| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' P Sikiri\\xc4\\x87, J Geber, E Suchanek, D Ivanovi\\xc4\\x87, V Gjuris, J Aleksi\\xc4\\x87, P Rei\\xc4\\x87, A Marovi\\xc4\\x8. The role of dopamine in the formation of gastric ulcers in rats. European journal of pharmacology. vol 112. issue 1. 1985-08-27. PMID:4018137.' |
a single dose of the dopamine antagonists haloperidol, sulpiride or domperidone potentiated the ulcerogenic effect by extending the length of stomach ulcerations. |
1985-08-27 |
2023-08-11 |
rat |
| D G Kirch, M R Palmer, M Egan, R Freedma. Electrophysiological interactions between haloperidol and reduced haloperidol, and dopamine, norepinephrine and phencyclidine in rat brain. Neuropharmacology. vol 24. issue 5. 1985-08-26. PMID:2862598. |
electrophysiological interactions between haloperidol and reduced haloperidol, and dopamine, norepinephrine and phencyclidine in rat brain. |
1985-08-26 |
2023-08-11 |
rat |
| A J Giannini, C Nageotte, R H Loiselle, D A Malone, W A Pric. Comparison of chlorpromazine, haloperidol and pimozide in the treatment of phencyclidine psychosis: DA-2 receptor specificity. Journal of toxicology. Clinical toxicology. vol 22. issue 6. 1985-08-19. PMID:6535849. |
these included chlorpromazine, a da-1 and da-2 dopamine antagonist with noradrenergic effects; haloperidol, a predominantly da-2 antagonist with noradrenergic effects; and pimozide a predominantly da-2 antagonist with no noradrenergic activity. |
1985-08-19 |
2023-08-12 |
Not clear |
| E Kelly, P Jenner, C D Marsde. The effects of dopamine and dopamine agonists on the release of 3H-GABA and 3H-5HT from rat nigral slices. Biochemical pharmacology. vol 34. issue 15. 1985-08-16. PMID:3925957. |
apomorphine (100 microm) and dopamine (100 microm) enhanced the spontaneous release of 3h-5ht but the effect of dopamine was not reversed by haloperidol (1 microm). |
1985-08-16 |
2023-08-11 |
rat |
| E Kelly, P Jenner, C D Marsde. The effects of dopamine and dopamine agonists on the release of 3H-GABA and 3H-5HT from rat nigral slices. Biochemical pharmacology. vol 34. issue 15. 1985-08-16. PMID:3925957. |
both apomorphine (100 microm) and dopamine (100 microm) enhanced the kcl-evoked release of 3h-5ht but these effects were not reversed by haloperidol (1 microm). |
1985-08-16 |
2023-08-11 |
rat |
| N M Rupniak, M D Hall, S Mann, S Fleminger, G Kilpatrick, P Jenner, C D Marsde. Chronic treatment with clozapine, unlike haloperidol, does not induce changes in striatal D-2 receptor function in the rat. Biochemical pharmacology. vol 34. issue 15. 1985-08-16. PMID:4040370. |
comparison has been made of the effects on brain dopamine function of chronic administration of haloperidol or clozapine to rats for up to 12 months. |
1985-08-16 |
2023-08-11 |
rat |
| N M Rupniak, M D Hall, S Mann, S Fleminger, G Kilpatrick, P Jenner, C D Marsde. Chronic treatment with clozapine, unlike haloperidol, does not induce changes in striatal D-2 receptor function in the rat. Biochemical pharmacology. vol 34. issue 15. 1985-08-16. PMID:4040370. |
dopamine (50 microm)-stimulated adenylate cyclase activity was inhibited after 1 month's haloperidol treatment but normal thereafter. |
1985-08-16 |
2023-08-11 |
rat |
| N M Rupniak, M D Hall, S Mann, S Fleminger, G Kilpatrick, P Jenner, C D Marsde. Chronic treatment with clozapine, unlike haloperidol, does not induce changes in striatal D-2 receptor function in the rat. Biochemical pharmacology. vol 34. issue 15. 1985-08-16. PMID:4040370. |
these findings indicate that the chronic administration of the atypical neuroleptic clozapine does not produce changes in brain dopamine function which mirror those of the typical neuroleptic haloperidol. |
1985-08-16 |
2023-08-11 |
rat |
| M E Trulso. Activity of dopamine-containing substantia nigra neurons in freely moving cats. Neuroscience and biobehavioral reviews. vol 9. issue 2. 1985-08-13. PMID:3925396. |
the firing rates of these units were inhibited by dopamine agonists, including the direct-acting agonist, apomorphine, the dopamine precursor, l-dihydroxyphenylalanine, a dopamine releasing agent, d-amphetamine, and a dopamine reuptake blocker, bupropion, and were excited by a dopamine receptor blocker, haloperidol. |
1985-08-13 |
2023-08-11 |
rat |
| A G Dupont, R A Lefebvre, M G Bogaer. Inhibitory effects of apomorphine and pergolide on neurogenic vasoconstriction in the hindquarters of the rat. Naunyn-Schmiedeberg's archives of pharmacology. vol 329. issue 2. 1985-08-13. PMID:4010793. |
the inhibition by apomorphine and pergolide of the 4 hz stimulation-evoked pressor response was completely antagonized by local administration of the dopamine antagonist haloperidol (1 microgram . |
1985-08-13 |
2023-08-11 |
rat |
