| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Memo, G Sagheddu, M O Carruba, P Span. Dihydroergotoxine decreases blood pressure in spontaneously hypertensive rats by interacting with peripheral dopamine receptors. Life sciences. vol 36. issue 16. 1985-05-20. PMID:3982223. |
pharmacological characterization of the phenomenon indicated that it is mediated by stimulation of dopamine receptors, since pretreatment with haloperidol, cis-flupentixol but not with trans-flupentixol, completely prevent the reduction in blood pressure induced by dihydroergotoxine. |
1985-05-20 |
2023-08-11 |
rat |
| R L Boriso. Pharmacology of antipsychotic drugs. The Journal of clinical psychiatry. vol 46. issue 4 Pt 2. 1985-05-15. PMID:2858475. |
the so-called atypical neuroleptics show far less dopamine blocking potency in human striatum compared to haloperidol, with equal receptor blocking potency in the limbic system. |
1985-05-15 |
2023-08-11 |
human |
| A S Levine, J E Morle. Neuropeptide Y: a potent inducer of consummatory behavior in rats. Peptides. vol 5. issue 6. 1985-05-15. PMID:6549409. |
the npy induction of food intake was suppressed by the opiate antagonist, naloxone, and by the dopamine antagonist, haloperidol. |
1985-05-15 |
2023-08-12 |
rat |
| J M Farah, D Sapun-Malcolm, G P Muelle. Apomorphine selectively stimulates opiocortin hormone release from the pars distalis in rats. European journal of pharmacology. vol 107. issue 3. 1985-05-10. PMID:3156753. |
the apomorphine response was inhibited by pretreatment with either the dopamine antagonist, haloperidol (0.1 mg/kg i.p., 2 h) or the glucocorticoid, dexamethasone (50 micrograms/kg i.p., 4 h). |
1985-05-10 |
2023-08-11 |
rat |
| A K Dua, C Pinsk. delta-Opioid modulation of striatal dopaminergic activity in mice. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 12. issue 1. 1985-05-01. PMID:2983850. |
unstimulated vertical climbing activity was reduced, and all opioid-antagonist enhancement of climbing behavior was antagonized, by the competitive dopamine antagonist haloperidol in dose-related fashion. |
1985-05-01 |
2023-08-11 |
mouse |
| M Bräutigam, G Laschinski, B Kittner, H Herke. Effect of apomorphine, alpha-methylparatyrosine, haloperidol and reserpine on DOPA production in clonal cell lines (PC-12 and N1E-115). Biochemical pharmacology. vol 34. issue 7. 1985-05-01. PMID:3921032. |
reserpine and haloperidol reduced the intracellular dopamine in the pc-12 cells and simultaneously induced a blockade of cellular dopa production. |
1985-05-01 |
2023-08-11 |
Not clear |
| M Bräutigam, G Laschinski, B Kittner, H Herke. Effect of apomorphine, alpha-methylparatyrosine, haloperidol and reserpine on DOPA production in clonal cell lines (PC-12 and N1E-115). Biochemical pharmacology. vol 34. issue 7. 1985-05-01. PMID:3921032. |
this transient increase of cytoplasmic dopamine by reserpine or haloperidol brings about the inhibition of dopa production in the pc-12 cells. |
1985-05-01 |
2023-08-11 |
Not clear |
| Y Taché, D Lesiege, W Vale, R Coll. Gastric hypersecretion by intracisternal TRH: dissociation from hypophysiotropic activity and role of central catecholamine. European journal of pharmacology. vol 107. issue 2. 1985-04-26. PMID:3920055. |
blockade of dopamine receptors by intracisternal haloperidol, peripheral depletion of catecholamine by chronic treatment with guanethidine combined with acute adrenalectomy or cervical cord transection at c5 level, did not modify gastric response to trh. |
1985-04-26 |
2023-08-11 |
rat |
| E Hård, J Engel, K Larsson, B Mus. Effect of diazepam, apomorphine and haloperidol on the audiogenic immobility reaction and on the open field behavior. Psychopharmacology. vol 85. issue 1. 1985-04-26. PMID:3920692. |
weanling rats were treated with diazepam, apomorphine, and haloperidol to study the influence of the dopamine (da) system on the audiogenic immobility reaction and open field locomotory behavior. |
1985-04-26 |
2023-08-11 |
rat |
| T Zetterström, T Sharp, U Ungersted. Effect of neuroleptic drugs on striatal dopamine release and metabolism in the awake rat studied by intracerebral dialysis. European journal of pharmacology. vol 106. issue 1. 1985-04-26. PMID:6085051. |
this study investigated the effect of three neuroleptic drugs, (+/-)-sulpiride, haloperidol and cis-flupenthixol, on dopamine release and metabolism in the striatum of the awake rat. |
1985-04-26 |
2023-08-12 |
rat |
| T Zetterström, T Sharp, U Ungersted. Effect of neuroleptic drugs on striatal dopamine release and metabolism in the awake rat studied by intracerebral dialysis. European journal of pharmacology. vol 106. issue 1. 1985-04-26. PMID:6085051. |
