| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Cohen, G Perrault, D J Sange. Evidence for the involvement of dopamine receptors in ethanol-induced hyperactivity in mice. Neuropharmacology. vol 36. issue 8. 1998-01-07. PMID:9294975. |
the stimulant effect of ethanol was blocked by the d2/d3 antagonists, haloperidol (0.2 mg/kg) and tiapride (30-60 mg/kg), and by the d1 antagonist, sch 23390 (0.03 mg/kg) whereas the non selective da antagonist, clozapine decreased ethanol-induced hyperactivity at a dose (1 mg/kg) which also decreased activity in control animals. |
1998-01-07 |
2023-08-12 |
mouse |
| C Cohen, G Perrault, D J Sange. Evidence for the involvement of dopamine receptors in ethanol-induced hyperactivity in mice. Neuropharmacology. vol 36. issue 8. 1998-01-07. PMID:9294975. |
unlike haloperidol and clozapine which potentiated lrr induced by ethanol, the selective da antagonists, tiapride and sch 23390, had no effect. |
1998-01-07 |
2023-08-12 |
mouse |
| N Kawai, Y Takamatsu, H Yamamoto, E Hasegawa, A Baba, T Suzuki, T Moroji, O O Ogunrem. Effect of methamphetamine and dopamine receptor antagonists on cholecystokininlike immunoreactivity in the rat medial prefrontal cortex. Pharmacology, biochemistry, and behavior. vol 58. issue 2. 1997-12-01. PMID:9300613. |
this report examines the effects of various dopamine (da) receptor antagonists [haloperidol (hal), sulpiride (sul), ym09151-2 (ym), and sch23390 (sch)] on map-induced abnormal behaviors and the changes of cck-li in the rat mpfc. |
1997-12-01 |
2023-08-12 |
rat |
| B D Kretschmer, U Kratzer, K Breithecker, M Koc. ACEA 1021, a glycine site antagonist with minor psychotomimetic and amnestic effects in rats. European journal of pharmacology. vol 331. issue 2-3. 1997-10-27. PMID:9274968. |
anti-cataleptic properties of acea 1021 in dopamine d2 (haloperidol (4'fluoro-4-(1-(4-hydroxy-4-p-chlorophenyl-piperidino)-butyrophe non)) or d1 (sch 23390 (7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzaze pin e hydrochloride)) receptor antagonist-pretreated rats were only minor. |
1997-10-27 |
2023-08-12 |
rat |
| M Bubser, B Zadow, U O Kronthaler, U Felsheim, N G Rückert, W J Schmid. Behavioural pharmacology of the non-competitive NMDA antagonists dextrorphan and ADCI: relations between locomotor stimulation, anticataleptic potential and forebrain dopamine metabolism. Naunyn-Schmiedeberg's archives of pharmacology. vol 355. issue 6. 1997-08-27. PMID:9205962. |
both dextrorphan and adci dose-dependently antagonized catalepsy induced by the d-1 dopamine receptor antagonist sch 23390 or the d-2 dopamine receptor antagonist haloperidol. |
1997-08-27 |
2023-08-12 |
rat |
| J Maj, Z Rogóz, G Skuza, K Kołodziejczy. The behavioural effects of pramipexole, a novel dopamine receptor agonist. European journal of pharmacology. vol 324. issue 1. 1997-07-24. PMID:9137910. |
used in low doses (0.001-0.1 mg/kg), pramipexole induced locomotor hypoactivity which was antagonized by a low dose of spiperone; at higher doses (0.3, 1 mg/kg) it evoked hyperactivity which was inhibited by haloperidol, sulpiride and clozapine, but not by sch 23390 (r(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1h-3- benzazepine hydrochloride). |
1997-07-24 |
2023-08-12 |
mouse |
| S Florin, C Suaudeau, J C Meunier, J Costenti. Orphan neuropeptide NocII, a putative pronociceptin maturation product, stimulates locomotion in mice. Neuroreport. vol 8. issue 3. 1997-07-03. PMID:9106751. |
the motor stimulant action of nocii appears to depend largely on dopamine transmission since it is totally reversed by the d1 or the d2 dopamine receptor antagonists sch 23390 and haloperidol. |
1997-07-03 |
2023-08-12 |
mouse |
| S B Schwarzkopf, J P Bruno, T Mitra, J R Iso. Effects of haloperidol and SCH 23390 on acoustic startle in animals depleted of dopamine as neonates: implications for neuropsychiatric syndromes. Psychopharmacology. vol 123. issue 3. 1997-06-13. PMID:8833419. |
effects of haloperidol and sch 23390 on acoustic startle in animals depleted of dopamine as neonates: implications for neuropsychiatric syndromes. |
1997-06-13 |
2023-08-12 |
rat |
| S B Schwarzkopf, J P Bruno, T Mitra, J R Iso. Effects of haloperidol and SCH 23390 on acoustic startle in animals depleted of dopamine as neonates: implications for neuropsychiatric syndromes. Psychopharmacology. vol 123. issue 3. 1997-06-13. PMID:8833419. |
animals underwent startle testing as adults (60-75 days of age) after administration of da antagonists (haloperidol: 0.1 or 0.3 mg/kg, sch 23390:0.01 or 0.05 mg/kg) with and without da agonist administration (apomorphine 0.5 mg/kg). |
1997-06-13 |
2023-08-12 |
rat |
| E Meller, K Bohmake. Chronic treatment with antipsychotic drugs does not alter G protein alpha or beta subunit levels in rat brain. Neuropharmacology. vol 35. issue 12. 1997-06-12. PMID:9076758. |
