| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Ishibashi, T Yamaj. Direct effects of thyrotropin-releasing hormone, cyproheptadine, and dopamine on adrenocorticotropin secretion from human corticotroph adenoma cells in vitro. The Journal of clinical investigation. vol 68. issue 4. 1981-12-21. PMID:6270192. |
dopamine (0.1 microm) lowered acth accumulation in the medium, which was blocked by the addition of haloperidol. |
1981-12-21 |
2023-08-12 |
human |
| M T Lin, J J Wu, A Chandra, B L Tsa. Activation of striatal dopamine receptors induces pain inhibition in rats. Journal of neural transmission. vol 51. issue 3-4. 1981-12-21. PMID:7288429. |
furthermore, the decreased pain sensitivity after the central administration of apomorphine was antagonized by pretreatment with haloperidol (a dopamine antagonist). |
1981-12-21 |
2023-08-12 |
rat |
| M T Lin, J J Wu, A Chandra, B L Tsa. Activation of striatal dopamine receptors induces pain inhibition in rats. Journal of neural transmission. vol 51. issue 3-4. 1981-12-21. PMID:7288429. |
on the other hand, lowering dopamine content in corpus striatum with electrolytic destruction of substantia nigra and 6-hydroxydopamine lesions to the substantia nigra, as well as direct injection of haloperidol into the lateral cerebral ventricle or caudate-putamen complex increased pain sensitivity. |
1981-12-21 |
2023-08-12 |
rat |
| G E Martin, C B Bacino, N L Pap. Action of selected serotonin antagonists on hyperthermia evoked by intracerebrally injected beta-endorphin. Peptides. vol 2. issue 2. 1981-12-15. PMID:6270636. |
since methergoline also interacts with the dopamine receptor, the effect of a dopamine antagonist, haloperidol, on the endorphin-evoked response was also examined. |
1981-12-15 |
2023-08-12 |
rat |
| A Hilditch, G M Dre. Characteristics of the dopamine receptors in the rabbit isolate splenic artery. European journal of pharmacology. vol 72. issue 4. 1981-11-22. PMID:7274328. |
fluphenazine, clozapine, trifluoperazine, haloperidol and spiroperidol also antagonised dopamine, but were relatively weak antagonists and a small part of their action was non-specific. |
1981-11-22 |
2023-08-12 |
dog |
| C Köhler, K Fuxe, S B Ros. Regional in vivo binding of [3H]N-propylnorapomorphine in the mouse brain. Evidence for labelling of central dopamine receptors. European journal of pharmacology. vol 72. issue 4. 1981-11-22. PMID:7274333. |
dopamine agonist (apomorphine, npa and bromocriptine) and antagonists (spiperone, haloperidol, (+) butaclamol and i-sulpiride) all caused dose-dependent prevention of [3h]npa binding. |
1981-11-22 |
2023-08-12 |
mouse |
| D M McDonald, R A Mitchel. The neural pathway involved in "efferent inhibition" of chemoreceptors in the cat carotid body. The Journal of comparative neurology. vol 201. issue 3. 1981-11-22. PMID:7276260. |
in operated cats as in control animals, "efferent inhibition" was abolished by haloperidol and dihydroergotamine, drugs that block the inhibitory action of dopamine. |
1981-11-22 |
2023-08-12 |
cat |
| F Teixeira, T R Maced. Influence of deaminated metabolites on the relaxing effect of dopamine on dog saphenous vein. The Journal of pharmacy and pharmacology. vol 33. issue 8. 1981-11-18. PMID:6115929. |
this effect is partially inhibited by propranolol and haloperidol suggesting that dopamine has two types of receptors in this vessel: beta- and dopaminergic receptors. |
1981-11-18 |
2023-08-12 |
dog |
| G M Asnis, E J Sachar, U Halbreich, L C Ostrow, R S Nathan, F S Halper. The prolactin-stimulating potency of reserpine in man. Psychiatry research. vol 5. issue 1. 1981-11-18. PMID:6944708. |
the fact that reserpine was found to be a potent releaser of prl--significantly greater than haloperidol--suggests a major role of storage pool dopamine in regulating prl secretion. |
1981-11-18 |
2023-08-12 |
Not clear |
| T C Hamilto. Involvement of the adrenal glands in the hypotensive response to bromocriptine in spontaneously hypertensive rats. British journal of pharmacology. vol 72. issue 3. 1981-10-29. PMID:6114765. |
2 in sh-rats the dose-related falls in blood pressure to bromocriptine, 3 to 30 mg/kg orally or intraperitoneally, were biphasic, an initial fall at 1 h being followed by some recovery at 2 h and a subsequent fall in blood pressure at 4 and 6 h. 3 the dopamine antagonists, metoclopramide, sulpiride, haloperidol and pimozide, had little or no effect on the hypotensive response to bromocriptine, 10 mg/kg orally, in sh-rats. |
1981-10-29 |
2023-08-12 |
rat |
| J S de Belleroche, H F Bradfor. Evidence for an inhibitory presynaptic component of neuroleptic drug action. British journal of pharmacology. vol 72. issue 3. 1981-10-29. PMID:6114766. |
