| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J F Lorden, T W McKeon, H J Baker, N Cox, S U Walkle. Characterization of the rat mutant dystonic (dt): a new animal model of dystonia musculorum deformans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 4. issue 8. 1984-09-28. PMID:6470761. |
these mutants were less sensitive than unaffected littermates to the akinesic effects of the dopamine blocker haloperidol. |
1984-09-28 |
2023-08-12 |
human |
| G C Chio. Treatment of ocular hypertension and glaucoma with dopamine antagonists. Ophthalmic research. vol 16. issue 3. 1984-09-26. PMID:6147806. |
all dopamine antagonists examined were either equipotent or more potent than beta-adrenergic blocker, timolol, to lower the iop in the following order: haloperidol greater than moperone = trifluperidol greater than clofluperol = pipamperone = lenperone = timolol. |
1984-09-26 |
2023-08-12 |
Not clear |
| K Uvnäs-Moberg, M Goiny, L E Blomquist, C E Elwi. Release of VIP-like immunoreactivity in response to dopamine agonists, insulin hypoglycemia and feeding in conscious dogs. Peptides. vol 5. issue 2. 1984-09-24. PMID:6147818. |
the release responses were abolished by pretreatment with dopamine antagonists (haloperidol 0.1 mg/kg or halopemid 0.1 mg/kg) and by hexamethonium (1 mg/kg) a blocker of ganglionic transmission. |
1984-09-24 |
2023-08-12 |
Not clear |
| A Reches, H R Wagner, A I Barkai, V Jackson, E Yablonskaya-Alter, S Fah. Electroconvulsive treatment and haloperidol: effects on pre- and postsynaptic dopamine receptors in rat brain. Psychopharmacology. vol 83. issue 2. 1984-09-20. PMID:6431465. |
electroconvulsive treatment and haloperidol: effects on pre- and postsynaptic dopamine receptors in rat brain. |
1984-09-20 |
2023-08-12 |
rat |
| C Cianchetti, C Masala, P Olivari, G Giordan. Sleep pattern alterations by naloxone. Partial prevention by haloperidol. Psychopharmacology. vol 83. issue 2. 1984-09-20. PMID:6431470. |
pretreatment with the dopamine receptor blocking agent haloperidol (2 mg intramuscularly before sleep onset) partially prevented the naloxone effect, suggesting that it is due, at least in part, to the stimulation of dopamine receptors. |
1984-09-20 |
2023-08-12 |
human |
| O V Godukhin, A D Zharikova, Budantsev AY. Role of presynaptic dopamine receptors in regulation of the glutamatergic neurotransmission in rat neostriatum. Neuroscience. vol 12. issue 2. 1984-09-14. PMID:6146947. |
haloperidol (10(-4) m) completely abolished the effects of apomorphine and beta-phenylethylamine, and partially abolished the effect of dopamine. |
1984-09-14 |
2023-08-12 |
rat |
| W C Gorospe, M E Freema. Uterus of the rat contains prolactin inhibitory activity. The American journal of physiology. vol 247. issue 2 Pt 1. 1984-09-14. PMID:6431826. |
haloperidol or bicuculline, dopaminergic and gabaergic receptor blockers, respectively, were ineffective in reversing the inhibitory effects of uterine extract on prl secretion, suggesting that the inhibition is not due to dopamine or gaba. |
1984-09-14 |
2023-08-12 |
rat |
| G Pizzolato, T T Soncrant, S I Rapopor. Haloperidol and cerebral metabolism in the conscious rat: relation to pharmacokinetics. Journal of neurochemistry. vol 43. issue 3. 1984-09-13. PMID:6540296. |
administration of the dopamine antagonist haloperidol (0.5 or 1 mg/kg). |
1984-09-13 |
2023-08-12 |
rat |
| K A Neve, C A Altar, C A Wong, J F Marshal. Quantitative analysis of [3H]spiroperidol binding to rat forebrain sections: plasticity of neostriatal dopamine receptors after nigrostriatal injury. Brain research. vol 302. issue 1. 1984-08-20. PMID:6428705. |
dopamine antagonists, such as haloperidol and butaclamol, were much more effective than dopamine agonists or the serotonin s-2 ligand, ketanserin, in inhibiting [3h]spiroperidol binding. |
1984-08-20 |
2023-08-12 |
rat |
| M J Bannon, M Goeder. Changes in substance P concentrations after protein synthesis inhibition provide an index of substance P utilization. Brain research. vol 301. issue 1. 1984-08-17. PMID:6203608. |
the administration of the dopamine antagonist haloperidol to cycloheximide-pretreated rats apparently accelerated striatonigral sp utilization, as evidenced by large depletions in spli in the substantia nigra and striatum. |
1984-08-17 |
2023-08-12 |
rat |
| V I Legeza, M G Shagoian, M F Kamynin. [Mechanism of emetic action of adrenaline and histamine in the dog]. Farmakologiia i toksikologiia. vol 47. issue 3. 1984-08-17. PMID:6734805. |
