| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Roy A Wise, Bin Wang, Zhi-Bing Yo. Cocaine serves as a peripheral interoceptive conditioned stimulus for central glutamate and dopamine release. PloS one. vol 3. issue 8. 2008-12-18. PMID:18682722. |
ip injections of cocaine mi were ineffective in cocaine-naïve animals but stimulated ventral tegmental glutamate release in rats previously trained to lever-press for cocaine hcl. |
2008-12-18 |
2023-08-12 |
rat |
| Florence Nobl. [Current preclinical knowledge of the neurobiology of cocaine]. Presse medicale (Paris, France : 1983). vol 37. issue 12. 2008-12-18. PMID:18768291. |
cocaine controls many neurotransmitter systems, including glutamate, gaba, dopamine, serotonin, and noradrenalin. |
2008-12-18 |
2023-08-12 |
Not clear |
| K S Kau, A Madayag, J R Mantsch, M D Grier, O Abdulhameed, D A Bake. Blunted cystine-glutamate antiporter function in the nucleus accumbens promotes cocaine-induced drug seeking. Neuroscience. vol 155. issue 2. 2008-12-03. PMID:18601982. |
repeated cocaine alters glutamate neurotransmission, in part, by reducing cystine-glutamate exchange via system xc-, which maintains glutamate levels and receptor stimulation in the extrasynaptic compartment. |
2008-12-03 |
2023-08-12 |
rat |
| Katie R Famous, Vidhya Kumaresan, Ghazaleh Sadri-Vakili, Heath D Schmidt, Dale F Mierke, Jang-Ho J Cha, R Christopher Pierc. Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 43. 2008-12-01. PMID:18945913. |
a growing body of evidence indicates that enhanced ampa-mediated glutamate transmission in the core of the nucleus accumbens is critically involved in cocaine priming-induced reinstatement of drug seeking, an animal model of relapse. |
2008-12-01 |
2023-08-12 |
Not clear |
| Katie R Famous, Vidhya Kumaresan, Ghazaleh Sadri-Vakili, Heath D Schmidt, Dale F Mierke, Jang-Ho J Cha, R Christopher Pierc. Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 43. 2008-12-01. PMID:18945913. |
however, the extent to which increased glutamate transmission in the other major subregion of the nucleus accumbens, the shell, contributes to the reinstatement of cocaine seeking remains unclear. |
2008-12-01 |
2023-08-12 |
Not clear |
| Katie R Famous, Vidhya Kumaresan, Ghazaleh Sadri-Vakili, Heath D Schmidt, Dale F Mierke, Jang-Ho J Cha, R Christopher Pierc. Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 43. 2008-12-01. PMID:18945913. |
together, these findings indicate that changes in ampa receptor-mediated glutamate transmission in both the nucleus accumbens core and shell are necessary for the reinstatement of drug seeking induced by a priming injection of cocaine. |
2008-12-01 |
2023-08-12 |
Not clear |
| Arturo R Zavala, Jenny R Browning, Erin D Dickey, Sudipta Biswas, Janet L Neisewande. Region-specific involvement of AMPA/Kainate receptors in Fos protein expression induced by cocaine-conditioned cues. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 8. 2008-11-05. PMID:18539009. |
nbqx markedly attenuated cue-elicited cocaine-seeking behavior relative to vehicle pretreatment in the no extinction group and also decreased cue-elicited fos protein expression in a region-specific manner in the anterior cingulate and orbitofrontal cortices, basolateral amygdala, nucleus accumbens core, and dorsal caudate-putamen, suggesting involvement of ampa glutamate systems in specific subregions of the neuronal circuitry activated by cocaine cues. |
2008-11-05 |
2023-08-12 |
rat |
