2010-01-15 |
2023-08-12 |
human |