Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Kanako Matsumura, Amélia Nicot, In Bae Choi, Meera Asokan, Nathan N Le, Luis A Natividad, Lauren K Dobb. Endogenous opioid system modulates conditioned cocaine reward in a sex-dependent manner. Addiction biology. vol 28. issue 10. 2023-09-27. PMID:37753570. |
to address this, we generated mice with a targeted deletion of enkephalin from dopamine d2-receptor expressing medium spiny neurons and tested them in a cocaine cpp paradigm. |
2023-09-27 |
2023-10-07 |
mouse |
Armando G Salinas, Jeong Oen Lee, Shana M Augustin, Shiliang Zhang, Tommaso Patriarchi, Lin Tian, Marisela Morales, Yolanda Mateo, David M Lovinge. Distinct sub-second dopamine signaling in dorsolateral striatum measured by a genetically-encoded fluorescent sensor. Nature communications. vol 14. issue 1. 2023-09-22. PMID:37739964. |
to test this, we first evaluated dlight photometry in mouse brain slices with simultaneous fscv and found that both techniques yielded comparable results, but notable differences in responses to dopamine transporter inhibitors, including cocaine. |
2023-09-22 |
2023-10-07 |
mouse |
Mia I Allen, Bernard N Johnson, Michael A Nade. A comparison of the reinforcing strength of cocaethylene and cocaine in monkeys responding under progressive-ratio and concurrent choice schedules of reinforcement. Drug and alcohol dependence. vol 251. 2023-09-12. PMID:37699287. |
cocaethylene is equipotent to cocaine in blocking dopamine reuptake and substitutes for cocaine in drug discrimination studies. |
2023-09-12 |
2023-10-07 |
monkey |
Ginna Urueña-Méndez, Andrea Dimiziani, Lidia Bellés, Raphaël Goutaudier, Nathalie Ginovar. Repeated Cocaine Intake Differentially Impacts Striatal D International journal of molecular sciences. vol 24. issue 17. 2023-09-09. PMID:37686044. |
repeated cocaine intake differentially impacts striatal d current research indicates that altered dopamine (da) transmission in the striatum contributes to impulsivity and novelty-seeking, and it may mediate a link concerning a higher susceptibility to drug abuse. |
2023-09-09 |
2023-10-07 |
Not clear |
Tristan J Hynes, Chloe S Chernoff, Kelly M Hrelja, Maric T L Tse, Dimitrios Avramidis, Melanie R Lysenko-Martin, Lucas Calderhead, Sukhbir Kaur, Stan B Floresco, Catharine A Winstanle. Win-paired cues modulate the effect of dopamine neuron sensitization on decision making and cocaine self-administration: divergent effects across sex. Biological psychiatry. 2023-09-06. PMID:37673411. |
win-paired cues modulate the effect of dopamine neuron sensitization on decision making and cocaine self-administration: divergent effects across sex. |
2023-09-06 |
2023-10-07 |
Not clear |
Dana M Smith, Mary M Torregross. The ventral tegmental area dopamine to lateral amygdala projection supports cocaine cue associative learning. bioRxiv : the preprint server for biology. 2023-09-04. PMID:37662292. |
the ventral tegmental area dopamine to lateral amygdala projection supports cocaine cue associative learning. |
2023-09-04 |
2023-09-07 |
Not clear |
Ashley K Crawley, Anirudh Sharma, Kevin R Coffey, Mark O West, David J Barke. Nucleus accumbens shell neurons' early sensitivity to cocaine is associated with future increases in drug intake. Addiction neuroscience. vol 8. 2023-09-04. PMID:37664219. |
chronic consumption of abused substances, such as cocaine, can cause an oversaturation of mesostriatal dopamine, which results in alterations in the firing of striatal neurons. |
2023-09-04 |
2023-09-07 |
human |
Mengfan Xia, Tanner A Anderson, Emily R Prantzalos, Tara R Hawkinson, Harrison A Clarke, Shannon B Keohane, Ramon C Sun, Jill R Turner, Pavel I Ortinsk. Voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-09-02. PMID:37660129. |
although astrocytes respond to dopamine and cocaine with structural changes, the impact of dopamine and cocaine on astrocyte functional plasticity has not been widely studied. |
2023-09-02 |
2023-09-07 |
Not clear |
Mengfan Xia, Tanner A Anderson, Emily R Prantzalos, Tara R Hawkinson, Harrison A Clarke, Shannon B Keohane, Ramon C Sun, Jill R Turner, Pavel I Ortinsk. Voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-09-02. PMID:37660129. |
we characterized potassium channel function in nac astrocytes following exposure to exogenous dopamine or cocaine self-administration training under short (2 h/day) and extended (6 h/day) access schedules. |
2023-09-02 |
2023-09-07 |
Not clear |
Jesús E Yepez, Jorge Juáre. Atomoxetine promotes incentive value of modafinil and sensitizes exploratory behavior. Pharmacology, biochemistry, and behavior. vol 230. 2023-08-20. PMID:37595803. |
the role of dopamine in the addictive effect of psychostimulants is well known; however, the involvement of the noradrenergic system is still unclear and poorly understood, though drugs like cocaine and amphetamines are known to exert significant activity on this system. |
