| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Lappalainen, J Hietala, E Syvälaht. Differential tolerance to cataleptic effects of SCH 23390 and haloperidol after repeated administration. Psychopharmacology. vol 98. issue 4. 1989-09-29. PMID:2570432. |
differential tolerance to cataleptic effects of sch 23390 and haloperidol after repeated administration. |
1989-09-29 |
2023-08-11 |
rat |
| J Lappalainen, J Hietala, E Syvälaht. Differential tolerance to cataleptic effects of SCH 23390 and haloperidol after repeated administration. Psychopharmacology. vol 98. issue 4. 1989-09-29. PMID:2570432. |
the development of tolerance to the cataleptic effect of the selective d-1 antagonist sch 23390 (0.5 mg/kg/day sc or 0.1 mg/kg/day sc) and haloperidol (1 mg/kg/day sc) during repeated administration was investigated. |
1989-09-29 |
2023-08-11 |
rat |
| J Lappalainen, J Hietala, E Syvälaht. Differential tolerance to cataleptic effects of SCH 23390 and haloperidol after repeated administration. Psychopharmacology. vol 98. issue 4. 1989-09-29. PMID:2570432. |
sch 23390 induced a dose-related cataleptic effect of short duration, whereas the cataleptic effect of haloperidol appeared more slowly and lasted longer. |
1989-09-29 |
2023-08-11 |
rat |
| J Lappalainen, J Hietala, E Syvälaht. Differential tolerance to cataleptic effects of SCH 23390 and haloperidol after repeated administration. Psychopharmacology. vol 98. issue 4. 1989-09-29. PMID:2570432. |
these results suggest that different mechanisms are involved in the expression of cataleptic behaviour during chronic treatment with sch 23390 and classical antipsychotics, such as haloperidol. |
1989-09-29 |
2023-08-11 |
rat |
| P F Vonvoigtlander, R A Lewi. Evidence for the combined involvement of serotonergic and alpha 2 adrenergic mechanisms in the analgesic activity of tazadolene succinate. Drug design and delivery. vol 2. issue 2. 1989-09-28. PMID:2855569. |
however, yohimbine, sch 23390 and haloperidol, antagonists of alpha 2 adrenergic, d1 dopaminergic and d2 dopaminergic receptors respectively, did not block tazadolene, nor did the serotonin depletor, p-chlorophenylalanine. |
1989-09-28 |
2023-08-11 |
mouse |
| M Morelli, S Fenu, G Di Chiar. Substantia nigra as a site of origin of dopamine-dependent motor syndromes induced by stimulation of mu and delta opioid receptors. Brain research. vol 487. issue 1. 1989-08-31. PMID:2546645. |
sch 23390 and haloperidol, two antagonists of dopaminergic d1 and d2 receptors, respectively, blocked the effects of plo 17 and dpdpe. |
1989-08-31 |
2023-08-11 |
rat |
| J Hietal. Effects of DA-1- and DA-2-dopamine antagonists on apomorphine-induced inhibition of peripheral sympathetic neurotransmission. Journal of autonomic pharmacology. vol 8. issue 4. 1989-08-18. PMID:2855331. |
selective da-2 antagonists domperidone and (-)-sulpiride and combined da-2/da-1 antagonists haloperidol, fluphenazine and (+)-sulpiride were active in this model, whereas the da-1 antagonist sch 23390 and the alpha-2 adrenoceptor antagonist idazoxan (rx-781094) were inactive. |
1989-08-18 |
2023-08-11 |
rat |
| J Hietal. Effects of DA-1- and DA-2-dopamine antagonists on apomorphine-induced inhibition of peripheral sympathetic neurotransmission. Journal of autonomic pharmacology. vol 8. issue 4. 1989-08-18. PMID:2855331. |
the rank order of potency of the dopamine antagonists was domperidone greater than fluphenazine greater than or equal to (-)-sulpiride greater than or equal to haloperidol greater than (+)-sulpiride much greater than sch 23390. |
1989-08-18 |
2023-08-11 |
rat |
| R Dall'Olio, A Vaccheri, O Gandolfi, P Roncada, N Montanar. Neuroleptic-induced reduction of quipazine-elicited head-twitches in rats: possible involvement of striatal dopaminergic supersensitivity. Pharmacology, biochemistry, and behavior. vol 31. issue 4. 1989-08-01. PMID:2908069. |
the animals withdrawn from chlorpromazine, fluphenazine, haloperidol, metoclopramide and the d1 selective blocker sch 23390, showed enhanced hypermotility and/or stereotyped responses to apomorphine and reduced head-twitch response to quipazine. |
1989-08-01 |
2023-08-11 |
rat |
| V L Coffin, M B Latranyi, R E Chipki. Acute extrapyramidal syndrome in Cebus monkeys: development mediated by dopamine D2 but not D1 receptors. The Journal of pharmacology and experimental therapeutics. vol 249. issue 3. 1989-07-21. PMID:2567351. |
