| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S K Rastogi, R B Rastogi, Y D Lapierre, R L Singha. Effect of baclofen and haloperidol on gamma-aminobutyric acid and dopamine systems in an animal model of tardive dyskinesia. General pharmacology. vol 13. issue 6. 1983-03-11. PMID:7152230. |
effect of baclofen and haloperidol on gamma-aminobutyric acid and dopamine systems in an animal model of tardive dyskinesia. |
1983-03-11 |
2023-08-12 |
Not clear |
| E B Nielsen, F J White, A M Holohean, P M Callahan, J B Appe. Behavioral and biochemical evidence for serotonergic actions of tetrahydro-beta-carbolines. Life sciences. vol 31. issue 22. 1983-03-11. PMID:7154844. |
the substitution of thbc for 0.1 mg/kg of lsd was analyzed further with antagonism tests in 16 animals and was attenuated by the serotonin (5-ht) antagonist bc-105 (pizotifen; 3 mg/kg) but not by the dopamine (da) antagonist haloperidol (0.1 mg/kg). |
1983-03-11 |
2023-08-12 |
rat |
| P D Hrdina, K Elson-Hartma. Effect of chronic treatment with amitriptyline and haloperidol on high affinity uptake of choline by synaptosomes from various regions of rat brain. Neuropharmacology. vol 21. issue 12. 1983-03-11. PMID:7155314. |
whereas blockade of dopamine receptors is likely to induce the observed alterations in high affinity choline uptake after administration of haloperidol, an antimuscarinic action may be involved in compensatory high affinity choline uptake increases after treatment with amitriptyline. |
1983-03-11 |
2023-08-12 |
rat |
| H Mizoguchi, V J Dzau, L G Siwek, A C Barge. Effect of intrarenal administration of dopamine on renin release in conscious dogs. The American journal of physiology. vol 244. issue 1. 1983-02-25. PMID:6336914. |
intrarenal infusion of sulpiride and haloperidol, dopamine antagonists, significantly inhibited dopamine-induced renin release and renal vasodilatation. |
1983-02-25 |
2023-08-12 |
Not clear |
| K Mueller, S Saboda, R Palmour, W L Nyha. Self-injurious behavior produced in rats by daily caffeine and continuous amphetamine. Pharmacology, biochemistry, and behavior. vol 17. issue 4. 1983-02-25. PMID:6891061. |
the dopamine antagonist haloperidol was only marginally effective in controlling sb produced by daily caffeine but the dopamine antagonist pimozide (which has a longer duration of action) prevented sb by amphetamine pellet rats. |
1983-02-25 |
2023-08-12 |
rat |
| W Peter, W Riede. Neurogenic non-adrenergic cutaneous vasodilatation elicited by hypothalamic thermal stimulation in dogs. Pflugers Archiv : European journal of physiology. vol 395. issue 2. 1983-02-25. PMID:7177778. |
dopamine and ergometrine produce cutaneous vasoconstriction which is antagonized or prevented by haloperidol. |
1983-02-25 |
2023-08-12 |
Not clear |
| A Lydén, B Larsson, N G Lindquis. Studies on the melanin affinity of haloperidol. Archives internationales de pharmacodynamie et de therapie. vol 259. issue 2. 1983-02-25. PMID:7181580. |
in vitro, haloperidol was found to be bound to beef-eye melanin and dopamine melanin (structurally similar to the melanin present in the pigmented nerve cells in the human substantia nigra). |
1983-02-25 |
2023-08-12 |
mouse |
| Y Iwayama, I Takayanag. Photoaffinity labelling of dopamine receptors in molluscan smooth muscle. The Journal of pharmacy and pharmacology. vol 34. issue 11. 1983-02-14. PMID:6129304. |
this inhibition of dopamine-induced responses continued for at least 2 h. the dose-response curve for dopamine was unaffected when the muscle was incubated with both dopamine (10(-4)m) and haloperidol (10(-4)m) for 25 min under the irradiation conditions (fig. |
1983-02-14 |
2023-08-12 |
Not clear |
| Y Iwayama, I Takayanag. Photoaffinity labelling of dopamine receptors in molluscan smooth muscle. The Journal of pharmacy and pharmacology. vol 34. issue 11. 1983-02-14. PMID:6129304. |
furthermore, when the muscle was incubated with dopamine (10(-4)m) or haloperidol (10(-4)m) for 25 min and washed with artificial sea water, the dose-response curve for dopamine was not influenced. |
1983-02-14 |
2023-08-12 |
Not clear |
| Y Iwayama, I Takayanag. Photoaffinity labelling of dopamine receptors in molluscan smooth muscle. The Journal of pharmacy and pharmacology. vol 34. issue 11. 1983-02-14. PMID:6129304. |
when promethazine (10(-4)m), an antihistamine drug found to have no antidopaminergic action in this muscle (yoshida et al 1981), was used instead of haloperidol (10(-4)m), the dose response curve for dopamine was shifted after irradiation (data not shown). |
1983-02-14 |
2023-08-12 |
Not clear |
| N Rosic, D H Overstree. Facilitation of active avoidance responding following chronic haloperidol treatment in rats. Psychopharmacology. vol 78. issue 2. 1983-02-14. PMID:6817369. |
these findings suggest that the increased dopamine receptors that have been reported following chronic haloperidol treatment may have functional relevance. |
1983-02-14 |
2023-08-12 |
rat |
