| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jason Yuen, Abhinav Goyal, Aaron E Rusheen, Abbas Z Kouzani, Michael Berk, Jee Hyun Kim, Susannah J Tye, Charles D Blaha, Kevin E Bennet, Kendall H Lee, Hojin Shin, Yoonbae O. High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens. Frontiers in neuroscience. vol 17. 2023-02-16. PMID:36793536. |
high frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens. |
2023-02-16 |
2023-08-14 |
rat |
| Jason Yuen, Abhinav Goyal, Aaron E Rusheen, Abbas Z Kouzani, Michael Berk, Jee Hyun Kim, Susannah J Tye, Charles D Blaha, Kevin E Bennet, Kendall H Lee, Hojin Shin, Yoonbae O. High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens. Frontiers in neuroscience. vol 17. 2023-02-16. PMID:36793536. |
cocaine's addictive properties stem from its capacity to increase tonic extracellular dopamine levels in the nucleus accumbens (nac). |
2023-02-16 |
2023-08-14 |
rat |
| Jason Yuen, Abhinav Goyal, Aaron E Rusheen, Abbas Z Kouzani, Michael Berk, Jee Hyun Kim, Susannah J Tye, Charles D Blaha, Kevin E Bennet, Kendall H Lee, Hojin Shin, Yoonbae O. High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens. Frontiers in neuroscience. vol 17. 2023-02-16. PMID:36793536. |
to investigate how high frequency stimulation (hfs) of the rodent vta or nucleus accumbens core (nacc) modulates the acute effects of cocaine administration on nacc tonic dopamine levels multiple-cyclic square wave voltammetry (m-cswv) was used. |
2023-02-16 |
2023-08-14 |
rat |
| Jason Yuen, Abhinav Goyal, Aaron E Rusheen, Abbas Z Kouzani, Michael Berk, Jee Hyun Kim, Susannah J Tye, Charles D Blaha, Kevin E Bennet, Kendall H Lee, Hojin Shin, Yoonbae O. High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens. Frontiers in neuroscience. vol 17. 2023-02-16. PMID:36793536. |
vta or nacc hfs following cocaine administration prevented the cocaine-induced increase in nacc tonic dopamine. |
2023-02-16 |
2023-08-14 |
rat |
| Jason Yuen, Abhinav Goyal, Aaron E Rusheen, Abbas Z Kouzani, Michael Berk, Jee Hyun Kim, Susannah J Tye, Charles D Blaha, Kevin E Bennet, Kendall H Lee, Hojin Shin, Yoonbae O. High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens. Frontiers in neuroscience. vol 17. 2023-02-16. PMID:36793536. |
the present results suggest a possible underlying mechanism of nac deep brain stimulation (dbs) in the treatment of substance use disorders (suds) and the possibility of treating sud by abolishing dopamine release elicited by cocaine and other drugs of abuse by dbs in vta, although further studies with chronic addiction models are required to confirm that. |
2023-02-16 |
2023-08-14 |
rat |
| Sarah E Swinford-Jackson, Matthew T Rich, Phillip J Huffman, Melissa C Knouse, Arthur S Thomas, Sharvari Mankame, Samantha J Worobey, R Christopher Pierc. Low frequency optogenetic deep brain stimulation of nucleus accumbens dopamine D1 or D2 receptor-containing neurons attenuates cocaine seeking selectively in male rats in part by reversing synaptic plasticity deficits. bioRxiv : the preprint server for biology. 2023-02-07. PMID:36747662. |
low frequency optogenetic deep brain stimulation of nucleus accumbens dopamine d1 or d2 receptor-containing neurons attenuates cocaine seeking selectively in male rats in part by reversing synaptic plasticity deficits. |
2023-02-07 |
2023-08-14 |
rat |
| Paige M Estave, Haiguo Sun, Emily G Peck, Katherine M Holleran, Rong Chen, Sara R Jone. Cocaine self-administration augments kappa opioid receptor system-mediated inhibition of dopamine activity in the mesolimbic dopamine system. IBRO neuroscience reports. vol 14. 2023-02-07. PMID:36748012. |
cocaine self-administration augments kappa opioid receptor system-mediated inhibition of dopamine activity in the mesolimbic dopamine system. |
2023-02-07 |
2023-08-14 |
human |
| Paige M Estave, Haiguo Sun, Emily G Peck, Katherine M Holleran, Rong Chen, Sara R Jone. Cocaine self-administration augments kappa opioid receptor system-mediated inhibition of dopamine activity in the mesolimbic dopamine system. IBRO neuroscience reports. vol 14. 2023-02-07. PMID:36748012. |
in this study we characterized the effects of escalated intravenous cocaine self-administration on the functional state of the dyn/kor system and its interaction with mesolimbic dopamine signaling. |
2023-02-07 |
2023-08-14 |
human |
| Søren H Jørgensen, Aske L Ejdrup, Matthew D Lycas, Leonie P Posselt, Kenneth L Madsen, Lin Tian, Jakob K Dreyer, Freja Herborg, Andreas T Sørensen, Ulrik Gethe. Behavioral encoding across timescales by region-specific dopamine dynamics. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 7. 2023-02-07. PMID:36749722. |
disruption of dopamine dynamics with cocaine caused randomization of action selection sequencing and disturbance of ds-vs coordination. |
2023-02-07 |
2023-08-14 |
mouse |
| Gabriel de Farias Araujo, Renata Jurema Medeiros, Magno Maciel-Magalhães, Fábio Veríssimo Correia, Enrico Mendes Saggior. Zebrafish (Danio rerio) as a model to assess the effects of cocaine as a drug of abuse and its environmental implications. Environmental science and pollution research international. 2023-01-23. PMID:36689115. |