| Xiaohu Xie, Jeffery D Stekete. Repeated exposure to cocaine alters the modulation of mesocorticolimbic glutamate transmission by medial prefrontal cortex Group II metabotropic glutamate receptors. Journal of neurochemistry. vol 107. issue 1. 2008-11-03. PMID:18673447. |
repeated exposure to cocaine alters the modulation of mesocorticolimbic glutamate transmission by medial prefrontal cortex group ii metabotropic glutamate receptors. |
2008-11-03 |
2023-08-12 |
Not clear |
| Xiaohu Xie, Jeffery D Stekete. Repeated exposure to cocaine alters the modulation of mesocorticolimbic glutamate transmission by medial prefrontal cortex Group II metabotropic glutamate receptors. Journal of neurochemistry. vol 107. issue 1. 2008-11-03. PMID:18673447. |
recent research indicated that repeated cocaine exposure reduced the ability of cortical group ii metabotropic glutamate receptors to modulate behavioral and neurochemical responses to cocaine. |
2008-11-03 |
2023-08-12 |
Not clear |
| Xiaohu Xie, Jeffery D Stekete. Repeated exposure to cocaine alters the modulation of mesocorticolimbic glutamate transmission by medial prefrontal cortex Group II metabotropic glutamate receptors. Journal of neurochemistry. vol 107. issue 1. 2008-11-03. PMID:18673447. |
thus, experiments described below examined whether repeated cocaine exposure alters metabotropic glutamate receptor regulation of mesocorticolimbic glutamatergic transmission using in vivo microdialysis. |
2008-11-03 |
2023-08-12 |
Not clear |
| Xiaohu Xie, Jeffery D Stekete. Repeated exposure to cocaine alters the modulation of mesocorticolimbic glutamate transmission by medial prefrontal cortex Group II metabotropic glutamate receptors. Journal of neurochemistry. vol 107. issue 1. 2008-11-03. PMID:18673447. |
in summary, these findings indicate that the expression of sensitization to cocaine is correlated with an altered modulation of mesocorticolimbic glutamatergic transmission via reduction of group ii metabotropic glutamate receptor function. |
2008-11-03 |
2023-08-12 |
Not clear |
| Dong Kun Lee, Shengjie Bian, Md Aminur Rahman, Yoon-Bo Shim, Insop Shim, Eun Sang Cho. Repeated cocaine administration increases N-methyl-d-aspartate NR1 subunit, extracellular signal-regulated kinase and cyclic AMP response element-binding protein phosphorylation and glutamate release in the rat dorsal striatum. European journal of pharmacology. vol 590. issue 1-3. 2008-10-14. PMID:18598691. |
repeated cocaine administration increases n-methyl-d-aspartate nr1 subunit, extracellular signal-regulated kinase and cyclic amp response element-binding protein phosphorylation and glutamate release in the rat dorsal striatum. |
2008-10-14 |
2023-08-12 |
rat |
| Dong Kun Lee, Shengjie Bian, Md Aminur Rahman, Yoon-Bo Shim, Insop Shim, Eun Sang Cho. Repeated cocaine administration increases N-methyl-d-aspartate NR1 subunit, extracellular signal-regulated kinase and cyclic AMP response element-binding protein phosphorylation and glutamate release in the rat dorsal striatum. European journal of pharmacology. vol 590. issue 1-3. 2008-10-14. PMID:18598691. |
the real-time changes of glutamate concentration evoked by repeated cocaine injections were examined using a glutamate biosensor in order to evaluate the correlation between glutamate concentration and the change in these phosphoproteins. |
2008-10-14 |
2023-08-12 |
rat |
| Dong Kun Lee, Shengjie Bian, Md Aminur Rahman, Yoon-Bo Shim, Insop Shim, Eun Sang Cho. Repeated cocaine administration increases N-methyl-d-aspartate NR1 subunit, extracellular signal-regulated kinase and cyclic AMP response element-binding protein phosphorylation and glutamate release in the rat dorsal striatum. European journal of pharmacology. vol 590. issue 1-3. 2008-10-14. PMID:18598691. |
