| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Malika El Yacoubi, Jean Costentin, Jean-Marie Vaugeoi. Adenosine A2A receptors and depression. Neurology. vol 61. issue 11 Suppl 6. 2004-02-11. PMID:14663017. |
in support of this idea, administration of the dopamine d2 receptor antagonist haloperidol prevented antidepressant-like effects elicited by sch 58261 in the forced swim test (putatively involving cortex), whereas it had no effect on stimulant motor effects of sch 58261 (putatively linked to ventral striatum). |
2004-02-11 |
2023-08-12 |
mouse |
| Malika El Yacoubi, Jean Costentin, Jean-Marie Vaugeoi. Adenosine A2A receptors and depression. Neurology. vol 61. issue 11 Suppl 6. 2004-02-11. PMID:14663017. |
the interaction profile of caffeine with haloperidol differed markedly from that of sch 58261 in the forced swim and motor activity tests. |
2004-02-11 |
2023-08-12 |
mouse |
| Lance R McMahon, Kathryn A Cunningha. Discriminative stimulus effects of (-)-ephedrine in rats: analysis with catecholamine transporter and receptor ligands. Drug and alcohol dependence. vol 70. issue 3. 2004-02-04. PMID:12757963. |
the (-)-ephedrine cue was antagonized by the d(1)-like antagonist sch 23390 and the alpha(1)-adrenoceptor antagonist prazosin as well as the d(2)-like antagonists (-)-eticlopride and haloperidol, although only at doses that disrupted responding in some rats. |
2004-02-04 |
2023-08-12 |
rat |
| Michael R Drew, Stephen Fairhurst, Chara Malapani, Jon C Horvitz, Peter D Balsa. Effects of dopamine antagonists on the timing of two intervals. Pharmacology, biochemistry, and behavior. vol 75. issue 1. 2004-01-07. PMID:12759108. |
test sessions were conducted in which either the d(1) antagonist sch-23390 (sch; 0.02, 0.04, 0.06 mg/kg) or the d(2) antagonist haloperidol (hal; 0.05, 0.1, 0.2 mg/kg) were injected prior to testing. |
2004-01-07 |
2023-08-12 |
rat |
| Jadwiga Wardas, Małgorzata Pietraszek, Marta Dziedzicka-Wasylewsk. SCH 58261, a selective adenosine A2A receptor antagonist, decreases the haloperidol-enhanced proenkephalin mRNA expression in the rat striatum. Brain research. vol 977. issue 2. 2003-09-02. PMID:12834887. |
since it is believed that main motor symptoms of pd are due to the overactivity of the gabaergic striopallidal pathway, the aim of the present study was to find out whether sch 58261, a selective antagonist of the adenosine a(2a) receptors, is capable of counteracting both the catalepsy and the enhancement of proenkephalin (penk) mrna expression in the rat striatum, induced by haloperidol administered at 1.5 mg/kg s.c. 3 times, every 3 h. systemic administration of sch 58261 (5 mg/kg i.p., 3 times, every 3 h, 10 min before haloperidol), partially decreased the haloperidol-induced catalepsy and the increase in the penk mrna expression in both dorsolateral and ventrolateral parts of the striatum at all three examined levels. |
2003-09-02 |
2023-08-12 |
rat |
| Jadwiga Wardas, Małgorzata Pietraszek, Marta Dziedzicka-Wasylewsk. SCH 58261, a selective adenosine A2A receptor antagonist, decreases the haloperidol-enhanced proenkephalin mRNA expression in the rat striatum. Brain research. vol 977. issue 2. 2003-09-02. PMID:12834887. |
the present results suggest that similarly to other a(2a) receptor antagonists, sch 58261 normalizes activity of the striopallidal pathway, enhanced by blockade of dopamine d(2) receptors with haloperidol, which may result in recovery of motor functions. |
2003-09-02 |
2023-08-12 |
rat |
