| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marta Pardo, Michele Martin, Raul R Gainetdinov, Deborah C Mash, Sari Izenwasse. Heterozygote Dopamine Transporter Knockout Rats Display Enhanced Cocaine Locomotion in Adolescent Females. International journal of molecular sciences. vol 23. issue 23. 2022-12-11. PMID:36499749. |
the dopamine transporter (dat) plays a major role in mediating cocaine's reward effect. |
2022-12-11 |
2023-08-14 |
rat |
| Michał Wilczkowski, Karolina Karwowska, Michal Kielbinski, Katarzyna Zajda, Kamil Pradel, Gniewosz Drwięga, Zenon Rajfur, Tomasz Blasiak, Ryszard Przewlocki, Wojciech B Soleck. Recruitment of inhibitory neuronal pathways regulating dopaminergic activity for the control of cocaine seeking. The European journal of neuroscience. 2022-12-08. PMID:36479859. |
keywords: cocaine seeking; ventral tegmental area; dopamine; rostromedial tegmental nucleus; lateral habenula. |
2022-12-08 |
2023-08-14 |
rat |
| Emmanuel Darcq, Dominique Nouel, Giovanni Hernandez, Matthew Pokinko, Polina Ash, Luc Moquin, Alain Gratton, Brigitte Kieffer, Cecilia Flore. Reduced dopamine release in Dcc haploinsufficiency male mice abolishes the rewarding effects of cocaine but not those of morphine and ethanol. Psychopharmacology. 2022-12-05. PMID:36471064. |
reduced dopamine release in dcc haploinsufficiency male mice abolishes the rewarding effects of cocaine but not those of morphine and ethanol. |
2022-12-05 |
2023-08-14 |
mouse |
| Kevin T Ball, Hunter Edso. Chronic restraint stress increases sensitivity to punishment during cocaine self-administration via a dopamine D Neuroscience letters. 2022-12-01. PMID:36455694. |
chronic restraint stress increases sensitivity to punishment during cocaine self-administration via a dopamine d we recently reported that male rats displayed less sensitivity to punishment during cocaine self-administration compared to females. |
2022-12-01 |
2023-08-14 |
rat |
| Kevin T Ball, Hunter Edso. Chronic restraint stress increases sensitivity to punishment during cocaine self-administration via a dopamine D Neuroscience letters. 2022-12-01. PMID:36455694. |
the purpose of the present study was to extend these findings by determining whether chronic stress-induced dopamine release in prelimbic medial prefrontal cortex mediates the effect of stress on punished cocaine self-administration. |
2022-12-01 |
2023-08-14 |
rat |
| Sarah E Swinford-Jackson, Phillip J Huffman, Melissa C Knouse, Arthur S Thomas, Matthew T Rich, Sharvari Mankame, Samantha J Worobey, Mateo Sarmiento, Ayanna Coleman, R Christopher Pierc. High frequency DBS-like optogenetic stimulation of nucleus accumbens dopamine D2 receptor-containing neurons attenuates cocaine reinstatement in male rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-11-29. PMID:36446928. |
high frequency dbs-like optogenetic stimulation of nucleus accumbens dopamine d2 receptor-containing neurons attenuates cocaine reinstatement in male rats. |
2022-11-29 |
2023-08-14 |
rat |
| Andrés Angel Calderon-Garcia, Maria Perez-Fernandez, Daniel Curto-Aguilera, Ivan Rodriguez-Martin, Mercedes Sánchez-Barba, Veronica Gonzalez-Nune. Exposure to Morphine and Cocaine Modify the Transcriptomic Landscape in Zebrafish Embryos. Neuroscience. 2022-11-21. PMID:36404518. |
cocaine is a potent inhibitor of dopamine, serotonin, and noradrenaline reuptake, as it blocks dat, the dopamine transporter, causing an increase in the local concentration of these neurotransmitters in the synaptic cleft. |
2022-11-21 |
2023-08-14 |
zebrafish |
