| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L D Snell, Z L Mueller, R L Gannon, P B Silverman, K M Johnso. A comparison between classes of drugs having phencyclidine-like behavioral properties on dopamine efflux in vitro and dopamine metabolism in vivo. The Journal of pharmacology and experimental therapeutics. vol 231. issue 2. 1984-12-19. PMID:6092611. |
phencyclidine [(l-phenylcyclohexyl) piperidine] (pcp) is known to increase the basal efflux of striatal dopamine (da) in vitro and to enhance haloperidol (hal)-induced striatal da metabolism in vivo. |
1984-12-19 |
2023-08-12 |
rat |
| J H Pazo, O R Tumilasci, J H Medina, M A Dvorki. Salivary secretion induced by L-DOPA in haloperidol-treated rats. Journal of the autonomic nervous system. vol 11. issue 2. 1984-12-19. PMID:6491157. |
that chronic administration of haloperidol increases the salivary response to l-dopa and l-noradrenaline, suggests that such an affect could be due to the development of supersensitivity of striatal dopamine receptors as well as of peripheral alpha-adrenergic receptors. |
1984-12-19 |
2023-08-12 |
rat |
| C E Crosson, R W Beuerman, S D Klyc. Dopamine modulation of active ion transport in rabbit corneal epithelium. Investigative ophthalmology & visual science. vol 25. issue 11. 1984-12-12. PMID:6208162. |
this response was blocked by pretreatment with the dopamine antagonist, haloperidol, and by the elimination of cl- from the bathing solutions. |
1984-12-12 |
2023-08-12 |
rabbit |
| H Hermesh, M Huberman, H Radvan, E Kot. Recurrent neuroleptic malignant syndrome due to tiapride and haloperidol: the possible role of D-2 dopamine receptors. The Journal of nervous and mental disease. vol 172. issue 11. 1984-12-06. PMID:6238132. |
recurrent neuroleptic malignant syndrome due to tiapride and haloperidol: the possible role of d-2 dopamine receptors. |
1984-12-06 |
2023-08-12 |
Not clear |
| b' J Cortijo, J Esplugues, E J Morcillo, M Perpi\\xc3\\xb1\\xc3\\xa. Pharmacological analysis of the responsiveness of guinea-pig lung parenchymal strip to dopamine. British journal of pharmacology. vol 83. issue 1. 1984-11-28. PMID:6487886.' |
incubation with haloperidol (10(-5) m) did not modify the characteristics of the concentration-response curve to dopamine. |
1984-11-28 |
2023-08-12 |
Not clear |
| R G MacKenzie, M J Zigmon. High- and low-affinity states of striatal D2 receptors are not affected by 6-hydroxydopamine or chronic haloperidol treatment. Journal of neurochemistry. vol 43. issue 5. 1984-11-26. PMID:6208330. |
d2 receptor density was elevated by more than 40% following dopamine depletion by 6-hydroxydopamine or chronic receptor blockade by haloperidol. |
1984-11-26 |
2023-08-12 |
rat |
| A J Gower, H G Berendsen, M M Princen, C L Broekkam. The yawning-penile erection syndrome as a model for putative dopamine autoreceptor activity. European journal of pharmacology. vol 103. issue 1-2. 1984-11-20. PMID:6479232. |
haloperidol antagonised dopamine agonist-induced yawning and penile erections. |
1984-11-20 |
2023-08-12 |
rat |
| J M Tepper, S Nakamura, S J Young, P M Grove. Autoreceptor-mediated changes in dopaminergic terminal excitability: effects of striatal drug infusions. Brain research. vol 309. issue 2. 1984-11-15. PMID:6089960. |
infusions of apomorphine or amphetamine reduced terminal excitability whereas the dopamine antagonists, haloperidol, fluphenazine or sulpiride, led to increases in terminal excitability. |
1984-11-15 |
2023-08-12 |
Not clear |
| E H Lee, M A Geye. Dopamine autoreceptor mediation of the effects of apomorphine on serotonin neurons. Pharmacology, biochemistry, and behavior. vol 21. issue 2. 1984-11-15. PMID:6207549. |
together with previous findings that the serotonergic actions of systemic apo were antagonized by haloperidol or intraventricular 6-hydroxydopamine pretreatment; and the selective dopamine (da) autoreceptor agonist 3-3-hydroxyphenyl-n-n-propyl-piperidine mimicked the effects of apo on 5-ht neurons, these results suggest that the observed effects of apo on the mesostriatal serotonergic system are probably mediated through da autoreceptors in the substantia nigra and possibly by a direct nigroraphe pathway. |
1984-11-15 |
2023-08-12 |
rat |
| I Ushijima, K Yamada, T Inoue, T Tokunaga, T Furukawa, Y Nod. Muscarinic and nicotinic effects on yawning and tongue protruding in the rat. Pharmacology, biochemistry, and behavior. vol 21. issue 2. 1984-11-15. PMID:6541344. |
low dose (0.02 mg/kg) of haloperidol, which has been reported to block presynaptic dopamine autoreceptors, inhibited apomorphine-induced yawning but did not affect cholinergic agonist-induced yawning. |
1984-11-15 |
2023-08-12 |
rat |
| B Lössner, R Jork, M Lindner, B Lucke, H Matthie. Dopamine stimulated glycosylation of brain proteins in vitro is inhibited only partially by dopamine receptor antagonists. Biomedica biochimica acta. vol 43. issue 6. 1984-11-14. PMID:6148936. |
