| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Verma, S K Kulkarn. D1/D2 dopamine and N-methyl-D-aspartate (NMDA) receptor participation in experimental catalepsy in rats. Psychopharmacology. vol 109. issue 4. 1995-04-04. PMID:1365866. |
mk-801 (0.025-0.5 mg/kg), a non-competitive n-methyl-d-aspartate (nmda) receptor antagonist, reduced the cataleptogenic effects of perphenazine, haloperidol as well as sch 23390. |
1995-04-04 |
2023-08-11 |
rat |
| H Lublin, J Gerlach, L Peacoc. Chronic treatment with the D1 receptor antagonist, SCH 23390, and the D2 receptor antagonist, raclopride, in cebus monkeys withdrawn from previous haloperidol treatment. Extrapyramidal syndromes and dopaminergic supersensitivity. Psychopharmacology. vol 112. issue 2-3. 1995-03-30. PMID:7871047. |
chronic treatment with the d1 receptor antagonist, sch 23390, and the d2 receptor antagonist, raclopride, in cebus monkeys withdrawn from previous haloperidol treatment. |
1995-03-30 |
2023-08-12 |
monkey |
| G Mereu, V Lilliu, P Vargiu, A L Muntoni, M Diana, G L Gess. Depolarization inactivation of dopamine neurons: an artifact? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 2. 1995-03-29. PMID:7869090. |
to investigate on the possible role played by da receptor subtypes, three representatives da antagonists were used: haloperidol (a mixed d1/d2), (-)-sulpiride (a selective d2) and sch 23390 (a selective d1). |
1995-03-29 |
2023-08-12 |
rat |
| G Mereu, V Lilliu, P Vargiu, A L Muntoni, M Diana, G L Gess. Depolarization inactivation of dopamine neurons: an artifact? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 2. 1995-03-29. PMID:7869090. |
however, when neuronal sampling was performed in unanesthetized rats, the single administration of haloperidol, (-)-sulpiride, or sch 23390 (0.5, 25, and 0.3 mg/kg respectively 2-3 hr beforehand) increased the number of spontaneously active a9 and a10 da neurons and their firing rate, whereas the chronic administration of these drugs (daily for 21-28 d) failed to reduce the number of spontaneously active a9 and a10 da neurons. |
1995-03-29 |
2023-08-12 |
rat |
| Y Hatta, S Hatta, T Sait. Effects of ceruletide on the dopamine receptor-adenylate cyclase system in striatum and frontal cortex of rats chronically treated with haloperidol. Psychopharmacology. vol 110. issue 4. 1995-03-29. PMID:7870906. |
chronic treatment of rats with haloperidol decanoate (30 mg/kg and 100 mg/kg im every 4 weeks for 52 weeks) increased [3h] sch 23390 binding in striatal membranes by 25% and 50% and in frontal cortical membranes by 56% and 125% in 30 and 100 mg/kg haloperidol treatment groups, respectively. |
1995-03-29 |
2023-08-12 |
rat |
| R De Beun, H W Rijk, C L Broekkam. Cross-familiarisation conditioned taste aversion procedure as a method to reveal stimulus resemblance between drugs: studies on the 5-HT1A agonist 8-OHDPAT. Psychopharmacology. vol 112. issue 1. 1995-03-29. PMID:7871000. |
pre-exposure to apomorphine, diazepam, sch 23390, licl, spiperone, doi, spiroxatrine, umespirone, pindolol, mcpp, haloperidol, mk 212, clonidine, quipazine and also 5-meodmt was not effective in completely abolishing the cta produced by 8-ohdpat. |
1995-03-29 |
2023-08-12 |
mouse |
| J L Katz, J M Witki. Behavioral effects of dopaminergic agonists and antagonists alone and in combination in the squirrel monkey. Psychopharmacology. vol 113. issue 1. 1995-03-20. PMID:7862823. |
