| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P C Contreras, R Quirion, D R Gehlert, M L Contreras, T L O'Donohu. Autoradiographic distribution of non-dopaminergic binding sites labeled by [3H]haloperidol in rat brain. Neuroscience letters. vol 75. issue 2. 1987-06-16. PMID:3033560. |
the regional distribution of binding sites labeled by [3h]haloperidol, in the presence of excess spiroperidol, was compared to the regional distribution of receptors labeled by [3h]sch 23390 and [3h]sulpiride, [3h]sch 23390 and [3h]sulpiride labeled distinct nuclei, such as the olfactory tubercle, caudate, globus pallidus, substantia nigra, and inferior and superior colliculi. |
1987-06-16 |
2023-08-11 |
rat |
| J M Goldstein, L C Litwin, E B Sutton, J B Malic. D-2 dopamine antagonist-like effects of SCH 23390 on A9 and A10 dopamine neurons. Life sciences. vol 40. issue 11. 1987-04-22. PMID:2950291. |
compared to haloperidol, sch 23390 was 5 times more potent on a9 da neurons and 20 times more potent on a10 da neurons. |
1987-04-22 |
2023-08-11 |
Not clear |
| J M Goldstein, L C Litwin, E B Sutton, J B Malic. D-2 dopamine antagonist-like effects of SCH 23390 on A9 and A10 dopamine neurons. Life sciences. vol 40. issue 11. 1987-04-22. PMID:2950291. |
however, the magnitude of the reversal effect was greater with haloperidol than sch 23390. |
1987-04-22 |
2023-08-11 |
Not clear |
| J M Goldstein, L C Litwin, E B Sutton, J B Malic. D-2 dopamine antagonist-like effects of SCH 23390 on A9 and A10 dopamine neurons. Life sciences. vol 40. issue 11. 1987-04-22. PMID:2950291. |
in addition, haloperidol produced a further increase in firing of both a9 and a10 da neurons after sch 23390 maximally increased firing. |
1987-04-22 |
2023-08-11 |
Not clear |
| S Barasi, M M Ben-Sreti, A L Clatworthy, K N Duggal, J P Gonzalez, J Robertson, K F Rooney, R D Sewel. Dopamine receptor-mediated spinal antinociception in the normal and haloperidol pretreated rat: effects of sulpiride and SCH 23390. British journal of pharmacology. vol 90. issue 1. 1987-04-17. PMID:3545350. |
dopamine receptor-mediated spinal antinociception in the normal and haloperidol pretreated rat: effects of sulpiride and sch 23390. |
1987-04-17 |
2023-08-11 |
rat |
| S Barasi, M M Ben-Sreti, A L Clatworthy, K N Duggal, J P Gonzalez, J Robertson, K F Rooney, R D Sewel. Dopamine receptor-mediated spinal antinociception in the normal and haloperidol pretreated rat: effects of sulpiride and SCH 23390. British journal of pharmacology. vol 90. issue 1. 1987-04-17. PMID:3545350. |
in animals not treated with haloperidol, the dopamine receptor antagonists sch 23390 and (+/-)-sulpiride both blocked the increase in tfl produced by the d2-agonists. |
1987-04-17 |
2023-08-11 |
rat |
| R T Weathersby, J B Appe. Dopamine D2 receptor mediation of the discriminative stimulus properties of LY 171555 (quinpirole). European journal of pharmacology. vol 132. issue 1. 1987-04-01. PMID:2949989. |
when given in combination with the training drug, haloperidol but not the d1 antagonist sch 23390 dose dependently blocked the ly 171555 cue; given alone, sch 23390 mimicked ly 171555 and haloperidol elicited responding on the saline-appropriate lever. |
1987-04-01 |
2023-08-11 |
rat |
| W C Boyar, C A Alta. Modulation of in vivo dopamine release by D2 but not D1 receptor agonists and antagonists. Journal of neurochemistry. vol 48. issue 3. 1987-03-19. PMID:2949060. |
da release was increased by the d2 antagonists haloperidol and metoclopramide but not by the d1 antagonists sch 23390 and skf 83566. |
1987-03-19 |
2023-08-11 |
mouse |
| G R Breese, G E Duncan, T C Napier, S C Bondy, L C Iorio, R A Muelle. 6-hydroxydopamine treatments enhance behavioral responses to intracerebral microinjection of D1- and D2-dopamine agonists into nucleus accumbens and striatum without changing dopamine antagonist binding. The Journal of pharmacology and experimental therapeutics. vol 240. issue 1. 1987-02-27. PMID:3100767. |
however, chronic haloperidol treatment did not alter significantly [3h]sch 23390 binding to striatal membranes. |
1987-02-27 |
2023-08-11 |
rat |
| J Hytte. Effect of prolonged treatment with neuroleptics on dopamine D-1 and D-2 receptor density in corpus striatum of mice. Acta pharmacologica et toxicologica. vol 59. issue 5. 1987-02-26. PMID:2880451. |
mice were treated daily for 12 days with the selective d-1 antagonist, the benzazepine sch 23390, the mixed d-1/d-2 antagonist zuclopenthixol or the selective d-2 antagonist haloperidol. |
1987-02-26 |
2023-08-11 |
mouse |
| J Hytte. Effect of prolonged treatment with neuroleptics on dopamine D-1 and D-2 receptor density in corpus striatum of mice. Acta pharmacologica et toxicologica. vol 59. issue 5. 1987-02-26. PMID:2880451. |