groups of rats received once daily subcutaneous treatments for 22 days with haloperidol (0.5 mg/kg), clozapine (20 mg/kg), sch 23390 (0.2 mg/kg) or vehicle. |
1997-06-12 |
2023-08-12 |
rat |
| D A Cory-Slechta, C L Zuch, R A Fo. Comparison of the stimulus properties of a pre- vs. a putative postsynaptic dose of quinpirole. Pharmacology, biochemistry, and behavior. vol 55. issue 3. 1997-05-08. PMID:8951984. |
the 0.20 quin stimulus was antagonized by the d2 blocker haloperidol and partially blocked by the d1 antagonist sch 23390. |
1997-05-08 |
2023-08-12 |
Not clear |
| S M Dursun, S L Handle. Similarities in the pharmacology of spontaneous and DOI-induced head-shakes suggest 5HT2A receptors are active under physiological conditions. Psychopharmacology. vol 128. issue 2. 1997-04-10. PMID:8956381. |
ritanserin, ketanserin, prazosin, haloperidol, pimozide, sch 23390 and sch 39166 potently and dose-dependently antagonised both types of hs while sulpiride and raclopride produced weak and partial antagonism. |
1997-04-10 |
2023-08-12 |
Not clear |
| K Shiosaki, K E Asin, D R Britton, W J Giardina, L Bednarz, L Mahan, J Mikusa, A Nikkel, C Wisme. Hyperactivity and behavioral seizures in rodents following treatment with the dopamine D1 receptor agonists A-86929 and ABT-431. European journal of pharmacology. vol 317. issue 2-3. 1997-04-03. PMID:8997599. |
in rats, a-86929 produced a dose-dependent increase in locomotor activity that was attenuated by the selective dopamine d1 receptor antagonist, sch 23390, as well as by higher doses of the dopamine d2 receptor antagonist, haloperidol. |
1997-04-03 |
2023-08-12 |
mouse |
| K Ishida, Y Ohno, T Ishibashi, M Nakamur. Effects of SM-9018, a novel 5-HT2 and D2 receptor antagonist, on electrically-evoked [3H]acetylcholine release from rat striatal slices. General pharmacology. vol 27. issue 7. 1997-04-01. PMID:8981068. |
the relative potencies of the neuroleptics in antagonizing the qpl action were nemonapride > haloperidol approximately equal to sm-9018 > > chlorpromazine > > sch 23390, and the rank order, except for nemonapride, was consistent with their binding affinities to striatal d2 receptors. |
1997-04-01 |
2023-08-12 |
rat |
| T F Meert, P De Haes, N Aerts, G Clinck. Antagonism of the discriminative stimulus properties of cocaine with the combination of a dopamine D1 and D2 antagonist. Acta neurobiologiae experimentalis. vol 56. issue 4. 1997-03-18. PMID:9033125. |
antagonism of the discriminative stimulus properties of 10 mg/kg cocaine was studied in rats by use of the dopamine d1 antagonist sch 23390 and the d2 antagonist haloperidol. |
1997-03-18 |
2023-08-12 |
rat |
| T F Meert, P De Haes, N Aerts, G Clinck. Antagonism of the discriminative stimulus properties of cocaine with the combination of a dopamine D1 and D2 antagonist. Acta neurobiologiae experimentalis. vol 56. issue 4. 1997-03-18. PMID:9033125. |
whereas sch 23390 and haloperidol were by themselves unable to antagonize the cueing properties of cocaine, the combination of both dopamine antagonists resulted in a complete blockade of the cocaine cue. |
1997-03-18 |
2023-08-12 |
rat |
| T F Meert, P De Haes, N Aerts, G Clinck. Antagonism of the discriminative stimulus properties of cocaine with the combination of a dopamine D1 and D2 antagonist. Acta neurobiologiae experimentalis. vol 56. issue 4. 1997-03-18. PMID:9033125. |
in the presence of a fixed dose of 0.01 and 0.04 mg/kg haloperidol, the ed50's (it is the effective dose in 50% of the animals) of sch 23390 for cocaine antagonism were 0.043 and 0.012 mg/kg, respectively. |
1997-03-18 |
2023-08-12 |
rat |
| T F Meert, P De Haes, N Aerts, G Clinck. Antagonism of the discriminative stimulus properties of cocaine with the combination of a dopamine D1 and D2 antagonist. Acta neurobiologiae experimentalis. vol 56. issue 4. 1997-03-18. PMID:9033125. |
similarly, the ed50's of haloperidol in combination with 0.01 and 0.04 mg/kg sch 23390 were 0.021 and 0.024 mg/kg. |
1997-03-18 |
2023-08-12 |
rat |
| T F Meert, P De Haes, N Aerts, G Clinck. Antagonism of the discriminative stimulus properties of cocaine with the combination of a dopamine D1 and D2 antagonist. Acta neurobiologiae experimentalis. vol 56. issue 4. 1997-03-18. PMID:9033125. |
the combined treatment of haloperidol and sch 23390 resulted in strong response-rate reductions. |
1997-03-18 |
2023-08-12 |
rat |
| B Geter-Douglass, A L Rile. Dopamine D1/D2 antagonist combinations as antagonists of the discriminative stimulus effects of cocaine. Pharmacology, biochemistry, and behavior. vol 54. issue 2. 1997-02-12. PMID:8743607. |
the ability of various combinations of the d1 antagonist, sch 23,390, and the d2 antagonist, haloperidol, were tested for their ability to block the cocaine stimulus in rats trained to discriminate cocaine (7.5, 10, or 13 mg/kg) from vehicle. |
1997-02-12 |
2023-08-12 |
rat |