dopamine stimulated l-fucose incorporation into rat hippocampal glycoproteins was inhibited to a different degree, but almost incompletely by dopamine receptor antagonists like haloperidol, d-butaclamol, promazine and alpha-flupenthixol, whilst chloropromazine and the selective d2-receptor antagonist sulpiride were without any effects. |
1984-11-14 |
2023-08-12 |
mouse |
| B Costall, R J Naylor, C C Ta. Neuronally mediated contraction responses of guinea-pig stomach smooth muscle preparations: modification by benzamide derivatives does not reflect a dopamine antagonist action. European journal of pharmacology. vol 102. issue 1. 1984-11-13. PMID:6479220. |
the actions of the substituted benzamide derivatives metoclopramide, clebopride, ym-09151-2, tiapride, (+)- and (-)-sulpiride and (+)- and (-)-sultopride, and the dopamine antagonists haloperidol and domperidone, were studied on the responses to field stimulation (0.125-10 hz) of smooth muscle strips taken from cardia, fundus, body and antral regions of the longitudinal and circular muscle of guinea-pig stomach. |
1984-11-13 |
2023-08-12 |
Not clear |
| B Costall, R J Naylor, C C Ta. Neuronally mediated contraction responses of guinea-pig stomach smooth muscle preparations: modification by benzamide derivatives does not reflect a dopamine antagonist action. European journal of pharmacology. vol 102. issue 1. 1984-11-13. PMID:6479220. |
other dopamine antagonists, (+)- and (-)-sulpiride, (+)- and (-)-sultopride, tiapride, haloperidol and domperidone failed to facilitate contraction to field stimulation of any stomach tissue. |
1984-11-13 |
2023-08-12 |
Not clear |
| T Silverstone, S Levine, H L Freeman, A Dubin. Zetidoline, a new antipsychotic. First controlled trial in acute schizophrenia. The British journal of psychiatry : the journal of mental science. vol 145. 1984-11-09. PMID:6148118. |
zetidoline (ztd), a compound chemically unrelated to any available antipsychotic, with selective dopamine receptor-blocking properties, was compared with haloperidol (hlp) in a double-blind study on 56 in-patients who had either first episodes or acute relapses of schizophrenia. |
1984-11-09 |
2023-08-12 |
Not clear |
| N T Buu, J Duhaime, O Kuche. The bicuculline-like properties of dopamine sulfate in rat brain. Life sciences. vol 35. issue 10. 1984-11-01. PMID:6482648. |
the results showed that the convulsive effects of dopamine sulfate and of bicuculline could be abolished by gaba agonists diazepam and muscimol, but not by da antagonists haloperidol and metoclopramide. |
1984-11-01 |
2023-08-12 |
human |
| R A Felder, M Blecher, P L Calcagno, P A Jos. Dopamine receptors in the proximal tubule of the rabbit. The American journal of physiology. vol 247. issue 3 Pt 2. 1984-10-24. PMID:6476125. |
since the heterogeneity of kidney homogenates limits the interpretation of these studies, the [3h]haloperidol binding site and adenylate cyclase sensitivity to dopamine were studied in the isolated proximal convoluted tubule and pars recta of the rabbit kidney. |
1984-10-24 |
2023-08-12 |
rabbit |
| B Wilffert, G Smit, A de Jonge, M J Thoolen, P B Timmermans, P A van Zwiete. Inhibitory dopamine receptors on sympathetic neurons innervating the cardiovascular system of the pithed rat. Characterization and role in relation to presynaptic alpha 2-adrenoceptors. Naunyn-Schmiedeberg's archives of pharmacology. vol 326. issue 2. 1984-10-12. PMID:6089003. |
the inhibition exerted by dpda was blocked by haloperidol and sulpiride (0.3 mg/kg of each), but not by yohimbine (1 mg/kg), indicating the involvement of dopamine receptors. |
1984-10-12 |
2023-08-12 |
rat |
| M K Sanghera, M E Trulson, D C Germa. Electrophysiological properties of mouse dopamine neurons: in vivo and in vitro studies. Neuroscience. vol 12. issue 3. 1984-10-12. PMID:6472621. |
the dopamine agonists apomorphine and d-amphetamine, given systemically, decreased the firing rate of these neurons and the dopamine receptor blocker, haloperidol, reversed these effects. |
1984-10-12 |
2023-08-12 |
mouse |
| M K Sanghera, M E Trulson, D C Germa. Electrophysiological properties of mouse dopamine neurons: in vivo and in vitro studies. Neuroscience. vol 12. issue 3. 1984-10-12. PMID:6472621. |
the zona compacta neurons were inhibited by the micro-iontophoretic application of dopamine and gamma-aminobutyric acid, and systemic haloperidol selectively attenuated the effects of dopamine. |
1984-10-12 |
2023-08-12 |
mouse |
| M R Melis, K Gal. Intranigral application of substance P antagonists prevents the haloperidol-induced activation of striatal tyrosine hydroxylase. Naunyn-Schmiedeberg's archives of pharmacology. vol 326. issue 1. 1984-10-03. PMID:6206401. |
these results suggests that nigral substance p plays an important role in the activation of nigrostriatal dopamine neurons produced by haloperidol. |
1984-10-03 |
2023-08-12 |
rat |