| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Köhler, K Fuxe, S B Ros. Regional in vivo binding of [3H]N-propylnorapomorphine in the mouse brain. Evidence for labelling of central dopamine receptors. European journal of pharmacology. vol 72. issue 4. 1981-11-22. PMID:7274333. |
dopamine agonist (apomorphine, npa and bromocriptine) and antagonists (spiperone, haloperidol, (+) butaclamol and i-sulpiride) all caused dose-dependent prevention of [3h]npa binding. |
1981-11-22 |
2023-08-12 |
mouse |
| D M McDonald, R A Mitchel. The neural pathway involved in "efferent inhibition" of chemoreceptors in the cat carotid body. The Journal of comparative neurology. vol 201. issue 3. 1981-11-22. PMID:7276260. |
in operated cats as in control animals, "efferent inhibition" was abolished by haloperidol and dihydroergotamine, drugs that block the inhibitory action of dopamine. |
1981-11-22 |
2023-08-12 |
cat |
| F Teixeira, T R Maced. Influence of deaminated metabolites on the relaxing effect of dopamine on dog saphenous vein. The Journal of pharmacy and pharmacology. vol 33. issue 8. 1981-11-18. PMID:6115929. |
this effect is partially inhibited by propranolol and haloperidol suggesting that dopamine has two types of receptors in this vessel: beta- and dopaminergic receptors. |
1981-11-18 |
2023-08-12 |
dog |
| G M Asnis, E J Sachar, U Halbreich, L C Ostrow, R S Nathan, F S Halper. The prolactin-stimulating potency of reserpine in man. Psychiatry research. vol 5. issue 1. 1981-11-18. PMID:6944708. |
the fact that reserpine was found to be a potent releaser of prl--significantly greater than haloperidol--suggests a major role of storage pool dopamine in regulating prl secretion. |
1981-11-18 |
2023-08-12 |
Not clear |
| T C Hamilto. Involvement of the adrenal glands in the hypotensive response to bromocriptine in spontaneously hypertensive rats. British journal of pharmacology. vol 72. issue 3. 1981-10-29. PMID:6114765. |
2 in sh-rats the dose-related falls in blood pressure to bromocriptine, 3 to 30 mg/kg orally or intraperitoneally, were biphasic, an initial fall at 1 h being followed by some recovery at 2 h and a subsequent fall in blood pressure at 4 and 6 h. 3 the dopamine antagonists, metoclopramide, sulpiride, haloperidol and pimozide, had little or no effect on the hypotensive response to bromocriptine, 10 mg/kg orally, in sh-rats. |
1981-10-29 |
2023-08-12 |
rat |
| J S de Belleroche, H F Bradfor. Evidence for an inhibitory presynaptic component of neuroleptic drug action. British journal of pharmacology. vol 72. issue 3. 1981-10-29. PMID:6114766. |
1 the action of five neuroleptic drugs (haloperidol, cis-flupenthixol, chlorpromazine, fluphenazine and thioridazine) was studied on the synthesis and release of dopamine from rat striatal synaptosomes. |
1981-10-29 |
2023-08-12 |
rat |
| R H Falk, R D Desilva, B Low. Reduction in vulnerability to ventricular fibrillation by bromocriptine, a dopamine agonist. Cardiovascular research. vol 15. issue 3. 1981-10-29. PMID:7260985. |
pretreatment with the dopamine antagonist haloperidol abolished the effects of bromocriptine on vf threshold as did pretreatment with the peripheral dopamine antagonist, domperidone. |
1981-10-29 |
2023-08-12 |
Not clear |
| I S Login, I Nagy, R M MacLeo. Restoration of pituitary prolactin synthesis and release by the administration of morphine to rats bearing a transplanted prolactin-secreting tumor. Neuroendocrinology. vol 33. issue 2. 1981-10-25. PMID:7266770. |
morphine may reduce hypothalamic dopamine release, whereas haloperidol is a direct dopamine receptor antagonist in achieving these effects. |
1981-10-25 |
2023-08-12 |
rat |
| J M Jacobi, H M Lloy. Modulation by dopamine antagonists of DNA synthesis in the pituitary gland of the male rat. Neuroendocrinology. vol 33. issue 2. 1981-10-25. PMID:7266775. |
pituitary dna synthesis and serum and pituitary concentrations of prolactin were measured in male rats given the dopamine antagonist haloperidol or pimozide, and the dopamine agonist bromocriptine. |
1981-10-25 |
2023-08-12 |
rat |
| B K Ko. Levonantradol, a potent cannabinoid-related analgesic, antagonizes haloperidol-induced activation of striatal dopamine synthesis. European journal of pharmacology. vol 70. issue 2. 1981-10-14. PMID:6266845. |
levonantradol antagonized the compensatory acceleration of striatal dopamine synthesis induced by haloperidol. |
1981-10-14 |
2023-08-12 |
Not clear |
| L György, Z Orr, G Folly, M Dód. The influence of dopamine and dopaminergic agonists on the contractions of field stimulated rat vas deferens. Archives internationales de pharmacodynamie et de therapie. vol 250. issue 1. 1981-10-14. PMID:6268006. |
