| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Pazos, A Mediavilla, J Flóre. Cardiovascular effects of intracerebroventricular injection of dopamine after selective MAO inhibition in rats. Neuropharmacology. vol 21. issue 4. 1982-08-07. PMID:6283412. |
the persistent hypotensive action of dopamine in clorgyline-pretreated rats was abolished by the central blockade of alpha-adrenoreceptors with intracerebroventricular injection of phentolamine, whereas haloperidol given by the same route did not affect the hypotensive response. |
1982-08-07 |
2023-08-12 |
rat |
| J E Leysen, P Van Gompe. Effects of proteolytic enzymes and monovalent ions demonstrate protease-sensitive and protease-insensitive stereospecific binding sites on dopaminergic receptors in rat striatum. Biochemical pharmacology. vol 31. issue 7. 1982-08-07. PMID:7046754. |
rat striatal membranes from different subcellular fractions were treated with various proteolytic and other enzymes and the binding of a dopamine agonist ([3h]npa) and of an antagonist ([3h]haloperidol) was assayed in several conditions. |
1982-08-07 |
2023-08-12 |
rat |
| D A Bergstrom, S D Bromley, J R Walter. Apomorphine increases the activity of rat globus pallidus neurons. Brain research. vol 238. issue 1. 1982-08-07. PMID:7083021. |
blockade of dopamine receptors by administration of haloperidol did cause a moderate reduction in neuronal activity but only after administration of fairly high doses. |
1982-08-07 |
2023-08-12 |
rat |
| M H Jalilian-Tehrani, G Karakiulakis, C B Le Blond, R Powell, P J Thoma. Androgen-induced sexual dimorphism in high affinity dopamine binding in the brain transcends the hypothalamic-limbic region. British journal of pharmacology. vol 75. issue 1. 1982-07-22. PMID:7074286. |
the relative inhibitory effects of haloperidol, apomorphine, cis-flupenthixol, unlabelled dopamine, noradrenaline, spiroperone, (+)-butaclamol, fluphenazine, pimozide and 5-ht on [3h]-dopamine binding in the cerebral cortex was consistent with receptor status for the binding components there as were the relative inhibitory effects of methysergide, dopamine, fluoxetine and ouabain on [3h]-5-ht binding in the fore brain. |
1982-07-22 |
2023-08-12 |
rat |
| A S Levine, J E Morley, G Wilcox, D M Brown, B S Handwerge. Tail pinch behavior and analgesia in diabetic mice. Physiology & behavior. vol 28. issue 1. 1982-07-22. PMID:7079321. |
all tail pinch behaviors were obliterated by the dopamine antagonist haloperidol; and the opiate antagonist, naltrexone, decreased eating without altering chewing. |
1982-07-22 |
2023-08-12 |
mouse |
| F J White, J B Appe. Training dose as a factor in LSD-saline discrimination. Psychopharmacology. vol 76. issue 1. 1982-07-19. PMID:6805003. |
in contrast to 5-ht, dopamine (da) did not appear to be involved in the discriminative stimulus properties of lsd, because no significant dose or group effects were seen during tests with the da agonists apomorphine and d-amphetamine or the da antagonist haloperidol. |
1982-07-19 |
2023-08-12 |
rat |
| A A Larson, M H Kondzielsk. Serotonin-induced gnawing in rats: comparison with tail pinch-induced gnawing. Pharmacology, biochemistry, and behavior. vol 16. issue 3. 1982-07-19. PMID:6896237. |
failure of intrathecally injected haloperidol to inhibit serotonin-induced gnawing indicates that dopamine mediates this behavior at a supraspinal level. |
1982-07-19 |
2023-08-12 |
rat |
| M B Bowers, A Roziti. Dopamine metabolites and catalepsy after lithium and haloperidol. European journal of pharmacology. vol 78. issue 1. 1982-07-19. PMID:7200429. |
dopamine metabolites and catalepsy after lithium and haloperidol. |
1982-07-19 |
2023-08-12 |
rat |
| D F Condorelli, G Giammona, F Patti, F Nicoletti, L Rampello, A Reggio, M Matera, R M Di Giorgi. Effects of different doses of apomorphine on GAD activity in rat substantia nigra. Italian journal of neurological sciences. vol 2. issue 3. 1982-07-19. PMID:7341553. |
the effects of different doses of the dopamine (da) receptor agonist apomorphine on the activity of the gamma-aminobutyric acid (gaba)-synthesizing enzyme glutamic acid decarboxylase (gad, ec 4.1.1.15) were investigated in rat substantia nigra in comparison with haloperidol and sulpiride, two da receptor blocking agents. |
1982-07-19 |
2023-08-12 |
rat |
| T F Seeger, L Thal, E L Gardne. Behavioral and biochemical aspects of neuroleptic-induced dopaminergic supersensitivity: studies with chronic clozapine and haloperidol. Psychopharmacology. vol 76. issue 2. 1982-07-08. PMID:6805029. |
rats were chronically injected with saline, clozapine, or haloperidol and tested for alterations in dopamine (da)-mediated behavior, da receptor binding, and both acetylcholine (ach) concentration and choline acetylase activity. |
