| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Le Douarin, D Fage, B Scatto. Effects of cyclo (Leu-Gly) on neurochemical indices of striatal dopaminergic supersensitivity induced by prolonged haloperidol treatment. Life sciences. vol 34. issue 4. 1984-03-19. PMID:6694528. |
when given concomitantly with haloperidol (infused by means of osmotic minipumps at a rate of 2.5 micrograms/h sc) for 14 days, cyclo (leu-gly)(2 mg/kg sc once daily) failed to prevent the fall of striatal dopamine metabolites observed 2 days following withdrawal and the tolerance to the elevation of dopamine metabolites which occurs in response to challenge with the neuroleptic during withdrawal. |
1984-03-19 |
2023-08-12 |
rat |
| A D Crocker, D H Overstree. Modification of the behavioural effects of haloperidol and of dopamine receptor regulation by altered thyroid status. Psychopharmacology. vol 82. issue 1-2. 1984-03-16. PMID:6420818. |
receptor binding studies carried out on the striata from rats sacrificed 48 h after a 6-day course of chronic haloperidol (0.1 mg/kg once daily) treatment revealed a significant upregulation (increase) of dopamine receptors in the hypothyroid rats only. |
1984-03-16 |
2023-08-12 |
rat |
| N E Andén, M Grabowska-Andén, B Liljenber. Demonstration of autoreceptors on dopamine neurons in different brain regions of rats treated with gammabutyrolactone. Journal of neural transmission. vol 58. issue 3-4. 1984-03-14. PMID:6420514. |
the effects were completely inhibited by the dopamine receptor antagonist haloperidol, indicating that they were caused by stimulation of dopamine autoreceptors. |
1984-03-14 |
2023-08-12 |
rat |
| J E Häggström, L M Gunne, A Carlsson, H Wikströ. Antidyskinetic action of 3-PPP, a selective dopaminergic autoreceptor agonist, in Cebus monkeys with persistent neuroleptic-induced dyskinesias. Journal of neural transmission. vol 58. issue 3-4. 1984-03-14. PMID:6663299. |
four cebus apella monkeys with persistent dyskinetic movements induced by earlier long-term administration of haloperidol were subjected to a trial of the dyskinesia-modifying effects of a novel dopamine autoreceptor agonist 3-ppp (3[3-hydroxyphenyl]-n-n-propyl-piperidine). |
1984-03-14 |
2023-08-12 |
monkey |
| P L Wood, P S McQuade, P Etienne, S Lal, N P Nai. Differential actions of classical and atypical neuroleptics on mouse nigrostriatal neurons. Progress in neuro-psychopharmacology & biological psychiatry. vol 7. issue 4-6. 1984-03-08. PMID:6141617. |
the classical neuroleptics haloperidol, perphenazine and chlorpromazine increase both dopamine metabolism and release in the mouse striatum. |
1984-03-08 |
2023-08-12 |
mouse |
| A G Phillips, C L Broekkamp, H C Fibige. Strategies for studying the neurochemical substrates of drug reinforcement in rodents. Progress in neuro-psychopharmacology & biological psychiatry. vol 7. issue 4-6. 1984-03-08. PMID:6686695. |
conditioned reinforcement produced with intracranial microinjection of opioids into the ventral tegmental area is blocked by the dopamine antagonist haloperidol and lesions to ascending dopamine pathways. |
1984-03-08 |
2023-08-12 |
Not clear |
| M E Trulson, T Crisp, L J Henderso. Mescaline elicits behavioral effects in cats by an action at both serotonin and dopamine receptors. European journal of pharmacology. vol 96. issue 1-2. 1984-03-02. PMID:6581976. |
the characteristic behavioral effects of mescaline in cats were nearly completely blocked by pretreatment with low doses of either a specific serotonin antagonist (methysergide) or a dopamine specific antagonist (haloperidol). |
1984-03-02 |
2023-08-12 |
Not clear |
| H Wachtel, W Kehr, G Saue. Central antidopaminergic properties of 2-bromolisuride, an analogue of the ergot dopamine agonist lisuride. Life sciences. vol 33. issue 26. 1984-03-02. PMID:6607392. |
2-bromolisuride (2-br-lis), a derivative of the ergot dopamine (da) agonist lisuride, was investigated in rodents in comparison with the da antagonist haloperidol with regard to its influence on da related behaviour, cerebral da metabolism and prolactin (prl) secretion. |
1984-03-02 |
2023-08-12 |
mouse |
| R J Jensen, N W Da. Towards an understanding of the role of dopamine in the mammalian retina. Vision research. vol 23. issue 11. 1984-02-24. PMID:6659376. |
we investigated the effects of the dopamine antagonists haloperidol and fluphenazine on the receptive field properties of rabbit ganglion cells. |
1984-02-24 |
2023-08-12 |
rabbit |
| D T Wong, F P Bymaster, L R Reid, R W Fuller, K W Perry, E C Kornfel. Effect of a stereospecific D2-dopamine agonist on acetylcholine concentration in corpus striatum of rat brain. Journal of neural transmission. vol 58. issue 1-2. 1984-02-15. PMID:6655467. |
