| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P B Zanzonico, R E Bigler, B Schmal. Neuroleptic binding sites: specific labeling in mice with [18F]haloperidol, a potential tracer for positron emission tomography. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 24. issue 5. 1983-06-10. PMID:6132964. |
the high brain concentrations and the unexpectedly high striatum-to-cerebellum concentration ratios (greater than 4 at haloperidol doses less than or equal to 1 microgram/kg) suggest that [18f]haloperidol warrants further investigation as a potential radiotracer for dopamine receptors. |
1983-06-10 |
2023-08-12 |
mouse |
| B A McMillen, C C McDonal. Selective effects of buspirone and molindone on dopamine metabolism and function in the striatum and frontal cortex of the rat. Neuropharmacology. vol 22. issue 3. 1983-06-10. PMID:6133232. |
in contrast to haloperidol, which elevates dopamine metabolism in the striatum and frontal cortex, both molindone and buspirone elicited little change in dopamine metabolism in the frontal cortex at doses up to 3.0 mg/kg, which cause the same maximal response in the corpus striatum as does haloperidol. |
1983-06-10 |
2023-08-12 |
rat |
| B A McMillen, C C McDonal. Selective effects of buspirone and molindone on dopamine metabolism and function in the striatum and frontal cortex of the rat. Neuropharmacology. vol 22. issue 3. 1983-06-10. PMID:6133232. |
this effect does not require presynaptic dopamine as catalepsy was reversed by buspirone in the dopamine-depleted rat (with 2.0 mg/kg r04-1284) as well as after postsynaptic dopamine receptor blockade by haloperidol of cis-flupenthixol. |
1983-06-10 |
2023-08-12 |
rat |
| C Forster, G M Drew, A Hilditch, E T Whalle. Dopamine receptors in human basilar arteries. European journal of pharmacology. vol 87. issue 2-3. 1983-06-10. PMID:6573262. |
(+)-butaclamol, cis-alpha-flupenthixol, fluphenazine and haloperidol competitively antagonised the relaxant effects of dopamine, but sulpiride was ineffective in concentrations as high as 1.3 x 10(-4) m. these findings show that the dopamine receptors in the human basilar artery closely resemble those in the smooth muscle of the rabbit isolated mesenteric and splenic arteries, and the dog renal and mesenteric arteries in vivo, but differ from those located presynaptically on sympathetic nerve terminals. |
1983-06-10 |
2023-08-12 |
human |
| G Stock, P Kummer, H Stumpf, K Zenner, V Stur. Involvement of dopamine in amygdaloid kindling. Experimental neurology. vol 80. issue 2. 1983-06-10. PMID:6840249. |
pharmacological manipulations of dopamine receptors (haloperidol, apomorphine) did not modify the kindling procedure. |
1983-06-10 |
2023-08-12 |
Not clear |
| P D Gluckman, S Leisti, S L Kaplan, M M Grumbac. Hormone ontogeny in the ovine fetus. XV. Studies of adenohypophysial hormones after fetal pituitary stalk section: evidence for an extrahypothalamic dopaminergic influence on fetal prolactin secretion. Endocrinology. vol 112. issue 5. 1983-05-27. PMID:6403331. |
the administration of a dopamine antagonist, haloperidol, to the ovine fetus in late gestation elevates plasma concentrations of prl, suggesting tonic dopaminergic inhibition of fetal prl secretion. |
1983-05-27 |
2023-08-12 |
Not clear |
| C E Leprohon, J K Blusztajn, R J Wurtma. Dopamine stimulation of phosphatidylcholine (lecithin) biosynthesis in rat brain neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 80. issue 7. 1983-05-27. PMID:6572961. |
stimulation by dopamine, which is observed at concentrations as low as 1 microm, is blocked by haloperidol. |
1983-05-27 |
2023-08-12 |
rat |
| A V Maricq, R M Churc. The differential effects of haloperidol and methamphetamine on time estimation in the rat. Psychopharmacology. vol 79. issue 1. 1983-05-05. PMID:6403957. |
since methamphetamine releases several catecholamines, including dopamine, and haloperidol blocks dopamine receptors, it is plausible that the horizontal location of the psychometric function (the speed of the clock) is related to the effective level of dopamine. |
1983-05-05 |
2023-08-12 |
rat |
| I Goodman, J Zacny, A Osman, A Azzaro, C Donova. Dopaminergic nature of feeding-induced behavioral stereotypies in stressed pigeons. Pharmacology, biochemistry, and behavior. vol 18. issue 2. 1983-05-05. PMID:6682226. |
dopamine dependence of feeding-induced behavioral stereotypies (fibs) was demonstrated by fibs facilitation following chronic treatment with a dopamine (da) agonist, apomorphine, and by fibs inhibition following the administration of haloperidol, a da antagonist. |
1983-05-05 |
2023-08-12 |
Not clear |
| C P Phelps, L Korányi, V Tamás. Brain catecholamine concentration during the first week of development in rats. Developmental neuroscience. vol 5. issue 5-6. 1983-04-15. PMID:7160315. |
