| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Maldonado, V Daugé, J Feger, B P Roque. Chronic blockade of D2 but not D1 dopamine receptors facilitates behavioural responses to endogenous enkephalins, protected by kelatorphan, administered in the accumbens in rats. Neuropharmacology. vol 29. issue 3. 1990-05-24. PMID:2157999. |
the drug sch 23390 did not modify the behavioural response to kelatorphan, whereas sulpiride and haloperidol induced an increase which was maximal in the third week after the beginning of treatment, a period corresponding to the appearance of the antipsychotic effect of the neuroleptics. |
1990-05-24 |
2023-08-11 |
rat |
| T Ljungber. Differential attenuation of water intake and water-rewarded operant responding by repeated administration of haloperidol and SCH 23390 in the rat. Pharmacology, biochemistry, and behavior. vol 35. issue 1. 1990-04-26. PMID:2179968. |
differential attenuation of water intake and water-rewarded operant responding by repeated administration of haloperidol and sch 23390 in the rat. |
1990-04-26 |
2023-08-11 |
rat |
| T Ljungber. Differential attenuation of water intake and water-rewarded operant responding by repeated administration of haloperidol and SCH 23390 in the rat. Pharmacology, biochemistry, and behavior. vol 35. issue 1. 1990-04-26. PMID:2179968. |
in the present study, effects of repeated administration of the da d-1 antagonist sch 23390 and the da d-2 antagonist haloperidol were investigated in the same experimental paradigm. |
1990-04-26 |
2023-08-11 |
rat |
| J Lappalainen, J Hietala, M Koulu, T Seppälä, B Sjöholm, E Syvälaht. Chronic treatment with SCH 23390 and haloperidol: effects on dopaminergic and serotonergic mechanisms in rat brain. The Journal of pharmacology and experimental therapeutics. vol 252. issue 2. 1990-04-16. PMID:2179533. |
chronic treatment with sch 23390 and haloperidol: effects on dopaminergic and serotonergic mechanisms in rat brain. |
1990-04-16 |
2023-08-11 |
rat |
| J Lappalainen, J Hietala, M Koulu, T Seppälä, B Sjöholm, E Syvälaht. Chronic treatment with SCH 23390 and haloperidol: effects on dopaminergic and serotonergic mechanisms in rat brain. The Journal of pharmacology and experimental therapeutics. vol 252. issue 2. 1990-04-16. PMID:2179533. |
effects of chronic administration (18 days) with sch 23390 (0.1 or 0.5 mg/kg/day s.c.) and haloperidol (1 mg/kg/day s.c.) on dopamine and serotonin synthesis and metabolism in discrete dopaminergic and serotonergic nuclei of rat brain were studied. |
1990-04-16 |
2023-08-11 |
rat |
| J Lappalainen, J Hietala, M Koulu, T Seppälä, B Sjöholm, E Syvälaht. Chronic treatment with SCH 23390 and haloperidol: effects on dopaminergic and serotonergic mechanisms in rat brain. The Journal of pharmacology and experimental therapeutics. vol 252. issue 2. 1990-04-16. PMID:2179533. |
chronic haloperidol, but not sch 23390, treatment induced a clear-cut increase in [3h]spiperone binding in caudate-putamen. |
1990-04-16 |
2023-08-11 |
rat |
| J Lappalainen, J Hietala, M Koulu, T Seppälä, B Sjöholm, E Syvälaht. Chronic treatment with SCH 23390 and haloperidol: effects on dopaminergic and serotonergic mechanisms in rat brain. The Journal of pharmacology and experimental therapeutics. vol 252. issue 2. 1990-04-16. PMID:2179533. |
interestingly, neither sch 23390 nor haloperidol treatments affected [3h]sch 23390 binding in caudate-putamen. |
1990-04-16 |
2023-08-11 |
rat |
| J Lappalainen, J Hietala, M Koulu, T Seppälä, B Sjöholm, E Syvälaht. Chronic treatment with SCH 23390 and haloperidol: effects on dopaminergic and serotonergic mechanisms in rat brain. The Journal of pharmacology and experimental therapeutics. vol 252. issue 2. 1990-04-16. PMID:2179533. |
sch 23390 and haloperidol had no significant effects on serotonin synthesis and metabolism in serotonergic and dopaminergic areas. |
1990-04-16 |
2023-08-11 |
rat |
| M A Linsema. Effects of dopaminergic agents on alcohol consumption by rats in a limited access paradigm. Psychopharmacology. vol 100. issue 2. 1990-03-27. PMID:1968278. |
ascending doses of amphetamine (0.1, 0.3 and 1.0 mg/kg), haloperidol (0.1, 0.3 and 1.0 mg/kg), skf 38393 (a d1 receptor agonist - 0.3, 1.0 and 3.0 mg/kg), quinpirole (ly 171555, a d2 receptor agonist - 0.03, 0.1 and 0.3 mg/kg), sch 23,390 (a d1 receptor blocker, 0.003, 0.01, 0.03 and 0.1 mg/kg) and spiperone (a d2 receptor blocker, 0.003, 0.01, 0.03 and 0.1 mg/kg) were administered ip to rats approximately 30 min prior to their 1-h per day access to alcohol. |
1990-03-27 |
2023-08-11 |
rat |
| Z L Rossetti, C P Silvia, D Krajnc, N H Neff, M Hadjiconstantino. Aromatic L-amino acid decarboxylase is modulated by D1 dopamine receptors in rat retina. Journal of neurochemistry. vol 54. issue 3. 1990-03-22. PMID:2137529. |