sulpiride (10, 50 and 250 mg/kg), cis-flupenthixol (0.5 and 2 mg/kg) and haloperidol (2 mg/kg) all increased the levels of dopamine in striatal perfusates. |
1985-04-26 |
2023-08-12 |
rat |
| D J De Vries, P M Bear. Competitive inhibition of [3H]spiperone binding to D-2 dopamine receptors in striatal homogenates by organic calcium channel antagonists and polyvalent cations. European journal of pharmacology. vol 106. issue 1. 1985-04-26. PMID:6241565. |
the specific binding of [3h]spiperone (30 pm) to d-2 dopamine receptors in homogenates of the rat corpus striatum, as defined by the d-2 antagonist haloperidol (100 nm), was displaced by organic calcium channel antagonists and by polyvalent cations. |
1985-04-26 |
2023-08-12 |
rat |
| M D Tricklebank, C Forler, J R Fozar. The involvement of subtypes of the 5-HT1 receptor and of catecholaminergic systems in the behavioural response to 8-hydroxy-2-(di-n-propylamino)tetralin in the rat. European journal of pharmacology. vol 106. issue 2. 1985-04-26. PMID:6241568. |
under these circumstances blockade by the selective 5-ht2 receptor antagonist, ketanserin, and by haloperidol was not seen, and only the flat body posture was significantly reduced by prazosin, rendering a key role for 5-ht2 receptors, alpha 1-adrenoceptors and dopamine receptors unlikely. |
1985-04-26 |
2023-08-12 |
rat |
| B Costall, R J Naylor, C C Ta. The mechanism of action of dopamine to inhibit field stimulation-induced contractions of guinea pig stomach strips. Naunyn-Schmiedeberg's archives of pharmacology. vol 328. issue 2. 1985-04-19. PMID:6396519. |
that noradrenaline was approximately 10 fold more potent than dopamine, that the dopamine response was not antagonised by the dopamine antagonists haloperidol, domperidone or (-)sulpiride, but was mimicked by the alpha 2-agonist guanfacine and partially antagonised by the alpha 2-adrenoceptor antagonist yohimbine (which could also antagonise the inhibitory actions of guanfacine) would indicate that a component of dopamine's action to reduce cholinergic activity is effected via alpha 2-adrenoceptor mechanisms. |
1985-04-19 |
2023-08-12 |
Not clear |
| I Fazekas, H Medzihradszky-Schweiger, G Rappay, Z Acs, M Fekete, A Gyéva. Responsiveness of intermediate lobe cells to neural mediators in culture. Experimental and clinical endocrinology. vol 84. issue 3. 1985-04-18. PMID:6098487. |
the inhibition is probably mediated by specific dopaminergic receptors, since simultaneously added haloperidol prevented the dopamine induced hormone release inhibition. |
1985-04-18 |
2023-08-12 |
rat |
| J Hytte. Functional evidence for selective dopamine D-1 receptor blockade by SCH 23390. Neuropharmacology. vol 23. issue 12A. 1985-04-17. PMID:6152023. |
in contrast to haloperidol, a specific dopamine d-2 antagonist, which inhibited the decline in release of both ligands from preloaded slices induced by apomorphine, sch 23390 was without effect on this release from slices loaded with [3h]dopamine but had effect on release from slices loaded with [3h]choline, in concentrations 350 times greater than those of haloperidol (ic50 = 0.63 microm). |
1985-04-17 |
2023-08-12 |
rat |
| J Agut, I L Coviella, R J Wurtma. Cytidine(5')diphosphocholine enhances the ability of haloperidol to increase dopamine metabolites in the striatum of the rat and to diminish stereotyped behavior induced by apomorphine. Neuropharmacology. vol 23. issue 12A. 1985-04-17. PMID:6543245. |
cytidine(5')diphosphocholine enhances the ability of haloperidol to increase dopamine metabolites in the striatum of the rat and to diminish stereotyped behavior induced by apomorphine. |
1985-04-17 |
2023-08-12 |
rat |
| J Agut, I L Coviella, R J Wurtma. Cytidine(5')diphosphocholine enhances the ability of haloperidol to increase dopamine metabolites in the striatum of the rat and to diminish stereotyped behavior induced by apomorphine. Neuropharmacology. vol 23. issue 12A. 1985-04-17. PMID:6543245. |
stereotyped behavior was measured during the hour after administration of apomorphine; levels of the dopamine metabolites, homovanillic acid (hva) and 3,4-dihydroxyphenylacetic acid (dopac) in the striatum were assessed at the end of this period (2 hr after administration of haloperidol). |
1985-04-17 |
2023-08-12 |
rat |
| S L Moo. Prenatal haloperidol alters striatal dopamine and opiate receptors. Brain research. vol 323. issue 1. 1985-04-16. PMID:6098328. |
prenatal haloperidol alters striatal dopamine and opiate receptors. |
1985-04-16 |
2023-08-12 |
Not clear |
| S L Moo. Prenatal haloperidol alters striatal dopamine and opiate receptors. Brain research. vol 323. issue 1. 1985-04-16. PMID:6098328. |
dopamine receptors were chronically blocked with haloperidol during prenatal development. |
1985-04-16 |
2023-08-12 |
Not clear |