| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Kazun. Dopamine-induced cyclic AMP increase in canine myocardium, kidney and superior mesenteric artery. Acta medica Okayama. vol 36. issue 2. 1982-12-16. PMID:6182759. |
haloperidol slightly inhibited the effect of dopamine and completely blocked the effect of apomorphine in the myocardium and kidney. |
1982-12-16 |
2023-08-12 |
Not clear |
| M T Lin, B L Tsay, F F Che. Activation of dopaminergic receptors within the caudate-putamen complex facilitates reflex bradycardia in the rat. The Japanese journal of physiology. vol 32. issue 3. 1982-12-16. PMID:7131940. |
furthermore, local injection of a dopamine receptor agonist apomorphine into the caudate-putamen complex (cp) facilitated reflex bradycardia, while intra-cp injection of dopamine antagonists such as haloperidol and pimozide inhibited it. |
1982-12-16 |
2023-08-12 |
rat |
| R Neale, S Gerhardt, S Fallon, J M Liebma. Progressive changes in the acute dyskinetic syndrome as a function of repeated elicitation in squirrel monkeys. Psychopharmacology. vol 77. issue 3. 1982-12-03. PMID:6126906. |
the relative incidence of these motor disorders was examined as the syndrome was repeatedly elicited by haloperidol and other dopamine antagonists in individual monkeys. |
1982-12-03 |
2023-08-12 |
monkey |
| M Itoh, B L Furman, J E Geric. Dopaminergic suppression of pancreatic somatostatin secretion. Acta endocrinologica. vol 101. issue 1. 1982-12-03. PMID:6126981. |
maximum suppression of irs and iri release was evident at 20 micro m dopamine with half-maximal suppression occurring at 0.5-1 micro m. maximal stimulation of irg release was observed at 100 micro m dopamine with a half-maximal response occurring at 5-10 micro m. suppression of irs secretion by dopamine (20 micro m) was completely reversed by the dopaminergic antagonists haloperidol (5 micro m) and pimozide (5 micro m) but was only partially reversed by the alpha adrenergic antagonist phentolamine (2 micro m), and was further suppressed by the beta adrenergic antagonist phentolamine (2 micro m). |
1982-12-03 |
2023-08-12 |
rat |
| M Itoh, B L Furman, J E Geric. Dopaminergic suppression of pancreatic somatostatin secretion. Acta endocrinologica. vol 101. issue 1. 1982-12-03. PMID:6126981. |
suppression of iri release by dopamine was completely reversed by propranolol, but was unaffected by haloperidol, pimozide, and phentolamine. |
1982-12-03 |
2023-08-12 |
rat |
| J S Carp, R J Anderso. Dopamine receptor-mediated depression of spinal monosynaptic transmission. Brain research. vol 242. issue 2. 1982-12-02. PMID:6126249. |
this effect was prevented by pretreatment with the dopamine antagonists haloperidol and metoclopramide, but not with the alpha-adrenergic antagonist phentolamine. |
1982-12-02 |
2023-08-12 |
cat |
| L M Gunne, J Growdon, B Glaese. Oral dyskinesia in rats following brain lesions and neuroleptic drug administration. Psychopharmacology. vol 77. issue 2. 1982-12-02. PMID:6126902. |
dopamine agonists (apomorphine) and antagonists (haloperidol) both lowered chewing behavior analogous to reported effects on td and so did gabaculine. |
1982-12-02 |
2023-08-12 |
human |
| N Vaysse, J Laval, C Senarens, J P Esteve, A Ribe. Dopamine-stimulated cyclic AMP and binding of [3H] dopamine in acini from dog pancreas. Biochimica et biophysica acta. vol 720. issue 4. 1982-12-02. PMID:6180776. |
cyclic amp accumulation caused by dopamine was detected at 1.10(-8) m and was half-maximal at 7.9 +/- 3.4 10(-7) m. the increase at 1.10(-5) m, (7.5-fold) was equal to the half-maximal increase caused by secretin at 1.10(-9) m. haloperidol, a dopaminergic receptor antagonist inhibited cyclic amp accumulation caused by dopamine. |
1982-12-02 |
2023-08-12 |
dog |
| N Vaysse, J Laval, C Senarens, J P Esteve, A Ribe. Dopamine-stimulated cyclic AMP and binding of [3H] dopamine in acini from dog pancreas. Biochimica et biophysica acta. vol 720. issue 4. 1982-12-02. PMID:6180776. |
the ic50 value for haloperidol, calculated from the inhibition of cyclic amp increase caused by 1.10(-5) m dopamine was 2.3 +/- 0.9.10(-6) m. haloperidol did not alter basal or secretin-stimulated cyclic amp content. |
1982-12-02 |
2023-08-12 |
dog |
| N Vaysse, J Laval, C Senarens, J P Esteve, A Ribe. Dopamine-stimulated cyclic AMP and binding of [3H] dopamine in acini from dog pancreas. Biochimica et biophysica acta. vol 720. issue 4. 1982-12-02. PMID:6180776. |
the concentration of drugs necessary to inhibit specific binding of dopamine by 50% was 1.2 +/- 0.4.10(-7) m epinine, 4.1 +/- 1.8.10(-6) m fluphenazine, 8.0 +/- 1.6.10(-6) m haloperidol, 4.2 +/- 1.2.10(-6) m cis-flupenthixol, 2.7 +/- 4.0.10(-5) m trans-flupenthixol, less than 1.10(-5) m apomorphine, sulpiride, naloxone and isoproterenol. |
1982-12-02 |
2023-08-12 |
dog |
| H Takeuchi, S J Young, P M Grove. Dopaminergic terminal excitability following arrival of the nerve impulse: the influence of amphetamine and haloperidol. Brain research. vol 245. issue 1. 1982-12-02. PMID:6288195. |