the dopamine blockers, etaperazine, haloperidol and metoclopramide given in the doses suppressing the emetic action of l-dopa do not prevent the adrenaline- and histamine-induced vomiting. |
1984-08-17 |
2023-08-12 |
dog |
| S Lahiri, N Smatresk, M Pokorski, P Barnard, A Mokashi, K H McGrego. Dopaminergic efferent inhibition of carotid body chemoreceptors in chronically hypoxic cats. The American journal of physiology. vol 247. issue 1 Pt 2. 1984-08-17. PMID:6742232. |
haloperidol, a dopamine antagonist, augmented the responses further, indicating that a part of the endogenous dopamine effect was independent of the csn efferents. |
1984-08-17 |
2023-08-12 |
Not clear |
| E R Korpi, R J Wyat. Reduced haloperidol: effects on striatal dopamine metabolism and conversion to haloperidol in the rat. Psychopharmacology. vol 83. issue 1. 1984-08-07. PMID:6204352. |
reduced haloperidol: effects on striatal dopamine metabolism and conversion to haloperidol in the rat. |
1984-08-07 |
2023-08-12 |
rat |
| E R Korpi, R J Wyat. Reduced haloperidol: effects on striatal dopamine metabolism and conversion to haloperidol in the rat. Psychopharmacology. vol 83. issue 1. 1984-08-07. PMID:6204352. |
acute injection of rats with either haloperidol or reduced haloperidol (1 mg/kg, ip) greatly increased the striatal concentrations of the acidic dopamine metabolites, indicating enhanced turnover of dopamine. |
1984-08-07 |
2023-08-12 |
rat |
| J Weiss, M L Thompson, L Shuste. Effects of naloxone and naltrexone on drug-induced hypothermia in mice. Neuropharmacology. vol 23. issue 5. 1984-08-01. PMID:6738824. |
the dopamine supersensitivity resulting from chronic treatment with haloperidol potentiated the hypothermic response to apomorphine but not to morphine. |
1984-08-01 |
2023-08-12 |
mouse |
| R D Pinnoc. The actions of antipsychotic drugs on dopamine receptors in the rat substantia nigra. British journal of pharmacology. vol 81. issue 4. 1984-07-18. PMID:6144343. |
the inhibitory effects of dopamine were antagonized by (-)-sulpiride (pa2 7.5), haloperidol (pa2 8.4) and cis-flupenthixol (pa2 6.9). |
1984-07-18 |
2023-08-12 |
rat |
| L R Sterank. Effects of antipsychotic drugs on the long-term effects of amphetamine on nigro-striatal dopamine neurons in iprindole-treated rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 325. issue 3. 1984-07-18. PMID:6145099. |
the decrease in striatal dopamine (da) at 1 week after the administration of a single injection of (+)-amphetamine sulfate (9.2 mg/kg) to iprindole-treated (10 mg/kg of iprindole hydrochloride) rats was prevented by haloperidol (0.2 mg/kg), sulpiride (32 mg/kg), pimozide (2 mg/kg), chlorpromazine hydrochloride (3.5 mg/kg), fluphenazine 2-hydrochloride (0.25 mg/kg) and (+)-butaclamol hydrochloride (1 mg/kg) but not by (-)-butaclamol hydrochloride (1 mg/kg) or clozapine (40 mg/kg). |
1984-07-18 |
2023-08-12 |
rat |
| G Fontani, F Farabollin. Effect of DSP-4, pCPA, and haloperidol on hippocampal electrical activity and behavior in rabbits. Behavioral and neural biology. vol 40. issue 2. 1984-07-17. PMID:6233963. |
the block of dopamine receptors by chronic haloperidol administration (5 mg/kg ip/day) did not seem to exert any effect on rsa parameters. |
1984-07-17 |
2023-08-12 |
Not clear |
| B Costall, A M Domeney, R J Naylo. Long-term consequences of antagonism by neuroleptics of behavioural events occurring during mesolimbic dopamine infusion. Neuropharmacology. vol 23. issue 3. 1984-07-12. PMID:6145111. |
it is concluded that the long-term consequences (up to 1 year) of a brief period (13 days) of overactivity induced by mesolimbic infusion of dopamine cannot be prevented by daily treatment with haloperidol or sulpiride in doses adequate to prevent the behavioural expression of the effects of the dopamine stimulation during its infusion. |
1984-07-12 |
2023-08-12 |
rat |
| M Kemali, N Milici, D Kemal. Drugs and the frog retina. Effect of dopaminergic agents on the pigment screening of light- and dark-adapted frogs. Neuropharmacology. vol 23. issue 3. 1984-07-12. PMID:6610134. |
this is a study, using the light and electron microscope, of the action of a dopamine agonist (apomorphine) and of a dopamine antagonist (haloperidol) on the retinal pigment screening (ps) of light- and dark-adapted frogs. |
1984-07-12 |
2023-08-12 |
Not clear |