similarly, glutamate responses evoked by repeated cocaine injections were also increased 30 min after repeated cocaine injections for 3 days and were prolonged by the 9th day of treatment. |
2008-10-14 |
2023-08-12 |
rat |
| Dong Kun Lee, Shengjie Bian, Md Aminur Rahman, Yoon-Bo Shim, Insop Shim, Eun Sang Cho. Repeated cocaine administration increases N-methyl-d-aspartate NR1 subunit, extracellular signal-regulated kinase and cyclic AMP response element-binding protein phosphorylation and glutamate release in the rat dorsal striatum. European journal of pharmacology. vol 590. issue 1-3. 2008-10-14. PMID:18598691. |
however, the glutamate responses were not detected at 4 h after repeated cocaine injections for 5 days. |
2008-10-14 |
2023-08-12 |
rat |
| Dong Kun Lee, Shengjie Bian, Md Aminur Rahman, Yoon-Bo Shim, Insop Shim, Eun Sang Cho. Repeated cocaine administration increases N-methyl-d-aspartate NR1 subunit, extracellular signal-regulated kinase and cyclic AMP response element-binding protein phosphorylation and glutamate release in the rat dorsal striatum. European journal of pharmacology. vol 590. issue 1-3. 2008-10-14. PMID:18598691. |
these findings suggest that glutamate release and dopamine d1 and nmda receptor stimulation after repeated exposure to cocaine are associated with nmda nr1 subunit, erk1/2 and creb phosphorylation in the dorsal striatum. |
2008-10-14 |
2023-08-12 |
rat |
| David Engblom, Ainhoa Bilbao, Carles Sanchis-Segura, Lionel Dahan, Stéphanie Perreau-Lenz, Bénédicte Balland, Jan Rodriguez Parkitna, Rafael Luján, Briac Halbout, Manuel Mameli, Rosanna Parlato, Rolf Sprengel, Christian Lüscher, Günther Schütz, Rainer Spanage. Glutamate receptors on dopamine neurons control the persistence of cocaine seeking. Neuron. vol 59. issue 3. 2008-09-17. PMID:18701074. |
glutamate receptors on dopamine neurons control the persistence of cocaine seeking. |
2008-09-17 |
2023-08-12 |
mouse |
| C R Ferrario, M Shou, A N Samaha, C J Watson, R T Kennedy, T E Robinso. The rate of intravenous cocaine administration alters c-fos mRNA expression and the temporal dynamics of dopamine, but not glutamate, overflow in the striatum. Brain research. vol 1209. 2008-08-11. PMID:18396266. |
the rate of intravenous cocaine administration alters c-fos mrna expression and the temporal dynamics of dopamine, but not glutamate, overflow in the striatum. |
2008-08-11 |
2023-08-12 |
rat |
| C R Ferrario, M Shou, A N Samaha, C J Watson, R T Kennedy, T E Robinso. The rate of intravenous cocaine administration alters c-fos mRNA expression and the temporal dynamics of dopamine, but not glutamate, overflow in the striatum. Brain research. vol 1209. 2008-08-11. PMID:18396266. |
we hypothesized, therefore, that varying the rate of intravenous cocaine delivery might influence dopamine and/or glutamate overflow in the striatum. |
2008-08-11 |
2023-08-12 |
rat |
| C R Ferrario, M Shou, A N Samaha, C J Watson, R T Kennedy, T E Robinso. The rate of intravenous cocaine administration alters c-fos mRNA expression and the temporal dynamics of dopamine, but not glutamate, overflow in the striatum. Brain research. vol 1209. 2008-08-11. PMID:18396266. |
to test this we used microdialysis coupled to on-line capillary electrophoresis and laser-induced fluorescence, which allows for very rapid sampling, to compare the effects of a rapid (5 s) versus a slow (100 s) intravenous cocaine infusion on extracellular dopamine and glutamate levels in the striatum of freely moving rats. |
2008-08-11 |
2023-08-12 |
rat |