| Juei-Tang Cheng, Dong-Yih Ku. Both alpha1-adrenergic and D(1)-dopaminergic neurotransmissions are involved in phenylpropanolamine-mediated feeding suppression in mice. Neuroscience letters. vol 347. issue 2. 2003-08-20. PMID:12873745. |
in addition, pretreatment of haloperidol or sch 23390 could also partly block ppa anorexia, revealing the involvement of d(1) receptor subtype. |
2003-08-20 |
2023-08-12 |
mouse |
| Daphna Joel, Julia Doljansk. Selective alleviation of compulsive lever-pressing in rats by D1, but not D2, blockade: possible implications for the involvement of D1 receptors in obsessive-compulsive disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 1. 2003-03-17. PMID:12496943. |
in addition, haloperidol at doses that decreased lever-pressing in the post-training signal attenuation procedure (0.036 and 0.05 mg/kg) had a similar effect in regular extinction, whereas an sch 23390 dose that decreased compulsive lever-pressing in the post-training signal attenuation procedure (0.01 mg/kg) had no effect on regular extinction. |
2003-03-17 |
2023-08-12 |
rat |
| Karen M Trimble, Robert Bell, David J Kin. Effects of the selective dopamine D(1) antagonists NNC 01-0112 and SCH 39166 on latent inhibition in the rat. Physiology & behavior. vol 77. issue 1. 2002-12-04. PMID:12213509. |
we investigated the effects of haloperidol (0.1 mg/kg) and two selective d(1) antagonists, nnc 01-0112 (0.05, 0.1 and 0.2 mg/kg) and sch 39166 (0.02, 0.2 and 2.0 mg/kg), on latent inhibition (li) in rats. |
2002-12-04 |
2023-08-12 |
rat |
| G Colombo, S Melis, G Brunetti, S Serra, G Vacca, M A Carai, G L Gess. GABA(B) receptor inhibition causes locomotor stimulation in mice. European journal of pharmacology. vol 433. issue 1. 2002-07-25. PMID:11755139. |
the locomotor stimulation elicited by sch 50911 was completely blocked by haloperidol (0.1 mg/kg, i.p. |
2002-07-25 |
2023-08-12 |
mouse |
| Gurpreet Kaur, Shrinivas K Kulkarn. Studies on modulation of feeding behavior by atypical antipsychotics in female mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 2. 2002-07-22. PMID:11817504. |
the aim of this study was to examine the effects of different doses of typical antipsychotics, chlorpromazine (0.25-1 mg/kg) and haloperidol (0.25-1 mg/kg), and atypical antipsychotics, clozapine (0.5-2 mg/kg), olanzapine (0.25-1 mg/kg), risperidone (0.5-2 mg/kg), sulpiride (10-40 mg/kg) and dopamine d1 antagonist, sch 23390 (0.25-1 mg/kg) on feeding behavior at different time intervals after acute administration. |
2002-07-22 |
2023-08-12 |
mouse |
| D Joel, A Avisar, J Doljansk. Enhancement of excessive lever-pressing after post-training signal attenuation in rats by repeated administration of the D1 antagonist SCH 23390 or the D2 agonist quinpirole, but not the D1 agonist SKF 38393 or the D2 antagonist haloperidol. Behavioral neuroscience. vol 115. issue 6. 2002-05-07. PMID:11770060. |
enhancement of excessive lever-pressing after post-training signal attenuation in rats by repeated administration of the d1 antagonist sch 23390 or the d2 agonist quinpirole, but not the d1 agonist skf 38393 or the d2 antagonist haloperidol. |
2002-05-07 |
2023-08-12 |
rat |
| D Joel, A Avisar, J Doljansk. Enhancement of excessive lever-pressing after post-training signal attenuation in rats by repeated administration of the D1 antagonist SCH 23390 or the D2 agonist quinpirole, but not the D1 agonist SKF 38393 or the D2 antagonist haloperidol. Behavioral neuroscience. vol 115. issue 6. 2002-05-07. PMID:11770060. |