under the fixed-interval schedule, the d2 antagonists, spiperone (0.003-0.006 mg/kg) and haloperidol (0.003-0.01 mg/kg), and the d1 antagonist, sch 23390 (0.03 mg/kg), shifted the quinpirole dose-effect curve to the right. |
1995-03-20 |
2023-08-12 |
monkey |
| M J Ginski, J M Witki. Sensitive and rapid behavioral differentiation of N-methyl-D-aspartate receptor antagonists. Psychopharmacology. vol 114. issue 4. 1995-03-16. PMID:7855218. |
competitive nmda antagonists (ly 274614, ly 233536, cpp, npc 12626), sigma receptor ligands (dtg, dextromethorphan), postsynaptic dopamine agonists (quinpirole, skf 38393) and antagonists (haloperidol, sch 39166), and some depressant compounds (morphine, diazepam) increased failures on the screen test but decreased locomotor activity. |
1995-03-16 |
2023-08-12 |
mouse |
| B D Kretschme. Felbamate, an anti-convulsive drug, has anti-parkinsonian potential in rats. Neuroscience letters. vol 179. issue 1-2. 1995-03-09. PMID:7845605. |
the potency of felbamate, an anti-convulsive drug, to influence dopamine d1 (sch 23390) and d2 (haloperidol) receptor-mediated catalepsy (akinesia and bradykinesia) was studied in rats. |
1995-03-09 |
2023-08-12 |
rat |
| F R Sharp, M Butman, J Koistinaho, K Aardalen, R Nakki, S M Massa, R A Swanson, S M Saga. Phencyclidine induction of the hsp 70 stress gene in injured pyramidal neurons is mediated via multiple receptors and voltage gated calcium channels. Neuroscience. vol 62. issue 4. 1995-03-07. PMID:7845588. |
several neurotransmitter receptor antagonists inhibited induction of hsp70 produced by phencyclidine (50 mg/kg): haloperidol (ed50 = 0.8 mg/kg), clozapine (ed50 = 1 mg/kg), valium (ed50 = 1 mg/kg), sch 23390 (ed50 = 7 mg/kg) and muscimol (ed50 = 3 mg/kg). |
1995-03-07 |
2023-08-12 |
rat |
| B Ferger, W Kropf, K Kuschinsk. Studies on electroencephalogram (EEG) in rats suggest that moderate doses of cocaine or d-amphetamine activate D1 rather than D2 receptors. Psychopharmacology. vol 114. issue 2. 1995-02-27. PMID:7838923. |
these effects of both drugs were mimicked by the selective agonist at d1 receptors sk&f 38393 (3 mg/kg sc) and were reversed by the antagonist at d1 receptors sch 23390 (0.2 mg/kg ip) but not influenced by haloperidol (0.1 mg/kg ip) in a dose which is likely to block d2 rather than d1 receptors. |
1995-02-27 |
2023-08-12 |
rat |
| J L Cornish, M van den Buus. Pressor responses to electrical and chemical stimulation of the rat brain A10 dopaminergic system. Neuroscience letters. vol 176. issue 2. 1995-02-21. PMID:7530350. |
these pressor responses could be significantly attenuated by pretreatment with the dopamine d2 receptor antagonist haloperidol, but not the d1 receptor antagonist sch 23390. |
1995-02-21 |
2023-08-12 |
rat |
| V L Coffin, D McHuch, R E Chipkin, A Barnet. SCH 39166, a potential antipsychotic drug, does not evoke movement disorders in cebus monkeys. Neurochemistry international. vol 20 Suppl. 1995-01-30. PMID:1365413. |
in contrast to haloperidol, weekly administration of sch 39166 for 14 weeks did not produce abnormal movements but did produce equivalent sedative effects. |
1995-01-30 |
2023-08-11 |
monkey |
| J Diaz, D Lévesque, N Griffon, C H Lammers, M P Martres, P Sokoloff, J C Schwart. Opposing roles for dopamine D2 and D3 receptors on neurotensin mRNA expression in nucleus accumbens. The European journal of neuroscience. vol 6. issue 8. 1994-12-30. PMID:7981879. |
