| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Melamed, J Rosenthal, M Globus, O Cohen, A Uzza. Suppression of MPTP-induced dopaminergic neurotoxicity in mice by nomifensine and L-DOPA. Brain research. vol 342. issue 2. 1985-11-12. PMID:3876139. |
to examine effects of various pharmacological manipulations of dopamine (da) metabolism on da neurotoxicity of n-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (mptp), c57 black mice were injected with mptp (30 mg/kg s.c., once daily for two days) alone or in combination with apomorphine, bromocriptine, haloperidol, l-dopa or nomifensine. |
1985-11-12 |
2023-08-11 |
mouse |
| L G Olson, N A Saunder. Ventilatory stimulation by dopamine-receptor antagonists in the mouse. British journal of pharmacology. vol 85. issue 1. 1985-10-23. PMID:2862937. |
the effect of combined haloperidol (90 nmol kg-1) and varying doses of phentolamine (175-900 nmol kg-1) was assessed to test the hypothesis that alpha-antagonism was a factor in determining the increase in ventilation following dopamine blockade. |
1985-10-23 |
2023-08-11 |
mouse |
| D Ivanov, D Stanev. On some presynaptic effects of an aminotetraline derivative. Acta physiologica et pharmacologica Bulgarica. vol 11. issue 1. 1985-10-18. PMID:4036649. |
both compound 1b (2 x 10(-6) m) and morphine (1 x 10(-6) m) manifest potentiated inhibitory effect on the contractile response of guinea-pig ileum, administered on the background of dopamine (1 x 10(-5) m) and haloperidol (1 x 10(-6) m). |
1985-10-18 |
2023-08-11 |
mouse |
| P Chiu, G Rajakumar, S Chiu, R L Johnson, R K Mishr. Mesolimbic and striatal dopamine receptor supersensitivity: prophylactic and reversal effects of L-prolyl-L-leucyl-glycinamide (PLG). Peptides. vol 6. issue 2. 1985-10-10. PMID:2863809. |
using the rodent model of chronic administration of the neuroleptic haloperidol, we investigated the possible desensitizing effects of a tripeptide structurally unrelated to dopamine agonists, l-prolyl-l-leucyl-glycinamide (plg) on mesolimbic and striatal dopaminergic receptor supersensitivity. |
1985-10-10 |
2023-08-11 |
Not clear |
| P Chiu, G Rajakumar, S Chiu, R L Johnson, R K Mishr. Mesolimbic and striatal dopamine receptor supersensitivity: prophylactic and reversal effects of L-prolyl-L-leucyl-glycinamide (PLG). Peptides. vol 6. issue 2. 1985-10-10. PMID:2863809. |
administration of plg either prior to or after chronic haloperidol, inhibited the supersensitivity of dopamine receptors. |
1985-10-10 |
2023-08-11 |
Not clear |
| M Kusunoki, K Taniyama, C Tanak. Dopamine regulation of [3H]acetylcholine release from guinea-pig stomach. The Journal of pharmacology and experimental therapeutics. vol 234. issue 3. 1985-10-09. PMID:2863371. |
concentration-response curves for dopamine on [3h]ach release were inhibited by haloperidol, sulpiride and domperidone but not by prazosin, yohimbine, propranolol and ketanserin. |
1985-10-09 |
2023-08-11 |
Not clear |
| N T Maidment, C A Marsde. In vivo voltammetric and behavioural evidence for somatodendritic autoreceptor control of mesolimbic dopamine neurones. Brain research. vol 338. issue 2. 1985-10-01. PMID:2992688. |
somatodendritic autoreceptor control of mesolimbic dopamine neurones was assessed using in vivo differential pulse voltammetry to monitor dopamine metabolism in the nucleus accumbens following infusion of haloperidol or dopamine into the ipsilateral ventral tegmental area (vta) of chloral hydrate anaesthetized rats. |
1985-10-01 |
2023-08-11 |
rat |
| N T Maidment, C A Marsde. In vivo voltammetric and behavioural evidence for somatodendritic autoreceptor control of mesolimbic dopamine neurones. Brain research. vol 338. issue 2. 1985-10-01. PMID:2992688. |
haloperidol (2.5 micrograms/0.5 microliters) produced an increase in dihydroxyphenylacetic acid (dopac) levels (45%) whilst dopamine produced a transient decrease (38%). |
1985-10-01 |
2023-08-11 |
rat |
| N M Rupniak, M D Hall, E Kelly, S Fleminger, G Kilpatrick, P Jenner, C D Marsde. Mesolimbic dopamine function is not altered during continuous chronic treatment of rats with typical or atypical neuroleptic drugs. Journal of neural transmission. vol 62. issue 3-4. 1985-09-27. PMID:2863324. |
after 20 months of continuous drug treatment, focal bilateral application of dopamine (12.5 or 25 micrograms) into the nucleus accumbens caused equivalent increases in locomotor activity in control rats and in animals receiving haloperidol, sulpiride or clozapine. |
1985-09-27 |
2023-08-11 |
rat |
| N M Rupniak, M D Hall, E Kelly, S Fleminger, G Kilpatrick, P Jenner, C D Marsde. Mesolimbic dopamine function is not altered during continuous chronic treatment of rats with typical or atypical neuroleptic drugs. Journal of neural transmission. vol 62. issue 3-4. 1985-09-27. PMID:2863324. |