neonatal brain (whole brain minus cerebral hemispheres) dopamine (da) and norepinephrine (ne) concentrations (pg/microgram protein) were studied 30 min after an injection of l-dopa methyl ester (50 mg/kg); haloperidol (1 mg/kg); d-amphetamine sulfate (0.5 mg/kg); saline only or no treatment. |
1983-04-15 |
2023-08-12 |
rat |
| P J Bédard, F Malouin, T Dipaolo, F Labri. Estradiol, TRH and striatal dopaminergic mechanisms. Progress in neuro-psychopharmacology & biological psychiatry. vol 6. issue 4-6. 1983-04-07. PMID:6819600. |
the effect of dopamine but not that of trh is blocked by prior administration of haloperidol indicating that although trh has a dopamine-like action in the caudate nucleus, it is not mediated via the dopamine terminals or the dopamine receptors. |
1983-04-07 |
2023-08-12 |
rat |
| F J White, R Y Wan. Comparison of the effects of chronic haloperidol treatment on A9 and A10 dopamine neurons in the rat. Life sciences. vol 32. issue 9. 1983-04-07. PMID:6827927. |
comparison of the effects of chronic haloperidol treatment on a9 and a10 dopamine neurons in the rat. |
1983-04-07 |
2023-08-12 |
rat |
| F J White, R Y Wan. Comparison of the effects of chronic haloperidol treatment on A9 and A10 dopamine neurons in the rat. Life sciences. vol 32. issue 9. 1983-04-07. PMID:6827927. |
the effects of chronic haloperidol (chal) treatment on a9 and a10 dopamine (da) neurons were compared using extracellular single cell recording techniques. |
1983-04-07 |
2023-08-12 |
rat |
| F Nicoletti, G Clementi, A Prato, P L Canonico, L Rampello, F Patti, R M Di Giorgio, U Scapagnin. Effects of hyper- and hypoprolactinemia on glutamate decarboxylase activity in medial basal hypothalamus of male rat. Neuroendocrinology. vol 36. issue 1. 1983-04-07. PMID:6828202. |
haloperidol, sulpiride, domperidone and apomorphine, drugs which influence dopamine (da) receptors and in turn prolactin (prl) secretion have been shown to induce parallel changes in medial basal hypothalamic (mbh) glutamate decarboxylase (gad) activity and serum prl levels. |
1983-04-07 |
2023-08-12 |
rat |
| R B Rastogi, S K Rastogi, Y D Lapierre, R L Singha. Bromocriptine-induced changes in dopamine and gamma aminobutyric acid in haloperidol withdrawn rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 6. issue 4-6. 1983-04-07. PMID:6891811. |
bromocriptine-induced changes in dopamine and gamma aminobutyric acid in haloperidol withdrawn rats. |
1983-04-07 |
2023-08-12 |
rat |
| F P Nijkamp, J M van Ree, J G Nijssen, M Versluis, D de Wie. Opposite interactions between alpha- and beta-endorphin fragments with dopamine mediated responses on the rat rectum in vitro. Naunyn-Schmiedeberg's archives of pharmacology. vol 321. issue 3. 1983-03-24. PMID:6185856. |
the atypical neuroleptics oxypertine, sulpiride, and clozapine, the classic neuroleptic haloperidol and metoclopramide have a similar action to de gamma e. the peptides and atypical neuroleptics do not affect the dopamine response per se while the classic neuroleptics haloperidol and metoclopramide enhance the dopamine response. |
1983-03-24 |
2023-08-12 |
rat |
| M Donowitz, G Elta, L Battisti, R Fogel, E Label-Schwart. Effect of dopamine and bromocriptine on rat ileal and colonic transport. Stimulation of absorption and reversal of cholera toxin-induced secretion. Gastroenterology. vol 84. issue 3. 1983-03-17. PMID:6295870. |
haloperidol, a specific dopamine antagonist, and yohimbine, an alpha 2-adrenergic antagonist, inhibited the effect of dopamine in ileal absorption; both antagonists alone had no effect on basal water transport. |
1983-03-17 |
2023-08-12 |
rat |
| T Teranishi, K Negishi, S Kat. Dopamine modulates S-potential amplitude and dye-coupling between external horizontal cells in carp retina. Nature. vol 301. issue 5897. 1983-03-17. PMID:6401844. |
these effects have been attributed to the action of da on horizontal cell membrane resistance, particularly at the gap junctions, and our present study on the carp retina agrees with this in showing that da also restricts intracellular lucifer yellow (ly) to single injected horizontal cells, an effect, like those of da on the s-potentials, which is antagonized by the dopamine blocker haloperidol. |
1983-03-17 |
2023-08-12 |
Not clear |
| Y Ishii, I Takayanag. Effects of some ergot alkaloids on dopamine receptors of molluscan smooth muscle. Journal of pharmacobio-dynamics. vol 5. issue 9. 1983-03-17. PMID:7153848. |
haloperidol, a competitive dopamine antagonist, shifted the dose response curves of ergot alkaloids, but methysergide did not. |
1983-03-17 |
2023-08-12 |
Not clear |
| R Pokras, B Tabakof. On the mechanism by which dopamine inhibits prolactin release in the anterior pituitary. Life sciences. vol 31. issue 23. 1983-03-17. PMID:7154854. |
haloperidol, however, reversed both the muscimol and dopamine induced inhibition of prolactin release. |
1983-03-17 |
2023-08-12 |
mouse |