| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thomas T Rudibaugh, Albert J Keun. Reactive Oxygen Species Mediate Transcriptional Responses to Dopamine and Cocaine in Human Cerebral Organoids. bioRxiv : the preprint server for biology. 2023-07-03. PMID:37398046. |
reactive oxygen species mediate transcriptional responses to dopamine and cocaine in human cerebral organoids. |
2023-07-03 |
2023-08-14 |
human |
| Thomas T Rudibaugh, Albert J Keun. Reactive Oxygen Species Mediate Transcriptional Responses to Dopamine and Cocaine in Human Cerebral Organoids. bioRxiv : the preprint server for biology. 2023-07-03. PMID:37398046. |
excessive dopamine levels including due to cocaine use both in utero and in adults could lead to long-term adverse consequences. |
2023-07-03 |
2023-08-14 |
human |
| Thomas T Rudibaugh, Albert J Keun. Reactive Oxygen Species Mediate Transcriptional Responses to Dopamine and Cocaine in Human Cerebral Organoids. bioRxiv : the preprint server for biology. 2023-07-03. PMID:37398046. |
in this study we utilize the xiang-tanaka ventral forebrain organoid model and characterize their response to acute and chronic dopamine or cocaine exposure. |
2023-07-03 |
2023-08-14 |
human |
| Verónica Pastor, Juliana F Dalto, Jorge H Medin. α7 nicotinic acetylcholine receptors in the medial prefrontal cortex control rewarding but not aversive memory expression in a dopamine-sensitive manner. Pharmacology, biochemistry, and behavior. 2023-06-29. PMID:37385456. |
we examined that question and found that dopamine type 1 receptor (d1r) activation prevented mla-induced blockade of cocaine cpp retrieval. |
2023-06-29 |
2023-08-14 |
Not clear |
| Mia I Allen, Angela N Duke, Susan H Nader, Adrienne Adler-Neal, Kiran K Solingapuram Sai, Beth A Reboussin, H Donald Gage, Ronald J Voll, Akiva Mintz, Mark M Goodman, Michael A Nade. PET imaging of dopamine transporters and D2/D3 receptors in female monkeys: effects of chronic cocaine self-administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-06-22. PMID:37349473. |
pet imaging of dopamine transporters and d2/d3 receptors in female monkeys: effects of chronic cocaine self-administration. |
2023-06-22 |
2023-08-14 |
human |
| Mia I Allen, Angela N Duke, Susan H Nader, Adrienne Adler-Neal, Kiran K Solingapuram Sai, Beth A Reboussin, H Donald Gage, Ronald J Voll, Akiva Mintz, Mark M Goodman, Michael A Nade. PET imaging of dopamine transporters and D2/D3 receptors in female monkeys: effects of chronic cocaine self-administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-06-22. PMID:37349473. |
brain imaging studies using positron emission tomography (pet) have shown that long-term cocaine use is associated with lower levels of dopamine (da) d2/d3 receptors (d2/d3r); less consistent are the effects on da transporter (dat) availability. |
2023-06-22 |
2023-08-14 |
human |
| N J Clauss, F P Mayer, W A Owens, M Vitela, K M Clarke, M A Bowman, R E Horton, D Gründemann, D Schmid, M Holy, G G Gould, W Koek, H H Sitte, L C Daw. Ethanol inhibits dopamine uptake via organic cation transporter 3: Implications for ethanol and cocaine co-abuse. Molecular psychiatry. 2023-06-12. PMID:37308680. |
ethanol inhibits dopamine uptake via organic cation transporter 3: implications for ethanol and cocaine co-abuse. |
2023-06-12 |
2023-08-14 |
mouse |
