| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Wachtmeiste. Further studies of the chemical sensitivity of the oscillatory potentials of the electroretinogram (ERG). II. Glutamate-aspartate-and dopamine antagonists. Acta ophthalmologica. vol 59. issue 2. 1981-09-15. PMID:7257744. |
haloperidol, which antagonizes the effect of the inhibitory transmitter agent dopamine, differentially affected the ops. |
1981-09-15 |
2023-08-12 |
Not clear |
| R F Schlemmer, J M Davi. Evidence for dopamine mediation of submissive gestures in the stumptail macaque monkey. Pharmacology, biochemistry, and behavior. vol 14 Suppl 1. 1981-08-20. PMID:7243853. |
in addition, it appears that the significant increase in submissive gestures by monkeys treated with the hallucinogen 5-methoxy n,n-dimethyltryptamine is also mediated through dopamine systems since the preferential dopamine receptor blockers haloperidol and trifluoperazine antagonized this response while the serotonin antagonists cinanserin, methysergide, metergoline, and cyproheptadine all failed to antagonize or even potentiate this behavioral change. |
1981-08-20 |
2023-08-12 |
monkey |
| K Maeda, L A Frohma. Neurotensin release by rat hypothalamic fragments in vitro. Brain research. vol 210. issue 1-2. 1981-07-23. PMID:6261874. |
dopamine (10(-4)--10(-6) m) stimulated neurotensin release in a dose-dependent manner and this effect was blocked by the dopamine receptor antagonist, haloperidol. |
1981-07-23 |
2023-08-12 |
rat |
| J H Gordon, B I Diamon. Antagonism of dopamine supersensitivity by estrogen: neurochemical studies in an animal model of tardive dyskinesia. Biological psychiatry. vol 16. issue 4. 1981-07-23. PMID:7194695. |
the withdrawal from chronic haloperidol or estradiol benzoate (eb) treatment results in a behavioral supersensitivity to dopamine agonists in ovariectomized rats. |
1981-07-23 |
2023-08-12 |
rat |
| J H Gordon, B I Diamon. Antagonism of dopamine supersensitivity by estrogen: neurochemical studies in an animal model of tardive dyskinesia. Biological psychiatry. vol 16. issue 4. 1981-07-23. PMID:7194695. |
on the other hand, the administration of eb during the withdrawal from haloperidol or the continuous treatment with eb will attenuate or prevent the development of a supersensitivity to dopamine agonists. |
1981-07-23 |
2023-08-12 |
rat |
| J H Gordon, B I Diamon. Antagonism of dopamine supersensitivity by estrogen: neurochemical studies in an animal model of tardive dyskinesia. Biological psychiatry. vol 16. issue 4. 1981-07-23. PMID:7194695. |
the administration of eb during the withdrawal from chronic haloperidol treatment or the continuous administration of eb decreases or prevents the proliferation of dopamine binding sites in the striatum that normally orccur upon withdrawal of these two substances. |
1981-07-23 |
2023-08-12 |
rat |
| S Gentleman, M Parenti, J W Commissiong, N H Nef. Dopamine-activated adenylate cyclase of spinal cord: supersensitivity following transection of the cord. Brain research. vol 210. issue 1-2. 1981-07-23. PMID:7225811. |
the concentration of dopamine producing half-maximal activation is about 5 microm and the activation is blocked by haloperidol. |
1981-07-23 |
2023-08-12 |
rat |
| T Patterson, P H Venable. Bilateral skin conductance and the pupillary light-dark reflex: manipulation by chlorpromazine, haloperidol, scopolamine, and placebo. Psychopharmacology. vol 73. issue 1. 1981-07-20. PMID:6785791. |
blockade of dopamine with haloperidol produces an increase in amplitude and shortening of recovery time in the scor of normal subjects. |
1981-07-20 |
2023-08-12 |
human |
| F J White, J B Appe. A neuropharmacological analysis of the discriminative stimulus properties of fenfluramine. Psychopharmacology. vol 73. issue 2. 1981-07-20. PMID:6785800. |
since the indirect dopamine (da) agonist d-amphetamine failed to substitute and the da antagonist haloperidol failed to block the fenfluramine cue, a mediating role for da was not indicated. |
1981-07-20 |
2023-08-12 |
rat |
| C Sumners, G N Woodruff, J A Poa. Effects of specific dopamine lesions and dopamine receptor sensitivity on angiotensin II- and carbachol-induced thirst in rats. Psychopharmacology. vol 73. issue 2. 1981-07-20. PMID:6785812. |
