| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ashley K Crawley, Anirudh Sharma, Kevin R Coffey, Mark O West, David J Barke. Nucleus accumbens shell neurons' early sensitivity to cocaine is associated with future increases in drug intake. Addiction neuroscience. vol 8. 2023-09-04. PMID:37664219. |
chronic consumption of abused substances, such as cocaine, can cause an oversaturation of mesostriatal dopamine, which results in alterations in the firing of striatal neurons. |
2023-09-04 |
2023-09-07 |
human |
| Mengfan Xia, Tanner A Anderson, Emily R Prantzalos, Tara R Hawkinson, Harrison A Clarke, Shannon B Keohane, Ramon C Sun, Jill R Turner, Pavel I Ortinsk. Voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-09-02. PMID:37660129. |
although astrocytes respond to dopamine and cocaine with structural changes, the impact of dopamine and cocaine on astrocyte functional plasticity has not been widely studied. |
2023-09-02 |
2023-09-07 |
Not clear |
| Mengfan Xia, Tanner A Anderson, Emily R Prantzalos, Tara R Hawkinson, Harrison A Clarke, Shannon B Keohane, Ramon C Sun, Jill R Turner, Pavel I Ortinsk. Voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-09-02. PMID:37660129. |
we characterized potassium channel function in nac astrocytes following exposure to exogenous dopamine or cocaine self-administration training under short (2 h/day) and extended (6 h/day) access schedules. |
2023-09-02 |
2023-09-07 |
Not clear |
| Jesús E Yepez, Jorge Juáre. Atomoxetine promotes incentive value of modafinil and sensitizes exploratory behavior. Pharmacology, biochemistry, and behavior. vol 230. 2023-08-20. PMID:37595803. |
the role of dopamine in the addictive effect of psychostimulants is well known; however, the involvement of the noradrenergic system is still unclear and poorly understood, though drugs like cocaine and amphetamines are known to exert significant activity on this system. |
2023-08-20 |
2023-09-07 |
rat |
| Daniele Zanella, Nicholas K Smith, J Andrew Hardaway, Anna Marie Buchanan, Clarence H Mullins, Aurelio Galli, Angela M Carte. Bile acids modulate reinstatement of cocaine conditioned place preference and accumbal dopamine dynamics without compromising appetitive learning. Scientific reports. vol 13. issue 1. 2023-08-17. PMID:37591972. |
bile acids modulate reinstatement of cocaine conditioned place preference and accumbal dopamine dynamics without compromising appetitive learning. |
2023-08-17 |
2023-09-07 |
mouse |
| Daniele Zanella, Nicholas K Smith, J Andrew Hardaway, Anna Marie Buchanan, Clarence H Mullins, Aurelio Galli, Angela M Carte. Bile acids modulate reinstatement of cocaine conditioned place preference and accumbal dopamine dynamics without compromising appetitive learning. Scientific reports. vol 13. issue 1. 2023-08-17. PMID:37591972. |
oca also impairs the ability of cocaine to reduce the clearance rate of electrically stimulated dopamine release and diminishes the area under the curve (auc) observed with amperometry. |
2023-08-17 |
2023-09-07 |
mouse |
| Eleanor Blair Towers, Ivy L Williams, Emaan I Qillawala, Wendy J Lync. Role of nucleus accumbens dopamine 2 receptors in motivating cocaine use in male and female rats prior to and following the development of an addiction-like phenotype. Frontiers in pharmacology. vol 14. 2023-08-11. PMID:37564182. |
role of nucleus accumbens dopamine 2 receptors in motivating cocaine use in male and female rats prior to and following the development of an addiction-like phenotype. |
2023-08-11 |
2023-08-16 |
human |
| Eleanor Blair Towers, Ivy L Williams, Emaan I Qillawala, Wendy J Lync. Role of nucleus accumbens dopamine 2 receptors in motivating cocaine use in male and female rats prior to and following the development of an addiction-like phenotype. Frontiers in pharmacology. vol 14. 2023-08-11. PMID:37564182. |
a hallmark of cocaine use disorder (cud) is dysfunction of dopamine signaling in the mesolimbic pathway, including impaired dopamine 2 (d2) receptor signaling. |
2023-08-11 |
2023-08-16 |
human |
| Brooke N Bender, Sierra J Stringfield, Mary M Torregross. Changes in dorsomedial striatum activity mediate expression of goal-directed vs. habit-like cue-induced cocaine seeking. bioRxiv : the preprint server for biology. 2023-08-07. PMID:37546826. |
we used fiber photometry to examine how dorsal striatal intracellular calcium and extracellular dopamine activity differs between goal-directed and habitual cue-induced cocaine seeking and how it is impacted by cue extinction. |
2023-08-07 |
2023-08-14 |
rat |
| Brooke N Bender, Sierra J Stringfield, Mary M Torregross. Changes in dorsomedial striatum activity mediate expression of goal-directed vs. habit-like cue-induced cocaine seeking. bioRxiv : the preprint server for biology. 2023-08-07. PMID:37546826. |