the present study shows that repeated administration of sch 23390 or quinpirole, but not skf 38393 or haloperidol, enhances this behavioral pattern. |
2002-05-07 |
2023-08-12 |
rat |
| J Wardas, J Konieczny, E Lorenc-Koc. SCH 58261, an A(2A) adenosine receptor antagonist, counteracts parkinsonian-like muscle rigidity in rats. Synapse (New York, N.Y.). vol 41. issue 2. 2001-08-23. PMID:11400182. |
moreover, sch 58261 in doses of 1 and 5 mg/kg abolished muscle resistance induced by haloperidol (0.5 mg/kg). |
2001-08-23 |
2023-08-12 |
rat |
| J Wardas, J Konieczny, E Lorenc-Koc. SCH 58261, an A(2A) adenosine receptor antagonist, counteracts parkinsonian-like muscle rigidity in rats. Synapse (New York, N.Y.). vol 41. issue 2. 2001-08-23. PMID:11400182. |
however, only the highest dose of sch 58261 (5 mg/kg) decreased tonic emg activity enhanced by haloperidol. |
2001-08-23 |
2023-08-12 |
rat |
| N Sharan, V D Nair, R K Mishr. Modulation of a 40-kDa catecholamine regulated protein by dopamine receptor antagonists. European journal of pharmacology. vol 413. issue 1. 2001-07-12. PMID:11173065. |
chronic treatment with dopamine d2 receptor antagonist haloperidol in rats significantly increased the levels of crp40 in the striatum, whereas, chronic r(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine (sch 23390) dopamine d1 receptor antagonist administration significantly decreased striatal crp40 levels. |
2001-07-12 |
2023-08-12 |
rat |
| C Manzanedo, M A Aguilar, M Rodríguez-Arias, J Miñarr. Effects of dopamine antagonists with different receptor blockade profiles on morphine-induced place preference in male mice. Behavioural brain research. vol 121. issue 1-2. 2001-06-28. PMID:11275296. |
the effects of dopamine (da) antagonists with different selectivity for the da receptors (sch 23390, 0.5, 0.25, 0.125 mg/kg; haloperidol, 0.2, 0.1 mg/kg; raclopride, 1.2, 0.6, 0.3 mg/kg; risperidone, 0.4, 0.2, 0.1 mg/kg; u-99194a maleate, 40, 20 mg/kg; clozapine, 2.5, 1.25, 0.625 mg/kg) on the acquisition of place conditioning and morphine-induced conditioned place preference (cpp) were explored in male mice. |
2001-06-28 |
2023-08-12 |
mouse |
| C Manzanedo, M A Aguilar, M Rodríguez-Arias, J Miñarr. Effects of dopamine antagonists with different receptor blockade profiles on morphine-induced place preference in male mice. Behavioural brain research. vol 121. issue 1-2. 2001-06-28. PMID:11275296. |
morphine (40 mg/kg) produced cpp while sch 23390, haloperidol and clozapine (highest dose) and risperidone (lowest dose) produced conditioned place aversion (cpa). |
2001-06-28 |
2023-08-12 |
mouse |
| C Manzanedo, M A Aguilar, M Rodríguez-Arias, J Miñarr. Effects of dopamine antagonists with different receptor blockade profiles on morphine-induced place preference in male mice. Behavioural brain research. vol 121. issue 1-2. 2001-06-28. PMID:11275296. |
morphine-induced cpp was reversed by the administration of sch 23390 and risperidone (all doses), haloperidol (highest dose) and raclopride and clozapine (intermediate and lowest doses). |
2001-06-28 |
2023-08-12 |
mouse |
| R A Duffy, M A Hunt, J K Wamsley, R D McQuad. In vivo autoradiography of [3H]SCH 39166 in rat brain: selective displacement by D1/D5 antagonists. Journal of chemical neuroanatomy. vol 19. issue 1. 2000-11-03. PMID:10882836. |
a single concentration of triated sch 39166 was administered to rats, with or without competing doses of the dl/d5 antagonist sch 23390 and unlabeled sch 39166. the d2-like antagonists haloperidol or the 5-ht, antagonist ketanserin. |
2000-11-03 |
2023-08-12 |
rat |