cebus monkeys were treated with either vehicle (n = 6), the specific d2 antagonist haloperidol (0.3 mg/kg p.o., n = 9) or the specific d1 antagonist sch 23390 (10.0 mg/kg p.o., n = 9) once a week for approximately 1 year and behavioral effects were observed and scored. |
1989-07-21 |
2023-08-11 |
monkey |
| P Popoli, M G Caporali, A Scotti de Caroli. The role of the purinergic system in the control of stereotypy: relationship to D-1/D-2 dopamine receptor activity. Pharmacology, biochemistry, and behavior. vol 32. issue 1. 1989-07-17. PMID:2525257. |
the stereotypy induced by caffeine + carbamazepine was not reduced by pretreatment with haloperidol (0.1 mg/kg) or sch 23390 (0.01 mg/kg). |
1989-07-17 |
2023-08-11 |
Not clear |
| P Popoli, M G Caporali, A Scotti de Caroli. The role of the purinergic system in the control of stereotypy: relationship to D-1/D-2 dopamine receptor activity. Pharmacology, biochemistry, and behavior. vol 32. issue 1. 1989-07-17. PMID:2525257. |
neither haloperidol (0.1 mg/kg) nor sch 23390 (0.01 mg/kg) were able to influence this eeg effect of caffeine. |
1989-07-17 |
2023-08-11 |
Not clear |
| J M Witkin, S R Goldberg, J L Kat. Lethal effects of cocaine are reduced by the dopamine-1 receptor antagonist SCH 23390 but not by haloperidol. Life sciences. vol 44. issue 18. 1989-06-14. PMID:2523996. |
lethal effects of cocaine are reduced by the dopamine-1 receptor antagonist sch 23390 but not by haloperidol. |
1989-06-14 |
2023-08-11 |
rat |
| M T Martin-Iverson, C T Douris. Role of dopamine D-1 and D-2 receptor subtypes in mediating dopamine agonist effects on food consumption in rats. Psychopharmacology. vol 96. issue 3. 1989-03-23. PMID:2906154. |
the increase in food pellet intake produced by phno was blocked by haloperidol (an antagonist relatively selective for the d-2 receptor at the dose used, 0.05 mg/kg) and sch 23390 (20 micrograms/kg, a d-1 receptor selective antagonist). |
1989-03-23 |
2023-08-11 |
rat |
| A D Crocker, D L Camero. Evidence for post-synaptic changes mediating increased behavioural sensitivity to dopamine receptor agonists in hypothyroid rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 12. issue 5. 1989-03-17. PMID:3065827. |
responses to the selective d1 antagonist, sch 23390, were decreased, but were increased to the d2 antagonist, haloperidol, in hypothyroid rats. |
1989-03-17 |
2023-08-11 |
rat |
| A Imperato, G Di Chiar. Effects of locally applied D-1 and D-2 receptor agonists and antagonists studied with brain dialysis. European journal of pharmacology. vol 156. issue 3. 1989-03-09. PMID:2905668. |
a specific d-1 agonist, the catechol benzazepine skf 38393, reduced da release and this effect was not modified by systemic or local administration of the d-1 antagonist, sch 23390, nor by the d-2 antagonist, haloperidol. |
1989-03-09 |
2023-08-11 |
rat |
| K Ichihara, T Nabeshima, T Kameyam. Effects of haloperidol, sulpiride and SCH 23390 on passive avoidance learning in mice. European journal of pharmacology. vol 151. issue 3. 1989-03-09. PMID:3063548. |
effects of haloperidol, sulpiride and sch 23390 on passive avoidance learning in mice. |
1989-03-09 |
2023-08-11 |
mouse |
| R E Chipki. Effects of D1 and D2 antagonists on basal and apomorphine decreased body temperature in mice and rats. Pharmacology, biochemistry, and behavior. vol 30. issue 3. 1989-02-23. PMID:2974995. |
in these experiments representative selective antagonists at d1 (sch 23390) and d2 (haloperidol) receptors were studied for their effects on basal and apomorphine decreased body temperature in mice and rats. |
1989-02-23 |
2023-08-11 |
mouse |
| M Vasse, P Protai. Increased grooming behaviour is induced by apomorphine in mice treated with discriminant benzamide derivatives. European journal of pharmacology. vol 156. issue 1. 1989-02-21. PMID:2905270. |
furthermore, only sch 23390, chlorpromazine and clozapine antagonized sk&f 38393 (1.87 mg/kg)-induced grooming behaviour, whereas the effects of flupentixol, thioridazine, metoclopramide, haloperidol and amisulpride in sk&f 38393-treated mice were parallel to those of control mice. |
1989-02-21 |
2023-08-11 |
mouse |
| C T Giambalv. Protein kinase C and dopamine release--II. Effect of dopamine acting drugs in vivo. Biochemical pharmacology. vol 37. issue 20. 1988-11-25. PMID:3056415. |
injections of fluphenazine, haloperidol, sch 23390 (d1 antagonist), sulpiride (d2 antagonist) or picrotoxin (gamma-aminobutyric acid antagonist which increases da release transneuronally) had the opposite effect of increasing particulate and decreasing soluble pkc activity. |
1988-11-25 |
2023-08-11 |
Not clear |