Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
J Hytte. Functional evidence for selective dopamine D-1 receptor blockade by SCH 23390. Neuropharmacology. vol 23. issue 12A. 1985-04-17. PMID:6152023. |
in contrast to haloperidol, a specific dopamine d-2 antagonist, which inhibited the decline in release of both ligands from preloaded slices induced by apomorphine, sch 23390 was without effect on this release from slices loaded with [3h]dopamine but had effect on release from slices loaded with [3h]choline, in concentrations 350 times greater than those of haloperidol (ic50 = 0.63 microm). |
1985-04-17 |
2023-08-12 |
rat |
J Agut, I L Coviella, R J Wurtma. Cytidine(5')diphosphocholine enhances the ability of haloperidol to increase dopamine metabolites in the striatum of the rat and to diminish stereotyped behavior induced by apomorphine. Neuropharmacology. vol 23. issue 12A. 1985-04-17. PMID:6543245. |
cytidine(5')diphosphocholine enhances the ability of haloperidol to increase dopamine metabolites in the striatum of the rat and to diminish stereotyped behavior induced by apomorphine. |
1985-04-17 |
2023-08-12 |
rat |
J Agut, I L Coviella, R J Wurtma. Cytidine(5')diphosphocholine enhances the ability of haloperidol to increase dopamine metabolites in the striatum of the rat and to diminish stereotyped behavior induced by apomorphine. Neuropharmacology. vol 23. issue 12A. 1985-04-17. PMID:6543245. |
stereotyped behavior was measured during the hour after administration of apomorphine; levels of the dopamine metabolites, homovanillic acid (hva) and 3,4-dihydroxyphenylacetic acid (dopac) in the striatum were assessed at the end of this period (2 hr after administration of haloperidol). |
1985-04-17 |
2023-08-12 |
rat |
S L Moo. Prenatal haloperidol alters striatal dopamine and opiate receptors. Brain research. vol 323. issue 1. 1985-04-16. PMID:6098328. |
prenatal haloperidol alters striatal dopamine and opiate receptors. |
1985-04-16 |
2023-08-12 |
Not clear |
S L Moo. Prenatal haloperidol alters striatal dopamine and opiate receptors. Brain research. vol 323. issue 1. 1985-04-16. PMID:6098328. |
dopamine receptors were chronically blocked with haloperidol during prenatal development. |
1985-04-16 |
2023-08-12 |
Not clear |
S L Moo. Prenatal haloperidol alters striatal dopamine and opiate receptors. Brain research. vol 323. issue 1. 1985-04-16. PMID:6098328. |
the differential effect of haloperidol on the density and developmental time course of the dopamine and non-dopamine systems suggests that complex developmental interactions normally occur, and that these can be disrupted by maternal administration of neuroleptic drugs. |
1985-04-16 |
2023-08-12 |
Not clear |
S H Chandler, L J Goldber. Differentiation of the neural pathways mediating cortically induced and dopaminergic activation of the central pattern generator (CPG) for rhythmical jaw movements in the anesthetized guinea pig. Brain research. vol 323. issue 2. 1985-04-15. PMID:6525515. |
it was shown that apo induced rjms required an intact superior colliculus, and were blocked by low doses (0.05-1.0 mg/kg) of haloperidol (hal), a dopamine antagonist. |
1985-04-15 |
2023-08-12 |
Not clear |
A D Zharikova, O V Godukhi. [Presynaptic autoregulation of dopamine release]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 71. issue 1. 1985-04-11. PMID:2982672. |
haloperidol (10(-6) m) abolishes the inhibitory effect of exogenous dopamine. |
1985-04-11 |
2023-08-11 |
rat |
I Vermes, F J Tilders, J C Stoo. Dopamine inhibits the release of immunoreactive beta-endorphin from rat hypothalamus in vitro. Brain research. vol 326. issue 1. 1985-04-08. PMID:3155984. |
the dopamine receptor blocking agent haloperidol prevents this inhibitory effect of dopamine. |
1985-04-08 |
2023-08-11 |
rat |
H H Yeh, B A Battelle, D G Pur. Dopamine regulates synaptic transmission mediated by cholinergic neurons of the rat retina. Neuroscience. vol 13. issue 3. 1985-04-02. PMID:6098860. |
this facilitation by dopamine was reversible and could be blocked by haloperidol, a dopamine receptor antagonist. |
1985-04-02 |
2023-08-12 |
rat |
M Ishibashi, T Yamaj. Mechanism of the inhibitory action of dopamine and somatostatin on prolactin secretion from human lactotrophs in culture. The Journal of clinical endocrinology and metabolism. vol 60. issue 3. 1985-03-25. PMID:2579087. |