rats trained to self-administer cocaine paired with an audiovisual cue on schedules of reinforcement that promote goal-directed or habitual cocaine seeking had different patterns of dorsal striatal calcium and dopamine responses to cue-reinforced lever presses. |
2023-08-07 |
2023-08-14 |
rat |
| Samara Vilca, Claes Wahlestedt, Sari Izenwasser, Raul R Gainetdinov, Marta Pard. Dopamine Transporter Knockout Rats Display Epigenetic Alterations in Response to Cocaine Exposure. Biomolecules. vol 13. issue 7. 2023-07-29. PMID:37509143. |
dopamine transporter knockout rats display epigenetic alterations in response to cocaine exposure. |
2023-07-29 |
2023-08-14 |
rat |
| Melinda Hersey, Andy Y Chen, Mattingly K Bartole, Jayati Anand, Amy Hauck Newman, Gianluigi Tand. An FSCV Study on the Effects of Targeted Typical and Atypical DAT Inhibition on Dopamine Dynamics in the Nucleus Accumbens Shell of Male and Female Mice. ACS chemical neuroscience. 2023-07-19. PMID:37466616. |
many psychostimulants, like cocaine, inhibit the dopamine transporter (dat), which is largely thought to account for actions related to their misuse and dependence. |
2023-07-19 |
2023-08-14 |
mouse |
| Aurelio Franco-García, Rocío Guerrero-Bautista, Juana María Hidalgo, Victoria Gómez-Murcia, María Victoria Milanés, Cristina Núñe. Dopamine D3 Receptor Modulates Akt/mTOR and ERK International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37446391. |
dopamine d3 receptor modulates akt/mtor and erk stress triggers relapses in cocaine use that engage the activity of memory-related nuclei, such as the basolateral amygdala (bla) and dentate gyrus (dg). |
2023-07-14 |
2023-08-14 |
Not clear |
| Marco Leyton, Maja Nikoli. A non-human primate model of cocaine addiction: interpreting associations with increased vs. decreased dopamine function. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-07-12. PMID:37438420. |
a non-human primate model of cocaine addiction: interpreting associations with increased vs. decreased dopamine function. |
2023-07-12 |
2023-08-14 |
Not clear |
| Thomas T Rudibaugh, Albert J Keun. Reactive Oxygen Species Mediate Transcriptional Responses to Dopamine and Cocaine in Human Cerebral Organoids. bioRxiv : the preprint server for biology. 2023-07-03. PMID:37398046. |
reactive oxygen species mediate transcriptional responses to dopamine and cocaine in human cerebral organoids. |
2023-07-03 |
2023-08-14 |
human |
| Thomas T Rudibaugh, Albert J Keun. Reactive Oxygen Species Mediate Transcriptional Responses to Dopamine and Cocaine in Human Cerebral Organoids. bioRxiv : the preprint server for biology. 2023-07-03. PMID:37398046. |
excessive dopamine levels including due to cocaine use both in utero and in adults could lead to long-term adverse consequences. |
2023-07-03 |
2023-08-14 |
human |
| Thomas T Rudibaugh, Albert J Keun. Reactive Oxygen Species Mediate Transcriptional Responses to Dopamine and Cocaine in Human Cerebral Organoids. bioRxiv : the preprint server for biology. 2023-07-03. PMID:37398046. |
in this study we utilize the xiang-tanaka ventral forebrain organoid model and characterize their response to acute and chronic dopamine or cocaine exposure. |
2023-07-03 |
2023-08-14 |
human |
| Verónica Pastor, Juliana F Dalto, Jorge H Medin. α7 nicotinic acetylcholine receptors in the medial prefrontal cortex control rewarding but not aversive memory expression in a dopamine-sensitive manner. Pharmacology, biochemistry, and behavior. 2023-06-29. PMID:37385456. |
we examined that question and found that dopamine type 1 receptor (d1r) activation prevented mla-induced blockade of cocaine cpp retrieval. |
2023-06-29 |
2023-08-14 |
Not clear |
| Mia I Allen, Angela N Duke, Susan H Nader, Adrienne Adler-Neal, Kiran K Solingapuram Sai, Beth A Reboussin, H Donald Gage, Ronald J Voll, Akiva Mintz, Mark M Goodman, Michael A Nade. PET imaging of dopamine transporters and D2/D3 receptors in female monkeys: effects of chronic cocaine self-administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-06-22. PMID:37349473. |
pet imaging of dopamine transporters and d2/d3 receptors in female monkeys: effects of chronic cocaine self-administration. |
2023-06-22 |
2023-08-14 |
human |
| Mia I Allen, Angela N Duke, Susan H Nader, Adrienne Adler-Neal, Kiran K Solingapuram Sai, Beth A Reboussin, H Donald Gage, Ronald J Voll, Akiva Mintz, Mark M Goodman, Michael A Nade. PET imaging of dopamine transporters and D2/D3 receptors in female monkeys: effects of chronic cocaine self-administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-06-22. PMID:37349473. |
brain imaging studies using positron emission tomography (pet) have shown that long-term cocaine use is associated with lower levels of dopamine (da) d2/d3 receptors (d2/d3r); less consistent are the effects on da transporter (dat) availability. |
2023-06-22 |
2023-08-14 |
human |