the elevation of striatal acetylcholine levels by ly156258 was mimicked by pergolide, a dopamine agonist, and was totally prevented by pretreatment with haloperidol, a dopamine antagonist. |
1984-02-15 |
2023-08-12 |
rat |
| D E Sternberg, M B Bowers, G R Heninger, D S Charne. Lithium prevents adaptation of brain dopamine systems to haloperidol in schizophrenic patients. Psychiatry research. vol 10. issue 2. 1984-02-14. PMID:6581492. |
lithium prevents adaptation of brain dopamine systems to haloperidol in schizophrenic patients. |
1984-02-14 |
2023-08-12 |
Not clear |
| D E Sternberg, M B Bowers, G R Heninger, D S Charne. Lithium prevents adaptation of brain dopamine systems to haloperidol in schizophrenic patients. Psychiatry research. vol 10. issue 2. 1984-02-14. PMID:6581492. |
to evaluate the effect of lithium treatment on haloperidol-induced changes of brain dopamine systems, cerebrospinal fluid homovanillic acid (hva) was assessed in nine patients during a sequential treatment protocol with placebo, lithium, lithium plus acute haloperidol, and lithium plus chronic haloperidol. |
1984-02-14 |
2023-08-12 |
Not clear |
| D E Sternberg, M B Bowers, G R Heninger, D S Charne. Lithium prevents adaptation of brain dopamine systems to haloperidol in schizophrenic patients. Psychiatry research. vol 10. issue 2. 1984-02-14. PMID:6581492. |
concurrent treatment with lithium appears to prevent the development of tolerance in dopamine metabolism during chronic haloperidol treatment. |
1984-02-14 |
2023-08-12 |
Not clear |
| B Sundén-Kuronen, P Pohto, E Alane. Oral tardive dyskinesia in the rat. Acta odontologica Scandinavica. vol 41. issue 6. 1984-02-14. PMID:6581673. |
in the present experiments, rats were pretreated daily with haloperidol for 3 weeks to cause a 'chronic' blockade in the striatal dopamine receptors. |
1984-02-14 |
2023-08-12 |
human |
| C Jue. Pre- and postsynaptic effects of dopamine antagonists on dopaminergic synaptic transmission in Helix pomatia. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 76. issue 1. 1984-01-27. PMID:6139250. |
the rate of transmitter mobilization in identified dopaminergic synapses was decreased by the dopamine antagonists pimozide, chlorpromazine, haloperidol, cis-flupenthixol, curare, clozapine and high concentrations of ergometrine. |
1984-01-27 |
2023-08-12 |
Not clear |
| N E Andén, M Grabowska-Andén, B Liljenber. On the presence of autoreceptors on dopamine neurons in different brain regions. Journal of neural transmission. vol 57. issue 3. 1984-01-27. PMID:6139410. |
these inhibitory actions of b-ht 920 were almost completely reversed by the dopamine receptor antagonist haloperidol, indicating that they were caused by a stimulation of dopamine autoreceptors. |
1984-01-27 |
2023-08-12 |
rat |
| N E Andén, M Grabowska-Andén, B Liljenber. On the presence of autoreceptors on dopamine neurons in different brain regions. Journal of neural transmission. vol 57. issue 3. 1984-01-27. PMID:6139410. |
in the caudal cortex and the cerebellum, the effects of b-ht 920 and haloperidol were less clear, perhaps due to a low concentration of dopamine and to the occurrence of this dopamine in both dopamine and noradrenaline neurons. |
1984-01-27 |
2023-08-12 |
rat |
| N E Andén, M Grabowska-Andén, B Liljenber. On the presence of autoreceptors on dopamine neurons in different brain regions. Journal of neural transmission. vol 57. issue 3. 1984-01-27. PMID:6139410. |
in the hypothalamus, b-ht 920 and haloperidol did not change the alpha-methyltyrosine-induced disappearance of dopamine in agreement with previous findings that the tubero-infundibular dopamine neurons are not regulated via dopamine receptors. |
1984-01-27 |
2023-08-12 |
rat |
| N Montanaro, A Vaccheri, R Dall'Olio, O Gandolf. Time course of rat motility response to apomorphine: a simple model for studying preferential blockade of brain dopamine receptors mediating sedation. Psychopharmacology. vol 81. issue 3. 1984-01-27. PMID:6139839. |
haloperidol (0.005--0.1 mg/kg) incompletely antagonized apomorphine inhibition and markedly blocked stimulation, which suggests that it has no preferential activity on dopamine receptors subserving sedation. |
1984-01-27 |
2023-08-12 |
rat |
| H Ito, C Eyzaguirr. Effects of temperature on the response of chemoreceptor fibers to chemical agents. Brain research. vol 279. issue 1-2. 1984-01-27. PMID:6315173. |
the effects of stimulating (nacn, ach, eserine and haloperidol) and depressant (zero [ca2+]o, mecamylamine and dopamine) agents of carotid body chemoreceptors were tested at different temperatures. |
1984-01-27 |
2023-08-12 |
Not clear |