haloperidol, a dopamine antagonist, increased the excitability of dopaminergic terminal fields, an effect which was also more marked earlier in the phasic interval. |
1982-12-02 |
2023-08-12 |
rat |
| H Takeuchi, S J Young, P M Grove. Dopaminergic terminal excitability following arrival of the nerve impulse: the influence of amphetamine and haloperidol. Brain research. vol 245. issue 1. 1982-12-02. PMID:6288195. |
variations in dopaminergic terminal excitability after impulse arrival, and the effects of amphetamine and haloperidol on this phenomenon suggest that terminal excitability is determined by events related to arrival of the nerve impulse including activation of presynaptic 'autoreceptors' by dopamine released from the synaptic ending. |
1982-12-02 |
2023-08-12 |
rat |
| K Tanimoto, K Maeda, K Chihar. Antagonizing effect of lithium on the development of dopamine supersensitivity in the tuberoinfundibular system. Brain research. vol 245. issue 1. 1982-12-02. PMID:6811103. |
lithium administration with haloperidol resulted in the inhibition of prl-lowering action of apomorphine at 5 days of withdrawal from haloperidol, indicating that the supersensitivity of dopamine receptors of dopamine receptors on pituitary lactotrophs were decreased by lithium. |
1982-12-02 |
2023-08-12 |
rat |
| K T Finnegan, G Ricaurte, L S Seiden, C R Schuste. Altered sensitivity to d-methylamphetamine, apomorphine, and haloperidol in rhesus monkeys depleted of caudate dopamine by repeated administration of d-methylamphetamine. Psychopharmacology. vol 77. issue 1. 1982-12-02. PMID:6812118. |
altered sensitivity to d-methylamphetamine, apomorphine, and haloperidol in rhesus monkeys depleted of caudate dopamine by repeated administration of d-methylamphetamine. |
1982-12-02 |
2023-08-12 |
monkey |
| M Memo, W Lovenberg, I Hanbaue. Agonist-induced subsensitivity of adenylate cyclase coupled with a dopamine receptor in slices from rat corpus striatum. Proceedings of the National Academy of Sciences of the United States of America. vol 79. issue 14. 1982-12-02. PMID:6956874. |
this loss in dopamine-stimulated enzyme activity appears to be mediated by a persistent occupancy of recognition sites of the d-1 receptor because: (i) at 10 microm, skf 38393, a selective d-1 receptor agonist, facilitates desensitization and ly 141865, a selective d-2 receptor agonist, fails to elicit desensitization of dopamine-dependent adenylate cyclase; and (ii) preincubation with dopamine in the presence of 1 microm haloperidol but not 1 microm sulpiride curtails the desensitization of dopamine-dependent adenylate cyclase. |
1982-12-02 |
2023-08-12 |
rat |
| R W Fuller, K W Perry, S K Hemrick-Lueck. Depletion of epinephrine in rat hypothalamus by a dopamine agonist, pergolide. Neurochemical research. vol 7. issue 4. 1982-10-29. PMID:6125905. |
the pergolide-induced decrease in hypothalamic epinephrine concentration was prevented by pretreatment with haloperidol or spiperone, antagonists of dopamine receptors. |
1982-10-29 |
2023-08-12 |
rat |
| J S de Belleroche, M J Nea. The contrasting effects of neuroleptics on transmitter release from the nucleus accumbens and corpus striatum. Neuropharmacology. vol 21. issue 6. 1982-10-29. PMID:6125910. |
the effects of haloperidol, chlorpromazine and clozapine on transmitter release have been studied by measuring the simultaneous release of dopamine and acetylcholine from tissue slices of nucleus accumbens and striatum in vitro following in vivo drug application, either a single dose or daily for periods of up to 25 days. |
1982-10-29 |
2023-08-12 |
Not clear |
| J S de Belleroche, M J Nea. The contrasting effects of neuroleptics on transmitter release from the nucleus accumbens and corpus striatum. Neuropharmacology. vol 21. issue 6. 1982-10-29. PMID:6125910. |
the evoked release of preloaded [14c]dopamine from either nucleus accumbens or striatum was unaffected by treatment with haloperidol. |
1982-10-29 |
2023-08-12 |
Not clear |
| H Milon, A McRae-Degueurc. Pharmacological investigation on the role of dopamine in the rat locus coeruleus. Neuroscience letters. vol 30. issue 3. 1982-10-29. PMID:6810240. |
the role of dopamine (da) in the rat locus coeruleus (lc) was investigated by determining the levels of 3,4-dihydroxyphenylacetic acid (dopac), da and noradrenaline (na) in the lc after pharmacological treatments by pargyline, haloperidol, 6-hydroxydopamine (6-ohda) and desmethylimipramine (dmi). |
1982-10-29 |
2023-08-12 |
rat |
| W R Millington, R J Wurtma. Choline and physostigmine enhance haloperidol-induced HVA and DOPAC accumulation. European journal of pharmacology. vol 80. issue 4. 1982-10-29. PMID:7106193. |
we observe that the concurrent administration to rats of cholinergic agonists and haloperidol, a dopamine receptor antagonist, produces a synergistic acceleration in striatal dopamine turnover. |
1982-10-29 |
2023-08-12 |
rat |