| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| William J Berglind, Timothy W Whitfield, Ryan T LaLumiere, Peter W Kalivas, Jacqueline F McGint. A single intra-PFC infusion of BDNF prevents cocaine-induced alterations in extracellular glutamate within the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 12. 2009-04-21. PMID:19321768. |
in the present study, it is demonstrated that a single intra-dmpfc infusion of bdnf prevents cocaine self-administration-induced reduction in basal extracellular glutamate, as well as cocaine prime-induced increases in extracellular glutamate levels within the nac. |
2009-04-21 |
2023-08-12 |
Not clear |
| Roy A Wis. Ventral tegmental glutamate: a role in stress-, cue-, and cocaine-induced reinstatement of cocaine-seeking. Neuropharmacology. vol 56 Suppl 1. 2009-04-15. PMID:18598707. |
glutamatergic input to the ventral tegmental area contributes to this activation: in animals trained to self-administer cocaine, cocaine-predictive cues trigger ventral tegmental glutamate release and dopaminergic activation. |
2009-04-15 |
2023-08-12 |
Not clear |
| Roy A Wis. Ventral tegmental glutamate: a role in stress-, cue-, and cocaine-induced reinstatement of cocaine-seeking. Neuropharmacology. vol 56 Suppl 1. 2009-04-15. PMID:18598707. |
the ability of cocaine-predictive and stress-associated cues to activate the dopamine system and to trigger cocaine craving appears to be related to changes in the ability of glutamate to activate dopaminergic neurons, changes known to be caused by experience with stress or with drugs of abuse. |
2009-04-15 |
2023-08-12 |
Not clear |
| Christopher L Nelson, Michael Milovanovic, Joseph B Wetter, Kerstin A Ford, Marina E Wol. Behavioral sensitization to amphetamine is not accompanied by changes in glutamate receptor surface expression in the rat nucleus accumbens. Journal of neurochemistry. vol 109. issue 1. 2009-04-13. PMID:19183251. |
our results suggest that glutamate transmission in the nac is dramatically different in rats sensitized to amphetamine versus cocaine. |
2009-04-13 |
2023-08-12 |
rat |
| Hao-wei Shen, Shigenobu Toda, Khaled Moussawi, Ashley Bouknight, Daniel S Zahm, Peter W Kaliva. Altered dendritic spine plasticity in cocaine-withdrawn rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 9. 2009-04-10. PMID:19261883. |
the time-dependent profile of proteins in the postsynaptic density subfraction elicited by a cocaine challenge in daily cocaine-pretreated subjects indicated that the changes in spine diameter and density were associated with a deteriorating actin cytoskeleton and a reduction in glutamate signaling-related proteins. |
2009-04-10 |
2023-08-12 |
human |
| Dhanrajan M Tiruchinapalli, Marc G Caron, Jack D Keen. Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain. Journal of neurochemistry. vol 107. issue 6. 2009-04-09. PMID:19014379. |
growing evidence indicates that both seizure (glutamate) and cocaine (dopamine) treatment modulate synaptic plasticity within the mesolimbic region of the cns. |
2009-04-09 |
2023-08-12 |
mouse |
| Jeffery H Penzner, Daria L Thompson, Cory Arth, Jaclyn K Fowler, Alexis W Ary, Karen K Szumlinsk. Protracted 'anti-addictive' effects of adolescent phenylpropanolamine exposure in C57BL/6J mice. Addiction biology. vol 13. issue 3-4. 2009-03-05. PMID:18331369. |
these data provide evidence that adolescent exposure to a formerly prevalent otc sympathomimetic produces protracted effects upon cocaine-induced changes in nac glutamate transmission that may reduce vulnerability to cocaine addiction in later life and further the hypothesis that early exposure to sympathomimetic drugs may be an environmental factor contributing to the etiology of addiction. |
2009-03-05 |
2023-08-12 |
mouse |
| Joachim D Uys, Ryan T LaLumier. Glutamate: the new frontier in pharmacotherapy for cocaine addiction. CNS & neurological disorders drug targets. vol 7. issue 5. 2009-03-05. PMID:19128205. |
glutamate: the new frontier in pharmacotherapy for cocaine addiction. |
2009-03-05 |
2023-08-12 |
Not clear |
| Joachim D Uys, Ryan T LaLumier. Glutamate: the new frontier in pharmacotherapy for cocaine addiction. CNS & neurological disorders drug targets. vol 7. issue 5. 2009-03-05. PMID:19128205. |
considerable research into the neurobiology of cocaine addiction has shed light on the role of glutamate. |
2009-03-05 |
2023-08-12 |
Not clear |
| Joachim D Uys, Ryan T LaLumier. Glutamate: the new frontier in pharmacotherapy for cocaine addiction. CNS & neurological disorders drug targets. vol 7. issue 5. 2009-03-05. PMID:19128205. |
the cysteine pro-drug, n-acetylcysteine, restores the inhibitory tone on presynaptic glutamate receptors and has been effective in reducing cue-induced craving and cocaine use in humans. |
2009-03-05 |
2023-08-12 |
Not clear |