| Laísa Aliandro Dos Santos, Gabriela Salles Dos Santos, Gustavo Ariel Borges Fernandes, Michelle Fidelis Corrêa, Carolina Aparecida de Faria Almeida, Liliam Fernandes, Tania Marcourakis, João Paulo S Fernandes, Raphael Caio Tamborelli Garci. Neurotoxicity Assessment of 1-[(2,3-Dihydro-1-Benzofuran-2-yl)Methyl]Piperazine (LINS01 Series) Derivatives and their Protective Effect on Cocaine-Induced Neurotoxicity Model in SH-SY5Y Cell Culture. Neurotoxicity research. 2022-11-07. PMID:36342586. |
excessive levels of dopamine in the synaptic cleft, induced by cocaine for example, activates dopaminergic receptors, mainly d |
2022-11-07 |
2023-08-14 |
Not clear |
| Jing Deng, Xirong Zheng, Linyue Shang, Chang-Guo Zhan, Fang Zhen. Gender differences in cocaine-induced hyperactivity and dopamine transporter trafficking to the plasma membrane. Addiction biology. vol 27. issue 6. 2022-10-27. PMID:36301205. |
as well known, cocaine induces stimulant effects and dopamine transporter (dat) trafficking to the plasma membrane of dopaminergic neurons. |
2022-10-27 |
2023-08-14 |
rat |
| Juan Li, Yue Wu, Tao Xue, Jing He, Lei Zhang, Yutong Liu, Jinlan Zhao, Zhenzhong Chen, Minjuan Xie, Bin Xiao, Yingshan Ye, Sifei Qin, Qingqiu Tang, Mengfan Huang, Hangfei Zhu, N Liu, Fukun Guo, Lin Zhang, Lu Zhan. Cdc42 signaling regulated by dopamine D2 receptor correlatively links specific brain regions of hippocampus to cocaine addiction. Biochimica et biophysica acta. Molecular basis of disease. 2022-10-15. PMID:36243293. |
cdc42 signaling regulated by dopamine d2 receptor correlatively links specific brain regions of hippocampus to cocaine addiction. |
2022-10-15 |
2023-08-14 |
Not clear |
| Antony D Abraham, Sanne M Casello, Benjamin B Land, Charles Chavki. Optogenetic stimulation of dynorphinergic neurons within the dorsal raphe activate kappa opioid receptors in the ventral tegmental area and ablation of dorsal raphe prodynorphin or kappa receptors in dopamine neurons blocks stress potentiation of cocaine reward. Addiction neuroscience. vol 1. 2022-09-30. PMID:36176476. |
optogenetic stimulation of dynorphinergic neurons within the dorsal raphe activate kappa opioid receptors in the ventral tegmental area and ablation of dorsal raphe prodynorphin or kappa receptors in dopamine neurons blocks stress potentiation of cocaine reward. |
2022-09-30 |
2023-08-14 |
mouse |
| Antony D Abraham, Sanne M Casello, Benjamin B Land, Charles Chavki. Optogenetic stimulation of dynorphinergic neurons within the dorsal raphe activate kappa opioid receptors in the ventral tegmental area and ablation of dorsal raphe prodynorphin or kappa receptors in dopamine neurons blocks stress potentiation of cocaine reward. Addiction neuroscience. vol 1. 2022-09-30. PMID:36176476. |
genetic ablation of kors from dopamine neurons blocked the potentiating effects of repeated forced swim stress on cocaine conditioned place preference (cpp). |
2022-09-30 |
2023-08-14 |
mouse |
| Antony D Abraham, Sanne M Casello, Benjamin B Land, Charles Chavki. Optogenetic stimulation of dynorphinergic neurons within the dorsal raphe activate kappa opioid receptors in the ventral tegmental area and ablation of dorsal raphe prodynorphin or kappa receptors in dopamine neurons blocks stress potentiation of cocaine reward. Addiction neuroscience. vol 1. 2022-09-30. PMID:36176476. |
transient optogenetic inhibition of vta dopamine neurons with aav5-dio-swichr was acutely aversive in a real time place preference assay and blunted cocaine cpp when inhibition was administered concurrently with cocaine conditioning. |
2022-09-30 |
2023-08-14 |
mouse |
| Kathy Z Dai, In Bae Choi, Ryan Levitt, Mariah B Blegen, Alanna R Kaplan, Aya Matsui, J Hoon Shin, Miriam E Bocarsly, Eleanor H Simpson, Christoph Kellendonk, Veronica A Alvarez, Lauren K Dobb. Dopamine D2 receptors bidirectionally regulate striatal enkephalin expression: Implications for cocaine reward. Cell reports. vol 40. issue 13. 2022-09-28. PMID:36170833. |
