| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Maj, Z Rogóz, G Skuz. Locomotor hyperactivity induced by MK-801 in rats. Polish journal of pharmacology and pharmacy. vol 43. issue 6. 1992-08-07. PMID:1687944. |
the mk-801-induced hyperactivity in rats was antagonized by haloperidol and, to a lesser degree, by sch 23390, a dopamine d-1 antagonist, and sulpiride, a dopamine d-2 antagonist. |
1992-08-07 |
2023-08-11 |
rat |
| M Diana, M Collu, A Mura, G L Gess. Haloperidol-induced vacuous chewing in rats: suppression by alpha-methyl-tyrosine. European journal of pharmacology. vol 211. issue 3. 1992-08-06. PMID:1352256. |
haloperidol-induced vc were inhibited by the s.c. administration of the specific dopamine d1, receptor antagonist, sch 23390 (0.025-0.100 mg/kg), in a dose-dependent manner, and were totally suppressed by an acute challenge with haloperidol (2 mg/kg i.p.) |
1992-08-06 |
2023-08-11 |
rat |
| A Verma, S K Kulkarn. Modulation of MK-801 response by dopaminergic agents in mice. Psychopharmacology. vol 107. issue 2-3. 1992-07-30. PMID:1352060. |
the response of mk-801 was blocked by pretreatment with haloperidol (0.5 mg/kg), molindone (2.5 mg/kg), clozapine (7.5 mg/kg) and sch 23390 (0.1 mg/kg). |
1992-07-30 |
2023-08-11 |
mouse |
| R J Care. Pavlovian conditioning of L-dopa induced movement. Psychopharmacology. vol 107. issue 2-3. 1992-07-30. PMID:1615121. |
additionally, drug tests with the combined dopaminergic receptor antagonists, sch 23390 (0.1 mg/kg) and haloperidol (0.5 mg/kg), at doses sufficient to block spontaneous behavior and l-dopa (20 mg/kg)-induced rotation, revealed that the conditioned contralateral rotation response, unlike l-dopa-induced contralateral rotation, is not affected by d1/d2 receptor blockade. |
1992-07-30 |
2023-08-11 |
rat |
| C E Tedford, G Crosby, L C Iorio, R E Chipki. Effect of SCH 39166, a novel dopamine D1 receptor antagonist, on [3H]acetylcholine release in rat striatal slices. European journal of pharmacology. vol 211. issue 2. 1992-07-28. PMID:1535318. |
electrically stimulated [3h]acetylcholine (ach) release from rat striatal slices was measured and comparisons were made between sch 39166, sch 23390, (-)-sulpiride, haloperidol or apomorphine on their effect on [3h]ach release. |
1992-07-28 |
2023-08-11 |
rat |
| M Yamauchi, Y Kobayashi, K Shimoura, K Hattori, A Nakas. Endothelium-dependent and -independent relaxation by dopamine in the rabbit pulmonary artery. Clinical and experimental pharmacology & physiology. vol 19. issue 6. 1992-07-21. PMID:1606742. |
in endothelium-intact strips, haloperidol, a da antagonist, and the da1 antagonists, fluphenazine and sch 23390 inhibited da-induced relaxations. |
1992-07-21 |
2023-08-11 |
rabbit |
| J G Pfaus, A G Phillip. Role of dopamine in anticipatory and consummatory aspects of sexual behavior in the male rat. Behavioral neuroscience. vol 105. issue 5. 1992-06-30. PMID:1840012. |
in experiment 1, systemic administration of haloperidol, pimozide, and the d1 antagonist sch 23390 reduced the number of anticipatory level changes (lc) displayed during a 5-min period before the introduction of a sexually receptive female, increased the mount and intromission latencies (ml and il), and decreased the number of intromissions before ejaculation (ni) and the total number of ejaculations (ne). |
1992-06-30 |
2023-08-11 |
rat |
| D E Case. Dopamine D1 (SCH 23390) and D2 (haloperidol) antagonists in drug-naive monkeys. Psychopharmacology. vol 107. issue 1. 1992-06-24. PMID:1534177. |
dopamine d1 (sch 23390) and d2 (haloperidol) antagonists in drug-naive monkeys. |
1992-06-24 |
2023-08-11 |
monkey |
| D E Case. Dopamine D1 (SCH 23390) and D2 (haloperidol) antagonists in drug-naive monkeys. Psychopharmacology. vol 107. issue 1. 1992-06-24. PMID:1534177. |
in this study, separate groups of neuroleptic drug-naive cebus monkeys were tested once weekly with intramuscularly administered sch 23390, a d1 antagonist, or haloperidol, a d2 antagonist, across a dose range of 0.01-0.25 mg/kg, and a saline control. |
1992-06-24 |
2023-08-11 |
monkey |
| D E Case. Dopamine D1 (SCH 23390) and D2 (haloperidol) antagonists in drug-naive monkeys. Psychopharmacology. vol 107. issue 1. 1992-06-24. PMID:1534177. |
sedation and locomotor activity were unchanged by sch 23390, but decreased with haloperidol. |
1992-06-24 |
2023-08-11 |
monkey |
| C E Tedford, V B Ruperto, A Barnet. Characterization of a rat liver glucuronosyltransferase that glucuronidates the selective D1 antagonist, SCH 23390, and other benzazepines. Drug metabolism and disposition: the biological fate of chemicals. vol 19. issue 6. 1992-04-29. PMID:1687024. |
substrate inhibition studies indicated that sch 23390, haloperidol, apomorphine, and alpha-naphthol demonstrated the highest affinity for the glucuronosyltransferase enzyme. |