these findings suggest that dopamine receptor blockade is not maintained in the mesolimbic area following chronic treatment with haloperidol, sulpiride or clozapine, and indicate that, under these conditions, clozapine and sulpiride may not act selectively on mesolimbic dopamine receptors. |
1985-09-27 |
2023-08-11 |
rat |
| G Mereu, M Collu, E Ongini, G Biggio, G L Gess. SCH 23390, a selective dopamine D1 antagonist, activates dopamine neurons but fails to prevent their inhibition by apomorphine. European journal of pharmacology. vol 111. issue 3. 1985-09-16. PMID:3894035. |
sch 23390, a rather selective d1 receptor blocker, activates the firing rate of dopamine (da) neurons in the substantia nigra (sn-da neurons) in rats, similarly to haloperidol (a d1-d2 receptor antagonist) and sulpiride (a selective d2 receptor blocker). |
1985-09-16 |
2023-08-11 |
rat |
| S Koyama, M Sasaki, T Setoyama, K Takahashi, K Togashi, K Suzuki, N Kakki, M Ima. Dopaminergic modulation of the renal effect of arginine-vasopressin in water-loaded rats. Japanese journal of pharmacology. vol 38. issue 1. 1985-09-11. PMID:4021228. |
in order to confirm whether dopamine inhibits the antidiuretic action of vasopressin in mammalian kidney, we examined interactions among arginine vasopressin (avp), dopamine and haloperidol in water-loaded ethanol anesthetized rats. |
1985-09-11 |
2023-08-11 |
rat |
| S Koyama, M Sasaki, T Setoyama, K Takahashi, K Togashi, K Suzuki, N Kakki, M Ima. Dopaminergic modulation of the renal effect of arginine-vasopressin in water-loaded rats. Japanese journal of pharmacology. vol 38. issue 1. 1985-09-11. PMID:4021228. |
the effect of 1.1 micrograms/100 g body weight dopamine in inhibiting the action of avp was completely reversed by haloperidol at 2.3 micrograms/100 g body weight. |
1985-09-11 |
2023-08-11 |
rat |
| S Koyama, M Sasaki, T Setoyama, K Takahashi, K Togashi, K Suzuki, N Kakki, M Ima. Dopaminergic modulation of the renal effect of arginine-vasopressin in water-loaded rats. Japanese journal of pharmacology. vol 38. issue 1. 1985-09-11. PMID:4021228. |
single administration of dopamine or haloperidol was without effect on urine flow. |
1985-09-11 |
2023-08-11 |
rat |
| J E Morley, A S Levine, J Kneip, M Grace, H Zeugner, G T Shearma. The kappa opioid receptor and food intake. European journal of pharmacology. vol 112. issue 1. 1985-08-27. PMID:2990965. |
low doses of the dopamine antagonist, haloperidol, enhance the bremazocine effect and higher doses inhibit it. |
1985-08-27 |
2023-08-11 |
Not clear |
| b' P Sikiri\\xc4\\x87, J Geber, E Suchanek, D Ivanovi\\xc4\\x87, V Gjuris, J Aleksi\\xc4\\x87, P Rei\\xc4\\x87, A Marovi\\xc4\\x8. The role of dopamine in the formation of gastric ulcers in rats. European journal of pharmacology. vol 112. issue 1. 1985-08-27. PMID:4018137.' |
a single dose of the dopamine antagonists haloperidol, sulpiride or domperidone potentiated the ulcerogenic effect by extending the length of stomach ulcerations. |
1985-08-27 |
2023-08-11 |
rat |
| D G Kirch, M R Palmer, M Egan, R Freedma. Electrophysiological interactions between haloperidol and reduced haloperidol, and dopamine, norepinephrine and phencyclidine in rat brain. Neuropharmacology. vol 24. issue 5. 1985-08-26. PMID:2862598. |
electrophysiological interactions between haloperidol and reduced haloperidol, and dopamine, norepinephrine and phencyclidine in rat brain. |
1985-08-26 |
2023-08-11 |
rat |
| A J Giannini, C Nageotte, R H Loiselle, D A Malone, W A Pric. Comparison of chlorpromazine, haloperidol and pimozide in the treatment of phencyclidine psychosis: DA-2 receptor specificity. Journal of toxicology. Clinical toxicology. vol 22. issue 6. 1985-08-19. PMID:6535849. |
these included chlorpromazine, a da-1 and da-2 dopamine antagonist with noradrenergic effects; haloperidol, a predominantly da-2 antagonist with noradrenergic effects; and pimozide a predominantly da-2 antagonist with no noradrenergic activity. |
1985-08-19 |
2023-08-12 |
Not clear |
| E Kelly, P Jenner, C D Marsde. The effects of dopamine and dopamine agonists on the release of 3H-GABA and 3H-5HT from rat nigral slices. Biochemical pharmacology. vol 34. issue 15. 1985-08-16. PMID:3925957. |
apomorphine (100 microm) and dopamine (100 microm) enhanced the spontaneous release of 3h-5ht but the effect of dopamine was not reversed by haloperidol (1 microm). |
1985-08-16 |
2023-08-11 |
rat |
| E Kelly, P Jenner, C D Marsde. The effects of dopamine and dopamine agonists on the release of 3H-GABA and 3H-5HT from rat nigral slices. Biochemical pharmacology. vol 34. issue 15. 1985-08-16. PMID:3925957. |
both apomorphine (100 microm) and dopamine (100 microm) enhanced the kcl-evoked release of 3h-5ht but these effects were not reversed by haloperidol (1 microm). |
1985-08-16 |
2023-08-11 |
rat |