2023-08-20 |
2023-09-07 |
rat |
Daniele Zanella, Nicholas K Smith, J Andrew Hardaway, Anna Marie Buchanan, Clarence H Mullins, Aurelio Galli, Angela M Carte. Bile acids modulate reinstatement of cocaine conditioned place preference and accumbal dopamine dynamics without compromising appetitive learning. Scientific reports. vol 13. issue 1. 2023-08-17. PMID:37591972. |
bile acids modulate reinstatement of cocaine conditioned place preference and accumbal dopamine dynamics without compromising appetitive learning. |
2023-08-17 |
2023-09-07 |
mouse |
Daniele Zanella, Nicholas K Smith, J Andrew Hardaway, Anna Marie Buchanan, Clarence H Mullins, Aurelio Galli, Angela M Carte. Bile acids modulate reinstatement of cocaine conditioned place preference and accumbal dopamine dynamics without compromising appetitive learning. Scientific reports. vol 13. issue 1. 2023-08-17. PMID:37591972. |
oca also impairs the ability of cocaine to reduce the clearance rate of electrically stimulated dopamine release and diminishes the area under the curve (auc) observed with amperometry. |
2023-08-17 |
2023-09-07 |
mouse |
Eleanor Blair Towers, Ivy L Williams, Emaan I Qillawala, Wendy J Lync. Role of nucleus accumbens dopamine 2 receptors in motivating cocaine use in male and female rats prior to and following the development of an addiction-like phenotype. Frontiers in pharmacology. vol 14. 2023-08-11. PMID:37564182. |
role of nucleus accumbens dopamine 2 receptors in motivating cocaine use in male and female rats prior to and following the development of an addiction-like phenotype. |
2023-08-11 |
2023-08-16 |
human |
Eleanor Blair Towers, Ivy L Williams, Emaan I Qillawala, Wendy J Lync. Role of nucleus accumbens dopamine 2 receptors in motivating cocaine use in male and female rats prior to and following the development of an addiction-like phenotype. Frontiers in pharmacology. vol 14. 2023-08-11. PMID:37564182. |
a hallmark of cocaine use disorder (cud) is dysfunction of dopamine signaling in the mesolimbic pathway, including impaired dopamine 2 (d2) receptor signaling. |
2023-08-11 |
2023-08-16 |
human |
Brooke N Bender, Sierra J Stringfield, Mary M Torregross. Changes in dorsomedial striatum activity mediate expression of goal-directed vs. habit-like cue-induced cocaine seeking. bioRxiv : the preprint server for biology. 2023-08-07. PMID:37546826. |
we used fiber photometry to examine how dorsal striatal intracellular calcium and extracellular dopamine activity differs between goal-directed and habitual cue-induced cocaine seeking and how it is impacted by cue extinction. |
2023-08-07 |
2023-08-14 |
rat |
Brooke N Bender, Sierra J Stringfield, Mary M Torregross. Changes in dorsomedial striatum activity mediate expression of goal-directed vs. habit-like cue-induced cocaine seeking. bioRxiv : the preprint server for biology. 2023-08-07. PMID:37546826. |
rats trained to self-administer cocaine paired with an audiovisual cue on schedules of reinforcement that promote goal-directed or habitual cocaine seeking had different patterns of dorsal striatal calcium and dopamine responses to cue-reinforced lever presses. |
2023-08-07 |
2023-08-14 |
rat |
Samara Vilca, Claes Wahlestedt, Sari Izenwasser, Raul R Gainetdinov, Marta Pard. Dopamine Transporter Knockout Rats Display Epigenetic Alterations in Response to Cocaine Exposure. Biomolecules. vol 13. issue 7. 2023-07-29. PMID:37509143. |
dopamine transporter knockout rats display epigenetic alterations in response to cocaine exposure. |
2023-07-29 |
2023-08-14 |
rat |
Melinda Hersey, Andy Y Chen, Mattingly K Bartole, Jayati Anand, Amy Hauck Newman, Gianluigi Tand. An FSCV Study on the Effects of Targeted Typical and Atypical DAT Inhibition on Dopamine Dynamics in the Nucleus Accumbens Shell of Male and Female Mice. ACS chemical neuroscience. 2023-07-19. PMID:37466616. |
many psychostimulants, like cocaine, inhibit the dopamine transporter (dat), which is largely thought to account for actions related to their misuse and dependence. |
2023-07-19 |
2023-08-14 |
mouse |
Aurelio Franco-García, Rocío Guerrero-Bautista, Juana María Hidalgo, Victoria Gómez-Murcia, María Victoria Milanés, Cristina Núñe. Dopamine D3 Receptor Modulates Akt/mTOR and ERK International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37446391. |
dopamine d3 receptor modulates akt/mtor and erk stress triggers relapses in cocaine use that engage the activity of memory-related nuclei, such as the basolateral amygdala (bla) and dentate gyrus (dg). |
2023-07-14 |
2023-08-14 |
Not clear |
Marco Leyton, Maja Nikoli. A non-human primate model of cocaine addiction: interpreting associations with increased vs. decreased dopamine function. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-07-12. PMID:37438420. |
a non-human primate model of cocaine addiction: interpreting associations with increased vs. decreased dopamine function. |
2023-07-12 |
2023-08-14 |
Not clear |