| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Ellenbroek, M Schwarz, K H Sontag, R Jaspers, A Cool. Muscular rigidity and delineation of a dopamine-specific neostriatal subregion: tonic EMG activity in rats. Brain research. vol 345. issue 1. 1986-01-23. PMID:2998546. |
in order to investigate the role of neostriatal dopamine receptors in muscular rigidity we have studied catalepsy and spontaneous muscle tone in rats receiving haloperidol injections into various parts of the neostriatum. |
1986-01-23 |
2023-08-11 |
rat |
| D L Toan, W Schult. Responses of rat pallidum cells to cortex stimulation and effects of altered dopaminergic activity. Neuroscience. vol 15. issue 3. 1986-01-22. PMID:2866467. |
the dopaminergic influences on this corticopallidal impulse transmission were assessed by the systemic administration of the dopamine receptor-blocking neuroleptics, haloperidol and fluphenazine, as well as by conditioning electrical stimulation of the substantia nigra. |
1986-01-22 |
2023-08-11 |
rat |
| E L Shchelkunov, O G Kenunen, I B Voronov, A L Zimin, R A Kharitono. [Features of the temporal structure of the respiratory cycle in the Tourette syndrome as a possible reflection of intensified dopaminergic processes]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). vol 85. issue 10. 1986-01-22. PMID:3000115. |
the effect of dopamine blockers (chlorpromazine and haloperidol) and the dopaminomimetic piribedil on the structure of the breathing cycle was studied under conditions of the clinical employment of the drugs. |
1986-01-22 |
2023-08-11 |
Not clear |
| B A McMille. Comparative chronic effects of buspirone or neuroleptics on rat brain dopaminergic neurotransmission. Journal of neural transmission. vol 64. issue 1. 1986-01-17. PMID:2866230. |
when continuously infused into rats at 1.0 mg/kg/day s.c. for 2 weeks there was a small diminution of striatal dopamine metabolism response to acute injection of buspirone, but haloperidol produced a normal increase in dopac concentrations. |
1986-01-17 |
2023-08-11 |
rat |
| G Di Chiara, A Imperat. Rapid tolerance to neuroleptic-induced stimulation of dopamine release in freely moving rats. The Journal of pharmacology and experimental therapeutics. vol 235. issue 2. 1985-12-20. PMID:2865354. |
the effect of repeated s.c. administration of various neuroleptics (haloperidol, sulpiride and cis-flupentixol) on the in vivo release and metabolism of dopamine (da) was studied in freely moving rats using trans striatal dialysis coupled to reverse-phase high-pressure liquid chromatography with electrochemical detection. |
1985-12-20 |
2023-08-11 |
rat |
| J Alberch, J Marsal, C Solson. Modulation of the endogenous acetylcholine release from rat striatal slices. Brain research. vol 346. issue 2. 1985-12-20. PMID:2996707. |
the effect of dopamine antagonists, haloperidol and sulpiride, has been studied, and haloperidol was a better antagonist than sulpiride to the dopamine effect. |
1985-12-20 |
2023-08-11 |
rat |
| J Alberch, J Marsal, C Solson. Modulation of the endogenous acetylcholine release from rat striatal slices. Brain research. vol 346. issue 2. 1985-12-20. PMID:2996707. |
haloperidol elicited an acetylcholine release from striatal slices at 0.1 nm, probably by removing endogenous dopamine from dopaminergic receptors. |
1985-12-20 |
2023-08-11 |
rat |
| M Oka, T Karasawa, Y Ochi, K Asano, Y Terauchi, T Kadokaw. Differential effects of haloperidol decanoate, a long-acting neuroleptic, in behavioral and biochemical tests. Archives internationales de pharmacodynamie et de therapie. vol 277. issue 2. 1985-12-18. PMID:4062440. |
haloperidol decanoate itself was about 40 times less potent than haloperidol in inhibiting 3h-spiperone binding to rat striatum in vitro and its direct application into the cerebral ventricle of mice showed no effect on brain concentrations of dopamine metabolites, homovanillic acid (hva) and 3,4-dihydroxyphenylacetic acid (dopac). |
1985-12-18 |
2023-08-11 |
mouse |
| W F Nolan, D F Donnelly, E J Smith, R E Dutto. Haloperidol-induced suppression of carotid chemoreception in vitro. Journal of applied physiology (Bethesda, Md. : 1985). vol 59. issue 3. 1985-12-10. PMID:4055570. |
effects of antagonism of endogenous dopamine with haloperidol on single-unit frequency, interspike interval distribution, and interval serial dependency of the cat sinus nerve were tested using an in vitro carotid body-sinus nerve superfusion technique. |
1985-12-10 |
2023-08-11 |
cat |
| Y Ohno, M Sasa, S Takaor. Dopamine D-2 receptor-mediated excitation of caudate nucleus neurons from the substantia nigra. Life sciences. vol 37. issue 16. 1985-11-21. PMID:3900614. |
