| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marina Bellot, Fernando Soria, Raul López-Arnau, Cristian Gómez-Canela, Carlos Barat. Daphnia magna an emerging environmental model of neuro and cardiotoxicity of illicit drugs. Environmental pollution (Barking, Essex : 1987). 2024-01-16. PMID:38228265. |
observed effects on neurotransmitters and related metabolites were in concern with reported responses in mammalian and other vertebrate models: cocaine and mdma enhanced dopamine and serotonin levels, respectively, methamphetamine and mdma decreased dopamine and octopamine, and all but mdma decreased 3 mt levels. |
2024-01-16 |
2024-01-19 |
Not clear |
| Jocelyn A Ricard, Loïc Labache, Ashlea Segal, Elvisha Dhamala, Carrisa V Cocuzza, Grant Jones, Sarah Yip, Sidhant Chopra, Avram J Holme. A shared spatial topography links the functional connectome correlates of cocaine use disorder and dopamine D bioRxiv : the preprint server for biology. 2023-12-04. PMID:38045392. |
a shared spatial topography links the functional connectome correlates of cocaine use disorder and dopamine d the biological mechanisms that contribute to cocaine and other substance use disorders involve an array of cortical and subcortical systems. |
2023-12-04 |
2023-12-10 |
Not clear |
| Dan Bi Ahn, Han Byeol Jang, Yeonhee Ryu, Hyung Kyu Kim, Xiaowei Guan, Yu Fan, Bae Hwan Lee, Hee Young Ki. A hypothalamus-habenula circuit regulates psychomotor responses induced by cocaine. Addiction biology. vol 28. issue 12. 2023-11-29. PMID:38017642. |
administration of cocaine increases synaptic dopamine levels by blocking dopamine reuptake and leads to increased locomotor activity and compulsive drug-seeking behaviour. |
2023-11-30 |
2023-12-07 |
Not clear |
| Dan Bi Ahn, Han Byeol Jang, Yeonhee Ryu, Hyung Kyu Kim, Xiaowei Guan, Yu Fan, Bae Hwan Lee, Hee Young Ki. A hypothalamus-habenula circuit regulates psychomotor responses induced by cocaine. Addiction biology. vol 28. issue 12. 2023-11-29. PMID:38017642. |
administration of cocaine increases synaptic dopamine levels by blocking dopamine reuptake and leads to increased locomotor activity and compulsive drug-seeking behaviour. |
2023-11-29 |
2023-12-07 |
Not clear |
| Thomas T Rudibaugh, Samantha R Stuppy, Albert J Keun. Reactive Oxygen Species Mediate Transcriptional Responses to Dopamine and Cocaine in Human Cerebral Organoids. International journal of molecular sciences. vol 24. issue 22. 2023-11-25. PMID:38003664. |
reactive oxygen species mediate transcriptional responses to dopamine and cocaine in human cerebral organoids. |
2023-11-25 |
2023-11-28 |
human |
| Thomas T Rudibaugh, Samantha R Stuppy, Albert J Keun. Reactive Oxygen Species Mediate Transcriptional Responses to Dopamine and Cocaine in Human Cerebral Organoids. International journal of molecular sciences. vol 24. issue 22. 2023-11-25. PMID:38003664. |
excessive dopamine levels, including those due to cocaine use in utero and in adults, could lead to long-term adverse consequences. |
2023-11-25 |
2023-11-28 |
human |
| Thomas T Rudibaugh, Samantha R Stuppy, Albert J Keun. Reactive Oxygen Species Mediate Transcriptional Responses to Dopamine and Cocaine in Human Cerebral Organoids. International journal of molecular sciences. vol 24. issue 22. 2023-11-25. PMID:38003664. |
in this study, we use the human-derived ventral forebrain organoid model of xiang-tanaka and characterize their response to cocaine or dopamine. |
2023-11-25 |
2023-11-28 |
human |
| Thomas T Rudibaugh, Samantha R Stuppy, Albert J Keun. Reactive Oxygen Species Mediate Transcriptional Responses to Dopamine and Cocaine in Human Cerebral Organoids. International journal of molecular sciences. vol 24. issue 22. 2023-11-25. PMID:38003664. |
we explore dosing regimens of dopamine or cocaine to simulate acute or chronic exposure. |
2023-11-25 |
2023-11-28 |
human |
| Thomas T Rudibaugh, Samantha R Stuppy, Albert J Keun. Reactive Oxygen Species Mediate Transcriptional Responses to Dopamine and Cocaine in Human Cerebral Organoids. International journal of molecular sciences. vol 24. issue 22. 2023-11-25. PMID:38003664. |
we then use calcium imaging, camp imaging, and bulk rna-sequencing to measure responses to cocaine or dopamine exposure. |
2023-11-25 |
2023-11-28 |
human |
| Emily M Black, Shanna B Samels, Wei Xu, Jessica R Barson, Caroline E Bass, Sandhya Kortagere, Rodrigo A Españ. Hypocretin / Orexin Receptor 1 Knockdown in GABA or Dopamine Neurons in the Ventral Tegmental Area Differentially Impact Mesolimbic Dopamine and Motivation for Cocaine. Addiction neuroscience. vol 7. 2023-10-20. PMID:37854172. |
hypocretin / orexin receptor 1 knockdown in gaba or dopamine neurons in the ventral tegmental area differentially impact mesolimbic dopamine and motivation for cocaine. |
2023-10-20 |
2023-11-08 |
rat |