in rats treated by haloperidol and sulpiride, two d2-like receptor antagonists, but not by sch 23390, a d1-like receptor antagonist, proneurotensin mrna was increased in the d2 receptor mrna-rich areas but decreased in the d3 receptor mrna-rich areas. |
1994-12-30 |
2023-08-12 |
rat |
| G Mittleman, A L Rosner, C L Schau. Polydipsia and dopamine: behavioral effects of dopamine D1 and D2 receptor agonists and antagonists. The Journal of pharmacology and experimental therapeutics. vol 271. issue 2. 1994-12-29. PMID:7965779. |
the role of dopamine d1 and d2 receptors was investigated by comparing the behavioral effects of dopamine d1 agonists (skf 38393 and skf 82958) and antagonists (sch 23390 and skf 83566) to those of a dopamine d2 agonist (quinpirole) and antagonist (haloperidol) by using an animal model of excessive water consumption, drinking evoked in the sip paradigm. |
1994-12-29 |
2023-08-12 |
Not clear |
| B Hitzemann, K Dains, S Kanes, R Hitzeman. Further studies on the relationship between dopamine cell density and haloperidol-induced catalepsy. The Journal of pharmacology and experimental therapeutics. vol 271. issue 2. 1994-12-29. PMID:7965819. |
at the fourth selected generation (s4), the nr/np and nnr/np lines differed more than 5-fold in their haloperidol ed50, but showed no difference in their ed50 to sch 23390. |
1994-12-29 |
2023-08-12 |
mouse |
| B Zadow, W J Schmid. Lesions of the entopeduncular nucleus and the subthalamic nucleus reduce dopamine receptor antagonist-induced catalepsy in the rat. Behavioural brain research. vol 62. issue 1. 1994-11-04. PMID:7917035. |
five days after bilateral lesions of ep and stn respectively with the excitotoxin quinolinic acid (15, 30 nmol/0.5 microliter/side and 24 nmol/0.5 microliter/side, respectively) rats were injected intraperitoneally with the dopamine d1 receptor antagonist sch 23390 (0.5 mg/kg) or the dopamine d2 receptor antagonist haloperidol (0.5 mg/kg). |
1994-11-04 |
2023-08-12 |
rat |
| P M Callahan, K A Cunningha. Involvement of 5-HT2C receptors in mediating the discriminative stimulus properties of m-chlorophenylpiperazine (mCPP). European journal of pharmacology. vol 257. issue 1-2. 1994-10-10. PMID:8082704. |
the dopamine receptor antagonists sch 23390 and haloperidol were also ineffective mcpp antagonists. |
1994-10-10 |
2023-08-12 |
rat |
| T J Parry, K Eberle-Wang, I Lucki, M F Chessele. Dopaminergic stimulation of subthalamic nucleus elicits oral dyskinesia in rats. Experimental neurology. vol 128. issue 2. 1994-10-04. PMID:7915675. |
orofacial movements elicited by local infusion of apomorphine (1.0 microgram) into the sth were blocked by peripheral administration of the d1 antagonist, sch 23390 (0.1 mg/kg, sc), but not by the d2 antagonists haloperidol (1.0 mg/kg, sc) or sulpiride (50 mg/kg, sc). |
1994-10-04 |
2023-08-12 |
rat |
| L Kostal, C J Savor. Influence of pharmacological manipulation of dopamine and opioid receptor subtypes on stereotyped behaviour of restricted-fed fowls. Pharmacology, biochemistry, and behavior. vol 48. issue 1. 1994-08-10. PMID:8029296. |
with dopamine antagonists, inhibition of both stereotypes was most marked with haloperidol (d2), intermediate with clozapine (d4), and lowest with sch 23390 (d1). |
1994-08-10 |
2023-08-12 |
Not clear |