dopamine d2 receptors bidirectionally regulate striatal enkephalin expression: implications for cocaine reward. |
2022-09-28 |
2023-08-14 |
mouse |
| Kathy Z Dai, In Bae Choi, Ryan Levitt, Mariah B Blegen, Alanna R Kaplan, Aya Matsui, J Hoon Shin, Miriam E Bocarsly, Eleanor H Simpson, Christoph Kellendonk, Veronica A Alvarez, Lauren K Dobb. Dopamine D2 receptors bidirectionally regulate striatal enkephalin expression: Implications for cocaine reward. Cell reports. vol 40. issue 13. 2022-09-28. PMID:36170833. |
low dopamine d2 receptor (d2r) availability in the striatum can predispose for cocaine abuse; though how low striatal d2rs facilitate cocaine reward is unclear. |
2022-09-28 |
2023-08-14 |
mouse |
| Jun Zhu, Pamela M Quizon, Yingying Wang, Charles A Adeniran, Matthew J Strauss, Ana Jimenez Torres, Palak Patel, Thomas J Cirino, Shainnel O Eans, Haylee R Hammond, Laure S Deliscar, Priscilla O'Hara, Surendra K Saini, Edward Ofori, Rakesh H Vekariya, Sixue Zhang, Omar Moukha-Chafiq, Theresa Nguyen, Subramaniam Ananthan, Corinne E Augelli-Szafran, Chang-Guo Zhan, Jay P McLaughli. SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-induced inhibition of dopamine transporter and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice. Neuropharmacology. 2022-09-20. PMID:36126727. |
sri-32743, a novel allosteric modulator, attenuates hiv-1 tat protein-induced inhibition of dopamine transporter and alleviates the potentiation of cocaine reward in hiv-1 tat transgenic mice. |
2022-09-20 |
2023-08-14 |
mouse |
| María P Avalos, Andrea S Guzman, Constanza Garcia-Keller, Bethania Mongi-Bragato, María A Esparza, Daiana Rigoni, Marianela A Sanchez, Gastón D Calfa, Flavia A Bollati, Liliana M Cancel. Impairment of glutamate homeostasis in the nucleus accumbens core underpins cross-sensitization to cocaine following chronic restraint stress. Frontiers in physiology. vol 13. 2022-09-12. PMID:36091376. |
our results demonstrated that the enduring crs-induced increase in psychostimulant response to cocaine was paralleled by an increase of extracellular dopamine levels in the nacore, but not the nashell, greater than that observed in the non-stress group. |
2022-09-12 |
2023-08-14 |
rat |
| I Pamela Alonso, Bethan M O'Connor, Kathleen G Bryant, Rushi K Mandalaywala, Rodrigo A Españ. Incubation of cocaine craving coincides with changes in dopamine terminal neurotransmission. Addiction neuroscience. vol 3. 2022-09-09. PMID:36081573. |
incubation of cocaine craving coincides with changes in dopamine terminal neurotransmission. |
2022-09-09 |
2023-08-14 |
rat |
| I Pamela Alonso, Bethan M O'Connor, Kathleen G Bryant, Rushi K Mandalaywala, Rodrigo A Españ. Incubation of cocaine craving coincides with changes in dopamine terminal neurotransmission. Addiction neuroscience. vol 3. 2022-09-09. PMID:36081573. |
although the neurobiology underlying incubation of cocaine craving has been examined - particularly within the context of glutamate plasticity- the extent to which increased cocaine craving engenders mesolimbic dopamine (da) changes has received relatively little attention. |
2022-09-09 |
2023-08-14 |
rat |
| Megan A McWain, Rachel L Pace, Patricia A Nalan, Deranda B Leste. Age-dependent effects of social isolation on mesolimbic dopamine release. Experimental brain research. 2022-09-03. PMID:36057752. |
mice were socially isolated for 6 weeks during these developmental stages, then in vivo fixed potential amperometry with recording electrodes in the nucleus accumbens was used to measure stimulation-evoked dopamine release, the synaptic half-life of dopamine, dopamine autoreceptor functioning, and the dopaminergic response to cocaine. |
2022-09-03 |
2023-08-14 |
mouse |