chronic haloperidol treatment increased behavioural responses to the dopamine agonist apomorphine and significantly stimulated angiotensin-induced drinking without affecting response to carbachol. |
1981-07-20 |
2023-08-12 |
rat |
| L B Wallnau, G D Bordash, P Cors. Tonic immobility in domestic fowl: possible interaction of serotonergic and dopaminergic mechanisms. Pharmacology, biochemistry, and behavior. vol 14. issue 4. 1981-07-20. PMID:7195036. |
treatment with the dopamine (da) receptor blocker, haloperidol, enhanced tonic immobility (ti) duration. |
1981-07-20 |
2023-08-12 |
Not clear |
| G Langer, W Pühringe. Haloperidol and droperidol treatment in schizophrenics. Clinical application of the "prolactin-model". Acta psychiatrica Belgica. vol 80. issue 5. 1981-07-09. PMID:7234451. |
longitudinal studies are presented in four schizophrenic patients to investigate further the relationship between neuroleptic treatment (haloperidol or droperidol), plasma prolactin response, suppression of neuroleptic-induced prolactin elevation by dopamine infusion, and psychopathological change. |
1981-07-09 |
2023-08-12 |
Not clear |
| V S Fang, L R Shia. A serotonergic mechanism of the prolactin-stimulating action of metoclopramide. Endocrinology. vol 108. issue 5. 1981-06-25. PMID:6452260. |
pcpa did not enhance the prl-stimulating effect of haloperidol, a well established dopamine antagonist, l-alpha-methyl-p-tyrosine pretreatment in rats depleted hypothalamic dopamine without any change in serotonin and elevated basal prl, but failed to show an additive effect with metoclopramide's action on serum prl. |
1981-06-25 |
2023-08-12 |
rat |
| S Tufi. Changes of response to dopaminergic drugs in rats submitted to REM-sleep deprivation. Psychopharmacology. vol 72. issue 3. 1981-06-23. PMID:6111823. |
it has been claimed that 24 h after haloperidol a state of supersensitivity to dopamine agonists occurs in the brain; therefore, it is probable that rem deprivation could also act similarly. |
1981-06-23 |
2023-08-12 |
rat |
| R S Kamer, A R Turi, P R Solomon, L J Kapla. Increased mesolimbic dopamine binding following chronic haloperidol treatment. Psychopharmacology. vol 72. issue 3. 1981-06-23. PMID:6784143. |
increased mesolimbic dopamine binding following chronic haloperidol treatment. |
1981-06-23 |
2023-08-12 |
rat |
| J H Pazo, O R Tumilasci, J H Medin. Studies on the mechanisms of L-dopa-induced salivary secretion. European journal of pharmacology. vol 69. issue 3. 1981-06-13. PMID:7215428. |
pretreatment with haloperidol reduced the salivary secretion to l-dopa in normal animals (unoperated glands), while the response to dopamine was unaffected. |
1981-06-13 |
2023-08-12 |
rat |
| J Gripenberg, E Heinonen, S E Jansso. Uptake of radiocalcium by nerve endings isolated from rat brain: pharmacological studies. British journal of pharmacology. vol 71. issue 1. 1981-05-28. PMID:6258689. |
3 haloperidol at 1 x 10(-6) mol/l abolished the inhibitory effect of dopamine on the initial rapid phase of the high potassium-induced calcium uptake. |
1981-05-28 |
2023-08-12 |
rat |
| Y Satoh, H Satoh, F Hond. Dopamine receptor blocking activity of sulpiride in the canine exocrine pancreas. Japanese journal of pharmacology. vol 30. issue 5. 1981-05-28. PMID:7206375. |
the effect of dopamine was blocked by haloperidol, but not by atropine, cimetidine, phentolamine and propranolol. |
1981-05-28 |
2023-08-12 |
Not clear |
| Y Satoh, H Satoh, F Hond. Dopamine receptor blocking activity of sulpiride in the canine exocrine pancreas. Japanese journal of pharmacology. vol 30. issue 5. 1981-05-28. PMID:7206375. |
haloperidol had no effect on the effects of acetylcholine and histamine, but did inhibit the secretin-induced secretion, though the inhibitory effect was to a lesser extent than on the dopamine response. |
1981-05-28 |
2023-08-12 |
Not clear |
| G B Chesher, D M Jackso. Swim-induced grooming in mice is mediated by a dopaminergic substrate. Journal of neural transmission. vol 50. issue 1. 1981-05-26. PMID:6110702. |
cis-flupenthixol was less active in inhibiting grooming in animals chronically treated with haloperidol than in control animals, indicating the presence of supersensitive dopamine receptors. |
1981-05-26 |
2023-08-12 |
mouse |