Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
G H Paalzo. Noradrenaline but not dopamine involved in NMDA receptor-mediated hyperalgesia induced by theophylline in awake rats. European journal of pharmacology. vol 252. issue 1. 1994-05-10. PMID:7908645. |
depletion of endogenous catecholamines with reserpine or alpha-methyl-dl-p-tyrosine and inhibition of noradrenaline synthesis with fla 63 reduced the theophylline-induced hyperalgesia, whereas blockade of dopamine d2 receptors by pimozide, haloperidol (2 mg/kg) or (-)-sulpiride, of dopamine d1 receptors by sch 23390, or of dopamine autoreceptors by a low dose of haloperidol (25 micrograms/kg), had no effect. |
1994-05-10 |
2023-08-12 |
rat |
P Bo, D Soragna, R Murelli, A Albergati, F Savold. [Role of the dopaminergic system in experimental models of epilepsy]. Bollettino della Societa italiana di biologia sperimentale. vol 69. issue 6. 1994-05-09. PMID:8148116. |
the aim of this work was to investigate whether the d-1 antagonist sch 23390 differs from haloperidol (d-2 antagonist) in models of experimental epilepsy induced by electrical stimulation of selected brain regions (hippocampus and amygdala), in rabbits. |
1994-05-09 |
2023-08-12 |
Not clear |
P Bo, D Soragna, R Murelli, A Albergati, F Savold. [Role of the dopaminergic system in experimental models of epilepsy]. Bollettino della Societa italiana di biologia sperimentale. vol 69. issue 6. 1994-05-09. PMID:8148116. |
haloperidol increased and sch 23390 significantly decreased the susceptibility to seizures in both models investigated. |
1994-05-09 |
2023-08-12 |
Not clear |
L Trevisan, L W Fitzgerald, N Brose, G P Gasic, S F Heinemann, R S Duman, E J Nestle. Chronic ingestion of ethanol up-regulates NMDAR1 receptor subunit immunoreactivity in rat hippocampus. Journal of neurochemistry. vol 62. issue 4. 1994-04-20. PMID:8133290. |
because ethanol can potentially influence many different neurotransmitter systems, we examined whether chronic treatment with several psychotropic drugs with different pharmacological profiles (cocaine, haloperidol, sch 23390, imipramine, and morphine) could mimic the effect of ethanol. |
1994-04-20 |
2023-08-12 |
rat |
P Laudrup, H Klitgaar. Metabotropic and ionotropic excitatory amino acid receptor agonists induce different behavioral effects in mice. European journal of pharmacology. vol 250. issue 1. 1994-04-04. PMID:7509749. |
neither mk-801 or nbqx (ed50 value > 100 nmol/min), nor the putative metabotropic receptor antagonist l-amino-3-phosphoro-propionic acid (l-ap3) (> 176 nmol/min); nor the dopamine receptor antagonists sch 23390 (> 74 nmol/min), metoclopramide (> 89 nmol/min) and haloperidol (> 27 nmol/min) antagonized 1s,3r-acpd-induced scratching (144 nmol/min). |
1994-04-04 |
2023-08-12 |
mouse |
R D Mayfield, P K Randall, W W Spirduso, R E Wilco. Selective D1 and D2 dopamine receptor antagonists produce differential effects on reaction time in the rat. Pharmacology, biochemistry, and behavior. vol 46. issue 4. 1994-03-15. PMID:8309952. |
the selective d1 antagonist sch 23390 (0, 70, and 100 micrograms/kg, ip) and the selective d2 antagonists spiperone (0, 1, and 10 micrograms/kg, ip) and haloperidol (0, 10, and 100 micrograms/kg, ip) were studied for their effects on successful avoidance and response latency. |
1994-03-15 |
2023-08-12 |
rat |
R D Mayfield, P K Randall, W W Spirduso, R E Wilco. Selective D1 and D2 dopamine receptor antagonists produce differential effects on reaction time in the rat. Pharmacology, biochemistry, and behavior. vol 46. issue 4. 1994-03-15. PMID:8309952. |
in contrast to the dose-related increase in response latencies produced by sch 23990, 1 microgram/kg spiperone and 10 micrograms/kg haloperidol significantly decreased the latencies of successful responses. |
1994-03-15 |
2023-08-12 |
rat |
S B Schwarzkopf, J P Bruno, T Mitr. Effects of haloperidol and SCH 23390 on acoustic startle and prepulse inhibition under basal and stimulated conditions. Progress in neuro-psychopharmacology & biological psychiatry. vol 17. issue 6. 1994-02-08. PMID:8278596. |
effects of haloperidol and sch 23390 on acoustic startle and prepulse inhibition under basal and stimulated conditions. |
1994-02-08 |
2023-08-12 |
rat |
B Glenthøj, J Mogensen, H Laursen, S Holm, R Hemmingse. Electrical sensitization of the meso-limbic dopaminergic system in rats: a pathogenetic model for schizophrenia. Brain research. vol 619. issue 1-2. 1993-10-20. PMID:8374792. |
the behavioral response to stimulation was suppressed both by the dopamine (da) d2 receptor antagonists haloperidol and raclopride and by the da d1 receptor antagonist sch 23390. |
1993-10-20 |
2023-08-12 |
rat |
S O Ogren, B Pak. Effects of dopamine D1 and D2 receptor agonists and antagonists on seizures induced by chemoconvulsants in mice. Pharmacology & toxicology. vol 72. issue 4-5. 1993-10-12. PMID:8103921. |