| E Meller, K Bohmaker, H Rosengarten, A J Friedhof. Chronic haloperidol does not increase specific dopamine receptor binding in rat frontal cortex. Research communications in chemical pathology and pharmacology. vol 37. issue 3. 1983-02-14. PMID:7178646. |
chronic treatment of rats with haloperidol, 0.5 mg/kg for 3 weeks or 2.5 mg/kg for 5 weeks, did not alter the specific binding of [3h]spiroperidol to dopamine receptors in frontal cortex, whereas both treatments significantly increased binding to striatal dopamine receptors. |
1983-02-14 |
2023-08-12 |
rat |
| M C Tonon, P Leroux, M E Stoeckel, S Jegou, G Pelletier, H Vaudr. Catecholaminergic control of alpha-melanocyte-stimulating hormone (alpha MSH) release by frog neurointermediate lobe in vitro: evidence for direct stimulation of alpha MSH release by thyrotropin-releasing hormone. Endocrinology. vol 112. issue 1. 1983-01-27. PMID:6401174. |
since haloperidol and propranolol did not abolish the stimulation of alpha msh release induced by trh, it appeared that trh action was not mediated via an inhibition of dopamine release or via a stimulation of adrenergic nerve fibers. |
1983-01-27 |
2023-08-12 |
Not clear |
| I Cavero, R Massingham, F Lefèvere-Bor. Peripheral dopamine receptors, potential targets for a new class of antihypertensive agents. Part II: Sites and mechanisms of action of dopamine receptor agonists. Life sciences. vol 31. issue 11. 1983-01-19. PMID:6755118. |
this effect has been attributed to stimulation of dopamine receptors since it can be specifically antagonized by several dopamine receptor blocking agents (domperidone, haloperidol, pimozide, sulpiride). |
1983-01-19 |
2023-08-12 |
human |
| J A Nielsen, N J Duda, K E Moor. Tolerance develops to the haloperidol-induced increase in the efflux of dopamine metabolites from the brains of unanesthetized, freely-moving rats. Life sciences. vol 31. issue 14. 1983-01-07. PMID:6183554. |
complete tolerance developed to the haloperidol-induced increased efflux of dopamine metabolites by day 9, although a higher dose of haloperidol (2 mgf/kg) on day 15 was still capable of eliciting a modest increase in the efflux of dopac and hva. |
1983-01-07 |
2023-08-12 |
rat |
| M C de Mello, A L Ventura, R Paes de Carvalho, W L Klein, F G de Mell. Regulation of dopamine- and adenosine-dependent adenylate cyclase systems of chicken embryo retina cells in culture. Proceedings of the National Academy of Sciences of the United States of America. vol 79. issue 18. 1982-12-21. PMID:6291061. |
this spontaneous desensitization appeared to be caused by functional dopaminergic transmission because it could be blocked by the dopamine antagonist haloperidol. |
1982-12-21 |
2023-08-12 |
chicken |
| C T Douris. A pharmacological analysis of the hyperactivity syndrome induced by beta-phenylethylamine in the mouse. British journal of pharmacology. vol 77. issue 1. 1982-12-21. PMID:6982090. |
forward walking was inhibited by high doses of haloperidol or clozapine and potentiated by methergoline, mianserin or methysergide, suggesting that hyperactivity may also be mediated by dopamine but subject to 5-ht inhibition.7 abortive grooming was the dominant behavioural component observed after pea administration and was prevented by all of the antagonists tested which suggests that catecholamine and 5-ht mechanisms may be involved in the expression of this response.8 since pea is an endogenous compound in animals and man, and has been claimed to be present in abnormal amounts in some schizophrenics, pea-induced behavioural stimulation in mice (which includes the postulated hallucinogenic responses of abortive grooming and backward walking) may be a useful animal model of psychosis. |
1982-12-21 |
2023-08-12 |
mouse |
| R Schilkrut, C Haverbeck, E Duran, S Delgado, P Kohen, R Birkner, I Kat. [Standard and high doses of haloperidol. Clinical, pharmacokinetic and pharmacodynamic aspects]. Acta psiquiatrica y psicologica de America latina. vol 27. issue 4-5. 1982-12-21. PMID:7348089. |
in the range of dose studied, the use of higher than conventional doses of haloperidol results in an increased concentration in the cellular site of action and in a more complete blockade of central dopamine receptors. |
1982-12-21 |
2023-08-12 |
Not clear |
| N J Smatresk, S Lahir. Aortic body chemoreceptor responses to dopamine, haloperidol, and pargyline. Journal of applied physiology: respiratory, environmental and exercise physiology. vol 53. issue 3. 1982-12-18. PMID:7129979. |
aortic body chemoreceptor responses to dopamine, haloperidol, and pargyline. |
1982-12-18 |
2023-08-12 |
Not clear |
| N J Smatresk, S Lahir. Aortic body chemoreceptor responses to dopamine, haloperidol, and pargyline. Journal of applied physiology: respiratory, environmental and exercise physiology. vol 53. issue 3. 1982-12-18. PMID:7129979. |
aortic chemoreceptor activity, from single- or few-fiber afferent nerve preparations, was measured in response to dopamine and a dopaminergic blocker, haloperidol, in 18 anesthetized cats. |
1982-12-18 |
2023-08-12 |
Not clear |