| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L F Agnati, K Fuxe, F Benfenati, N Battistini, I Zini, G Toffan. Chronic ganglioside treatment counteracts the biochemical signs of dopamine receptor supersensitivity induced by chronic haloperidol treatment. Neuroscience letters. vol 40. issue 3. 1984-01-07. PMID:6646502. |
the present results therefore indicate that chronic gm1 treatment can partially counteract the increase in the number of dopamine receptors having a high affinity for neuroleptics (d2 type) induced by chronic haloperidol treatment in striatal membranes, and therefore may also partially counteract the development of neuroleptic-induced dopamine receptor supersensitivity. |
1984-01-07 |
2023-08-12 |
rat |
| V Cuomo, F Cattabeni, G Racagn. The influence of early postnatal treatment with haloperidol on the effects induced by small and large doses of apomorphine on locomotion of adult rats. Neuropharmacology. vol 22. issue 9. 1983-12-21. PMID:6633823. |
the differential ontogeny of dopamine auto- and postsynaptic receptors could be partly responsible for the different influence of postnatal treatment with haloperidol on the responsiveness of the adult to small and large doses of apomorphine. |
1983-12-21 |
2023-08-12 |
rat |
| S Jackson, P J Lowr. Secretion of pro-opiocortin peptides from isolated perfused rat pars intermedia cells. Neuroendocrinology. vol 37. issue 4. 1983-12-20. PMID:6138722. |
dopamine (da) caused a dose-dependent (10(-9)-10(-5) m) simultaneous inhibition of peptide release which was antagonised by haloperidol. |
1983-12-20 |
2023-08-12 |
rat |
| R D Huffman, M K Tick. The effects of chronic haloperidol administration on GABA receptor binding. Pharmacology, biochemistry, and behavior. vol 19. issue 2. 1983-12-20. PMID:6314387. |
these observations suggest that blockade of dopamine receptors in the striatum by haloperidol results in a compensatory decrease in the activity of the gabaergic strionigral system that leads to an increase in the number of gaba binding sites within the substantia nigra. |
1983-12-20 |
2023-08-12 |
rat |
| I M McIntyre, C Kuhn, S Demitriou, F R Fucek, M Stanle. Modulating role of lithium on dopamine turnover, prolactin release, and behavioral supersensitivity following haloperidol and reserpine. Psychopharmacology. vol 81. issue 2. 1983-12-20. PMID:6415746. |
modulating role of lithium on dopamine turnover, prolactin release, and behavioral supersensitivity following haloperidol and reserpine. |
1983-12-20 |
2023-08-12 |
rat |
| I M McIntyre, C Kuhn, S Demitriou, F R Fucek, M Stanle. Modulating role of lithium on dopamine turnover, prolactin release, and behavioral supersensitivity following haloperidol and reserpine. Psychopharmacology. vol 81. issue 2. 1983-12-20. PMID:6415746. |
concomitant administration of a chronic regimen of haloperidol and lithium did not prevent the development of tolerance as noted by dopamine metabolites in the striatum or olfactory tuberculum. |
1983-12-20 |
2023-08-12 |
rat |
| C Le Douarin, A Oblin, D Fage, B Scatto. Influence of lithium on biochemical manifestations of striatal dopamine target cell supersensitivity induced by prolonged haloperidol treatment. European journal of pharmacology. vol 93. issue 1-2. 1983-12-20. PMID:6628547. |
influence of lithium on biochemical manifestations of striatal dopamine target cell supersensitivity induced by prolonged haloperidol treatment. |
1983-12-20 |
2023-08-12 |
rat |
| C Le Douarin, A Oblin, D Fage, B Scatto. Influence of lithium on biochemical manifestations of striatal dopamine target cell supersensitivity induced by prolonged haloperidol treatment. European journal of pharmacology. vol 93. issue 1-2. 1983-12-20. PMID:6628547. |
the effects of prolonged treatment with dietary lithium and/or haloperidol (infused by means of osmotic minipumps) on biochemical parameters indicative of striatal dopamine target cell supersensitivity have been investigated in the rat. |
1983-12-20 |
2023-08-12 |
rat |
| C Le Douarin, A Oblin, D Fage, B Scatto. Influence of lithium on biochemical manifestations of striatal dopamine target cell supersensitivity induced by prolonged haloperidol treatment. European journal of pharmacology. vol 93. issue 1-2. 1983-12-20. PMID:6628547. |
when given concomitantly with haloperidol, lithium failed to prevent the fall of striatal dopamine metabolites observed 2 days following withdrawal and the tolerance to the elevation of dopamine metabolites in response to challenge with the neuroleptic during withdrawal. |
1983-12-20 |
2023-08-12 |
rat |
| V M Briukhano. [Effect of dopamine on transport of organic substances in dog kidneys]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 69. issue 8. 1983-12-20. PMID:6628754. |
dopamine exerted some direct effect on the transport of glucose, which effect can be blocked with haloperidol. |
1983-12-20 |
2023-08-12 |
dog |