the dopamine d2 antagonists remoxipride (5-20 mg/kg) and raclopride (5-20 mg/kg), haloperidol (2.5 and 5 mg/kg) and the d1 antagonist sch 23390 (0.3, 1.5 mg/kg) did not markedly modify seizures induced by pentylenetetrazole, picrotoxin or bicuculline. |
1993-10-12 |
2023-08-12 |
mouse |
A Imperato, M C Obinu, M A Casu, M S Mascia, L Dazzi, G L Gess. Evidence that neuroleptics increase striatal acetylcholine release through stimulation of dopamine D1 receptors. The Journal of pharmacology and experimental therapeutics. vol 266. issue 2. 1993-09-17. PMID:8102643. |
administration of the d1 receptor antagonist sch 23390 (0.1 mg/kg s.c.) decreased ach output by 30%, completely suppressed the stimulant effect of (-)-sulpiride and haloperidol and only modestly reduced that of clozapine. |
1993-09-17 |
2023-08-12 |
rat |
D V Widzowski, D A Cory-Slecht. Apparent mediation of the stimulus properties of a low dose of quinpirole by dopaminergic autoreceptors. The Journal of pharmacology and experimental therapeutics. vol 266. issue 2. 1993-09-17. PMID:8355188. |
neither the d1 agonist skf38393, the indirect d1/d2 agonist d-amphetamine, the d2 antagonist haloperidol or coadministration of sch 23390 and d-amphetamine substituted for quin. |
1993-09-17 |
2023-08-12 |
rat |
J A Stivers, M T Kaltwasser, P S Hill, V J Hruby, J N Crawle. Ventral tegmental oxytocin induces grooming. Peptides. vol 9 Suppl 1. 1993-06-21. PMID:2856647. |
the dopamine d-2 receptor antagonist, haloperidol, and the d-1 receptor antagonist, sch 23390, when microinjected into the vta five minutes before microinjection of oxy into the vta, did not block oxy-induced grooming, suggesting that oxy is not working through a dopamine autoreceptor on the vta neurons. |
1993-06-21 |
2023-08-11 |
rat |
J A Stivers, M T Kaltwasser, P S Hill, V J Hruby, J N Crawle. Ventral tegmental oxytocin induces grooming. Peptides. vol 9 Suppl 1. 1993-06-21. PMID:2856647. |
systemic pretreatment with haloperidol and sch 23390 effectively blocked grooming induced by oxy in the vta, suggesting that oxy is directly stimulating oxy receptors on vta neurons to release dopamine at postsynaptic sites regulating grooming behaviors. |
1993-06-21 |
2023-08-11 |
rat |
M Hadjiconstantinou, T A Wemlinger, C P Sylvia, J P Hubble, N H Nef. Aromatic L-amino acid decarboxylase activity of mouse striatum is modulated via dopamine receptors. Journal of neurochemistry. vol 60. issue 6. 1993-06-15. PMID:8492125. |
aromatic l-amino acid decarboxylase (aaad) activity is enhanced in the striatum of control and mptp-treated mice after administration of a single dose of the dopamine receptor antagonists haloperidol, sulpiride, and sch 23390. |
1993-06-15 |
2023-08-12 |
mouse |
F Amenta, P Gallo, A Rossodivita, A Ricc. Radioligand binding and autoradiographic analysis of dopamine receptors in the human heart. Naunyn-Schmiedeberg's archives of pharmacology. vol 347. issue 2. 1993-05-20. PMID:8386324. |
these effects were abolished by the beta-adrenoceptor antagonist (-)-propranolol, but not by the d1 receptor antagonist sch 23390 or by the non selective d1/d2 receptor antagonist haloperidol. |
1993-05-20 |
2023-08-12 |
human |
T Yamamoto, M Ohno, K Sugimachi, S Uek. Discriminative stimulus properties of NIK-247 and tetrahydroaminoacridine, centrally active cholinesterase inhibitors, in rats. Pharmacology, biochemistry, and behavior. vol 44. issue 4. 1993-05-11. PMID:8469688. |
however, neither the nik-247 nor the tha stimulus was antagonized by the dopamine antagonists haloperidol, sch 23390, and sulpiride. |
1993-05-11 |
2023-08-12 |
rat |
E P Prinssen, B A Ellenbroek, B Stamatovic, A R Cool. The effects of haloperidol and raclopride in the paw test are influenced similarly by SCH 39166. European journal of pharmacology. vol 231. issue 2. 1993-04-20. PMID:8095900. |
the effects of haloperidol and raclopride in the paw test are influenced similarly by sch 39166. |
1993-04-20 |
2023-08-12 |
Not clear |
E P Prinssen, B A Ellenbroek, B Stamatovic, A R Cool. The effects of haloperidol and raclopride in the paw test are influenced similarly by SCH 39166. European journal of pharmacology. vol 231. issue 2. 1993-04-20. PMID:8095900. |
sch 39166 enhanced the haloperidol- and raclopride-induced effects on frt, whereas neither haloperidol nor raclopride enhanced the sch 39166-induced effects upon this parameter. |
1993-04-20 |
2023-08-12 |
Not clear |
X B Pascaud, M Chovet, C Roze, J L Junie. Neuropeptide Y and sigma receptor agonists act through a common pathway to stimulate duodenal alkaline secretion in rats. European journal of pharmacology. vol 231. issue 3. 1993-04-15. PMID:8449231. |
administration of haloperidol, bmy 14802, devazepide, hexamethonium, tetrodotoxin and by bilateral truncal vagotomy, but not by sch 23390, sulpiride, prazosin or atropine, whereas i.c.v. |
1993-04-15 |
2023-08-12 |
mouse |