the study showed that the density of d-2 receptors increased after haloperidol whereas no changes were seen after sch 23390 or zuclopenthixol. |
1987-02-26 |
2023-08-11 |
mouse |
| J Hytte. Effect of prolonged treatment with neuroleptics on dopamine D-1 and D-2 receptor density in corpus striatum of mice. Acta pharmacologica et toxicologica. vol 59. issue 5. 1987-02-26. PMID:2880451. |
the results are in full agreement with published behavioural results where haloperidol induces tolerance whereas sch 23390 or zuclopenthixol do not. |
1987-02-26 |
2023-08-11 |
mouse |
| D Fage, B Scatto. Opposing effects of D-1 and D-2 receptor antagonists on acetylcholine levels in the rat striatum. European journal of pharmacology. vol 129. issue 3. 1987-01-22. PMID:2877889. |
sch 23390 blocked the ability of haloperidol or sulpiride to diminish striatal acetylcholine levels and potentiated the increase in this biochemical parameter induced by the selective d-2 receptor agonist ly 141865. |
1987-01-22 |
2023-08-11 |
rat |
| S L Hartgraves, P K Randal. Dopamine agonist-induced stereotypic grooming and self-mutilation following striatal dopamine depletion. Psychopharmacology. vol 90. issue 3. 1987-01-16. PMID:3097724. |
the dopamine receptor antagonists haloperidol, sch 23390 and sulpiride effectively blocked apomorphine-induced behaviors in dopamine-depleted animals. |
1987-01-16 |
2023-08-11 |
rat |
| L Ståhle, U Ungersted. Effects of neuroleptic drugs on the inhibition of exploratory behaviour induced by a low dose of apomorphine: implications for the identity of dopamine receptors. Pharmacology, biochemistry, and behavior. vol 25. issue 2. 1986-11-21. PMID:2876441. |
apomorphine (0.05 mg/kg) was tested against cis-flupenthixol (0.01-0.5 mg/kg), haloperidol (0.01-0.1 mg/kg), metoclopramide (0.2-5 mg-kg), sulpiride (0.5-50 mg/kg) and sch 23390 (0.005-0.05 mg/kg). |
1986-11-21 |
2023-08-11 |
rat |
| L Ståhle, U Ungersted. Effects of neuroleptic drugs on the inhibition of exploratory behaviour induced by a low dose of apomorphine: implications for the identity of dopamine receptors. Pharmacology, biochemistry, and behavior. vol 25. issue 2. 1986-11-21. PMID:2876441. |
metoclopramide and haloperidol had weak antagonising effects against apomorphine while cis-flupenthixol and sch 23390 was completely inefficient in this respect. |
1986-11-21 |
2023-08-11 |
rat |
| A Boireau, J Chambry, P Dubedat, G Farges, A M Carruette, J L Zundel, J C Blanchar. Enhancing effect of dopamine blockers on evoked acetylcholine release in rat striatal slices: a classical D-2 antagonist response? European journal of pharmacology. vol 128. issue 1-2. 1986-11-17. PMID:2875894. |
the effects of chlorpromazine, pipotiazine, haloperidol, domperidone, sulpiride and sch 23390 on the potassium-evoked release of [3h]acetylcholine [( 3h]ach) were studied in rat striatal slices. |
1986-11-17 |
2023-08-11 |
rat |
| B S Starr, M S Star. Differential effects of dopamine D1 and D2 agonists and antagonists on velocity of movement, rearing and grooming in the mouse. Implications for the roles of D1 and D2 receptors. Neuropharmacology. vol 25. issue 5. 1986-09-16. PMID:3488514. |
a dose of apomorphine (25 micrograms/kg) which is considered to act presynaptically produced haloperidol-resistant sedation, while a larger dose (0.5 mg/kg; with postsynaptic actions) evoked head-down sniffing and ponderous walking that were partially prevented by pretreatment with 0.05 mg/kg haloperidol (d2 blocker), but not 0.01 mg/kg sch 23390 (d1 blocker). |
1986-09-16 |
2023-08-11 |
mouse |
| B S Starr, M S Star. Differential effects of dopamine D1 and D2 agonists and antagonists on velocity of movement, rearing and grooming in the mouse. Implications for the roles of D1 and D2 receptors. Neuropharmacology. vol 25. issue 5. 1986-09-16. PMID:3488514. |
the behavioural effects of haloperidol (0.2-0.4 mg/kg) and sch 23390 (0.05 mg/kg) were indistinguishable; both drugs caused sedation and inhibited all forms of motor activity. |
1986-09-16 |
2023-08-11 |
mouse |
| A Vaccheri, R Dall'Olio, O Gandolfi, N Montanar. Involvement of different dopamine receptors in rat diphasic motility response to apomorphine. Psychopharmacology. vol 89. issue 3. 1986-08-21. PMID:2873607. |
(-)-sulpiride and sultopride preferentially antagonized apomorphine inhibition; haloperidol and tiapride antagonized both phases of apomorphine response at similar doses; chlorpromazine, fluphenazine, thioridazine, metoclopramide and sch 23390 preferentially antagonized apomorphine stimulation. |
1986-08-21 |
2023-08-11 |
rat |