1982-07-08 |
2023-08-12 |
rat |
| M Donowitz, S Cusolito, L Battisti, R Fogel, G W Shar. Dopamine stimulation of active Na and Cl absorption in rabbit ileum: interaction with alpha 2-adrenergic and specific dopamine receptors. The Journal of clinical investigation. vol 69. issue 4. 1982-07-08. PMID:7076842. |
the effect of dopamine on short-circuit current was inhibited by the dopamine antagonists haloperidol and domperidone and the alpha(2)-adrenergic antagonist yohimbine; there was no effect of the alpha(1)-antagonist prazosin and the beta-antagonist propranolol. |
1982-07-08 |
2023-08-12 |
rabbit |
| P Jenner, M D Hall, K Murugaiah, N Rupniak, A Theodorou, C D Marsde. Repeated administration of sulpiride for three weeks produces behavioural and biochemical evidence for cerebral dopamine receptor supersensitivity. Biochemical pharmacology. vol 31. issue 3. 1982-06-21. PMID:7200363. |
striatal dopamine sensitive adenylate cyclase activity was unaltered by such a pretreatment with either haloperidol or sulpiride. |
1982-06-21 |
2023-08-12 |
rat |
| P Jenner, M D Hall, K Murugaiah, N Rupniak, A Theodorou, C D Marsde. Repeated administration of sulpiride for three weeks produces behavioural and biochemical evidence for cerebral dopamine receptor supersensitivity. Biochemical pharmacology. vol 31. issue 3. 1982-06-21. PMID:7200363. |
the data show that sulpiride, like haloperidol, is capable of inducing behavioural and biochemical supersensitivity of cerebral dopamine receptors. |
1982-06-21 |
2023-08-12 |
rat |
| F Bergman. Stereotyped responses of rats to two 2-halogenoergolines: 2-bromo-alpha-ergocryptine and lergotrile. Israel journal of medical sciences. vol 18. issue 1. 1982-06-14. PMID:6121772. |
haloperidol, a dopamine antagonist, blocked the lergotrile-induced stereotypy within a few minutes, but had a rather slow effect on the response to bec. |
1982-06-14 |
2023-08-12 |
rat |
| A H Tissar. Increase of dopamine synthesis in synaptosomes from rats treated with neuroleptics or reserpine. Medical biology. vol 60. issue 1. 1982-06-14. PMID:6121960. |
dopamine (da) synthesis in rat striatum was increased three- to four-fold by in vivo treatment with gammabutyrolactone (gbl), reserpine, haloperidol and (-)sulpiride. |
1982-06-14 |
2023-08-12 |
rat |
| R B Rastogi, R L Singhal, Y D Lapierr. Comparative effects of short- and long-term treatment with neuroleptics on behavioural activity as well as dopamine turnover in striatum. General pharmacology. vol 13. issue 1. 1982-05-27. PMID:6120880. |
the endogenous concentration of dopamine remained unchanged in striatum and other brain regions examined, except in hippocampus where it was slightly (20%), but significantly decreased by acute haloperidol treatment. |
1982-05-27 |
2023-08-12 |
rat |
| R B Rastogi, R L Singhal, Y D Lapierr. Comparative effects of short- and long-term treatment with neuroleptics on behavioural activity as well as dopamine turnover in striatum. General pharmacology. vol 13. issue 1. 1982-05-27. PMID:6120880. |
our data demonstrate that tolerance develops to the stimulating effect of haloperidol and chlorpromazine on striatal dopamine turnover. |
1982-05-27 |
2023-08-12 |
rat |
| N G Bacopoulos, G Bustos, D E Redmond, R H Rot. Chronic treatment with haloperidol or fluphenazine decanoate: regional effects on dopamine and serotonin metabolism in primate brain. The Journal of pharmacology and experimental therapeutics. vol 221. issue 1. 1982-05-27. PMID:6174729. |
chronic treatment with haloperidol or fluphenazine decanoate: regional effects on dopamine and serotonin metabolism in primate brain. |
1982-05-27 |
2023-08-12 |
Not clear |
| H A Zacur, W E Mitch, J E Tyson, P T Ostrow, G V Foste. Autoregulation of rat pituitary prolactin secretion demonstrated by a new perfusion method. The American journal of physiology. vol 242. issue 4. 1982-05-27. PMID:7065237. |
thyrotropin-releasing hormone (10 ng/ml) did not stimulate prolactin release; dopamine (20 ng/ml) rapidly, but transiently inhibited prolactin release; bromocriptine (20 ng/ml) rapidly and persistently inhibited prolactin release; haloperidol (100 ng/ml) blocked the inhibition by dopamine or bromocriptine, but when given alone inhibited prolactin release. |
1982-05-27 |
2023-08-12 |
rat |
| R Van Buskirk, J E Dowlin. Isolated horizontal cells from carp retina demonstrate dopamine-dependent accumulation of cyclic AMP. Proceedings of the National Academy of Sciences of the United States of America. vol 78. issue 12. 1982-05-21. PMID:6278491. |
the dopamine-dependent accumulation of cyclic amp in intact isolated horizontal cells was blocked by nanomolar concentrations of dopamine antagonists such as haloperidol, (+)-butaclamol, and fluphenazine. |
1982-05-21 |
2023-08-12 |
Not clear |