iontophoretic application of haloperidol and domperidone (dopamine d-2 receptor antagonist) produced dose-dependent inhibition of spikes elicited by sn stimulation in 25 of 42 and 50 of 82 cn neurons, respectively, however, no alterations of spikes elicited by mc stimulation occurred in any 11 neurons tested. |
1985-11-21 |
2023-08-11 |
Not clear |
| L J Rya. Catecholamine regulation of neocortical spindling in DBA/2 mice. Behavioural brain research. vol 16. issue 2-3. 1985-11-20. PMID:2994688. |
powerfully promoted bse occurrence and increased bse duration in freely-moving and midpontine-transected mice, whereas the dopamine antagonist haloperidol (2.0 mg/kg, i.p.) |
1985-11-20 |
2023-08-11 |
mouse |
| L J Rya. Catecholamine regulation of neocortical spindling in DBA/2 mice. Behavioural brain research. vol 16. issue 2-3. 1985-11-20. PMID:2994688. |
the convulsant drug pentylenetetrazol, which is known to promote bse occurrence at subconvulsant doses in dba/2 mice, may activate bses, in part, by activating dopamine neurons: 2.0 mg/kg haloperidol, i.p., partially blocked the facilitation of bses by 20 mg/kg pentylenetetrazol, i.p., in midpontine dba/2 mice. |
1985-11-20 |
2023-08-11 |
mouse |
| N Satake, S Ueda, S Shibat. Dopamine-induced potentiation of the contractile response to arachidonic acid in guinea-pig aorta. General pharmacology. vol 16. issue 4. 1985-11-19. PMID:3930345. |
the potentiation by dopamine was completely abolished by nordihydroguaiaretic acid, but not by indomethacin, aspirin, corticosterone, haloperidol, sk & f 83566, propranolol, pgi2 or imidazole. |
1985-11-19 |
2023-08-11 |
Not clear |
| A Campbell, R J Baldessarini, M H Teicher, N S Kul. Prolonged antidopaminergic actions of single doses of butyrophenones in the rat. Psychopharmacology. vol 87. issue 2. 1985-11-19. PMID:3931140. |
rats were treated once with doses of haloperidol or of droperidol below and above the acute id50 vs the dopamine agonist apomorphine; they were later challenged with an acute dose of apomorphine (0.3 mg/kg, sc) and rated for stereotyped behavioral responses. |
1985-11-19 |
2023-08-11 |
human |
| E Mignot, D Laud. Study of dopamine turnover by monitoring the decline of dopamine metabolites in rat CSF after alpha-methyl-p-tyrosine. Journal of neurochemistry. vol 45. issue 5. 1985-11-18. PMID:2864397. |
haloperidol pretreatment accelerated this decay, confirming the increase in brain dopamine turnover induced by neuroleptics. |
1985-11-18 |
2023-08-11 |
rat |
| A A Neduva, A M Zharkovskiĭ, O A Matvienko, A V Beliako. [Adaptation to neuroleptic preparations and several ways of combatting it (experimental study)]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). vol 85. issue 8. 1985-11-18. PMID:4050238. |
change in the function of dopamine receptors (zigzag administration of haloperidol or administration of the drug simultaneously with apomorphine) was found to restore the cataleptogenic properties of the neuroleptic. |
1985-11-18 |
2023-08-11 |
mouse |
| R G MacKenzie, M J Zigmon. Chronic neuroleptic treatment increases D-2 but not D-1 receptors in rat striatum. European journal of pharmacology. vol 113. issue 2. 1985-11-14. PMID:2864265. |
next, rats received haloperidol or fluphenazine for 54 days and striatal dopamine receptors were assayed 72 h later. |
1985-11-14 |
2023-08-11 |
rat |
| P Lafferty, D M Jackson, R Malo. Properties of a Ca2+ and Mg2+ stimulated ATPase in the rat caudate nucleus. Biochemical pharmacology. vol 34. issue 19. 1985-11-13. PMID:2932117. |
in vivo administration of dopamine (da) receptor antagonists (haloperidol, cis- and trans-flupenthixol, spiperone, chlorpromazine and trifluoperazine) and the agonist apomorphine neither inhibited nor stimulated atpase activity. |
1985-11-13 |
2023-08-11 |
rat |
| F Drago, U Scapagnin. Side effects of drugs stimulating prolactin secretion on the behavior of male rats. Archives internationales de pharmacodynamie et de therapie. vol 276. issue 2. 1985-11-13. PMID:4051646. |
dopamine antagonists, such as haloperidol and bromperidol, though causing hyperprolactinaemia, suppressed the acquisition of active avoidance behavior. |
1985-11-13 |
2023-08-11 |
rat |
| G R Breese, R A Muelle. SCH-23390 antagonism of a D-2 dopamine agonist depends upon catecholaminergic neurons. European journal of pharmacology. vol 113. issue 1. 1985-11-12. PMID:2864260. |
sch-23390, a selective d-1 dopamine antagonist, was found to antagonize the locomotor stimulation induced by ly-171555, an action similar to that for haloperidol in control animals. |
1985-11-12 |
2023-08-11 |
rat |