1992-04-29 |
2023-08-11 |
rat |
| J H Abraini, C Tomei, J C Rostai. Role of dopamine receptors in the occurrence of the behavioral motor disturbances in rats exposed to high pressure. Pharmacology, biochemistry, and behavior. vol 39. issue 3. 1992-03-19. PMID:1686107. |
alternatively, hla was found to be dramatically antagonized by the use of da receptor antagonists (sch 23390, sulpiride, and haloperidol), while tremor and myoclonia only decreased in sch 23390 experiments. |
1992-03-19 |
2023-08-11 |
human |
| M Dragunow, G S Robertson, R L Faull, H A Robertson, K Janse. D2 dopamine receptor antagonists induce fos and related proteins in rat striatal neurons. Neuroscience. vol 37. issue 2. 1992-03-10. PMID:1966822. |
rats injected with haloperidol, which binds to both d2 dopamine and sigma receptors or the specific d2 dopamine receptor antagonist ym 09151-2, but not the specific d1 dopamine receptor antagonist sch 23390, showed induction of c-fos protein and c-fos-related antigens in striatal neurons. |
1992-03-10 |
2023-08-11 |
rat |
| J M Witkin, C W Schindler, S R Tella, S R Goldber. Interaction of haloperidol and SCH 23390 with cocaine and dopamine receptor subtype-selective agonists on schedule-controlled behavior of squirrel monkeys. Psychopharmacology. vol 104. issue 4. 1992-03-09. PMID:1838199. |
interaction of haloperidol and sch 23390 with cocaine and dopamine receptor subtype-selective agonists on schedule-controlled behavior of squirrel monkeys. |
1992-03-09 |
2023-08-11 |
monkey |
| D F Emerich, A B Norman, P R Sanber. Nicotine potentiates the behavioral effects of haloperidol. Psychopharmacology bulletin. vol 27. issue 3. 1992-03-02. PMID:1775613. |
the present experiments (1) compared the ability of nicotine to potentiate the catalepsy produced by haloperidol or the selective d1 dopamine receptor antagonist sch 23390 and (2) examined the effects of various doses of nicotine (0.1, 0.2, or 0.3 mg/kg) on haloperidol-induced (0.1, 0.2, or 0.4 mg/kg) catalepsy and locomotor hypoactivity. |
1992-03-02 |
2023-08-11 |
Not clear |
| D F Emerich, A B Norman, P R Sanber. Nicotine potentiates the behavioral effects of haloperidol. Psychopharmacology bulletin. vol 27. issue 3. 1992-03-02. PMID:1775613. |
in the first experiment, nicotine produced a five-fold increase in catalepsy following haloperidol but had no effect on the catalepsy produced by sch 23390. |
1992-03-02 |
2023-08-11 |
Not clear |
| K X Huang, J R Walter. D1 receptor stimulation inhibits dopamine cell activity after reserpine treatment but not after chronic SCH 23390: an effect blocked by N-methyl-D-aspartate antagonists. The Journal of pharmacology and experimental therapeutics. vol 260. issue 1. 1992-02-18. PMID:1530977. |
the skf 38393-induced inhibition was reversed by the d1 antagonist sch 23390, but not by the preferential d2 antagonist haloperidol. |
1992-02-18 |
2023-08-11 |
rat |
| M P DeNinno, R Schoenleber, R MacKenzie, D R Britton, K E Asin, C Briggs, J M Trugman, M Ackerman, L Artman, L Bednar. A68930: a potent agonist selective for the dopamine D1 receptor. European journal of pharmacology. vol 199. issue 2. 1991-12-30. PMID:1683288. |
when tested in rats bearing a unilateral 6-ohda lesion of the nigro-neostriatal neurons, a68930 elicits prolonged (greater than 20 h) contralateral turning that is antagonized by dopamine d1 receptor selective doses of sch 23390 but not by d2 receptor selective doses of haloperidol. |
1991-12-30 |
2023-08-11 |
rat |
| K Yoshino, S Kawagishi, M Iwamoto, N Aman. [A method for measuring the amount of retrogradely transported HRP in the rat masseteric motoneuron using Mesulam's HRP histochemical protocol and an image processing system. An investigation of the effect of dopamine receptor antagonists on the retrograde transport of HRP]. Nihon seirigaku zasshi. Journal of the Physiological Society of Japan. vol 53. issue 6. 1991-12-02. PMID:1941659. |
as a result, chlorpromazine, haloperidol, sch 23390, and sulpiride significantly enhanced retrograde transport of hrp as against domperidone which showed no significant change in the transport. |
1991-12-02 |
2023-08-11 |
rat |
| Z K Krowick. Dopamine receptor antagonists block the effect of Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) on the opiate form of footshock-induced analgesia. Neuropeptides. vol 19. issue 4. 1991-11-19. PMID:1681456. |
intraperitoneal pre-treatment with haloperidol (500 micrograms/kg), sch 23390 (150 micrograms/kg), or spiroperidol (150 micrograms/kg) potentiated the antinociceptive effect of the footshock and blocked the antagonistic action of tyr-mif-1 (200 micrograms/kg and 2.0 mg/kg). |
1991-11-19 |
2023-08-11 |
rat |