| Johanna Schumann, Avner Michaeli, Rami Yak. Src-protein tyrosine kinases are required for cocaine-induced increase in the expression and function of the NMDA receptor in the ventral tegmental area. Journal of neurochemistry. vol 108. issue 3. 2009-02-24. PMID:19046409. |
in particular, the activation of ionotrophic glutamate nmda receptor (nmdar) in the vta is critical for the initiation of cocaine sensitization. |
2009-02-24 |
2023-08-12 |
rat |
| Hyung Shin Yoon, Ju Kyong Jang, Jeong-Hoon Ki. Blockade of group II metabotropic glutamate receptors produces hyper-locomotion in cocaine pre-exposed rats by interactions with dopamine receptors. Neuropharmacology. vol 55. issue 4. 2009-02-06. PMID:18675831. |
blockade of group ii metabotropic glutamate receptors produces hyper-locomotion in cocaine pre-exposed rats by interactions with dopamine receptors. |
2009-02-06 |
2023-08-12 |
rat |
| Alejandra M Pacchioni, Joseph Vallone, Paul F Worley, Peter W Kaliva. Neuronal pentraxins modulate cocaine-induced neuroadaptations. The Journal of pharmacology and experimental therapeutics. vol 328. issue 1. 2009-02-03. PMID:18840757. |
consistent with reduced ampa responsiveness after chronic cocaine in narp ko mice, glutamate receptor 1 was reduced in the psd fraction of narp ko mice withdrawn from cocaine. |
2009-02-03 |
2023-08-12 |
mouse |
| Ryan K Bachtell, David W Sel. Renewed cocaine exposure produces transient alterations in nucleus accumbens AMPA receptor-mediated behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 48. 2009-01-26. PMID:19036973. |
reversal in ampar sensitivity was prohibited by nac ampar blockade with cnqx during cocaine reexposure and mimicked by intra-nac infusions of ampa, suggesting that cocaine-induced glutamate stimulation of nac ampars is necessary for reversing ampar responsiveness. |
2009-01-26 |
2023-08-12 |
Not clear |
| Ryan K Bachtell, David W Sel. Renewed cocaine exposure produces transient alterations in nucleus accumbens AMPA receptor-mediated behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 48. 2009-01-26. PMID:19036973. |
similarly, systemic treatment with the dopamine d(1)-like agonist skf 81297 [(+/-)-6-chloro-7,8-dihydroxy-l-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine hydrobromide] reversed ampar responsiveness in cocaine withdrawal, but the effect was prevented by local nac ampar blockade in the nac, and not local d(1)-like receptor blockade, suggesting a role for glutamate afferents in the reversal of enhanced ampar sensitivity. |
2009-01-26 |
2023-08-12 |
Not clear |
| Ryan K Bachtell, David W Sel. Renewed cocaine exposure produces transient alterations in nucleus accumbens AMPA receptor-mediated behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 48. 2009-01-26. PMID:19036973. |
together, these findings suggest that cocaine-induced glutamate release in sensitized animals is responsible for dynamic alterations in ampar function that contribute to enhanced cocaine sensitivity. |
2009-01-26 |
2023-08-12 |
Not clear |
| Wei-Lun Sun, Luyi Zhou, Ruhal Hazim, Vanya Quinones-Jenab, Shirzad Jena. Effects of dopamine and NMDA receptors on cocaine-induced Fos expression in the striatum of Fischer rats. Brain research. vol 1243. 2009-01-21. PMID:18822274. |
cocaine is an addictive psychostimulant that induces immediate early gene (ieg) expression by activating dopamine (da) d1 and glutamate nmda receptors in the striatum. |
2009-01-21 |
2023-08-12 |
rat |
| Miguel Miguéns, José Antonio Crespo, Nuria Del Olmo, Alejandro Higuera-Matas, Gonzalo L Montoya, Carmen García-Lecumberri, Emilio Ambrosi. Differential cocaine-induced modulation of glutamate and dopamine transporters after contingent and non-contingent administration. Neuropharmacology. vol 55. issue 5. 2009-01-15. PMID:18634806. |
although dopamine and glutamate transmission has been implicated in cocaine dependence, the effects of the extinction of cocaine self-administration on protein transporters in both of these neurotransmitter systems remain unknown. |
2009-01-15 |
2023-08-12 |
rat |
| Roy A Wise, Bin Wang, Zhi-Bing Yo. Cocaine serves as a peripheral interoceptive conditioned stimulus for central glutamate and dopamine release. PloS one. vol 3. issue 8. 2008-12-18. PMID:18682722. |
cocaine serves as a peripheral interoceptive conditioned stimulus for central glutamate and dopamine release. |
2008-12-18 |
2023-08-12 |
rat |
| Roy A Wise, Bin Wang, Zhi-Bing Yo. Cocaine serves as a peripheral interoceptive conditioned stimulus for central glutamate and dopamine release. PloS one. vol 3. issue 8. 2008-12-18. PMID:18682722. |
to explore the contribution of peripheral effects of cocaine to the early activation of the dopamine system, we used brain microdialysis to measure the effects of cocaine methiodide (mi)--a cocaine analogue that does not cross the blood brain barrier--on glutamate (excitatory) input to the dopamine cells. |
2008-12-18 |
2023-08-12 |
rat |