| N J Clauss, F P Mayer, W A Owens, M Vitela, K M Clarke, M A Bowman, R E Horton, D Gründemann, D Schmid, M Holy, G G Gould, W Koek, H H Sitte, L C Daw. Ethanol inhibits dopamine uptake via organic cation transporter 3: Implications for ethanol and cocaine co-abuse. Molecular psychiatry. 2023-06-12. PMID:37308680. |
cocaine increases extracellular monoamines by blocking dopamine (da), norepinephrine (ne) and serotonin (5-ht) transporters (dat, net and sert, respectively). |
2023-06-12 |
2023-08-14 |
mouse |
| Miguel Á Luján, Brandon L Oliver, Reana Young-Morrison, Sheila A Engi, Lan-Yuan Zhang, Jennifer M Wenzel, Yulong Li, Natalie E Zlebnik, Joseph F Chee. A multivariate regressor of patterned dopamine release predicts relapse to cocaine. Cell reports. vol 42. issue 6. 2023-05-24. PMID:37224011. |
a multivariate regressor of patterned dopamine release predicts relapse to cocaine. |
2023-05-24 |
2023-08-14 |
mouse |
| Miguel Á Luján, Brandon L Oliver, Reana Young-Morrison, Sheila A Engi, Lan-Yuan Zhang, Jennifer M Wenzel, Yulong Li, Natalie E Zlebnik, Joseph F Chee. A multivariate regressor of patterned dopamine release predicts relapse to cocaine. Cell reports. vol 42. issue 6. 2023-05-24. PMID:37224011. |
we reveal low-dimensional features of patterned dopamine release that are strong predictors of cue-induced reinstatement of cocaine seeking. |
2023-05-24 |
2023-08-14 |
mouse |
| Miguel Á Luján, Brandon L Oliver, Reana Young-Morrison, Sheila A Engi, Lan-Yuan Zhang, Jennifer M Wenzel, Yulong Li, Natalie E Zlebnik, Joseph F Chee. A multivariate regressor of patterned dopamine release predicts relapse to cocaine. Cell reports. vol 42. issue 6. 2023-05-24. PMID:37224011. |
these findings provide important insights into the sufficiency of nac dopamine signaling dynamics-in interaction with sex-for recapitulating persistent cocaine seeking and future relapse vulnerability. |
2023-05-24 |
2023-08-14 |
mouse |
| Caleigh Curran, Farideh Davoudi, Gabriel Foster, Patrick Gorda. Refractory bradycardia and hypotension in patients with autonomic dysfunction treated with pseudoephedrine. BMJ case reports. vol 16. issue 4. 2023-05-16. PMID:37185313. |
we describe a man in his 40s with a history of chronic intranasal cocaine use and c5-c7 incomplete quadriplegia complicated by neurogenic orthostatic hypotension, admitted to the intensive care unit for worsening bradycardia and hypotension requiring initiation of dopamine and an increase of his home midodrine dose. |
2023-05-16 |
2023-08-14 |
Not clear |
| Aliaa Mousa, Muhammad Humayoun Rashid, Syeda Neelam Yamin Bukhari, Mohammad Abu-Abaa, Karan H Pahuj. Chronic Cocaine Abuse as a Cause of Sinus Bradycardia. Cureus. vol 15. issue 4. 2023-05-16. PMID:37193419. |
common cardiovascular manifestations of cocaine are related to its adrenergic effects due to the inhibition of dopamine and norepinephrine uptake at the postsynaptic terminal. |
2023-05-16 |
2023-08-14 |
Not clear |
| Lauren M Burgeno, Ryan D Farero, Nicole L Murray, Marios C Panayi, Jennifer S Steger, Marta E Soden, Scott B Evans, Stefan G Sandberg, Ingo Willuhn, Larry S Zweifel, Paul E M Phillip. Cocaine Seeking And Taking Are Oppositely Regulated By Dopamine. bioRxiv : the preprint server for biology. 2023-04-24. PMID:37090565. |
cocaine seeking and taking are oppositely regulated by dopamine. |
2023-04-24 |
2023-08-14 |
Not clear |