conversely, in the dark, enzyme activity can be enhanced by administering the selective d1 antagonist sch 23390 or haloperidol, but not the selective d2 antagonist (-)-sulpiride. |
1990-03-22 |
2023-08-11 |
rat |
| D J Heal, M R Prow, W R Bucket. Clonidine produces mydriasis in conscious mice by activating central alpha 2-adrenoceptors. European journal of pharmacology. vol 170. issue 1-2. 1990-03-06. PMID:2575524. |
of the dopamine antagonists, haloperidol, sch 23390 and brl 34778. |
1990-03-06 |
2023-08-11 |
mouse |
| J L Montastruc, G Gaillard, O Rascol, M A Tran, P Montastru. Effect of apomorphine on adrenal medullary catecholamine levels. Fundamental & clinical pharmacology. vol 3. issue 6. 1990-03-02. PMID:2575570. |
the action of apomorphine was suppressed by previous treatment with the non specific dopamine receptor antagonist, haloperidol (9 mg/kg ip), or the d2 antagonist domperidone (2 mg/kg ip), but not by the d1 antagonist sch 23390 (1 mg/kg ip). |
1990-03-02 |
2023-08-11 |
rat |
| T Ljungber. Effects of the dopamine D-1 antagonist SCH 23390 on water intake, water-rewarded operant responding and apomorphine-induced decrease of water intake in rats. Pharmacology, biochemistry, and behavior. vol 33. issue 3. 1989-12-29. PMID:2685829. |
in contrast to the da d-2 antagonist haloperidol, the attenuated operant lever-pressing induced by the da d-1 antagonist sch 23390 was not counteracted by the anticholinergic drug scopolamine. |
1989-12-29 |
2023-08-11 |
rat |
| G A Gudelsky, H Y Meltze. Activation of tuberoinfundibular dopamine neurons following the acute administration of atypical antipsychotics. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 2. issue 1. 1989-12-12. PMID:2572233. |
in contrast, the activity of these hypothalamic dopamine neurons was not acutely altered by the typical antipsychotics haloperidol, chlorpromazine, fluphenazine, and cis-flupentixol or by sch 23390. |
1989-12-12 |
2023-08-11 |
Not clear |
| N Waters, G Pettersson, A Carlsson, K Svensso. The putatively antipsychotic agent amperozide produces behavioural stimulation in the rat. A behavioural and biochemical characterization. Naunyn-Schmiedeberg's archives of pharmacology. vol 340. issue 2. 1989-12-12. PMID:2572972. |
in the behavioural paradigms it was not possible to antagonize the amperozide stimulation in reserpinized rats with the dopamine receptor blockers haloperidol, raclopride or r(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1 h-3-benzazepine, sch 23390. |
1989-12-12 |
2023-08-11 |
rat |
| P Montastruc, C Damase-Michel, J L Montastru. Apomorphine potentiates vagal bradycardia. European journal of pharmacology. vol 166. issue 3. 1989-11-27. PMID:2680522. |
pretreatment with the non-selective da antagonist, haloperidol, or the selective da2 antagonist, domperidone (but not the selective da1 antagonist, sch 23390), antagonized the effect of apomorphine. |
1989-11-27 |
2023-08-11 |
Not clear |
| D A Cory-Slechta, D V Widzowski, M C Newlan. Behavioral differentiation of the stimulus properties of a dopaminergic D1 agonist from a D2 agonist. The Journal of pharmacology and experimental therapeutics. vol 250. issue 3. 1989-10-17. PMID:2789282. |
the skf cue showed similar stimulus properties under both the skf/apo and skf/sal training conditions which were mediated by the d1 receptor: the skf response was blocked by the d1 antagonist sch 23390, but not by the d2 antagonist haloperidol. |
1989-10-17 |
2023-08-11 |
rat |
| D A Cory-Slechta, D V Widzowski, M C Newlan. Behavioral differentiation of the stimulus properties of a dopaminergic D1 agonist from a D2 agonist. The Journal of pharmacology and experimental therapeutics. vol 250. issue 3. 1989-10-17. PMID:2789282. |
in apo/sal-trained animals, the apo cue was d2 mediated; responding was blocked by haloperidol, but not by sch 23390 and apo responding generalized to the selective d2 agonist ly 171555 (quinpirole), but not to skf. |
1989-10-17 |
2023-08-11 |
rat |
| D A Cory-Slechta, D V Widzowski, M C Newlan. Behavioral differentiation of the stimulus properties of a dopaminergic D1 agonist from a D2 agonist. The Journal of pharmacology and experimental therapeutics. vol 250. issue 3. 1989-10-17. PMID:2789282. |
higher doses of apo appear to have d1 properties; doses above the training dose engendered skf responding in both the skf/sal and skf/apo groups, a response which could be blocked by the d1 antagonist sch 23390, but not by the d2 antagonist, haloperidol. |
1989-10-17 |
2023-08-11 |
rat |
| C F Smith, P B Rowlan. Dopamine receptors in the mouse vas deferens. Archives internationales de pharmacodynamie et de therapie. vol 299. 1989-10-05. PMID:2774764. |
domperidone, spiperone and haloperidol possess a very high affinity for the receptor, whereas the selective da1-antagonist sch 23390 has only low affinity. |
1989-10-05 |
2023-08-11 |
mouse |