| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J P Herman, K Choulli, M Le Moa. Activation of striatal dopaminergic grafts by haloperidol. Brain research bulletin. vol 15. issue 6. 1986-03-21. PMID:3936594. |
the effect of haloperidol (0.5 mg/kg, 60 min) on striatal dopamine metabolism of intact rats and of rats bearing a dopaminergic graft implanted into the previously denervated striatum was investigated. |
1986-03-21 |
2023-08-11 |
rat |
| R W Fuller, S K Hemrick-Lueck. Mechanisms of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity to striatal dopamine neurons in mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 9. issue 5-6. 1986-03-18. PMID:3878976. |
in contrast, pretreatment with alpha-methyl-tyrosine, ro 4-1284 or haloperidol did not prevent the depletion of striatal dopamine by mptp. |
1986-03-18 |
2023-08-11 |
mouse |
| D D Rasmussen, J H Liu, P L Wolf, S S Ye. Gonadotropin-releasing hormone neurosecretion in the human hypothalamus: in vitro regulation by dopamine. The Journal of clinical endocrinology and metabolism. vol 62. issue 3. 1986-03-13. PMID:3511082. |
an in vitro perifusion system was used to investigate gnrh release from adult human hypothalami in response to dopamine (da) and the da receptor antagonist haloperidol (hal). |
1986-03-13 |
2023-08-11 |
human |
| S F Stewart, T A Pugsle. Increase of rat serum prolactin by adenosine analogs and their blockade by the methylxanthine aminophylline. Naunyn-Schmiedeberg's archives of pharmacology. vol 331. issue 2-3. 1986-03-03. PMID:3003588. |
haloperidol (a dopamine antagonist) and alpha-methyl-p-tyrosine (a catecholamine synthesis inhibitor) potentiated the r-pia-induced effects. |
1986-03-03 |
2023-08-11 |
rat |
| B Costall, R J Naylor, C C Ta. A central site of dopamine agonist action to modify gastric secretion in the rat. European journal of pharmacology. vol 117. issue 1. 1986-02-28. PMID:2867911. |
in gastric acid concentrations were antagonised by the dopamine antagonists metoclopramide, sulpiride or haloperidol and by the alpha 2-adrenoceptor antagonist yohimbine given systemically or i.c.v. |
1986-02-28 |
2023-08-11 |
rat |
| M D Tricklebank, C Forler, D N Middlemiss, J R Fozar. Subtypes of the 5-HT receptor mediating the behavioural responses to 5-methoxy-N,N-dimethyltryptamine in the rat. European journal of pharmacology. vol 117. issue 1. 1986-02-28. PMID:2935408. |
since forepaw treading induced by 5-meodmt was also blocked in intact rats by haloperidol, blockade of the behaviour by ketanserin may more accurately reflect antagonism at dopamine receptors than at 5-ht2 receptors. |
1986-02-28 |
2023-08-11 |
rat |
| M D Tricklebank, C Forler, D N Middlemiss, J R Fozar. Subtypes of the 5-HT receptor mediating the behavioural responses to 5-methoxy-N,N-dimethyltryptamine in the rat. European journal of pharmacology. vol 117. issue 1. 1986-02-28. PMID:2935408. |
with minimised contributions from other monoamine systems, neither forepaw treading nor the flat body posture were significantly altered by ketanserin, haloperidol or the beta 1- and beta 2-selective adrenoceptor antagonists, betaxolol and ici 118.551, making a key role for 5-ht2 receptors, dopamine receptors and beta-adrenoceptors unlikely. |
1986-02-28 |
2023-08-11 |
rat |
| F P Bymaster, L R Reid, C L Nichols, E C Kornfeld, D T Won. Elevation of acetylcholine levels in striatum of rat brain by LY163502, trans-(-)-5,5a,6,7,8,9a,10-octahydro-6-propylpyrimido less than 4,5-g greater than quinolin-2-amine dihydrochloride, a potent and stereospecific dopamine (D2) agonist. Life sciences. vol 38. issue 4. 1986-02-26. PMID:3753738. |
the elevation of ach levels by ly163502 is reversed by dopamine antagonists haloperidol, cis-flupenthixol and metoclopramide. |
1986-02-26 |
2023-08-11 |
rat |
| R Bluth, R Langnicke. Effects of haloperidol and low dose clozapine on the acetylcholine turnover rate in rat forebrain structures. Biomedica biochimica acta. vol 44. issue 10. 1986-02-20. PMID:4084256. |
it can be concluded that haloperidol increases the acetylcholine turnover in both striatum and mesolimbic areas by blocking dopamine receptors localized at cholinergic interneurons. |
1986-02-20 |
2023-08-11 |
rat |
| J Yana. Implications of changes in apomorphine-induced hypothermia after prenatal exposure to phenobarbital. Alcohol and drug research. vol 6. issue 1. 1986-02-19. PMID:4074471. |
in order to acquire further understanding of the alterations in apomorphine hypothermia, mainly in relation to dopamine (da) receptors, adult intact mice were exposed to haloperidol for 4 weeks (25 mg/kg milled food) in order to increase their da receptor number, and their hypothermic response to apomorphine was tested 4 days post withdrawal. |