the inhibition due to dopamine and apomorphine was also counteracted by haloperidol and sulpiride, while that caused by bromocriptine and nomifensine only by sulpiride. |
1981-10-14 |
2023-08-12 |
rat |
| M J Kell. An analysis of the effects of apomorphine and haloperidol on the release of [3H]-dopamine and [3H]-noradrenaline from rabbit brain slices. Archives internationales de pharmacodynamie et de therapie. vol 250. issue 1. 1981-10-14. PMID:7271378. |
in low concentrations both compounds showed selectivity for dopaminergic receptor sites, apomorphine stimulating and haloperidol inhibiting pre-synaptic dopamine receptors. |
1981-10-14 |
2023-08-12 |
rabbit |
| G R Hanson, L Alphs, W Wolf, R Levine, W Lovenber. Haloperidol-induced reduction of nigral substance P-like immunoreactivity: a probe for the interactions between dopamine and substance P neuronal systems. The Journal of pharmacology and experimental therapeutics. vol 218. issue 2. 1981-09-25. PMID:6166743. |
protracted blockade of dopamine receptors by haloperidol has been shown to cause a reduction in nigral content of substance p-like immunoreactivity (spli). |
1981-09-25 |
2023-08-12 |
Not clear |
| G R Hanson, L Alphs, W Wolf, R Levine, W Lovenber. Haloperidol-induced reduction of nigral substance P-like immunoreactivity: a probe for the interactions between dopamine and substance P neuronal systems. The Journal of pharmacology and experimental therapeutics. vol 218. issue 2. 1981-09-25. PMID:6166743. |
data presented in this paper suggest that 1) blockade of dopamine postsynaptic receptors alters nigral spli levels associated with the substance p striatal-nigral loop, 2) destruction of the nigral-striatal dopaminergic pathway results in changes in nigral content of spli similar to that induced by haloperidol, 3) several weeks after nigral-striatal lesions, compensatory mechanisms mediate a return of nigral spli content to control levels and 4) substance p striatal-nigral circuits continue to respond to dopaminergic input after kainic acid lesions in the anterior striatum, whereas properly placed mechanical striatal-nigral lesions appear to be effective in preventing this interaction. |
1981-09-25 |
2023-08-12 |
Not clear |
| I C Kilpatrick, M S Star. Involvement of dopamine in circling responses to muscimol depends on intranigral site of injection. European journal of pharmacology. vol 69. issue 4. 1981-09-25. PMID:6265225. |
pretreatment with haloperidol (0.1 mg/kg) or pimozide (0.25 mg/kg), or by week-old 6-ohda lesions of the nigrostriatal dopamine (da) tract. |
1981-09-25 |
2023-08-12 |
rat |
| K Anderson, A Kuruvilla, N Uretsky, D D Mille. Synthesis and pharmacological evaluation of sulfonium analogues of dopamine: nonclassical dopamine agonists. Journal of medicinal chemistry. vol 24. issue 6. 1981-09-22. PMID:7252978. |
the effects of all three compounds on circling were inhibited by the dopamine antagonist haloperidol. |
1981-09-22 |
2023-08-12 |
rat |
| A A Megens, A R Cool. Presence of a particular subpopulation of dopamine receptors within the septal nuclei: a behavioural study on cats. European journal of pharmacology. vol 71. issue 2-3. 1981-09-15. PMID:6265235. |
the behavioural effects of intraseptal administration of dopaminergic drugs (apomorphine, haloperidol, (3,4-dihydroxy-phenylamino)-2-imidazoline (dpi), ergometrine and dopamine) and alpha-noradrenergic drugs (oxymetazoline, noradrenaline and phentolamine) were analysed in cats pretreated with morphine (5 mg/kg, i.p.). |
1981-09-15 |
2023-08-12 |
Not clear |
| J M Palacios, D L Niehoff, M J Kuha. [3H]Spiperone binding sites in brain: autoradiographic localization of multiple receptors. Brain research. vol 213. issue 2. 1981-09-15. PMID:7248759. |
differential drug sensitivity allowed the selective displacement of [3h]sp from dopamine receptors by adtn, from serotonin receptors by cinanserin, from both by haloperidol and from unique spiperone sites by unlabeled spiperone. |
1981-09-15 |
2023-08-12 |
rat |
| R Ovcharov, N Danche. [Interrelationship of the tranquilizers diazepam and lonetil with dopamine mediation in the central nervous system]. Eksperimentalna meditsina i morfologiia. vol 20. issue 2. 1981-09-15. PMID:7250025. |
in this analysis they used dopamine agonist apomorphine and dopamine antagonist haloperidol. |
1981-09-15 |
2023-08-12 |
rat |
| K S Kendler, G R Heninger, R H Rot. Brain contribution to the haloperidol-induced increase in plasma homovanillic acid. European journal of pharmacology. vol 71. issue 2-3. 1981-09-15. PMID:7250191. |
haloperidol increases the plasma concentration of the dopamine (da) metabolite homovanillic acid (hva). |
1981-09-15 |
2023-08-12 |
Not clear |