| D E Case. Behavioral effects of long-term neuroleptic treatment in Cebus monkeys. Psychopharmacology. Supplementum. vol 2. 1985-07-24. PMID:3858801. |
eight male cebus monkeys (15-18 years old) were tested with the dopamine agonists apomorphine, d-amphetamine, bromocriptine, and pergolide before, during, and after 3 months of treatment with haloperidol 0.25 mg/kg daily po. |
1985-07-24 |
2023-08-11 |
monkey |
| D E Case. Behavioral effects of long-term neuroleptic treatment in Cebus monkeys. Psychopharmacology. Supplementum. vol 2. 1985-07-24. PMID:3858801. |
initially haloperidol suppressed dopamine agonist-induced blms, but tolerance to the effect developed and was replaced by a potentiation of apomorphine-induced blms. |
1985-07-24 |
2023-08-11 |
monkey |
| F M Scalzo, L P Spea. Chronic haloperidol during development attenuates dopamine autoreceptor function in striatal and mesolimbic brain regions of young and older adult rats. Psychopharmacology. vol 85. issue 3. 1985-07-24. PMID:3923514. |
chronic haloperidol during development attenuates dopamine autoreceptor function in striatal and mesolimbic brain regions of young and older adult rats. |
1985-07-24 |
2023-08-11 |
rat |
| F M Scalzo, L P Spea. Chronic haloperidol during development attenuates dopamine autoreceptor function in striatal and mesolimbic brain regions of young and older adult rats. Psychopharmacology. vol 85. issue 3. 1985-07-24. PMID:3923514. |
the effects of chronic haloperidol administration during the prenatal and preweanling periods on dopamine autoreceptor function were examined in striatum, olfactory tubercles, and nucleus accumbens of young (2-3 month) and older (12-13 month) adult rats. |
1985-07-24 |
2023-08-11 |
rat |
| F M Scalzo, L P Spea. Chronic haloperidol during development attenuates dopamine autoreceptor function in striatal and mesolimbic brain regions of young and older adult rats. Psychopharmacology. vol 85. issue 3. 1985-07-24. PMID:3923514. |
in striatum of young and older adult rats that had been chronically treated with haloperidol early in life, as well as in the nucleus accumbens of older adults receiving early chronic haloperidol, gamma-butyrolactone (gbl) did not induce significant increases in dopamine levels. |
1985-07-24 |
2023-08-11 |
rat |
| F M Scalzo, L P Spea. Chronic haloperidol during development attenuates dopamine autoreceptor function in striatal and mesolimbic brain regions of young and older adult rats. Psychopharmacology. vol 85. issue 3. 1985-07-24. PMID:3923514. |
in olfactory tubercles of young adults that had received early chronic treatment with haloperidol, apomorphine pretreatment failed to reverse the observed gbl-induced increase in dopamine levels. |
1985-07-24 |
2023-08-11 |
rat |
| F M Scalzo, L P Spea. Chronic haloperidol during development attenuates dopamine autoreceptor function in striatal and mesolimbic brain regions of young and older adult rats. Psychopharmacology. vol 85. issue 3. 1985-07-24. PMID:3923514. |
thus, dopamine autoreceptor function appears to be attenuated in rats chronically treated with haloperidol during early development, in contrast to reports of autoreceptor supersensitivity following neuroleptic treatment in adulthood. |
1985-07-24 |
2023-08-11 |
rat |
| M O Maĭmets, E E Vasar, A M Nurk, L Kh Allikmet. [Role of serotonin and dopamine receptors in the mechanism of action of haloperidol and pirenperone]. Farmakologiia i toksikologiia. vol 48. issue 2. 1985-07-18. PMID:3996566. |
[role of serotonin and dopamine receptors in the mechanism of action of haloperidol and pirenperone]. |
1985-07-18 |
2023-08-11 |
Not clear |
| J S Hong, K Yoshikawa, T Kanamatsu, S L Sabo. Modulation of striatal enkephalinergic neurons by antipsychotic drugs. Federation proceedings. vol 44. issue 9. 1985-07-17. PMID:3838946. |
several lines of evidence, which showed that striatal levels of [met5]enkephalin (me) increase after the nigrostriatal dopaminergic pathway was interrupted by hemitransection or direct administration of 6-hydroxydopamine to the substantia nigra, or after repeated injections of either reserpine or haloperidol, suggest that dopamine (da) plays an important role in regulating the metabolism of me-containing neurons in the striatum. |
1985-07-17 |
2023-08-11 |
rat |
| S W Lamberts, T Verleun, R Oostero. Studies on the effects of catecholestrogens on prolactin secretion by cultured normal rat anterior pituitary cells. Endocrinology. vol 116. issue 6. 1985-07-10. PMID:2986958. |
the effect of the catecholestrogens on prl release by cultured pituitary cells was significant after 2 h and was still effective after 48 h. the mechanism of action of 2-ohe1 and 2-ohe2 probably does not involve dopamine receptors, as 50 nm haloperidol did not alter the prl release inhibitory effect of these substances. |
1985-07-10 |
2023-08-11 |
rat |