the inhibitory effect of dopamine on prl secretion and camp accumulation was blocked by coincubation of the cells with haloperidol. |
1985-03-25 |
2023-08-11 |
human |
N M Rupniak, S Mann, M D Hall, S Fleminger, G Kilpatrick, P Jenner, C D Marsde. Differential effects of continuous administration for 1 year of haloperidol or sulpiride on striatal dopamine function in the rat. Psychopharmacology. vol 84. issue 4. 1985-03-25. PMID:6441951. |
differential effects of continuous administration for 1 year of haloperidol or sulpiride on striatal dopamine function in the rat. |
1985-03-25 |
2023-08-12 |
rat |
N M Rupniak, S Mann, M D Hall, S Fleminger, G Kilpatrick, P Jenner, C D Marsde. Differential effects of continuous administration for 1 year of haloperidol or sulpiride on striatal dopamine function in the rat. Psychopharmacology. vol 84. issue 4. 1985-03-25. PMID:6441951. |
striatal dopamine-stimulated adenylate cyclase activity was inhibited for the 1st month of haloperidol treatment, thereafter returning to control levels; dopamine stimulation was increased after 12 months of sulpiride treatment. |
1985-03-25 |
2023-08-12 |
rat |
N M Rupniak, S Mann, M D Hall, S Fleminger, G Kilpatrick, P Jenner, C D Marsde. Differential effects of continuous administration for 1 year of haloperidol or sulpiride on striatal dopamine function in the rat. Psychopharmacology. vol 84. issue 4. 1985-03-25. PMID:6441951. |
chronic administration of sulpiride does not induce identical changes in striatal dopamine function to those caused by haloperidol. |
1985-03-25 |
2023-08-12 |
rat |
N M Rupniak, G Kilpatrick, M D Hall, P Jenner, C D Marsde. Differential alterations in striatal dopamine receptor sensitivity induced by repeated administration of clinically equivalent doses of haloperidol, sulpiride or clozapine in rats. Psychopharmacology. vol 84. issue 4. 1985-03-25. PMID:6441952. |
on continuous treatment and following withdrawal from haloperidol, sulpiride, or clozapine the ability of dopamine to stimulate striatal adenylate cyclase activity did not differ from that in control animals. |
1985-03-25 |
2023-08-12 |
rat |
G Mereu, B Fanni, M Collu, A Diena, A Glasse. Zetidoline, a novel neuroleptic, activates nigral dopaminergic neurons in rats. Life sciences. vol 36. issue 5. 1985-03-18. PMID:2857469. |
zetidoline (zet), a rather selective dopamine (da) d2-receptor blocker, was found to be equipotent to haloperidol and over 300 times as potent as sulpiride in activating the firing rate of substantia nigra dopaminergic neurons (sn-da neurons) in unanesthetized rats. |
1985-03-18 |
2023-08-11 |
rat |
W Koller, J Curtin, J Field. Molindone compared to haloperidol in a guinea-pig model of tardive dyskinesia. Neuropharmacology. vol 23. issue 10. 1985-03-14. PMID:6240609. |
chronic administration of haloperidol (0.1, 0.5 and 5.0 mg/kg) also increased both the behavioral response to apomorphine and the number of dopamine receptors. |
1985-03-14 |
2023-08-12 |
Not clear |
K B Shapovalov. [Conditioned posture changes in dogs after systemic administration of dopaminergic agents]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 34. issue 6. 1985-03-08. PMID:6098094. |
dopamine agonist l-dopa and haloperidol blocking dopamine striate receptors. |
1985-03-08 |
2023-08-12 |
Not clear |
G M Drew, A Hilditc. Prejunctional dopamine receptors modulate twitch responses to parasympathetic nerve stimulation in the rabbit isolated rectococcygeus muscle. British journal of pharmacology. vol 83. issue 4. 1985-03-05. PMID:6151412. |
the twitch-inhibitory effect of dopamine was reversed by haloperidol or sulpiride (1 x 10(-8)-1 x 10(-5)m for either) but not by phentolamine or yohimbine (up to 1 x 10(-4)m). |
1985-03-05 |
2023-08-12 |
rabbit |
G M Drew, A Hilditc. Prejunctional dopamine receptors modulate twitch responses to parasympathetic nerve stimulation in the rabbit isolated rectococcygeus muscle. British journal of pharmacology. vol 83. issue 4. 1985-03-05. PMID:6151412. |
haloperidol and sulpiride were potent, specific, competitive antagonists of the twitch-inhibitory effect of dopamine; their pa2 values were 8.39 and 7.75, respectively. |
1985-03-05 |
2023-08-12 |
rabbit |