1986-02-19 |
2023-08-11 |
mouse |
| C Missale, M Pizzi, M Memo, G B Picotti, M O Carruba, P F Span. Postsynaptic D1 and D2 dopamine receptors are present in rabbit renal and mesenteric arteries. Neuroscience letters. vol 61. issue 1-2. 1986-02-18. PMID:2867503. |
measuring adenylate cyclase activity as a biochemical index of dopamine (da) receptors, it was found that the selective d1 da receptor agonist, skf 82526, was able to stimulate the camp formation in rabbit renal and mesenteric arteries, an effect blocked by haloperidol and by sch 23390. |
1986-02-18 |
2023-08-11 |
rabbit |
| L Brown, B Lorenz, E Erdman. The inotropic effects of dopamine and its precursor levodopa on isolated human ventricular myocardium. Klinische Wochenschrift. vol 63. issue 21. 1986-02-17. PMID:4079278. |
this inotropic effect was reduced by the beta 1-selective antagonist, 1-practolol (1 x 10(-6) m); the beta 2-selective antagonist, ici 118,551 hcl (1 x 10(-6) m); the dopamine antagonist, haloperidol (3 x 10(-6) m); the neuronal uptake inhibitor, cocaine (3 x 10(-5) m), but not by the alpha 1-antagonist, prazosin (1 x 10(-7) m). |
1986-02-17 |
2023-08-11 |
human |
| K Yamaguchi, T Nabeshima, M Amano, S Yoshida, H Furukawa, T Kameyam. Phencyclidine-induced dopamine-dependent behaviors in chronic haloperidol-treated rats. Pharmacology, biochemistry, and behavior. vol 23. issue 5. 1986-02-13. PMID:4080767. |
this study was designed to assess whether phencyclidine (pcp) produces dopamine (da)-dependent behaviors such as licking, biting and gnawing at low doses after withdrawal from chronic haloperidol (hal) treatment in rats. |
1986-02-13 |
2023-08-11 |
rat |
| L M Leitner, M Roum. Effects of dopamine superfusion on the activity of rabbit carotid chemoreceptors in vitro. Neuroscience. vol 16. issue 2. 1986-02-07. PMID:2417159. |
dopamine antagonists, (+)-butaclamol and haloperidol did not affect the responses to dopamine and to hypoxia. |
1986-02-07 |
2023-08-11 |
rabbit |
| G Maxwell, S Crompton, C Smyt. The effect of dopamine upon oxidative metabolism of brown fat adipocytes. European journal of pharmacology. vol 116. issue 3. 1986-02-05. PMID:2416573. |
the dopamine response could be blocked by haloperidol, butaclamol, propranolol and by high concentrations of tolazoline. |
1986-02-05 |
2023-08-11 |
Not clear |
| W Wesemann, D Hoffman. Solubilized ketanserin binding sites from pig platelet membranes. Thrombosis research. vol 39. issue 6. 1986-01-29. PMID:2934860. |
binding to this site was not inhibited by the dopamine antagonist haloperidol which, however, displaced [3h]ketanserin bound to the low affinity site. |
1986-01-29 |
2023-08-11 |
Not clear |
| S Coyle, T C Napier, G R Brees. Ontogeny of tolerance to haloperidol: behavioral and biochemical measures. Brain research. vol 355. issue 1. 1986-01-28. PMID:4075104. |
subjects were sacrificed 70 min after the injection of the test dose of haloperidol or saline and the corpus striatum and olfactory tubercles were dissected for hplc determination of dopamine (da) and its metabolites, homovanillic acid (hva) and 3,4-dihydroxyphenylacetic acid (dopac). |
1986-01-28 |
2023-08-11 |
human |
| K Ishii, T Kat. Increase of dopamine turnover in bilateral striata after unilateral injection of haloperidol into substantia nigra of unrestrained rats. Brain research. vol 359. issue 1-2. 1986-01-24. PMID:3000522. |
increase of dopamine turnover in bilateral striata after unilateral injection of haloperidol into substantia nigra of unrestrained rats. |
1986-01-24 |
2023-08-11 |
rat |
| K Ishii, T Kat. Increase of dopamine turnover in bilateral striata after unilateral injection of haloperidol into substantia nigra of unrestrained rats. Brain research. vol 359. issue 1-2. 1986-01-24. PMID:3000522. |
in order to investigate self-regulation of dopamine (da) neurons, the effects of intranigrally administered haloperidol (hal), a da receptor antagonist, on nigrostriatal da systems were examined using differential pulse voltammetry with carbon fiber electrode. |
1986-01-24 |
2023-08-11 |
rat |
| S M Pellis, Y C Chen, R M Chesire, P Teitelbau. Head displacement and bracing in haloperidol-treated rats compared to rats with lateral hypothalamic damage. Physiology & behavior. vol 35. issue 5. 1986-01-24. PMID:3936074. |
in this report the bracing responses of two cataleptic preparations were compared: (1) intact rats given haloperidol, a dopamine antagonist, and (2) rats with large lesions of the lateral hypothalamus (lh). |
1986-01-24 |
2023-08-11 |
rat |