| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H A Sahyoun, B Costall, R J Naylo. On the ability of domperidone to selectively inhibit catecholamine-induced relaxation of circular smooth muscle of guinea-pig stomach. The Journal of pharmacy and pharmacology. vol 34. issue 1. 1982-05-12. PMID:6121028. |
domperidone and haloperidol were found to selectively inhibit the phenylephrine- noradrenaline- and dopamine-induced relaxations of the stomach strips and to enhance the contractile component of dopamine's action: this ability of domperidone to facilitate a dopamine induced contraction, which was most marked in the body and antral regions, was prevented by phentolamine. |
1982-05-12 |
2023-08-12 |
Not clear |
| R Shukla, R C Srimal, B N Dhawa. The effect of intracerebroventricular administration of catecholamines and their antagonists on rectal temperature of Mastomys natalensis. Naunyn-Schmiedeberg's archives of pharmacology. vol 318. issue 1. 1982-04-20. PMID:6120469. |
dopamine (0.5-20 microgram) and its agonists apomorphine, amantadine and bs 9641 produced hyperthermia which was antagonised by haloperidol and pimozide but not by alpha- or beta adrenoceptor antagonists. |
1982-04-20 |
2023-08-12 |
Not clear |
| L K Rägo, L H Allikmets, A M Zarkovsk. Effects of piracetam on the central dopaminergic transmission. Naunyn-Schmiedeberg's archives of pharmacology. vol 318. issue 1. 1982-04-20. PMID:6276786. |
the effects of piracetam on dopamine metabolism in rat striatal tissue and on behavioural and biochemical effects of haloperidol were studied. |
1982-04-20 |
2023-08-12 |
rat |
| A M Zharkovskiĭ, L Kh Allikmets, A M Nur. [Influence of the intracaudate administration of kainic acid on the effects of the prolonged use of haloperidol and apomorphine on rats]. Farmakologiia i toksikologiia. vol 45. issue 1. 1982-04-20. PMID:7198997. |
in rats injected with kainic acid into the dorsal part of the caudate nucleus, the chronic treatment (for 20 days) with haloperidol (1 mg/kg) did not induce hypersensitivity of dopamine receptors. |
1982-04-20 |
2023-08-12 |
rat |
| A E Snow, S M Tucker, W L Dewe. The role of neurotransmitters in stress-induced antinociception (SIA). Pharmacology, biochemistry, and behavior. vol 16. issue 1. 1982-04-12. PMID:6120525. |
when dopaminergic tone was increased with apomorphine (0.05 mg/kg, sc) the increase of tail-flick latency after stress was markedly attenuated whereas blockage of dopamine receptors with haloperidol (2.5 mg/kg, ip) increased the peak and duration of sia. |
1982-04-12 |
2023-08-12 |
Not clear |
| J M Farah, D S Malcolm, G P Muelle. Dopaminergic inhibition of pituitary beta-endorphin-like immunoreactivity secretion in the rat. Endocrinology. vol 110. issue 2. 1982-04-12. PMID:6276143. |
blockade of dopamine receptors by haloperidol or pimozide treatment evoked dose- and time-related increases in plasma levels of beta-end-li. |
1982-04-12 |
2023-08-12 |
rat |
| A M Zharkovskiĭ, A M Nur. [Effect of intracaudate administration of kainic acid on the activity of the dopaminergic system]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 67. issue 11. 1982-04-12. PMID:6799331. |
the administration of apomorphine and haloperidol in kainic-treated rats showed that apomorphine exerted its effect on the dopamine metabolism presumably via the presynaptic receptors while haloperidol acted on both pre- and postsynaptic receptors. |
1982-04-12 |
2023-08-12 |
rat |
| G Stock, P Kumme. Long-term application of haloperidol: effects on dopamine and acetylcholine receptors. International pharmacopsychiatry. vol 16. issue 3. 1982-03-22. PMID:6797983. |
long-term application of haloperidol: effects on dopamine and acetylcholine receptors. |
1982-03-22 |
2023-08-12 |
rat |
| S Lipsk. Influence of phentolamine and other drugs on proliferation of hemopoietic stem cells and on postirradiation survival of Swiss mice. Polish journal of pharmacology and pharmacy. vol 33. issue 3. 1982-03-22. PMID:7033942. |
the effect of combination of drugs composed of phentolamine (phe), 5-hydroxytryptophan (5-htp), dopamine (da), and haloperidol (hal), which is known to inhibit differentiation of lymphocytes [15, 16, 17] on the hemopoietic stem cells forming colonies in the spleen (cfu-s) of mice was investigated. |
1982-03-22 |
2023-08-12 |
mouse |
| F Nicoletti, F Patti, D F Condorelli, L Rampello, G Giammona, R M Di Giorgio, P L Canonico, U Scapagnin. Comparative effects of chronic haloperidol and sulpiride treatment on nigral and striatal GABA content. Journal of neurochemistry. vol 37. issue 4. 1982-03-22. PMID:7320718. |
however, low doses (30 micrograms/kg, intraperitoneally) of the dopamine-receptor agonist apomorphine, injected 12 h after the discontinuation of chronic haloperidol or chronic sulpiride treatment, induced opposite changes in nigral gaba levels suggesting the existence of a different "status" of the dopamine receptors during the 12 h-period following the withdrawal of haloperidol or sulpiride. |
1982-03-22 |
2023-08-12 |
rat |
| D D Thiessen, M Upchurc. Haloperidol and clonidine increase, and apomorphine decreases ultrasonic vocalizations by gerbils. Psychopharmacology. vol 75. issue 3. 1982-03-13. PMID:6119731. |