| M Krug, A N Chepkova, C Geyer, T Ot. Aminergic blockade modulates long-term potentiation in the dentate gyrus of freely moving rats. Brain research bulletin. vol 11. issue 1. 1983-12-17. PMID:6138128. |
long-term potentiation (ltp) was induced in the dentate gyrus of freely moving rats by tetanic stimulation of the medial entorhinal cortex under conditions of catecholamine depletion by 200 mg/kg alpha-methyl-para-tyrosine (ampt) or blockade of alleged dopamine receptors by 0.5 mg/kg haloperidol. |
1983-12-17 |
2023-08-12 |
rat |
| O B Kuz'min, R A Kriukov. [Role of prostaglandin, the kallikrein-kinin system and renal dopamine receptors in the mechanism of the natriuretic action of the beta-adrenoblocker obzidan]. Farmakologiia i toksikologiia. vol 46. issue 5. 1983-12-17. PMID:6195013. |
the dopamine blocker haloperidol prevented the hemodynamic shift in the cortical and in the external medullary layers and interfered with the inhibitory action of obsidan in tubular sodium transport. |
1983-12-17 |
2023-08-12 |
rat |
| E O Bragin, N N Batueva, R A Durinia. [Role of the somatic monoaminergic systems in the mechanisms of regulation of pain sensitivity during reflex stimulation]. Biulleten' eksperimental'noi biologii i meditsiny. vol 96. issue 10. 1983-12-17. PMID:6313093. |
inhibition of dopamine receptors by haloperidol produced a decrease in the stress- and aea-induced analgesia. |
1983-12-17 |
2023-08-12 |
rat |
| K Fujisaw. Effects of dopamine on neuromuscular transmission in the guinea-pig mesenteric artery. European journal of pharmacology. vol 92. issue 1-2. 1983-12-17. PMID:6313381. |
in the presence of haloperidol or sulpiride (10(-5) m), dopamine (10(-6) m) did not suppress the amplitude of the e.j.p. |
1983-12-17 |
2023-08-12 |
Not clear |
| A Reches, R H Wagner, V Jackson, E Yablonskaya-Alter, S Fah. Dopamine receptors in the denervated striatum: further supersensitivity by chronic haloperidol treatment. Brain research. vol 275. issue 1. 1983-12-17. PMID:6414646. |
dopamine receptors in the denervated striatum: further supersensitivity by chronic haloperidol treatment. |
1983-12-17 |
2023-08-12 |
Not clear |
| A M Zharkovskiĭ, A V Beliako. [Effect of varying the dose of haloperidol during its prolonged administration on the development of tolerance and hypersensitivity in dopamine receptors]. Farmakologiia i toksikologiia. vol 46. issue 5. 1983-12-17. PMID:6628655. |
[effect of varying the dose of haloperidol during its prolonged administration on the development of tolerance and hypersensitivity in dopamine receptors]. |
1983-12-17 |
2023-08-12 |
mouse |
| A M Zharkovskiĭ, A V Beliako. [Effect of varying the dose of haloperidol during its prolonged administration on the development of tolerance and hypersensitivity in dopamine receptors]. Farmakologiia i toksikologiia. vol 46. issue 5. 1983-12-17. PMID:6628655. |
it has been shown in experiments on male mice that prolonged administration (for 20 days) of haloperidol in doses of 0.1, 1.0, 5.0 and 10.00 mg/kg produced an increase in the tolerance to thecataleptogenic effect at the end of administration and a rise in 3h-spiroperidole binding with striatum membranes on the 5th day after discontinuation of the neuroleptic, which attests to an increase in the sensitivity of dopamine receptors. |
1983-12-17 |
2023-08-12 |
mouse |
| A M Zharkovskiĭ, A V Beliako. [Effect of varying the dose of haloperidol during its prolonged administration on the development of tolerance and hypersensitivity in dopamine receptors]. Farmakologiia i toksikologiia. vol 46. issue 5. 1983-12-17. PMID:6628655. |
variation of haloperidol dose every other three days during 20 days of drug administration (1.0--0.1 ... 1.0 mg/kg and 1.0--10.00 ... 1.0 mg/kg) eliminated the manifestations of tolerance and hypersensitivity of dopamine receptors. |
1983-12-17 |
2023-08-12 |
mouse |
| L A Kamal, S Arbilla, A M Galzin, S Z Lange. Amphetamine inhibits the electrically evoked release of [3H]dopamine from slices of the rabbit caudate. The Journal of pharmacology and experimental therapeutics. vol 227. issue 2. 1983-12-17. PMID:6631724. |
the dopamine receptor antagonists, haloperidol and sulpiride, were not able to antagonize the inhibition by amphetamine of the electrically evoked release of [3h] dopamine at concentrations which effectively blocked apomorphine-induced inhibition of stimulation-evoked release of the labeled neurotransmitter. |
1983-12-17 |
2023-08-12 |
rabbit |
| J M Farah, K T Demarest, K E Moor. A comparison of domperidone and haloperidol effects on different dopaminergic neurons in the rat brain. Life sciences. vol 33. issue 16. 1983-12-17. PMID:6633157. |
domperidone, a dopamine (da) receptor antagonist with reportedly preferential actions outside of the blood-brain barrier, and haloperidol, a centrally active da antagonist, were compared with respect to their abilities to increase the activity of dopaminergic neurons in the rat brain. |
1983-12-17 |
2023-08-12 |
rat |