| Emily M Black, Shanna B Samels, Wei Xu, Jessica R Barson, Caroline E Bass, Sandhya Kortagere, Rodrigo A Españ. Hypocretin / Orexin Receptor 1 Knockdown in GABA or Dopamine Neurons in the Ventral Tegmental Area Differentially Impact Mesolimbic Dopamine and Motivation for Cocaine. Addiction neuroscience. vol 7. 2023-10-20. PMID:37854172. |
the hypocretins/orexins (hcrt) have been demonstrated to influence motivation for cocaine through actions on dopamine (da) transmission. |
2023-10-20 |
2023-11-08 |
rat |
| Lianwei Mu, Xiaojie Liu, Hao Yu, Casey R Vickstrom, Vladislav Friedman, Thomas J Kelly, Ying Hu, Wantang Su, Shuai Liu, John R Mantsch, Qing-Song Li. cAMP-mediated upregulation of HCN channels in VTA dopamine neurons promotes cocaine reinforcement. Molecular psychiatry. 2023-10-16. PMID:37845497. |
camp-mediated upregulation of hcn channels in vta dopamine neurons promotes cocaine reinforcement. |
2023-10-16 |
2023-11-08 |
rat |
| Mark Froimowitz, Rosa Taboada, Zachary J Poulos, Dominic J Rainone, Gregory H Imler, Eliot L Gardner, Charles J Kelle. Chiral Resolution of the Enantiomers of the Slow-Onset Dopamine Reuptake Inhibitor CTDP-32476 and Their Activities. ACS omega. vol 8. issue 39. 2023-10-09. PMID:37810691. |
an improved synthesis was developed for cdtp-32476, a potent slow-onset dopamine reuptake blocker that may have utility as a treatment for cocaine abuse. |
2023-10-09 |
2023-10-15 |
Not clear |
| Suchan Chang, Hyung Kyu Kim, Yeonhee Ryu, Han Byeol Jang, DanBi Ahn, Bong Hyo Lee, Dong-Ho Youn, Bae Hwan Lee, Hee Young Ki. Mediation of mPFC-LHb pathway in acupuncture inhibition of cocaine psychomotor activity. Addiction biology. vol 28. issue 10. 2023-09-27. PMID:37753567. |
ht7 acupuncture suppressed nac dopamine release following cocaine injection, which was blocked by electrolytic lesion of mpfc. |
2023-09-27 |
2023-10-07 |
rat |
| Kanako Matsumura, Amélia Nicot, In Bae Choi, Meera Asokan, Nathan N Le, Luis A Natividad, Lauren K Dobb. Endogenous opioid system modulates conditioned cocaine reward in a sex-dependent manner. Addiction biology. vol 28. issue 10. 2023-09-27. PMID:37753570. |
to address this, we generated mice with a targeted deletion of enkephalin from dopamine d2-receptor expressing medium spiny neurons and tested them in a cocaine cpp paradigm. |
2023-09-27 |
2023-10-07 |
mouse |
| Armando G Salinas, Jeong Oen Lee, Shana M Augustin, Shiliang Zhang, Tommaso Patriarchi, Lin Tian, Marisela Morales, Yolanda Mateo, David M Lovinge. Distinct sub-second dopamine signaling in dorsolateral striatum measured by a genetically-encoded fluorescent sensor. Nature communications. vol 14. issue 1. 2023-09-22. PMID:37739964. |
to test this, we first evaluated dlight photometry in mouse brain slices with simultaneous fscv and found that both techniques yielded comparable results, but notable differences in responses to dopamine transporter inhibitors, including cocaine. |
2023-09-22 |
2023-10-07 |
mouse |
| Mia I Allen, Bernard N Johnson, Michael A Nade. A comparison of the reinforcing strength of cocaethylene and cocaine in monkeys responding under progressive-ratio and concurrent choice schedules of reinforcement. Drug and alcohol dependence. vol 251. 2023-09-12. PMID:37699287. |
cocaethylene is equipotent to cocaine in blocking dopamine reuptake and substitutes for cocaine in drug discrimination studies. |
2023-09-12 |
2023-10-07 |
monkey |
| Ginna Urueña-Méndez, Andrea Dimiziani, Lidia Bellés, Raphaël Goutaudier, Nathalie Ginovar. Repeated Cocaine Intake Differentially Impacts Striatal D International journal of molecular sciences. vol 24. issue 17. 2023-09-09. PMID:37686044. |
repeated cocaine intake differentially impacts striatal d current research indicates that altered dopamine (da) transmission in the striatum contributes to impulsivity and novelty-seeking, and it may mediate a link concerning a higher susceptibility to drug abuse. |
2023-09-09 |
2023-10-07 |
Not clear |
| Tristan J Hynes, Chloe S Chernoff, Kelly M Hrelja, Maric T L Tse, Dimitrios Avramidis, Melanie R Lysenko-Martin, Lucas Calderhead, Sukhbir Kaur, Stan B Floresco, Catharine A Winstanle. Win-paired cues modulate the effect of dopamine neuron sensitization on decision making and cocaine self-administration: divergent effects across sex. Biological psychiatry. 2023-09-06. PMID:37673411. |
win-paired cues modulate the effect of dopamine neuron sensitization on decision making and cocaine self-administration: divergent effects across sex. |
2023-09-06 |
2023-10-07 |
Not clear |
| Dana M Smith, Mary M Torregross. The ventral tegmental area dopamine to lateral amygdala projection supports cocaine cue associative learning. bioRxiv : the preprint server for biology. 2023-09-04. PMID:37662292. |
the ventral tegmental area dopamine to lateral amygdala projection supports cocaine cue associative learning. |
2023-09-04 |
2023-09-07 |
Not clear |