haloperidol (1 mg/kg ip), a dopamine antagonist, and clonidine (0.1 mg/kg ip), a norepinephrine agonist, increased ultrasonic signaling, and apomorphine (5 mg/kg ip), a dopamine agonist, decreased ultrasonic signaling. |
1982-03-13 |
2023-08-12 |
Not clear |
| T Di Paolo, P Poyet, F Labri. Effect of chronic estradiol and haloperidol treatment on striatal dopamine receptors. European journal of pharmacology. vol 73. issue 1. 1982-03-13. PMID:7198580. |
effect of chronic estradiol and haloperidol treatment on striatal dopamine receptors. |
1982-03-13 |
2023-08-12 |
Not clear |
| M Globus, B Lerer, R Hamburger, R H Belmake. Chronic electroconvulsive shock and chronic haloperidol administration are not additive in effects on dopamine receptors. Neuropharmacology. vol 20. issue 11. 1982-03-13. PMID:7198723. |
chronic electroconvulsive shock and chronic haloperidol administration are not additive in effects on dopamine receptors. |
1982-03-13 |
2023-08-12 |
Not clear |
| T Verimer, J P Long, J R Flynn, S P Arnerić, B J Wals. Subsensitivity of the presynaptic dopamine receptors in cat heart after the termination of chronic haloperidol treatment. Archives internationales de pharmacodynamie et de therapie. vol 253. issue 2. 1982-03-13. PMID:7198898. |
subsensitivity of the presynaptic dopamine receptors in cat heart after the termination of chronic haloperidol treatment. |
1982-03-13 |
2023-08-12 |
cat |
| T Verimer, J P Long, J R Flynn, S P Arnerić, B J Wals. Subsensitivity of the presynaptic dopamine receptors in cat heart after the termination of chronic haloperidol treatment. Archives internationales de pharmacodynamie et de therapie. vol 253. issue 2. 1982-03-13. PMID:7198898. |
these results suggest that presynaptic dopamine receptors on cat cardioaccelerator nerve terminals become subsensitive following withdrawal of chronic haloperidol treatment. |
1982-03-13 |
2023-08-12 |
cat |
| S Arbilla, L A Kamal, S Z Lange. Inhibition by apomorphine of the potassium-evoked release of [3H]-gamma-aminobutyric acid from the rat substantia nigra in vitro. British journal of pharmacology. vol 74. issue 2. 1982-03-13. PMID:7317688. |
in vivo administration of haloperidol 0.2 mg/kg antagonized the in vitro inhibition by apomorphine of the k(+)-evoked release of [(3)h]-gaba.5 the results obtained with apomorphine and haloperidol suggest the presence of presynaptic dopamine-like inhibitory receptors in gabaergic nerve terminals.6 dopamine in concentrations ranging up to 300 mum did not modify either the spontaneous or the k(+)-evoked release of [(3)h]-gaba from the substantia nigra. |
1982-03-13 |
2023-08-12 |
rat |
| L D'Angelo, J M Mont. Effects of oxolinic acid on the sleep-wakefulness cycle of the rat. British journal of pharmacology. vol 74. issue 2. 1982-03-13. PMID:7317689. |
1 a study was carried out in rats (prepared for chronic sleep recording) of the effects of oxolinic acid on the sleep-wakefulness cycle.2 in addition, the actions of oxolinic acid on the sleep-wake cycle were assessed after pretreatment with drugs interfering with central catecholamine mechanisms or facilitating central gamma-aminobutyric acid (gaba) activity.3 oxolinic acid (8-32 mg/kg) induced a significant and dose-related increase of waking eeg, while slow wave and rem sleep were decreased.4 the effects of oxolinic acid on waking, slow wave and rem sleep were antagonized by alpha-methyl-p-tyrosine (50-100 mg/kg) which interferes with the synthesis of catecholamines.5 fla-63 (25 mg/kg) which is a specific inhibitor of noradrenaline synthesis, was effective in blocking oxolinic acid-related increase of waking and decrease of slow wave sleep.6 haloperidol (0.4-0.6 mg/kg) which blocks central dopamine and noradrenaline receptors, reversed oxolinic acid-induced actions on waking and slow wave sleep. |
1982-03-13 |
2023-08-12 |
rat |
| G Almazan, T L Sourke. Effect of haloperidol on adrenal ornithine decarboxylase activity of the rat. European journal of pharmacology. vol 75. issue 2-3. 1982-03-13. PMID:7318901. |
the administration of the dopamine antagonist haloperidol (hlp) to rats produced a temporary increase in adrenomedullary and cortical ornithine decarboxylase (odc) activity. |
1982-03-13 |
2023-08-12 |
rat |
| Y Watanabe, T Matsumiya, T Ok. Effects of fusaric (5-butylpicolinic) acid on the monosynaptic reflex neural activity of cat spinal cord. The Tokai journal of experimental and clinical medicine. vol 6. issue 4. 1982-03-13. PMID:7324082. |
the fa-induced neural activity was gradually depressed by treatment with haloperidol, a dopamine and/or a alpha receptor blocker and methysergide, a serotonin receptor blocker, respectively. |
1982-03-13 |
2023-08-12 |
cat |
| I Takayanagi, H Murakami, Y Iwayama, Y Yoshida, S Mik. Dopamine receptor in anterior byssus retractor muscle of Mytilus edulis. Japanese journal of pharmacology. vol 31. issue 2. 1982-02-25. PMID:7311143. |
the concentration-curves of dopamine, its derivatives and norepinephrine shifted in parallel with application of haloperidol but were not influenced by the alpha- and beta-adrenoceptor antagonists. |
1982-02-25 |
2023-08-12 |
Not clear |