cocaine exposure was noted as altering the expression of several genes, such as those linked to coc transport proteins, dopamine receptors, sp substance production, the tachykinin system, and the tyrosine hydroxylase enzyme. |
2023-01-23 |
2023-08-14 |
zebrafish |
| Salin Adélie, Dugast Emilie, Lardeux Virginie, Solinas Marcello, Belujon Paulin. The amygdala-ventral pallidum pathway contributes to a hypodopaminergic state in the ventral tegmental area during protracted abstinence from chronic cocaine. British journal of pharmacology. 2023-01-16. PMID:36645812. |
decrease of dopamine (da) release and decrease in da neurons' activity (hypodopaminergic state) have been reported in the ventral tegmental area (vta) during cocaine abstinence but the mechanisms underlying these neuroadaptations are not well understood. |
2023-01-16 |
2023-08-14 |
Not clear |
| Jacqueline Saenz, Oscar Yao, Elnaz Khezerlou, Meha Aggarwal, Xiaofeng Zhou, David J Barker, Emanuel DiCicco-Bloom, Ping-Yue Pa. Cocaine-regulated trafficking of dopamine transporters in cultured neurons revealed by a pH sensitive reporter. iScience. vol 26. issue 1. 2023-01-03. PMID:36594015. |
cocaine acts by inhibiting plasma membrane dopamine transporter (dat) function and altering its surface expression. |
2023-01-03 |
2023-08-14 |
mouse |
| Shiyu Wang, Anna I Neel, Kristen L Adams, Haiguo Sun, Sara R Jones, Allyn C Howlett, Rong Che. Atorvastatin differentially regulates the interactions of cocaine and amphetamine with dopamine transporters. Neuropharmacology. 2022-12-25. PMID:36567004. |
atorvastatin differentially regulates the interactions of cocaine and amphetamine with dopamine transporters. |
2022-12-25 |
2023-08-14 |
Not clear |
| Marta Pardo, Michele Martin, Raul R Gainetdinov, Deborah C Mash, Sari Izenwasse. Heterozygote Dopamine Transporter Knockout Rats Display Enhanced Cocaine Locomotion in Adolescent Females. International journal of molecular sciences. vol 23. issue 23. 2022-12-11. PMID:36499749. |
heterozygote dopamine transporter knockout rats display enhanced cocaine locomotion in adolescent females. |
2022-12-11 |
2023-08-14 |
rat |
| Marta Pardo, Michele Martin, Raul R Gainetdinov, Deborah C Mash, Sari Izenwasse. Heterozygote Dopamine Transporter Knockout Rats Display Enhanced Cocaine Locomotion in Adolescent Females. International journal of molecular sciences. vol 23. issue 23. 2022-12-11. PMID:36499749. |
the dopamine transporter (dat) plays a major role in mediating cocaine's reward effect. |
2022-12-11 |
2023-08-14 |
rat |
| Michał Wilczkowski, Karolina Karwowska, Michal Kielbinski, Katarzyna Zajda, Kamil Pradel, Gniewosz Drwięga, Zenon Rajfur, Tomasz Blasiak, Ryszard Przewlocki, Wojciech B Soleck. Recruitment of inhibitory neuronal pathways regulating dopaminergic activity for the control of cocaine seeking. The European journal of neuroscience. 2022-12-08. PMID:36479859. |
keywords: cocaine seeking; ventral tegmental area; dopamine; rostromedial tegmental nucleus; lateral habenula. |
2022-12-08 |
2023-08-14 |
rat |
| Emmanuel Darcq, Dominique Nouel, Giovanni Hernandez, Matthew Pokinko, Polina Ash, Luc Moquin, Alain Gratton, Brigitte Kieffer, Cecilia Flore. Reduced dopamine release in Dcc haploinsufficiency male mice abolishes the rewarding effects of cocaine but not those of morphine and ethanol. Psychopharmacology. 2022-12-05. PMID:36471064. |
reduced dopamine release in dcc haploinsufficiency male mice abolishes the rewarding effects of cocaine but not those of morphine and ethanol. |
2022-12-05 |
2023-08-14 |
mouse |
| Kevin T Ball, Hunter Edso. Chronic restraint stress increases sensitivity to punishment during cocaine self-administration via a dopamine D Neuroscience letters. 2022-12-01. PMID:36455694. |
chronic restraint stress increases sensitivity to punishment during cocaine self-administration via a dopamine d we recently reported that male rats displayed less sensitivity to punishment during cocaine self-administration compared to females. |
2022-12-01 |
2023-08-14 |
rat |
| Kevin T Ball, Hunter Edso. Chronic restraint stress increases sensitivity to punishment during cocaine self-administration via a dopamine D Neuroscience letters. 2022-12-01. PMID:36455694. |
the purpose of the present study was to extend these findings by determining whether chronic stress-induced dopamine release in prelimbic medial prefrontal cortex mediates the effect of stress on punished cocaine self-administration. |
2022-12-01 |
2023-08-14 |
rat |
| Sarah E Swinford-Jackson, Phillip J Huffman, Melissa C Knouse, Arthur S Thomas, Matthew T Rich, Sharvari Mankame, Samantha J Worobey, Mateo Sarmiento, Ayanna Coleman, R Christopher Pierc. High frequency DBS-like optogenetic stimulation of nucleus accumbens dopamine D2 receptor-containing neurons attenuates cocaine reinstatement in male rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-11-29. PMID:36446928. |
high frequency dbs-like optogenetic stimulation of nucleus accumbens dopamine d2 receptor-containing neurons attenuates cocaine reinstatement in male rats. |
2022-11-29 |
2023-08-14 |
rat |