| Michael Wolter, Thomas Lapointe, Nana Baidoo, Krista A Mitchnick, Cassidy Wideman, Boyer D Winters, Francesco Ler. Double dissociation of perirhinal nicotinic acetylcholine receptors and dopamine D2 receptors in modulation of object memory consolidation by nicotine, cocaine and their conditioned stimuli. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 72. 2023-04-22. PMID:37086715. |
double dissociation of perirhinal nicotinic acetylcholine receptors and dopamine d2 receptors in modulation of object memory consolidation by nicotine, cocaine and their conditioned stimuli. |
2023-04-22 |
2023-08-14 |
rat |
| Michael Wolter, Thomas Lapointe, Nana Baidoo, Krista A Mitchnick, Cassidy Wideman, Boyer D Winters, Francesco Ler. Double dissociation of perirhinal nicotinic acetylcholine receptors and dopamine D2 receptors in modulation of object memory consolidation by nicotine, cocaine and their conditioned stimuli. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 72. 2023-04-22. PMID:37086715. |
to directly test this hypothesis, a cholinergic nicotinic receptor antagonist (mecamylamine; mec: 0, 10 or 30 µg/side) and a dopamine d2 receptor antagonist (l-741,626: 0, 0.63, 2.5 µg/side) were infused in the perirhinal cortex (prh) to block modulation of object recognition memory consolidation induced by 0.4 mg/kg nicotine, 20 mg/kg cocaine, or their css. |
2023-04-22 |
2023-08-14 |
rat |
| Ying S Chao, Jeffrey Parrilla-Carrero, Maya Eid, Oliver P Culver, Tyler B Jackson, Rachel Lipat, Makoto Taniguchi, Thomas C Jho. Innate cocaine-seeking vulnerability arising from loss of serotonin-mediated aversive effects of cocaine in rats. Cell reports. vol 42. issue 5. 2023-04-21. PMID:37083325. |
cocaine blocks dopamine reuptake, thereby producing rewarding effects that are widely studied. |
2023-04-21 |
2023-08-14 |
rat |
| Ying S Chao, Jeffrey Parrilla-Carrero, Maya Eid, Oliver P Culver, Tyler B Jackson, Rachel Lipat, Makoto Taniguchi, Thomas C Jho. Innate cocaine-seeking vulnerability arising from loss of serotonin-mediated aversive effects of cocaine in rats. Cell reports. vol 42. issue 5. 2023-04-21. PMID:37083325. |
however, cocaine also blocks serotonin uptake, which we show drives, in rats, individually variable aversive effects that depend on serotonin 2c receptors (5-ht2crs) in the rostromedial tegmental nucleus (rmtg), a major gabaergic afferent to midbrain dopamine neurons. |
2023-04-21 |
2023-08-14 |
rat |
| Maxwell Miller, Alisa Zezetko, Ritvij Satodiy. Development of Atypical Neuroleptic Malignant Syndrome After Treatment of Cocaine Intoxication: A Case Report and Literature Review. Cureus. vol 15. issue 2. 2023-04-03. PMID:37007397. |
although overlapping dopamine pathways between cocaine use and nms could deter one from this practice and guidelines recommend against it, antipsychotics are routinely used in the emergency setting for cocaine-associated agitation. |
2023-04-03 |
2023-08-14 |
Not clear |
| Mark D Namba, Megan N Phillips, Peng-Jen Chen, Benjamin E Blass, M Foster Olive, Janet L Neisewande. HIV gp120 impairs nucleus accumbens neuroimmune function and dopamine D3 receptor-mediated inhibition of cocaine seeking in male rats. Addiction neuroscience. vol 5. 2023-03-13. PMID:36909738. |
hiv gp120 impairs nucleus accumbens neuroimmune function and dopamine d3 receptor-mediated inhibition of cocaine seeking in male rats. |
2023-03-13 |
2023-08-14 |
human |