1 the action of five neuroleptic drugs (haloperidol, cis-flupenthixol, chlorpromazine, fluphenazine and thioridazine) was studied on the synthesis and release of dopamine from rat striatal synaptosomes. |
1981-10-29 |
2023-08-12 |
rat |
| R H Falk, R D Desilva, B Low. Reduction in vulnerability to ventricular fibrillation by bromocriptine, a dopamine agonist. Cardiovascular research. vol 15. issue 3. 1981-10-29. PMID:7260985. |
pretreatment with the dopamine antagonist haloperidol abolished the effects of bromocriptine on vf threshold as did pretreatment with the peripheral dopamine antagonist, domperidone. |
1981-10-29 |
2023-08-12 |
Not clear |
| I S Login, I Nagy, R M MacLeo. Restoration of pituitary prolactin synthesis and release by the administration of morphine to rats bearing a transplanted prolactin-secreting tumor. Neuroendocrinology. vol 33. issue 2. 1981-10-25. PMID:7266770. |
morphine may reduce hypothalamic dopamine release, whereas haloperidol is a direct dopamine receptor antagonist in achieving these effects. |
1981-10-25 |
2023-08-12 |
rat |
| J M Jacobi, H M Lloy. Modulation by dopamine antagonists of DNA synthesis in the pituitary gland of the male rat. Neuroendocrinology. vol 33. issue 2. 1981-10-25. PMID:7266775. |
pituitary dna synthesis and serum and pituitary concentrations of prolactin were measured in male rats given the dopamine antagonist haloperidol or pimozide, and the dopamine agonist bromocriptine. |
1981-10-25 |
2023-08-12 |
rat |
| B K Ko. Levonantradol, a potent cannabinoid-related analgesic, antagonizes haloperidol-induced activation of striatal dopamine synthesis. European journal of pharmacology. vol 70. issue 2. 1981-10-14. PMID:6266845. |
levonantradol antagonized the compensatory acceleration of striatal dopamine synthesis induced by haloperidol. |
1981-10-14 |
2023-08-12 |
Not clear |
| L György, Z Orr, G Folly, M Dód. The influence of dopamine and dopaminergic agonists on the contractions of field stimulated rat vas deferens. Archives internationales de pharmacodynamie et de therapie. vol 250. issue 1. 1981-10-14. PMID:6268006. |
the inhibition due to dopamine and apomorphine was also counteracted by haloperidol and sulpiride, while that caused by bromocriptine and nomifensine only by sulpiride. |
1981-10-14 |
2023-08-12 |
rat |
| M J Kell. An analysis of the effects of apomorphine and haloperidol on the release of [3H]-dopamine and [3H]-noradrenaline from rabbit brain slices. Archives internationales de pharmacodynamie et de therapie. vol 250. issue 1. 1981-10-14. PMID:7271378. |
in low concentrations both compounds showed selectivity for dopaminergic receptor sites, apomorphine stimulating and haloperidol inhibiting pre-synaptic dopamine receptors. |
1981-10-14 |
2023-08-12 |
rabbit |
| G R Hanson, L Alphs, W Wolf, R Levine, W Lovenber. Haloperidol-induced reduction of nigral substance P-like immunoreactivity: a probe for the interactions between dopamine and substance P neuronal systems. The Journal of pharmacology and experimental therapeutics. vol 218. issue 2. 1981-09-25. PMID:6166743. |
protracted blockade of dopamine receptors by haloperidol has been shown to cause a reduction in nigral content of substance p-like immunoreactivity (spli). |
1981-09-25 |
2023-08-12 |
Not clear |
| G R Hanson, L Alphs, W Wolf, R Levine, W Lovenber. Haloperidol-induced reduction of nigral substance P-like immunoreactivity: a probe for the interactions between dopamine and substance P neuronal systems. The Journal of pharmacology and experimental therapeutics. vol 218. issue 2. 1981-09-25. PMID:6166743. |
data presented in this paper suggest that 1) blockade of dopamine postsynaptic receptors alters nigral spli levels associated with the substance p striatal-nigral loop, 2) destruction of the nigral-striatal dopaminergic pathway results in changes in nigral content of spli similar to that induced by haloperidol, 3) several weeks after nigral-striatal lesions, compensatory mechanisms mediate a return of nigral spli content to control levels and 4) substance p striatal-nigral circuits continue to respond to dopaminergic input after kainic acid lesions in the anterior striatum, whereas properly placed mechanical striatal-nigral lesions appear to be effective in preventing this interaction. |
1981-09-25 |
2023-08-12 |
Not clear |
| I C Kilpatrick, M S Star. Involvement of dopamine in circling responses to muscimol depends on intranigral site of injection. European journal of pharmacology. vol 69. issue 4. 1981-09-25. PMID:6265225. |
pretreatment with haloperidol (0.1 mg/kg) or pimozide (0.25 mg/kg), or by week-old 6-ohda lesions of the nigrostriatal dopamine (da) tract. |
1981-09-25 |
2023-08-12 |
rat |